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The map label for this gene is yofA [H]

Identifier: 121611651

GI number: 121611651

Start: 5237036

End: 5237977

Strand: Direct

Name: yofA [H]

Synonym: Veis_4745

Alternate gene names: 121611651

Gene position: 5237036-5237977 (Clockwise)

Preceding gene: 121611644

Following gene: 121611653

Centisome position: 94.08

GC content: 69.11

Gene sequence:

>942_bases
ATGAACACACGCTTTCTGGAGACGCTGGTCGTCCTTTCCCGCCTGAAGAGCTTTCGCGAGACGGCGCAGGTGCTGCACAC
CACGCAGGCGGCCGCATCGCAGCGCATCGCGGCGCTGGAAGACGAGCTAGGGGTTTTCCTTGTGGACCGCTCCCATCGCA
CCCTGACCCTCACGCCCGTCGGCGAGCAGGTGGTGCGGCAGGCCGAGCGCATGCTGGCGCTGGAACGCGAGCTCAAGCGC
GCGACGCAACCCGATGCGCCGCCCGCCGGGCGCGTGCGCATCGGCGTGATCGAGACCGTGGTCCACACCTGGCTCACGCC
GCTGATCCACGGGCTCACGCGCCGCTTTCCGGCGGTGGACCCGGACATCACCGTCGAGCCGGCGCGCAACCTGCGCGAGC
AGTTCCGCCAGCACAAGCTCGACCTCTTGATCCAGAACGACCCGGTCGAAGAAGCAGCCGGCAATGTGGAACTCGAAGTG
ACGCCGCTGTCGCGCTTTCCGATCCGCTGGATCGCGCGGCCCGATGTGTGGCGCACGCAGGACATGCTGACGCTGGAGGA
CCTGGAGCGCATTCCGGTGCTGACCTATGTGCGCACCTCCAGCCCGCATGCGCATGTGCGCGCGCTGTTCGCGGGCCGCG
AGACGGAACCGCGCATCTGTAGTTTCCCGTCGGTGCAGTCGATCGTGCAGCTCGTCAAGGAAGGCTTCGGCGTGGCGGCG
ATTCCGCCGATCTTCGTGCAGCGCGAGATCGAGGCCGGCGACCTGAAGCTCTGCGAGGGGCCCGCCCTGCCTGCGCTGGT
CGTGACGGTGACGCGGCCCCGGGAATCGTCGCCCGCCGTGGCGGCGATCGGCACCATCATCCGGCAGGTGGTGGGGAGCT
ACTGCAAGACGGCCGGCCCGCCGTGGGCCATCGACCTGCAGGCGGAGGCCGGGTCGGCCTGA

Upstream 100 bases:

>100_bases
CGATGAAATCACGGCACGCCGGTGGCGTCGACTCAGAAATTGTTCGCGCCCTCGATAAGATTTTTTTAAGAACCGCCTTG
CACCGAACACCGACGGACCG

Downstream 100 bases:

>100_bases
CCGGTCAGGCCGGACCAGATCAGGTCCAGCGGCCTTCCACCGGCTTTTTGCACCCGCTTCAGCACGCTGGAGAAGTCCAG
CGCACCATGGCCCGCTAGTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MNTRFLETLVVLSRLKSFRETAQVLHTTQAAASQRIAALEDELGVFLVDRSHRTLTLTPVGEQVVRQAERMLALERELKR
ATQPDAPPAGRVRIGVIETVVHTWLTPLIHGLTRRFPAVDPDITVEPARNLREQFRQHKLDLLIQNDPVEEAAGNVELEV
TPLSRFPIRWIARPDVWRTQDMLTLEDLERIPVLTYVRTSSPHAHVRALFAGRETEPRICSFPSVQSIVQLVKEGFGVAA
IPPIFVQREIEAGDLKLCEGPALPALVVTVTRPRESSPAVAAIGTIIRQVVGSYCKTAGPPWAIDLQAEAGSA

Sequences:

>Translated_313_residues
MNTRFLETLVVLSRLKSFRETAQVLHTTQAAASQRIAALEDELGVFLVDRSHRTLTLTPVGEQVVRQAERMLALERELKR
ATQPDAPPAGRVRIGVIETVVHTWLTPLIHGLTRRFPAVDPDITVEPARNLREQFRQHKLDLLIQNDPVEEAAGNVELEV
TPLSRFPIRWIARPDVWRTQDMLTLEDLERIPVLTYVRTSSPHAHVRALFAGRETEPRICSFPSVQSIVQLVKEGFGVAA
IPPIFVQREIEAGDLKLCEGPALPALVVTVTRPRESSPAVAAIGTIIRQVVGSYCKTAGPPWAIDLQAEAGSA
>Mature_313_residues
MNTRFLETLVVLSRLKSFRETAQVLHTTQAAASQRIAALEDELGVFLVDRSHRTLTLTPVGEQVVRQAERMLALERELKR
ATQPDAPPAGRVRIGVIETVVHTWLTPLIHGLTRRFPAVDPDITVEPARNLREQFRQHKLDLLIQNDPVEEAAGNVELEV
TPLSRFPIRWIARPDVWRTQDMLTLEDLERIPVLTYVRTSSPHAHVRALFAGRETEPRICSFPSVQSIVQLVKEGFGVAA
IPPIFVQREIEAGDLKLCEGPALPALVVTVTRPRESSPAVAAIGTIIRQVVGSYCKTAGPPWAIDLQAEAGSA

Specific function: Regulates expression of the cell division protein ftsW, and is essential for cell viability during stationary phase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790262, Length=244, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790399, Length=250, Percent_Identity=29.2, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786401, Length=246, Percent_Identity=28.8617886178862, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI157672245, Length=164, Percent_Identity=32.3170731707317, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787530, Length=231, Percent_Identity=24.2424242424242, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34716; Mature: 34716

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRFLETLVVLSRLKSFRETAQVLHTTQAAASQRIAALEDELGVFLVDRSHRTLTLTPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCC
GEQVVRQAERMLALERELKRATQPDAPPAGRVRIGVIETVVHTWLTPLIHGLTRRFPAVD
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDITVEPARNLREQFRQHKLDLLIQNDPVEEAAGNVELEVTPLSRFPIRWIARPDVWRTQ
CCCEECHHHHHHHHHHHHHHEEEECCCCHHHHCCCEEEEEEECCCCCEEEECCCCCCCCC
DMLTLEDLERIPVLTYVRTSSPHAHVRALFAGRETEPRICSFPSVQSIVQLVKEGFGVAA
CCHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
IPPIFVQREIEAGDLKLCEGPALPALVVTVTRPRESSPAVAAIGTIIRQVVGSYCKTAGP
CCHHHHEEECCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
PWAIDLQAEAGSA
CEEEEEECCCCCC
>Mature Secondary Structure
MNTRFLETLVVLSRLKSFRETAQVLHTTQAAASQRIAALEDELGVFLVDRSHRTLTLTPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCC
GEQVVRQAERMLALERELKRATQPDAPPAGRVRIGVIETVVHTWLTPLIHGLTRRFPAVD
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDITVEPARNLREQFRQHKLDLLIQNDPVEEAAGNVELEVTPLSRFPIRWIARPDVWRTQ
CCCEECHHHHHHHHHHHHHHEEEECCCCHHHHCCCEEEEEEECCCCCEEEECCCCCCCCC
DMLTLEDLERIPVLTYVRTSSPHAHVRALFAGRETEPRICSFPSVQSIVQLVKEGFGVAA
CCHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
IPPIFVQREIEAGDLKLCEGPALPALVVTVTRPRESSPAVAAIGTIIRQVVGSYCKTAGP
CCHHHHEEECCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
PWAIDLQAEAGSA
CEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]