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The map label for this gene is rbsC [H]

Identifier: 121611240

GI number: 121611240

Start: 4766146

End: 4767219

Strand: Direct

Name: rbsC [H]

Synonym: Veis_4326

Alternate gene names: 121611240

Gene position: 4766146-4767219 (Clockwise)

Preceding gene: 121611229

Following gene: 121611241

Centisome position: 85.62

GC content: 68.81

Gene sequence:

>1074_bases
ATGAAACGGCTTCCGGGCGACGCCCAGCTCAACGTTCTGGCGGCCATCAACGCGGCGGTGGTGCTGTGCGCCATTGCGCT
CACCGGCGGCGGTTTCATCGATCCCTACAACCTGCAATCGATGGCGGGCCAGGTGCCCGAATTGGGGCTGCTGGCCATTG
GCGTGATGCTGGCCATGATCGCCGGCAACGGCGGCATCGACCTGTCGGGCATCGCGCTGGCCAACCTGGCCGGCGTGTGC
GCCGGCGTGCTGCTGCCGCACTGGGTCGACGCCGGGCAGACGCCGCTGCTGTTCACCCTGGCATTGGTGGGCGTGGCGCT
GGCGGTCGGGCTGCTGGGCGGGCTGCTCAACGGCCTGCTGATCGCCTGCGCCGGGCTGACGCCCACTCTCTGCACGCTGG
GCACGCAGTTGGTGTTCGCCGGGCTGGCGGTGGTGCTGTCCGGCGGCTCGGCGGTGCGCATCGGCCTCATCGAGCCGCTG
GACTTCATCGGCAACGGACTGGTGCTGGGCCTGCCGCTGTGCTTCATGCTGTTCGTCGGCATCGCGCTGGCCATCGGCGT
GTGGCTGCGCCACAGCCCCTTCGGCATGCGACTGTTCCTGATGGGCACCAACCCCAAGGCGGCGCGCTACGCCGGCGTGC
CGCAGCGGCGCATGCTGCTGTCGGTGTACACGCTGTGCGGCCTGCTGGCCTCGGTGTCCGGCATCGTGATCGCGGCGCGC
AGTTCCAGCGTGAAGTGGGACTACGGCAGTTCCTATGTGCTGATCGCCATCCTGATCGCGGTGATGGCCGGCGTGCGGCC
CGAGGGTGGCCACGGCCGGATGCTGTGCCTGCTGCTGTCGGCCACGGCGTTGCAGTTCCTGTCGAGCACCTTCAACTTCC
TGGAGGTGTCGAGCTTCTTTCGCGACTGCGCATGGGGGCTGATGCTCTTGCTGTTCGTCGCATCGTCCCGCTTCGACGCG
CGCTCGCTGCTGCCGCTGCGCCTGCGTCATGCCGTTGCCGCGCAGTCCCCTCCTGCGGCGCGGTTCAATTCCGGGGGGCT
TGCGCCAGCAAGGCAGGAGGAAACCGCACCATGA

Upstream 100 bases:

>100_bases
CCCACTCTGGCAGAACCAGCATGGACAGACCGTGGAACGCTGCCGACGCCGCGCATTTCGCGGCCCGGCACGCAGCGCGC
CAGTTGAAGACGGGGCGCCA

Downstream 100 bases:

>100_bases
TCCGTCACACCGCATGCACGCTCGCCGCCGTGGCCTGTATCGCCGGCGCCGCGTGGGCGCAGGACAAGCAGAGCATCGTG
ACCGTGGTCAAGGTCATCGG

Product: inner-membrane translocator

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKRLPGDAQLNVLAAINAAVVLCAIALTGGGFIDPYNLQSMAGQVPELGLLAIGVMLAMIAGNGGIDLSGIALANLAGVC
AGVLLPHWVDAGQTPLLFTLALVGVALAVGLLGGLLNGLLIACAGLTPTLCTLGTQLVFAGLAVVLSGGSAVRIGLIEPL
DFIGNGLVLGLPLCFMLFVGIALAIGVWLRHSPFGMRLFLMGTNPKAARYAGVPQRRMLLSVYTLCGLLASVSGIVIAAR
SSSVKWDYGSSYVLIAILIAVMAGVRPEGGHGRMLCLLLSATALQFLSSTFNFLEVSSFFRDCAWGLMLLLFVASSRFDA
RSLLPLRLRHAVAAQSPPAARFNSGGLAPARQEETAP

Sequences:

>Translated_357_residues
MKRLPGDAQLNVLAAINAAVVLCAIALTGGGFIDPYNLQSMAGQVPELGLLAIGVMLAMIAGNGGIDLSGIALANLAGVC
AGVLLPHWVDAGQTPLLFTLALVGVALAVGLLGGLLNGLLIACAGLTPTLCTLGTQLVFAGLAVVLSGGSAVRIGLIEPL
DFIGNGLVLGLPLCFMLFVGIALAIGVWLRHSPFGMRLFLMGTNPKAARYAGVPQRRMLLSVYTLCGLLASVSGIVIAAR
SSSVKWDYGSSYVLIAILIAVMAGVRPEGGHGRMLCLLLSATALQFLSSTFNFLEVSSFFRDCAWGLMLLLFVASSRFDA
RSLLPLRLRHAVAAQSPPAARFNSGGLAPARQEETAP
>Mature_357_residues
MKRLPGDAQLNVLAAINAAVVLCAIALTGGGFIDPYNLQSMAGQVPELGLLAIGVMLAMIAGNGGIDLSGIALANLAGVC
AGVLLPHWVDAGQTPLLFTLALVGVALAVGLLGGLLNGLLIACAGLTPTLCTLGTQLVFAGLAVVLSGGSAVRIGLIEPL
DFIGNGLVLGLPLCFMLFVGIALAIGVWLRHSPFGMRLFLMGTNPKAARYAGVPQRRMLLSVYTLCGLLASVSGIVIAAR
SSSVKWDYGSSYVLIAILIAVMAGVRPEGGHGRMLCLLLSATALQFLSSTFNFLEVSSFFRDCAWGLMLLLFVASSRFDA
RSLLPLRLRHAVAAQSPPAARFNSGGLAPARQEETAP

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=316, Percent_Identity=29.746835443038, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI145693152, Length=308, Percent_Identity=30.1948051948052, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787794, Length=165, Percent_Identity=32.7272727272727, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790524, Length=290, Percent_Identity=25.5172413793103, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788896, Length=297, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788471, Length=204, Percent_Identity=32.843137254902, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 36893; Mature: 36893

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLPGDAQLNVLAAINAAVVLCAIALTGGGFIDPYNLQSMAGQVPELGLLAIGVMLAMI
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHH
AGNGGIDLSGIALANLAGVCAGVLLPHWVDAGQTPLLFTLALVGVALAVGLLGGLLNGLL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IACAGLTPTLCTLGTQLVFAGLAVVLSGGSAVRIGLIEPLDFIGNGLVLGLPLCFMLFVG
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHHH
IALAIGVWLRHSPFGMRLFLMGTNPKAARYAGVPQRRMLLSVYTLCGLLASVSGIVIAAR
HHHHHHHHHHCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEC
SSSVKWDYGSSYVLIAILIAVMAGVRPEGGHGRMLCLLLSATALQFLSSTFNFLEVSSFF
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDCAWGLMLLLFVASSRFDARSLLPLRLRHAVAAQSPPAARFNSGGLAPARQEETAP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRLPGDAQLNVLAAINAAVVLCAIALTGGGFIDPYNLQSMAGQVPELGLLAIGVMLAMI
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHH
AGNGGIDLSGIALANLAGVCAGVLLPHWVDAGQTPLLFTLALVGVALAVGLLGGLLNGLL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IACAGLTPTLCTLGTQLVFAGLAVVLSGGSAVRIGLIEPLDFIGNGLVLGLPLCFMLFVG
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHHH
IALAIGVWLRHSPFGMRLFLMGTNPKAARYAGVPQRRMLLSVYTLCGLLASVSGIVIAAR
HHHHHHHHHHCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEC
SSSVKWDYGSSYVLIAILIAVMAGVRPEGGHGRMLCLLLSATALQFLSSTFNFLEVSSFF
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDCAWGLMLLLFVASSRFDARSLLPLRLRHAVAAQSPPAARFNSGGLAPARQEETAP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]