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The map label for this gene is serB [H]

Identifier: 121611783

GI number: 121611783

Start: 5401601

End: 5402395

Strand: Direct

Name: serB [H]

Synonym: Veis_4883

Alternate gene names: 121611783

Gene position: 5401601-5402395 (Clockwise)

Preceding gene: 121611782

Following gene: 121611785

Centisome position: 97.03

GC content: 67.92

Gene sequence:

>795_bases
ATGATCGGCACCATTGAAGCCTTCTCGCCCCGCGACACCCGTGCGCGCAGGTCTGACCCCACGGCACCAGGGCCGGCGGC
CCACTCGCGCGCGCGCGAATTCGCCCCCGGCCTGCTCGTCCAGGGCATCGCGCCCCCGCTGTCCCTGTCGAGCTACAAGC
TGATCGCGTTCGACATGGACTCGACCCTCATCAACATCGAGTGCGTCGATGAAATCGCCGACGCCGCAGGCCGCAAGGCC
GAAGTGGCTGCCATCACCGAGGCGGCGATGCAGGGCCTGGTCACCGACTACAAGGAAAGCCTGCGCCAGCGCGTGGCCCT
GCTCAAGGGCGTGACGGTGCAGCGCATGCAGCAACTGCTGACCGAACGCCTGCGCCTGAACCCCGGCGCCAAGGAACTCG
TCACCGCCGTCAAGGCCGCCGGCCTGCGCACGCTGCTGGTGTCGGGCGGCTTCAGCTTTTTTGCCGACCATGTGCGTGCG
ATCCTGGGCATAGACTTTGCCCGCTCCAACCGGCTGGAACTGGACAACGGCCAGCTCACCGGCCGCATGCTGGAGCAAAC
CTGGGGCGACCTGTGCGACGGCGCAGAAAAGCGCCGCACCTTGCTGGAACTGGCATCGCTGATGGGCATTTCACCCGCGC
AGACGATTGCCGTCGGCGATGGCGCCAACGACCTGCCGATGATGGCCGCCGCCGGCCTGTCGGTGGCCTACCACGCCAAG
CCCGCCGTGCGCGCGCAGGCCAAGGTGGCGATCAACCAGGGCGGGCTGGACCGACTGCTGGAAGTGCTGCACTGA

Upstream 100 bases:

>100_bases
CCGGGCGCGGAATCGGGCGTGCAATGCCCCCTCGTTGCGGCCCGCAGGCCCAGGCCCTGCGCTGGCGCCGTTGCCCTGTA
CCTTCTTCCACCCTCCGAGC

Downstream 100 bases:

>100_bases
ACGGCCCCGCCAGCACCTGCGCAACCAACCGGCCTCGGGCAACGGCGCAAAGGCAAAGGCCAGCCCGACCCGATGGCAGC
GCGCAGCAGGCCGCAAGGGT

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MIGTIEAFSPRDTRARRSDPTAPGPAAHSRAREFAPGLLVQGIAPPLSLSSYKLIAFDMDSTLINIECVDEIADAAGRKA
EVAAITEAAMQGLVTDYKESLRQRVALLKGVTVQRMQQLLTERLRLNPGAKELVTAVKAAGLRTLLVSGGFSFFADHVRA
ILGIDFARSNRLELDNGQLTGRMLEQTWGDLCDGAEKRRTLLELASLMGISPAQTIAVGDGANDLPMMAAAGLSVAYHAK
PAVRAQAKVAINQGGLDRLLEVLH

Sequences:

>Translated_264_residues
MIGTIEAFSPRDTRARRSDPTAPGPAAHSRAREFAPGLLVQGIAPPLSLSSYKLIAFDMDSTLINIECVDEIADAAGRKA
EVAAITEAAMQGLVTDYKESLRQRVALLKGVTVQRMQQLLTERLRLNPGAKELVTAVKAAGLRTLLVSGGFSFFADHVRA
ILGIDFARSNRLELDNGQLTGRMLEQTWGDLCDGAEKRRTLLELASLMGISPAQTIAVGDGANDLPMMAAAGLSVAYHAK
PAVRAQAKVAINQGGLDRLLEVLH
>Mature_264_residues
MIGTIEAFSPRDTRARRSDPTAPGPAAHSRAREFAPGLLVQGIAPPLSLSSYKLIAFDMDSTLINIECVDEIADAAGRKA
EVAAITEAAMQGLVTDYKESLRQRVALLKGVTVQRMQQLLTERLRLNPGAKELVTAVKAAGLRTLLVSGGFSFFADHVRA
ILGIDFARSNRLELDNGQLTGRMLEQTWGDLCDGAEKRRTLLELASLMGISPAQTIAVGDGANDLPMMAAAGLSVAYHAK
PAVRAQAKVAINQGGLDRLLEVLH

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=198, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1790849, Length=203, Percent_Identity=46.7980295566502, Blast_Score=168, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6321647, Length=212, Percent_Identity=40.0943396226415, Blast_Score=149, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24661601, Length=126, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 28225; Mature: 28225

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGTIEAFSPRDTRARRSDPTAPGPAAHSRAREFAPGLLVQGIAPPLSLSSYKLIAFDMD
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEEEECC
STLINIECVDEIADAAGRKAEVAAITEAAMQGLVTDYKESLRQRVALLKGVTVQRMQQLL
CEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TERLRLNPGAKELVTAVKAAGLRTLLVSGGFSFFADHVRAILGIDFARSNRLELDNGQLT
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCCCHHH
GRMLEQTWGDLCDGAEKRRTLLELASLMGISPAQTIAVGDGANDLPMMAAAGLSVAYHAK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCHHEECCC
PAVRAQAKVAINQGGLDRLLEVLH
CHHHHHHHHEECCCCHHHHHHHHC
>Mature Secondary Structure
MIGTIEAFSPRDTRARRSDPTAPGPAAHSRAREFAPGLLVQGIAPPLSLSSYKLIAFDMD
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEEEECC
STLINIECVDEIADAAGRKAEVAAITEAAMQGLVTDYKESLRQRVALLKGVTVQRMQQLL
CEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TERLRLNPGAKELVTAVKAAGLRTLLVSGGFSFFADHVRAILGIDFARSNRLELDNGQLT
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCCCHHH
GRMLEQTWGDLCDGAEKRRTLLELASLMGISPAQTIAVGDGANDLPMMAAAGLSVAYHAK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCHHEECCC
PAVRAQAKVAINQGGLDRLLEVLH
CHHHHHHHHEECCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]