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The map label for this gene is accB [H]

Identifier: 121611487

GI number: 121611487

Start: 5069520

End: 5069765

Strand: Direct

Name: accB [H]

Synonym: Veis_4578

Alternate gene names: 121611487

Gene position: 5069520-5069765 (Clockwise)

Preceding gene: 121611486

Following gene: 121611488

Centisome position: 91.07

GC content: 66.67

Gene sequence:

>246_bases
ATGCCGCAGATCGAAGTCCTGTCCCCGTTGCCCGGGATCTTCTACCGCCAGGCTGCGCCGGACGCGCCACCCTATGTCAC
CGAAGGCAGCCGCGTGCGCGTCGGCGATGTGCTCGGGCTGATCGAAGTGATGAAGCAGTTCAGCGAAGTGAGCGCCGAGG
TGGACGGCGCCGTGCTGCGCTTTGCCGTCGGCAACGGCGATGCGGTGGAGCCGGGCCAGACGCTGCTGTTCATCGAAACC
CCGTGA

Upstream 100 bases:

>100_bases
CCATCCGGGTCGCCGCCCTGCCGGAAGTTCTTCAAACCGCCTGAGCCGGCGACCACGGCGGCCCAGCGCGCCCCAAGCAA
CCACCACCGGAGCACCCACC

Downstream 100 bases:

>100_bases
GCGCGCAAGACCATGAAGCCGGCCTTTGACACCTTGCTGGTCGCCAATCGCGGCGAGATCGCCGTGCGCATCATCCGCGC
CGCGCGCGAGTTGGGCCTCA

Product: hypothetical protein

Products: Malonyl-CoA; malonyl-CoA; phosphate; ADP [C]

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 81; Mature: 80

Protein sequence:

>81_residues
MPQIEVLSPLPGIFYRQAAPDAPPYVTEGSRVRVGDVLGLIEVMKQFSEVSAEVDGAVLRFAVGNGDAVEPGQTLLFIET
P

Sequences:

>Translated_81_residues
MPQIEVLSPLPGIFYRQAAPDAPPYVTEGSRVRVGDVLGLIEVMKQFSEVSAEVDGAVLRFAVGNGDAVEPGQTLLFIET
P
>Mature_80_residues
PQIEVLSPLPGIFYRQAAPDAPPYVTEGSRVRVGDVLGLIEVMKQFSEVSAEVDGAVLRFAVGNGDAVEPGQTLLFIETP

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: NA

Molecular weight: Translated: 8657; Mature: 8526

Theoretical pI: Translated: 3.99; Mature: 3.99

Prosite motif: PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQIEVLSPLPGIFYRQAAPDAPPYVTEGSRVRVGDVLGLIEVMKQFSEVSAEVDGAVLR
CCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEEE
FAVGNGDAVEPGQTLLFIETP
EEECCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
PQIEVLSPLPGIFYRQAAPDAPPYVTEGSRVRVGDVLGLIEVMKQFSEVSAEVDGAVLR
CCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEEE
FAVGNGDAVEPGQTLLFIETP
EEECCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; HCO3-; Proton; acetyl-CoA; ATP [C]

Specific reaction: acetyl-CoA = malonyl-CoA HCO3- + Proton + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP [C]

General reaction: Ligases; Forming Carbon-Carbon Bonds; acetyl-CoA carboxylase Reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592499; 8969508; 9384377 [H]