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The map label for this gene is ruvB

Identifier: 121610986

GI number: 121610986

Start: 4463756

End: 4464820

Strand: Direct

Name: ruvB

Synonym: Veis_4070

Alternate gene names: 121610986

Gene position: 4463756-4464820 (Clockwise)

Preceding gene: 121610985

Following gene: 121610987

Centisome position: 80.19

GC content: 67.42

Gene sequence:

>1065_bases
ATGACCCTGCAAACCGACGACTTCGCCCCTGCTCCCGCCCGGCGCGTTGTCTCTGCGGCGCCCGCTTCGCCCCAGGAGCA
GGCGATCGAGCGGGCGCTGCGTCCCAAGCTGCTGCAGGAGTACGTGGGCCAGGTCAAGGCGCGCGAGCAGTTGGAAATCT
TCATCGGCGCAGCGCGCCAGCGCGGCGAAGCCCTCGACCATGTGCTGTTGTTCGGCCCGCCCGGCCTGGGCAAAACCACG
CTCAGCCACATCATTGCCGCAGAACTGGGCGTGAACCTGCGCCAGACCAGCGGACCGGTGCTGGAAAAGCCCAAGGACCT
GGCGGCGCTGCTGACCAACCTGGAAAATCGGGATGTCCTGTTCATCGATGAGATCCACCGCCTGTCGCCCGTGGTCGAGG
AAATCCTCTACCCGGCGCTGGAGGACTACCAGATCGACATCATGATCGGCGAAGGCCCTGCGGCGCGCAGCATCAAGCTC
GACCTGCAGCCCTTCACCCTGGTCGGTGCGACCACGCGCGCCGGCATGCTGACCAATCCGCTGCGCGACCGCTTCGGCAT
CGTGGCCCGGCTGGAGTTCTACAGCGCGCAAGAACTGGCGCGCATCGTCAAGCGCAGCGCCGGCCTGCTCGGTGTCCCGA
TGGATGACGCCGGGGGTCTGGAGATCGCCCGCCGCTCGCGCGGCACGCCGCGCATCGCCAACCGGCTGCTGCGGCGCGTG
CGCGACTACACCCAGGTCAAGGCCGACGGCCACATCACCAAGGACATTGCCGAGCGCGCCCTGGCCATGCTCGACGTAGA
CCCCGAGGGCCTGGACGTGATGGACCGCAAACTGCTCGAAGCCGTGATCCACCGCTTCGACGGCGGCCCCGTCGGGCTGG
ACAACATCGCCGCCAGCATTGGCGAAGAAACCGGCACCATCGAAGACGTGATCGAGCCCTATCTGATACAGCAGGGTTTC
TTGCAGCGCACACCGCGCGGACGCATCGCCACGCAGGCCGCCTTCCGGCACCTGGGGATCGCCGCAGCGCCTGGCGCGCA
AGCGCCAGGCTTGTTTGCTGTCTGA

Upstream 100 bases:

>100_bases
CCATCAACCAGGCCGAGCGGGACTTCATCATCGCCCACTATCGTGAGTACACCTACGAGGGCCCCAACTACTACGCGTGG
ACCAATCCATAAGCCCTGCG

Downstream 100 bases:

>100_bases
ACGAGACGGCATCTGCAAACACGGGCACTGAGCCATGCCGGCCGGGGCGCTGGCACTGATACCATCACCTCCTGCGGCAC
CACCGCTGATCCGCTGATCC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTLQTDDFAPAPARRVVSAAPASPQEQAIERALRPKLLQEYVGQVKAREQLEIFIGAARQRGEALDHVLLFGPPGLGKTT
LSHIIAAELGVNLRQTSGPVLEKPKDLAALLTNLENRDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKL
DLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYSAQELARIVKRSAGLLGVPMDDAGGLEIARRSRGTPRIANRLLRRV
RDYTQVKADGHITKDIAERALAMLDVDPEGLDVMDRKLLEAVIHRFDGGPVGLDNIAASIGEETGTIEDVIEPYLIQQGF
LQRTPRGRIATQAAFRHLGIAAAPGAQAPGLFAV

Sequences:

>Translated_354_residues
MTLQTDDFAPAPARRVVSAAPASPQEQAIERALRPKLLQEYVGQVKAREQLEIFIGAARQRGEALDHVLLFGPPGLGKTT
LSHIIAAELGVNLRQTSGPVLEKPKDLAALLTNLENRDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKL
DLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYSAQELARIVKRSAGLLGVPMDDAGGLEIARRSRGTPRIANRLLRRV
RDYTQVKADGHITKDIAERALAMLDVDPEGLDVMDRKLLEAVIHRFDGGPVGLDNIAASIGEETGTIEDVIEPYLIQQGF
LQRTPRGRIATQAAFRHLGIAAAPGAQAPGLFAV
>Mature_353_residues
TLQTDDFAPAPARRVVSAAPASPQEQAIERALRPKLLQEYVGQVKAREQLEIFIGAARQRGEALDHVLLFGPPGLGKTTL
SHIIAAELGVNLRQTSGPVLEKPKDLAALLTNLENRDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKLD
LQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYSAQELARIVKRSAGLLGVPMDDAGGLEIARRSRGTPRIANRLLRRVR
DYTQVKADGHITKDIAERALAMLDVDPEGLDVMDRKLLEAVIHRFDGGPVGLDNIAASIGEETGTIEDVIEPYLIQQGFL
QRTPRGRIATQAAFRHLGIAAAPGAQAPGLFAV

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=329, Percent_Identity=72.0364741641337, Blast_Score=473, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_VEREI (A1WQ68)

Other databases:

- EMBL:   CP000542
- RefSeq:   YP_998793.1
- ProteinModelPortal:   A1WQ68
- SMR:   A1WQ68
- STRING:   A1WQ68
- GeneID:   4693778
- GenomeReviews:   CP000542_GR
- KEGG:   vei:Veis_4070
- NMPDR:   fig|391735.5.peg.3725
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   A1WQ68
- ProtClustDB:   PRK00080
- BioCyc:   VEIS391735:VEIS_4070-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38554; Mature: 38423

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQTDDFAPAPARRVVSAAPASPQEQAIERALRPKLLQEYVGQVKAREQLEIFIGAARQ
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGEALDHVLLFGPPGLGKTTLSHIIAAELGVNLRQTSGPVLEKPKDLAALLTNLENRDVL
HHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHCCCCCCEE
FIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKLDLQPFTLVGATTRAGMLTNP
EHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHHHHH
LRDRFGIVARLEFYSAQELARIVKRSAGLLGVPMDDAGGLEIARRSRGTPRIANRLLRRV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHH
RDYTQVKADGHITKDIAERALAMLDVDPEGLDVMDRKLLEAVIHRFDGGPVGLDNIAASI
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GEETGTIEDVIEPYLIQQGFLQRTPRGRIATQAAFRHLGIAAAPGAQAPGLFAV
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCC
>Mature Secondary Structure 
TLQTDDFAPAPARRVVSAAPASPQEQAIERALRPKLLQEYVGQVKAREQLEIFIGAARQ
CCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGEALDHVLLFGPPGLGKTTLSHIIAAELGVNLRQTSGPVLEKPKDLAALLTNLENRDVL
HHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHCCCCCCEE
FIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKLDLQPFTLVGATTRAGMLTNP
EHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHHHHH
LRDRFGIVARLEFYSAQELARIVKRSAGLLGVPMDDAGGLEIARRSRGTPRIANRLLRRV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHH
RDYTQVKADGHITKDIAERALAMLDVDPEGLDVMDRKLLEAVIHRFDGGPVGLDNIAASI
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GEETGTIEDVIEPYLIQQGFLQRTPRGRIATQAAFRHLGIAAAPGAQAPGLFAV
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA