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The map label for this gene is hipO [H]

Identifier: 121611782

GI number: 121611782

Start: 5400237

End: 5401451

Strand: Direct

Name: hipO [H]

Synonym: Veis_4882

Alternate gene names: 121611782

Gene position: 5400237-5401451 (Clockwise)

Preceding gene: 121611781

Following gene: 121611783

Centisome position: 97.01

GC content: 66.34

Gene sequence:

>1215_bases
ATGAACGTCATTGACTCCATCGTCACCCAGGCGGCCAGCATTGCCGCAGTGCGCCGGGACATCCACGCCCACCCCGAGCT
GTGCTTCGAAGAGCGGCGCACCGCCGATGTGGTGGCGCAAAAGCTCACCGAGTGGGGCATTCCGATCCACCGGGGGCTGG
GCAAGACCGGCGTGGTCGGCATCGTCAAGGGGCGTGATGGCGGCGCCAGCGGTCGGGCCGTTGGCCTGCGCGCCGACATC
GACGCCCTGCCGATGCAAGAGTTCAACAGCTTCGCCCATGCCAGCCGGCACCAGGGCAAGATGCACGCCTGCGGCCACGA
CGGCCACACGGCCATGCTGCTGGCTGCGGCGCAGCACTTTGCGCAGCACCGCCCGTTCGACGGCACCGTGTACCTGATCT
TCCAGCCCGCAGAAGAAGGCGGCGGCGGCGCCCGCGTGATGATCGAAGACGGCCTGTTCGAGCAATTTCCGATGCAGGCC
GTGTTCGGCATGCACAACTGGCCGGGCATGCCCGTCGGCAGTTTTGCCGTCAGCCCCGGCCCCGTGATGGCCTCGACCAG
CGAATTCCGGATCACCATCCGGGGCAAGGGCGGCCATGCCGCATTGCCGCATACGGGCATCGACCCGGTGCCGATTGCCT
GCCAGATGGTGCAGACCTTCCAGACCATCATCAGCCGCAACAAAAAGCCGGTGGATGCAGGCGTGATCTCGGTGACCATG
GTGCATGCGGGCGAGGCCACCAACGTGGTACCCGACAGTTGCGAACTGCGGGGCACGGTGCGCGCCTTCACCATCGAGGT
GCGCGACCTGATCGAAAAACGCATGCGGCAGGTGGCCGAGCACAGTTGCGCGGCGCATGGTGCCGTTTGCGAGTTCGAGT
TCGTGCGCAACTACCCGCCGACCATCAACTCGCCCGCCGAGACGGAGTTCGTGCGCCAGGTCATCGCCGGCATCGTCGGT
CCGGAGCGCACCCTGGTGCAAGAGCCGACCATGGGCGGGGAAGACTTTTCCTACATGCTGCAGGTCAAGCCGGGCGCCTA
CTGCTTCATTGGCAATGGCGATGGCGCCCACCGCGAGATGGGCCATGGCGGCGGGCCTTGCATGTTGCACAACCCGAGCT
ATGACTTCAACGACGAACTGATCCCGCTCGGCGCGACCTACTGGGTCAAACTGGCCCAGGAGTGGCTGGCCCGGCCGGCA
AGCAGCGGCGCCTGA

Upstream 100 bases:

>100_bases
TCTGCGGGAAATTTGATGCTCCGGCCCTGATGGGTAAACCCCCGGGCTGGCATATCTGCGGCCATCGGGCTAGACTGCGC
GACCGTTGAGGACAACTGCC

Downstream 100 bases:

>100_bases
GCCACCCCCGGTCCCGATCGGCACCCCGCAGGCGCGCAGCAAACGCCAACCGGGCGCGGAATCGGGCGTGCAATGCCCCC
TCGTTGCGGCCCGCAGGCCC

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNVIDSIVTQAASIAAVRRDIHAHPELCFEERRTADVVAQKLTEWGIPIHRGLGKTGVVGIVKGRDGGASGRAVGLRADI
DALPMQEFNSFAHASRHQGKMHACGHDGHTAMLLAAAQHFAQHRPFDGTVYLIFQPAEEGGGGARVMIEDGLFEQFPMQA
VFGMHNWPGMPVGSFAVSPGPVMASTSEFRITIRGKGGHAALPHTGIDPVPIACQMVQTFQTIISRNKKPVDAGVISVTM
VHAGEATNVVPDSCELRGTVRAFTIEVRDLIEKRMRQVAEHSCAAHGAVCEFEFVRNYPPTINSPAETEFVRQVIAGIVG
PERTLVQEPTMGGEDFSYMLQVKPGAYCFIGNGDGAHREMGHGGGPCMLHNPSYDFNDELIPLGATYWVKLAQEWLARPA
SSGA

Sequences:

>Translated_404_residues
MNVIDSIVTQAASIAAVRRDIHAHPELCFEERRTADVVAQKLTEWGIPIHRGLGKTGVVGIVKGRDGGASGRAVGLRADI
DALPMQEFNSFAHASRHQGKMHACGHDGHTAMLLAAAQHFAQHRPFDGTVYLIFQPAEEGGGGARVMIEDGLFEQFPMQA
VFGMHNWPGMPVGSFAVSPGPVMASTSEFRITIRGKGGHAALPHTGIDPVPIACQMVQTFQTIISRNKKPVDAGVISVTM
VHAGEATNVVPDSCELRGTVRAFTIEVRDLIEKRMRQVAEHSCAAHGAVCEFEFVRNYPPTINSPAETEFVRQVIAGIVG
PERTLVQEPTMGGEDFSYMLQVKPGAYCFIGNGDGAHREMGHGGGPCMLHNPSYDFNDELIPLGATYWVKLAQEWLARPA
SSGA
>Mature_404_residues
MNVIDSIVTQAASIAAVRRDIHAHPELCFEERRTADVVAQKLTEWGIPIHRGLGKTGVVGIVKGRDGGASGRAVGLRADI
DALPMQEFNSFAHASRHQGKMHACGHDGHTAMLLAAAQHFAQHRPFDGTVYLIFQPAEEGGGGARVMIEDGLFEQFPMQA
VFGMHNWPGMPVGSFAVSPGPVMASTSEFRITIRGKGGHAALPHTGIDPVPIACQMVQTFQTIISRNKKPVDAGVISVTM
VHAGEATNVVPDSCELRGTVRAFTIEVRDLIEKRMRQVAEHSCAAHGAVCEFEFVRNYPPTINSPAETEFVRQVIAGIVG
PERTLVQEPTMGGEDFSYMLQVKPGAYCFIGNGDGAHREMGHGGGPCMLHNPSYDFNDELIPLGATYWVKLAQEWLARPA
SSGA

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=450, Percent_Identity=26.6666666666667, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 43551; Mature: 43551

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIDSIVTQAASIAAVRRDIHAHPELCFEERRTADVVAQKLTEWGIPIHRGLGKTGVVG
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEE
IVKGRDGGASGRAVGLRADIDALPMQEFNSFAHASRHQGKMHACGHDGHTAMLLAAAQHF
EEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHH
AQHRPFDGTVYLIFQPAEEGGGGARVMIEDGLFEQFPMQAVFGMHNWPGMPVGSFAVSPG
HHCCCCCCEEEEEEEECCCCCCEEEEEEECCCHHHCCHHHHHCCCCCCCCCCCCEECCCC
PVMASTSEFRITIRGKGGHAALPHTGIDPVPIACQMVQTFQTIISRNKKPVDAGVISVTM
CCEECCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
VHAGEATNVVPDSCELRGTVRAFTIEVRDLIEKRMRQVAEHSCAAHGAVCEFEFVRNYPP
EECCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCC
TINSPAETEFVRQVIAGIVGPERTLVQEPTMGGEDFSYMLQVKPGAYCFIGNGDGAHREM
CCCCCHHHHHHHHHHHHHCCCCHHEECCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHC
GHGGGPCMLHNPSYDFNDELIPLGATYWVKLAQEWLARPASSGA
CCCCCCEEEECCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNVIDSIVTQAASIAAVRRDIHAHPELCFEERRTADVVAQKLTEWGIPIHRGLGKTGVVG
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEE
IVKGRDGGASGRAVGLRADIDALPMQEFNSFAHASRHQGKMHACGHDGHTAMLLAAAQHF
EEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHH
AQHRPFDGTVYLIFQPAEEGGGGARVMIEDGLFEQFPMQAVFGMHNWPGMPVGSFAVSPG
HHCCCCCCEEEEEEEECCCCCCEEEEEEECCCHHHCCHHHHHCCCCCCCCCCCCEECCCC
PVMASTSEFRITIRGKGGHAALPHTGIDPVPIACQMVQTFQTIISRNKKPVDAGVISVTM
CCEECCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
VHAGEATNVVPDSCELRGTVRAFTIEVRDLIEKRMRQVAEHSCAAHGAVCEFEFVRNYPP
EECCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCC
TINSPAETEFVRQVIAGIVGPERTLVQEPTMGGEDFSYMLQVKPGAYCFIGNGDGAHREM
CCCCCHHHHHHHHHHHHHCCCCHHEECCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHC
GHGGGPCMLHNPSYDFNDELIPLGATYWVKLAQEWLARPASSGA
CCCCCCEEEECCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]