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The map label for this gene is hslV

Identifier: 121611468

GI number: 121611468

Start: 5047423

End: 5047962

Strand: Direct

Name: hslV

Synonym: Veis_4559

Alternate gene names: 121611468

Gene position: 5047423-5047962 (Clockwise)

Preceding gene: 121611467

Following gene: 121611469

Centisome position: 90.67

GC content: 66.11

Gene sequence:

>540_bases
GTGTTTCACGGCACCACCATTTTGAGCGTGCGCCGCCAGACGCCCCAGGGCGTGCAGGTGGCCATTGGCGGCGATGGCCA
GGTCACGCTCGGCGCCATCGTCGTCAAGGGCACGGCCCGCAAGGTGCGCAAGCTGCACCACGGCAAGGTGCTGGCCGGTT
TCGCCGGCGCCACCGCCGATGCCTTCACGCTGTTCGAGCGCTTCGAGGCCAAGCTCGACAAGCACCAGGGCCACCTGGTG
CGCTCGGCCATCGAACTGACCAAGGACTGGCGCACCGACCGTGTGCTGCGCCGCCTCGAGGCCATGCTGGCCGTGGCCGA
TCAGGAGTCCTCGCTGATCATCACCGGCAATGGCGATGTGCTCGAACCCGAGCAGGGCATCATCGCGATTGGCTCGGGCG
GCGCCTATGCGAACGCCGCCGCCAAGGCCCTGCTCAACCACACCGATCTGAGCGCGGCGGACATCGTCAAGCAGGCGCTG
GAAATTGCGGGCGAACTGTGCATCTACACCAACATGCACCACACGATAGAAACGCTCTGA

Upstream 100 bases:

>100_bases
CCCGGTGCCGCAGGCGATTCAGGGGGGGTGTTGCGCACCAAGGCAAAATGCGGGGCCATTCCCATTTGCCGCTGTCATGG
ATTCATTGCAAAACCACCCG

Downstream 100 bases:

>100_bases
GTGCATTGCCGATCGGCGCCATCGGGTGCGCGCCGGGGGCCGCAAATTACTCTTTTTCTCATAGCTACAGGCGCCTGATT
CGTCTGCGCCTGTGCGTTGT

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MFHGTTILSVRRQTPQGVQVAIGGDGQVTLGAIVVKGTARKVRKLHHGKVLAGFAGATADAFTLFERFEAKLDKHQGHLV
RSAIELTKDWRTDRVLRRLEAMLAVADQESSLIITGNGDVLEPEQGIIAIGSGGAYANAAAKALLNHTDLSAADIVKQAL
EIAGELCIYTNMHHTIETL

Sequences:

>Translated_179_residues
MFHGTTILSVRRQTPQGVQVAIGGDGQVTLGAIVVKGTARKVRKLHHGKVLAGFAGATADAFTLFERFEAKLDKHQGHLV
RSAIELTKDWRTDRVLRRLEAMLAVADQESSLIITGNGDVLEPEQGIIAIGSGGAYANAAAKALLNHTDLSAADIVKQAL
EIAGELCIYTNMHHTIETL
>Mature_179_residues
MFHGTTILSVRRQTPQGVQVAIGGDGQVTLGAIVVKGTARKVRKLHHGKVLAGFAGATADAFTLFERFEAKLDKHQGHLV
RSAIELTKDWRTDRVLRRLEAMLAVADQESSLIITGNGDVLEPEQGIIAIGSGGAYANAAAKALLNHTDLSAADIVKQAL
EIAGELCIYTNMHHTIETL

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=175, Percent_Identity=66.2857142857143, Blast_Score=236, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_VEREI (A1WRK0)

Other databases:

- EMBL:   CP000542
- RefSeq:   YP_999275.1
- ProteinModelPortal:   A1WRK0
- SMR:   A1WRK0
- STRING:   A1WRK0
- MEROPS:   T01.006
- GeneID:   4694752
- GenomeReviews:   CP000542_GR
- KEGG:   vei:Veis_4559
- NMPDR:   fig|391735.5.peg.4179
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   A1WRK0
- ProtClustDB:   PRK05456
- BioCyc:   VEIS391735:VEIS_4559-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19159; Mature: 19159

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: ACT_SITE 5-5

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHGTTILSVRRQTPQGVQVAIGGDGQVTLGAIVVKGTARKVRKLHHGKVLAGFAGATAD
CCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEEEECCHHHHHHHHCCCEEEECCCCCHH
AFTLFERFEAKLDKHQGHLVRSAIELTKDWRTDRVLRRLEAMLAVADQESSLIITGNGDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCE
LEPEQGIIAIGSGGAYANAAAKALLNHTDLSAADIVKQALEIAGELCIYTNMHHTIETL
ECCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHCC
>Mature Secondary Structure
MFHGTTILSVRRQTPQGVQVAIGGDGQVTLGAIVVKGTARKVRKLHHGKVLAGFAGATAD
CCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEEEECCHHHHHHHHCCCEEEECCCCCHH
AFTLFERFEAKLDKHQGHLVRSAIELTKDWRTDRVLRRLEAMLAVADQESSLIITGNGDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCE
LEPEQGIIAIGSGGAYANAAAKALLNHTDLSAADIVKQALEIAGELCIYTNMHHTIETL
ECCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA