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The map label for this gene is codA [H]

Identifier: 121611344

GI number: 121611344

Start: 4880787

End: 4882061

Strand: Direct

Name: codA [H]

Synonym: Veis_4430

Alternate gene names: 121611344

Gene position: 4880787-4882061 (Clockwise)

Preceding gene: 121611343

Following gene: 121611351

Centisome position: 87.68

GC content: 69.96

Gene sequence:

>1275_bases
ATGCTCGACCTGCTGATCACCCACGCCAGCTTGCCCGACGGGCGCAGCGACATCTCCATCGCCGTGCAGGACGGCCGCAT
CAGCGCCGTCAGCGCCGGTCTGCAAGCCCCCGCGCATGAGCGCCTGGACGCCGGCGGCCTGCTGGTCAGCCCGCCGTTCG
TGGATGCGCATTTCCACCTGGACAGCGCGCTGACCTACGGCCAGCCACGGGTCAACGAGAGCGGCACGCTGCTCGAAGGC
ATTGCGCTGTGGGGCGAGCTCAAACCCCGGCTCCGGCATGAAAGCATCGTGCAGCGCGCGCTGCAATACTGCGACTGGGC
CGTGGCGCGCGGGCTGCTGGCGATTCGCTCGCATGTCGACTGCAGCCACCCCGACCTGCTGCCGGTGCACGCGCTGCTGG
AGGTGCGCCAGCGCGTCGCGCCGTATCTGGATTTGCAATTGGTGGCCTTCCCGCAAGACGGCGTGCTGCGCACCCCCGGC
GGGCTGGACAACCTCCAGCGCGCGCTGGCGCTGGGCGTGGACGTGGTCGGCGGCATTCCCCACTTCGAGCGCACCAGCGC
CCAGGGCAGCGAGAGCATCCGGCTGCTGTGCGGTTTGGCCGCCGCCCAAGGCAAGCGGGTGGACATGCACTGCGACGAGA
GCGACGACCCGCAGTCGCGCCATGTCGAAACCCTGGCCTTCGAGACCCGGCGCCTGGGCCTGCATGGCCGGGTGACAGGC
TCGCACCTGTGCTCGATGCACAGCATGGACAACTACTACGCGAGCCAACTGATCCCGCTGATGGCCGAGGCGCAACTGGG
CGTGGTCGCCAACCCGCTGGTCAACATCACGCTGCAAGGCCGCCACGACAGCTACCCCAAGCGCCGAGGCATGACCCGCG
TGCCCGAACTGATGGCCGCCGGCCTGACGGTGGCCTTTGGCCACGACTGCGTGCTCGACCCCTGGTACGGCGGCGGCAGC
GGCGACATGCTGGAGGCCGCCCACATGGGCCTGCACATCGCCCAGATGACCAGCCAGAGCGCGATGCGCCAATGCTTTGA
CGCCATCACCACCCACCCTGCCCGGCTGCTCGGCCTGCAAGACTATGGCCTGGCGCCCGGCTGCCATGCCGACCTGGTGC
TGCTGCATGCGCGCACCCCGGCGGAAGCCATCCGCCTGCGCGCAGCGCGCCTGGCGGTCTACCGGCGCGGCAAAAAAATC
GCCGGCAGCCCGGCACCGGTGGCCGCGCTGAACCTGCCGGGACGGCCCGGGCAGGTGGATTTTCTGGCGCGTTGA

Upstream 100 bases:

>100_bases
CGCACAGCGCCAGCGCAGGCCATGAAGAGCGCCCGCCAGTGCCGGCCAAAATCCCCTGCCAAAGCCCGATAGACCCCAAG
CCATACCAAAGGCCGCCACC

Downstream 100 bases:

>100_bases
GAACGCCCGGGAACCGGCCTGCGGCAGGTTCGGGCACGGCAGACCGGTTTTGCGCACAAGCCATCGATGTGCCATCACCA
CCGCGCCGGGACGCCGCGTG

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MLDLLITHASLPDGRSDISIAVQDGRISAVSAGLQAPAHERLDAGGLLVSPPFVDAHFHLDSALTYGQPRVNESGTLLEG
IALWGELKPRLRHESIVQRALQYCDWAVARGLLAIRSHVDCSHPDLLPVHALLEVRQRVAPYLDLQLVAFPQDGVLRTPG
GLDNLQRALALGVDVVGGIPHFERTSAQGSESIRLLCGLAAAQGKRVDMHCDESDDPQSRHVETLAFETRRLGLHGRVTG
SHLCSMHSMDNYYASQLIPLMAEAQLGVVANPLVNITLQGRHDSYPKRRGMTRVPELMAAGLTVAFGHDCVLDPWYGGGS
GDMLEAAHMGLHIAQMTSQSAMRQCFDAITTHPARLLGLQDYGLAPGCHADLVLLHARTPAEAIRLRAARLAVYRRGKKI
AGSPAPVAALNLPGRPGQVDFLAR

Sequences:

>Translated_424_residues
MLDLLITHASLPDGRSDISIAVQDGRISAVSAGLQAPAHERLDAGGLLVSPPFVDAHFHLDSALTYGQPRVNESGTLLEG
IALWGELKPRLRHESIVQRALQYCDWAVARGLLAIRSHVDCSHPDLLPVHALLEVRQRVAPYLDLQLVAFPQDGVLRTPG
GLDNLQRALALGVDVVGGIPHFERTSAQGSESIRLLCGLAAAQGKRVDMHCDESDDPQSRHVETLAFETRRLGLHGRVTG
SHLCSMHSMDNYYASQLIPLMAEAQLGVVANPLVNITLQGRHDSYPKRRGMTRVPELMAAGLTVAFGHDCVLDPWYGGGS
GDMLEAAHMGLHIAQMTSQSAMRQCFDAITTHPARLLGLQDYGLAPGCHADLVLLHARTPAEAIRLRAARLAVYRRGKKI
AGSPAPVAALNLPGRPGQVDFLAR
>Mature_424_residues
MLDLLITHASLPDGRSDISIAVQDGRISAVSAGLQAPAHERLDAGGLLVSPPFVDAHFHLDSALTYGQPRVNESGTLLEG
IALWGELKPRLRHESIVQRALQYCDWAVARGLLAIRSHVDCSHPDLLPVHALLEVRQRVAPYLDLQLVAFPQDGVLRTPG
GLDNLQRALALGVDVVGGIPHFERTSAQGSESIRLLCGLAAAQGKRVDMHCDESDDPQSRHVETLAFETRRLGLHGRVTG
SHLCSMHSMDNYYASQLIPLMAEAQLGVVANPLVNITLQGRHDSYPKRRGMTRVPELMAAGLTVAFGHDCVLDPWYGGGS
GDMLEAAHMGLHIAQMTSQSAMRQCFDAITTHPARLLGLQDYGLAPGCHADLVLLHARTPAEAIRLRAARLAVYRRGKKI
AGSPAPVAALNLPGRPGQVDFLAR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=418, Percent_Identity=46.1722488038278, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI1786517, Length=409, Percent_Identity=27.1393643031785, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 45763; Mature: 45763

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLLITHASLPDGRSDISIAVQDGRISAVSAGLQAPAHERLDAGGLLVSPPFVDAHFHL
CCEEEEEECCCCCCCCCEEEEEECCCEEEHHHCCCCCCHHHCCCCCEEECCCCEEEEEEE
DSALTYGQPRVNESGTLLEGIALWGELKPRLRHESIVQRALQYCDWAVARGLLAIRSHVD
CCHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
CSHPDLLPVHALLEVRQRVAPYLDLQLVAFPQDGVLRTPGGLDNLQRALALGVDVVGGIP
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCC
HFERTSAQGSESIRLLCGLAAAQGKRVDMHCDESDDPQSRHVETLAFETRRLGLHGRVTG
CCCCCCCCCCCCEEHEEEHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
SHLCSMHSMDNYYASQLIPLMAEAQLGVVANPLVNITLQGRHDSYPKRRGMTRVPELMAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GLTVAFGHDCVLDPWYGGGSGDMLEAAHMGLHIAQMTSQSAMRQCFDAITTHPARLLGLQ
CCEEEECCCEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHEEECH
DYGLAPGCHADLVLLHARTPAEAIRLRAARLAVYRRGKKIAGSPAPVAALNLPGRPGQVD
HCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCC
FLAR
CCCC
>Mature Secondary Structure
MLDLLITHASLPDGRSDISIAVQDGRISAVSAGLQAPAHERLDAGGLLVSPPFVDAHFHL
CCEEEEEECCCCCCCCCEEEEEECCCEEEHHHCCCCCCHHHCCCCCEEECCCCEEEEEEE
DSALTYGQPRVNESGTLLEGIALWGELKPRLRHESIVQRALQYCDWAVARGLLAIRSHVD
CCHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
CSHPDLLPVHALLEVRQRVAPYLDLQLVAFPQDGVLRTPGGLDNLQRALALGVDVVGGIP
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCC
HFERTSAQGSESIRLLCGLAAAQGKRVDMHCDESDDPQSRHVETLAFETRRLGLHGRVTG
CCCCCCCCCCCCEEHEEEHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
SHLCSMHSMDNYYASQLIPLMAEAQLGVVANPLVNITLQGRHDSYPKRRGMTRVPELMAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GLTVAFGHDCVLDPWYGGGSGDMLEAAHMGLHIAQMTSQSAMRQCFDAITTHPARLLGLQ
CCEEEECCCEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHEEECH
DYGLAPGCHADLVLLHARTPAEAIRLRAARLAVYRRGKKIAGSPAPVAALNLPGRPGQVD
HCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCC
FLAR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]