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The map label for this gene is acdA [H]

Identifier: 121611102

GI number: 121611102

Start: 4608690

End: 4609856

Strand: Direct

Name: acdA [H]

Synonym: Veis_4186

Alternate gene names: 121611102

Gene position: 4608690-4609856 (Clockwise)

Preceding gene: 121611101

Following gene: 121611103

Centisome position: 82.79

GC content: 65.12

Gene sequence:

>1167_bases
ATGCTGACTCCTGAACACATCGCCCTCCAAGACAGCGTTCGCCAGTTCATCGCGCGCGAGATCACGCCGCACATCGACGA
ATGGGAAGCCGCCGAAATCTTTCCCGCGCACGACATCTTCAAGAAGCTCGGCAACGCCGGTTTCCTCGGCGTGAACAAGC
CCGTGGAGTTCGGCGGCATGGGCCTGGACTACTCCTACGAGATCGCCTTCTGCGAGGCCATCGGCGGCATCGGCGCCGGT
GGCGTGGGCATGGCCATCGCGGTGCAGACCGACATGGCCACGCCGGCACTCGCGCGCTTCGGCTCCGACGAGCTGCGCGA
GCGCTTCCTCAAGCCCACGGTGGCGGGCGACTACGTGGTGTGCCTGGGCGTCTCCGAAGCCGGCGCCGGCTCCGACGTGG
CCTCGGTGAAGACCACGGCGCGCAAGGACGGCGACGACTACGTGATCAACGGCTCCAAGATGTGGATCACCAATGGCTTG
CAGGCCGACTGGATGTGCCTGCTGGCCAACACCGGCGGCGAGGACCCGCACCGCAACAAGTCGTTGATCTGCCTGCCGCT
GCGCGAGAACGGCAAGCTGCGCCCCGGCATCACGATGAACAAGATCAAGAAGGTCGGCATGTGGTCGTCCGACACCGCGC
AGGTGTTCTTCGACGACGTACGCGTGCCGCAGCGCTACCGCATTGGCGAAGAAGGCAAGGGCTTCATCTACCAGATGAAG
CAGTTCCAGGAAGAACGCCTGAGCGGCGCCACGCGGCGCGTTACCGCGCTGATGAACGTGGTGCACGAGACCATCGACTA
CACACGCCAGCGCAAGGCCTTCGGCCAATCGATCCTGGACAACCAGGTGGTGCATTTCCGCATGGCCGAGCTCAAGACCG
AGATCGAACTGCTGCGCTCGCTGATCTACCGGGCCGCGCAGGTCCACATGGCCGATGGCGACATGACCGAGCTGGCCTCG
ATGGCCAAGCTCAAGGCCGGCCGGCTGTGCCGCGAGGTCACCGACTCGTGCCTGCAGTACTGGGGCGGCATGGGCTTCAC
CTGGGACAACTCCGTCTCGCGCGCCTGGCGCGACCTGCGGCTCATCTCCATTGGCGGCGGCGCCGACGAAATCATGCTCA
CCATCATCTGCAAGCACATGGGCATCCTGCCCAAGCGCGCCGCCTGA

Upstream 100 bases:

>100_bases
GAGCGGCACGCCCTTTCGCTACGACTGGGAGCGGCCACACTGAACGGCCGCCCTCTACCTTCCTTCTTTTCATCCACCCT
TTTTCTTCTGCCTCACGACC

Downstream 100 bases:

>100_bases
CCATGCGCTTCGACACCCTGCTGATTGCCAACCGCGGCGAGATCGCCCTGCGCGTCATGCGCACCGCGCGCCGCATGGGC
CTGCGCACCGTCGCGGTGTA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MLTPEHIALQDSVRQFIAREITPHIDEWEAAEIFPAHDIFKKLGNAGFLGVNKPVEFGGMGLDYSYEIAFCEAIGGIGAG
GVGMAIAVQTDMATPALARFGSDELRERFLKPTVAGDYVVCLGVSEAGAGSDVASVKTTARKDGDDYVINGSKMWITNGL
QADWMCLLANTGGEDPHRNKSLICLPLRENGKLRPGITMNKIKKVGMWSSDTAQVFFDDVRVPQRYRIGEEGKGFIYQMK
QFQEERLSGATRRVTALMNVVHETIDYTRQRKAFGQSILDNQVVHFRMAELKTEIELLRSLIYRAAQVHMADGDMTELAS
MAKLKAGRLCREVTDSCLQYWGGMGFTWDNSVSRAWRDLRLISIGGGADEIMLTIICKHMGILPKRAA

Sequences:

>Translated_388_residues
MLTPEHIALQDSVRQFIAREITPHIDEWEAAEIFPAHDIFKKLGNAGFLGVNKPVEFGGMGLDYSYEIAFCEAIGGIGAG
GVGMAIAVQTDMATPALARFGSDELRERFLKPTVAGDYVVCLGVSEAGAGSDVASVKTTARKDGDDYVINGSKMWITNGL
QADWMCLLANTGGEDPHRNKSLICLPLRENGKLRPGITMNKIKKVGMWSSDTAQVFFDDVRVPQRYRIGEEGKGFIYQMK
QFQEERLSGATRRVTALMNVVHETIDYTRQRKAFGQSILDNQVVHFRMAELKTEIELLRSLIYRAAQVHMADGDMTELAS
MAKLKAGRLCREVTDSCLQYWGGMGFTWDNSVSRAWRDLRLISIGGGADEIMLTIICKHMGILPKRAA
>Mature_388_residues
MLTPEHIALQDSVRQFIAREITPHIDEWEAAEIFPAHDIFKKLGNAGFLGVNKPVEFGGMGLDYSYEIAFCEAIGGIGAG
GVGMAIAVQTDMATPALARFGSDELRERFLKPTVAGDYVVCLGVSEAGAGSDVASVKTTARKDGDDYVINGSKMWITNGL
QADWMCLLANTGGEDPHRNKSLICLPLRENGKLRPGITMNKIKKVGMWSSDTAQVFFDDVRVPQRYRIGEEGKGFIYQMK
QFQEERLSGATRRVTALMNVVHETIDYTRQRKAFGQSILDNQVVHFRMAELKTEIELLRSLIYRAAQVHMADGDMTELAS
MAKLKAGRLCREVTDSCLQYWGGMGFTWDNSVSRAWRDLRLISIGGGADEIMLTIICKHMGILPKRAA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=382, Percent_Identity=36.1256544502618, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI4557233, Length=380, Percent_Identity=32.3684210526316, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI7656849, Length=382, Percent_Identity=32.7225130890052, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=30.2387267904509, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI4501859, Length=383, Percent_Identity=30.0261096605744, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=31.3782991202346, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI4557231, Length=381, Percent_Identity=29.9212598425197, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI187960098, Length=381, Percent_Identity=29.9212598425197, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI4557235, Length=341, Percent_Identity=30.4985337243402, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI76496475, Length=336, Percent_Identity=30.952380952381, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI21361497, Length=343, Percent_Identity=26.2390670553936, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI38505218, Length=296, Percent_Identity=26.6891891891892, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI211971008, Length=412, Percent_Identity=26.4563106796117, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI48976061, Length=412, Percent_Identity=26.4563106796117, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4503943, Length=390, Percent_Identity=23.3333333333333, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI7669494, Length=377, Percent_Identity=23.342175066313, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=31.5649867374005, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786223, Length=381, Percent_Identity=27.2965879265092, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=51.3368983957219, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=51.3368983957219, Blast_Score=383, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17538396, Length=383, Percent_Identity=32.1148825065274, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17508101, Length=382, Percent_Identity=30.3664921465969, Blast_Score=191, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17570075, Length=380, Percent_Identity=31.8421052631579, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17506239, Length=383, Percent_Identity=29.242819843342, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI17534899, Length=373, Percent_Identity=31.6353887399464, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71990804, Length=282, Percent_Identity=35.1063829787234, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17569725, Length=389, Percent_Identity=29.305912596401, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17533517, Length=372, Percent_Identity=29.0322580645161, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32563615, Length=238, Percent_Identity=31.0924369747899, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI71985184, Length=364, Percent_Identity=25.2747252747253, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=28.1021897810219, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71985192, Length=270, Percent_Identity=25.1851851851852, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17531909, Length=246, Percent_Identity=28.0487804878049, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17534353, Length=389, Percent_Identity=24.1645244215938, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562446, Length=297, Percent_Identity=24.2424242424242, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531913, Length=174, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=31.8302387267904, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=30.1587301587302, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=30.6068601583113, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=31.0704960835509, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24660351, Length=389, Percent_Identity=31.3624678663239, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI281363737, Length=339, Percent_Identity=29.7935103244838, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI19920834, Length=309, Percent_Identity=27.1844660194175, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42966; Mature: 42966

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPEHIALQDSVRQFIAREITPHIDEWEAAEIFPAHDIFKKLGNAGFLGVNKPVEFGGM
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHCCCCEEECCCCCCCCCC
GLDYSYEIAFCEAIGGIGAGGVGMAIAVQTDMATPALARFGSDELRERFLKPTVAGDYVV
CCCCEEEEEHHHHHCCCCCCCCCEEEEEECCCCCHHHHHCCCHHHHHHHCCCCCCCCEEE
CLGVSEAGAGSDVASVKTTARKDGDDYVINGSKMWITNGLQADWMCLLANTGGEDPHRNK
EEECCCCCCCCCHHHHHHHHCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCC
SLICLPLRENGKLRPGITMNKIKKVGMWSSDTAQVFFDDVRVPQRYRIGEEGKGFIYQMK
CEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCHHHCCCCCCCHHHHHHH
QFQEERLSGATRRVTALMNVVHETIDYTRQRKAFGQSILDNQVVHFRMAELKTEIELLRS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LIYRAAQVHMADGDMTELASMAKLKAGRLCREVTDSCLQYWGGMGFTWDNSVSRAWRDLR
HHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEE
LISIGGGADEIMLTIICKHMGILPKRAA
EEEECCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLTPEHIALQDSVRQFIAREITPHIDEWEAAEIFPAHDIFKKLGNAGFLGVNKPVEFGGM
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHCCCCEEECCCCCCCCCC
GLDYSYEIAFCEAIGGIGAGGVGMAIAVQTDMATPALARFGSDELRERFLKPTVAGDYVV
CCCCEEEEEHHHHHCCCCCCCCCEEEEEECCCCCHHHHHCCCHHHHHHHCCCCCCCCEEE
CLGVSEAGAGSDVASVKTTARKDGDDYVINGSKMWITNGLQADWMCLLANTGGEDPHRNK
EEECCCCCCCCCHHHHHHHHCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCC
SLICLPLRENGKLRPGITMNKIKKVGMWSSDTAQVFFDDVRVPQRYRIGEEGKGFIYQMK
CEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCHHHCCCCCCCHHHHHHH
QFQEERLSGATRRVTALMNVVHETIDYTRQRKAFGQSILDNQVVHFRMAELKTEIELLRS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LIYRAAQVHMADGDMTELASMAKLKAGRLCREVTDSCLQYWGGMGFTWDNSVSRAWRDLR
HHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEE
LISIGGGADEIMLTIICKHMGILPKRAA
EEEECCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]