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The map label for this gene is kipI [H]

Identifier: 121611489

GI number: 121611489

Start: 5071164

End: 5072099

Strand: Direct

Name: kipI [H]

Synonym: Veis_4580

Alternate gene names: 121611489

Gene position: 5071164-5072099 (Clockwise)

Preceding gene: 121611488

Following gene: 121611490

Centisome position: 91.1

GC content: 65.71

Gene sequence:

>936_bases
ATGACCCCATCGACTCCATCGACTCCATCGACCCCCTCGACCCGATTGCCCCCGGCCCGCTACACCTTCGGCGGTGACGA
GCACCTGTTCGTCGAGATCAGCCAGGAGATGTCGCTGCCGGCCTTCTTCAAAGGGATGGCGCTGACCACTGCGTTGAGCC
AGCGCCGCATCGCCGGTGTCACCGAAGTCTGCCCGGCCAATGCCTCGTACCTGGTGCGCTTCGACCCGGACCAGATCGCG
CCGAACCGATTGCTCGAGGTGCTCGAAGGCATCGAAGCCACGGCCGACGCTGCCGACATGGCGCTCGATACCCGCATCAT
CGAGCTGCCGGTGCTCTACGACGACCCGTGGACCCATGAGTGCCTGATGCGTTTTCGCGAACGCCACCAAGACCCGGCCA
GCACCGACATCGAGTACGCCGCGCGGACCAACGGACACCGCAGCGTGGCGGACTTCATTGCCGCGCATTCGGGCGCGCCC
TGGTTCGTCTCCATGGTCGGCTTCGTCGCCGGGTTGCCGTTTCTGTTTCAGATGGTCGAACGCGAGCGCCAGATCGAAGT
GCCCAAGTACCTGCGCCCCCGAACCGACACGCCCCGGCTGACGCTGGGCCATGGCGGCTGTTTCGGCTGCGTGTATTCGG
TGCGCGGAGCCGGCGGCTATCAGATGTTTGGCGTCACGCCGGCGCCGATCTTCGATCCCGAGCGGCGGCTGGCCTATCTG
AAGGAGATGATGGTGTTCTTTCGCCCTGGCGACATCGTCAAGTGGCGCGCAATCACGCGCGCAGAGTACGAGCGCGACTG
CGCCGCCGTCGAGGCCGGCACGTTTGACCTGCGCATCCGGCCGGTGCGGTTTTCATTGCAGCGCTTTCTGGCCGACCCCG
ACGGCTACAACGCCGGCCTGATCGCCAGCCTGCGCAGCCAAGGAGCATCAGCATGA

Upstream 100 bases:

>100_bases
GCGCGACCCGCAGGTGCGCGCCGGGCAATTGCACACCGGCTTCCTGGAAGCCTGGCTCGCCGCCCATCCGATGTGAAACC
CCTTATCGCAGGATCAGGCC

Downstream 100 bases:

>100_bases
GCGCCGCACGGCCGCCCGAAGGCGAAGGTGCTCCCGTGGGCATCGAGGTCATCGAGCCGGGGCTGGCGACAACGGTGCAA
GACCTGGGGCGGCCGGGCTA

Product: allophanate hydrolase subunit 1

Products: NA

Alternate protein names: Sporulation inhibitor kipI [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTPSTPSTPSTPSTRLPPARYTFGGDEHLFVEISQEMSLPAFFKGMALTTALSQRRIAGVTEVCPANASYLVRFDPDQIA
PNRLLEVLEGIEATADAADMALDTRIIELPVLYDDPWTHECLMRFRERHQDPASTDIEYAARTNGHRSVADFIAAHSGAP
WFVSMVGFVAGLPFLFQMVERERQIEVPKYLRPRTDTPRLTLGHGGCFGCVYSVRGAGGYQMFGVTPAPIFDPERRLAYL
KEMMVFFRPGDIVKWRAITRAEYERDCAAVEAGTFDLRIRPVRFSLQRFLADPDGYNAGLIASLRSQGASA

Sequences:

>Translated_311_residues
MTPSTPSTPSTPSTRLPPARYTFGGDEHLFVEISQEMSLPAFFKGMALTTALSQRRIAGVTEVCPANASYLVRFDPDQIA
PNRLLEVLEGIEATADAADMALDTRIIELPVLYDDPWTHECLMRFRERHQDPASTDIEYAARTNGHRSVADFIAAHSGAP
WFVSMVGFVAGLPFLFQMVERERQIEVPKYLRPRTDTPRLTLGHGGCFGCVYSVRGAGGYQMFGVTPAPIFDPERRLAYL
KEMMVFFRPGDIVKWRAITRAEYERDCAAVEAGTFDLRIRPVRFSLQRFLADPDGYNAGLIASLRSQGASA
>Mature_310_residues
TPSTPSTPSTPSTRLPPARYTFGGDEHLFVEISQEMSLPAFFKGMALTTALSQRRIAGVTEVCPANASYLVRFDPDQIAP
NRLLEVLEGIEATADAADMALDTRIIELPVLYDDPWTHECLMRFRERHQDPASTDIEYAARTNGHRSVADFIAAHSGAPW
FVSMVGFVAGLPFLFQMVERERQIEVPKYLRPRTDTPRLTLGHGGCFGCVYSVRGAGGYQMFGVTPAPIFDPERRLAYLK
EMMVFFRPGDIVKWRAITRAEYERDCAAVEAGTFDLRIRPVRFSLQRFLADPDGYNAGLIASLRSQGASA

Specific function: Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase

COG id: COG2049

COG function: function code E; Allophanate hydrolase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Saccharomyces cerevisiae, GI6319685, Length=279, Percent_Identity=24.7311827956989, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003833
- InterPro:   IPR020899
- InterPro:   IPR010016
- InterPro:   IPR002130 [H]

Pfam domain/function: PF02682 AHS1 [H]

EC number: NA

Molecular weight: Translated: 34634; Mature: 34503

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSTPSTPSTPSTRLPPARYTFGGDEHLFVEISQEMSLPAFFKGMALTTALSQRRIAGV
CCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCH
TEVCPANASYLVRFDPDQIAPNRLLEVLEGIEATADAADMALDTRIIELPVLYDDPWTHE
HHHCCCCCEEEEEECCHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHH
CLMRFRERHQDPASTDIEYAARTNGHRSVADFIAAHSGAPWFVSMVGFVAGLPFLFQMVE
HHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RERQIEVPKYLRPRTDTPRLTLGHGGCFGCVYSVRGAGGYQMFGVTPAPIFDPERRLAYL
HHHCCCCCHHHCCCCCCCEEEECCCCHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHH
KEMMVFFRPGDIVKWRAITRAEYERDCAAVEAGTFDLRIRPVRFSLQRFLADPDGYNAGL
HHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCCCCCCCCHH
IASLRSQGASA
HHHHHHCCCCC
>Mature Secondary Structure 
TPSTPSTPSTPSTRLPPARYTFGGDEHLFVEISQEMSLPAFFKGMALTTALSQRRIAGV
CCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCH
TEVCPANASYLVRFDPDQIAPNRLLEVLEGIEATADAADMALDTRIIELPVLYDDPWTHE
HHHCCCCCEEEEEECCHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHH
CLMRFRERHQDPASTDIEYAARTNGHRSVADFIAAHSGAPWFVSMVGFVAGLPFLFQMVE
HHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RERQIEVPKYLRPRTDTPRLTLGHGGCFGCVYSVRGAGGYQMFGVTPAPIFDPERRLAYL
HHHCCCCCHHHCCCCCCCEEEECCCCHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHH
KEMMVFFRPGDIVKWRAITRAEYERDCAAVEAGTFDLRIRPVRFSLQRFLADPDGYNAGL
HHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCCCCCCCCHH
IASLRSQGASA
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]