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The map label for this gene is apbA [H]

Identifier: 121611563

GI number: 121611563

Start: 5147537

End: 5148457

Strand: Direct

Name: apbA [H]

Synonym: Veis_4655

Alternate gene names: 121611563

Gene position: 5147537-5148457 (Clockwise)

Preceding gene: 121611562

Following gene: 121611564

Centisome position: 92.47

GC content: 61.78

Gene sequence:

>921_bases
ATGAAAATCGCAATTGTGGGCTGCGGGGCGATGGGTTCCGTCTATGCGGGATTGCTGGCGTCCGCAGGGAACTCGTTATG
GATCGTGGATCGCTGGAAGGCACACGTGGAGGCGATCAACAGTCGGGGGTTGCGACTGGAAGGACCGCAGCGTGATCTCA
CGGCCTTCGCACACGCGTCGACGACAGCGCCTGACGAGCCGATGGACTTGGTCATCATCGCAGTCAAGGCCTCCGACGTG
GAAACTGGCGCTCAGCAAACGCTGTCAATGATCGGCCCCGAAACCATTGTCTTGACGATCCAGAACGGCCTTGGCAGCGC
TGATGCTGTGGCGCAAGTGGTGGGTGTTGACCGGCTTGCTGTCGGCATCGCCAGCGGATTTGGGGCATCCCTGAAAGGGC
CGGGGCACGCTCACCACAACGCGATGCAGGCGCTGCGCTTCGGTGCCTACTCAAGTCTTCCGTATGAGCGGGTCGTTGCC
GTGGCCCGCGTATGGGAAAGTGCGGGATTCGATGCGAAAGCAATCCGTGATATCGCTGTGATGCAGTGGGAGAAGCTCAT
CTGCAACGTCGCATACAGCGCGCCCTGTGCGTTGACGGGCATGACGGTCGGGGAGGTCATGAATGACCCGTGCATGGGGC
CGGTGAGTCAGGCCGCGGCGACTGAGGCGTGGAGCGTCGCCAGGGCGCTGGGAATTCAGATCGATGTGGACGACCCCGTG
GCGCATGTCAGGGCGTTCGGGGCACGGATGCCGGCCGCGAAGCCCTCGGCATTGCTGGATCACGAGGCGGGGCGCATCAG
TGAAATCGACGTCATCAATGGAGCCGTGCCGACGCAGGGCAACAAGCTGGGCATTGCGACGCCTGTCAACAGCACATTGA
CGCAGTTGGTGAGGGTCAAGGAACGTCAGTTTCGAAAGTAG

Upstream 100 bases:

>100_bases
TATGCCATGCCGACTCAGGCACCAGGCTTCGGCCTGGAGGAGAAGCCCGGGTTGAGCGAGGCCATCGCTGAACTGATCAA
GAGGTGAGGGGCAAGTCGTT

Downstream 100 bases:

>100_bases
CGCACCTATGAAGTCCTTCGTCCTTCACCGAGGTCTCGCGGTCCCGATGGCACGAGCCAACATCGACACGGATGCGATTC
TTCCGAAGCAATTCATGAAG

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKIAIVGCGAMGSVYAGLLASAGNSLWIVDRWKAHVEAINSRGLRLEGPQRDLTAFAHASTTAPDEPMDLVIIAVKASDV
ETGAQQTLSMIGPETIVLTIQNGLGSADAVAQVVGVDRLAVGIASGFGASLKGPGHAHHNAMQALRFGAYSSLPYERVVA
VARVWESAGFDAKAIRDIAVMQWEKLICNVAYSAPCALTGMTVGEVMNDPCMGPVSQAAATEAWSVARALGIQIDVDDPV
AHVRAFGARMPAAKPSALLDHEAGRISEIDVINGAVPTQGNKLGIATPVNSTLTQLVRVKERQFRK

Sequences:

>Translated_306_residues
MKIAIVGCGAMGSVYAGLLASAGNSLWIVDRWKAHVEAINSRGLRLEGPQRDLTAFAHASTTAPDEPMDLVIIAVKASDV
ETGAQQTLSMIGPETIVLTIQNGLGSADAVAQVVGVDRLAVGIASGFGASLKGPGHAHHNAMQALRFGAYSSLPYERVVA
VARVWESAGFDAKAIRDIAVMQWEKLICNVAYSAPCALTGMTVGEVMNDPCMGPVSQAAATEAWSVARALGIQIDVDDPV
AHVRAFGARMPAAKPSALLDHEAGRISEIDVINGAVPTQGNKLGIATPVNSTLTQLVRVKERQFRK
>Mature_306_residues
MKIAIVGCGAMGSVYAGLLASAGNSLWIVDRWKAHVEAINSRGLRLEGPQRDLTAFAHASTTAPDEPMDLVIIAVKASDV
ETGAQQTLSMIGPETIVLTIQNGLGSADAVAQVVGVDRLAVGIASGFGASLKGPGHAHHNAMQALRFGAYSSLPYERVVA
VARVWESAGFDAKAIRDIAVMQWEKLICNVAYSAPCALTGMTVGEVMNDPCMGPVSQAAATEAWSVARALGIQIDVDDPV
AHVRAFGARMPAAKPSALLDHEAGRISEIDVINGAVPTQGNKLGIATPVNSTLTQLVRVKERQFRK

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 32071; Mature: 32071

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIVGCGAMGSVYAGLLASAGNSLWIVDRWKAHVEAINSRGLRLEGPQRDLTAFAHAS
CEEEEEECCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEECCCHHHHHHHHHCC
TTAPDEPMDLVIIAVKASDVETGAQQTLSMIGPETIVLTIQNGLGSADAVAQVVGVDRLA
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
VGIASGFGASLKGPGHAHHNAMQALRFGAYSSLPYERVVAVARVWESAGFDAKAIRDIAV
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
MQWEKLICNVAYSAPCALTGMTVGEVMNDPCMGPVSQAAATEAWSVARALGIQIDVDDPV
HHHHHHHHHHHCCCCCCEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCHH
AHVRAFGARMPAAKPSALLDHEAGRISEIDVINGAVPTQGNKLGIATPVNSTLTQLVRVK
HHHHHHHHCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHH
ERQFRK
HHHHCC
>Mature Secondary Structure
MKIAIVGCGAMGSVYAGLLASAGNSLWIVDRWKAHVEAINSRGLRLEGPQRDLTAFAHAS
CEEEEEECCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEECCCHHHHHHHHHCC
TTAPDEPMDLVIIAVKASDVETGAQQTLSMIGPETIVLTIQNGLGSADAVAQVVGVDRLA
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
VGIASGFGASLKGPGHAHHNAMQALRFGAYSSLPYERVVAVARVWESAGFDAKAIRDIAV
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
MQWEKLICNVAYSAPCALTGMTVGEVMNDPCMGPVSQAAATEAWSVARALGIQIDVDDPV
HHHHHHHHHHHCCCCCCEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCHH
AHVRAFGARMPAAKPSALLDHEAGRISEIDVINGAVPTQGNKLGIATPVNSTLTQLVRVK
HHHHHHHHCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHH
ERQFRK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]