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The map label for this gene is prpL [H]

Identifier: 121610985

GI number: 121610985

Start: 4461831

End: 4463747

Strand: Direct

Name: prpL [H]

Synonym: Veis_4069

Alternate gene names: 121610985

Gene position: 4461831-4463747 (Clockwise)

Preceding gene: 121610984

Following gene: 121610986

Centisome position: 80.15

GC content: 64.06

Gene sequence:

>1917_bases
ATGAAAAATCCCGGGTTTGTGGCCCGCATGGGCATGCTGGGCGCCTTGGCGACCGTCCTCCTGTCTGGCTGTGGCGGCGC
GGGCCAGGACGGCGCCCCATCGGCCGCCCAGACCCCGTCGGTAGCGAAGGTGGAGCAGGTGGACGGCCGGGTGCAGCCCG
CCAGCGCCGACCAGGGTGTGCCGCATGTCAAGTCGCGCCATGTGGGCGCAATCCCGATTCCGTCCCGGATCCGTCTGGGC
GCGTTGAAGCAGGAGGAAATCCGGTCCGCCGTCTCTGACGCAAGCCCCCGCAAATTGGTCGGCCTGGCCCGCGCCGTGGA
CGCCGCGCCGACCTTGCAGCAACTGCAATGGCAGCCTGTGGCCGGCGGCGGCCAGGTCGCCGCCATCAGCGTTTCTGCCG
AAGGCGCCCATGGCCTGCGGCTGGGGATCGTCGTGCGGCAGTTGCCCGGCAGTGCCGTGCTGCGCCTGTATCGCCAGGCC
GCGCCCGCCACGGTGTTCCAGATCTCGGGCCAGGAGGTGCTGCAGCGCATCGAGAGCAACGCGCTGGCCGGCGACCGCAG
CCTCGACGGCCAGACCTGGTGGACGCCGGATCTGGGCGCCGACGAGGTCACGCTGGAGTTGGAACTGCCCGCAGGCGCCG
ACGTGGCTGCGCTCGACATGGCGCTGACCCGCGTATCGCATATCTTCGAGAACCTGGCCCTGCCCACGCAGGAGGAGTTC
GAGACCAAGATCAACGATGCCATGCCATGCAACCGGGACGCCAGTTGCGAGAATGACTATGCCGACCAGCGCAACGCCGT
GGCACGCACGAGCTTCGTATCGCGGGGCGATGCCTATACGTGCACCGGCACCTTGCTCAACGACAGCCAATCTTCGGGGA
CACCGTATTTCCTGAGCGCCCACCACTGCATTTCGTCGCAGGCCGAGGCGGACACGCTGGAGACGAACTGGTTCTACCGC
TCGTCCTCATGCCGCAGCCGCACGCTGTCGAGCCGCTCTGTCCACCGCCGGGGCGGCGCCAAGCTGCTGTATTCCTCGGC
CAGCACCGACACCGCGCTGCTCCAGCTCAATGACGCACCGCCCGAAGGGGCCTTCTTTGCCGGCTGGGATGCCAGCGCCC
AGGCCAAGTATTCTTCGGTGGCGACGCTGCACCACCCGGCTGGCGACATGCTGAAGATCAGTTTGGGCCGTTTGGGAGAG
CAGACCACCTGCACCGCGATGAGCCAGTCAGGGTCGTTCGACTGCGAAGGAAAGACGGGCAACTATTACGAGGTGTACTG
GTACCGGGGAACGACCGAGTACGGAAGCAGCGGCGCGGCCCTGCTCAATAGCGCCAAAAAGGTGATCGGCACCTTGTACG
GCGGCACCTCCAGTTGTTTCAACATGTCTGCGAAAGAGATCTTTGGCCGGTTCGACGTGGCCTATGAGGCCGGACTGAAA
AAATGGCTGGCAGCAGCGCCGGCCGACGCATCGAACCAGCGCGTTGCAGTCCATCGCTTCTACAACAACAGAGCAGGCTC
GCATTTCTTCACCACCAATGTGGCCGAGCGGGACTACGTGATCCAGAGATTGTCCGACTTTGCGTATGAAGGGGTGGCCT
TTTACGCACAAGCACAGGCTCAGCCGGGCAGCATCCCCATGTACCGTTTCTATGGCGCGGACAGTGGCGCCCATTTCTTC
ACGGCCAGCGCGCAAGAGCGCGACGATGTGAAAAACAATATGCCGCAATACCGCTACGAGGGCATTGCATGGTACGCATC
GCCTGACCACAGCGCCAACACATCACCGGTATTCCGCTTCTCCTACAAGCAGGTACCCTTCTACACCATCAACCAGGCCG
AGCGGGACTTCATCATCGCCCACTATCGTGAGTACACCTACGAGGGCCCCAACTACTACGCGTGGACCAATCCATAA

Upstream 100 bases:

>100_bases
CAAGGCCTTGACGAAGTAGCATCCGGACGCTTGCGTGCCGTCTTGTCACATGCTTGGCACACTGCGAACATCCAACCACC
TTACTGAGTGAGGACGAGAA

Downstream 100 bases:

>100_bases
GCCCTGCGATGACCCTGCAAACCGACGACTTCGCCCCTGCTCCCGCCCGGCGCGTTGTCTCTGCGGCGCCCGCTTCGCCC
CAGGAGCAGGCGATCGAGCG

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: Protease IV; pvdS-regulated endoprotease [H]

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MKNPGFVARMGMLGALATVLLSGCGGAGQDGAPSAAQTPSVAKVEQVDGRVQPASADQGVPHVKSRHVGAIPIPSRIRLG
ALKQEEIRSAVSDASPRKLVGLARAVDAAPTLQQLQWQPVAGGGQVAAISVSAEGAHGLRLGIVVRQLPGSAVLRLYRQA
APATVFQISGQEVLQRIESNALAGDRSLDGQTWWTPDLGADEVTLELELPAGADVAALDMALTRVSHIFENLALPTQEEF
ETKINDAMPCNRDASCENDYADQRNAVARTSFVSRGDAYTCTGTLLNDSQSSGTPYFLSAHHCISSQAEADTLETNWFYR
SSSCRSRTLSSRSVHRRGGAKLLYSSASTDTALLQLNDAPPEGAFFAGWDASAQAKYSSVATLHHPAGDMLKISLGRLGE
QTTCTAMSQSGSFDCEGKTGNYYEVYWYRGTTEYGSSGAALLNSAKKVIGTLYGGTSSCFNMSAKEIFGRFDVAYEAGLK
KWLAAAPADASNQRVAVHRFYNNRAGSHFFTTNVAERDYVIQRLSDFAYEGVAFYAQAQAQPGSIPMYRFYGADSGAHFF
TASAQERDDVKNNMPQYRYEGIAWYASPDHSANTSPVFRFSYKQVPFYTINQAERDFIIAHYREYTYEGPNYYAWTNP

Sequences:

>Translated_638_residues
MKNPGFVARMGMLGALATVLLSGCGGAGQDGAPSAAQTPSVAKVEQVDGRVQPASADQGVPHVKSRHVGAIPIPSRIRLG
ALKQEEIRSAVSDASPRKLVGLARAVDAAPTLQQLQWQPVAGGGQVAAISVSAEGAHGLRLGIVVRQLPGSAVLRLYRQA
APATVFQISGQEVLQRIESNALAGDRSLDGQTWWTPDLGADEVTLELELPAGADVAALDMALTRVSHIFENLALPTQEEF
ETKINDAMPCNRDASCENDYADQRNAVARTSFVSRGDAYTCTGTLLNDSQSSGTPYFLSAHHCISSQAEADTLETNWFYR
SSSCRSRTLSSRSVHRRGGAKLLYSSASTDTALLQLNDAPPEGAFFAGWDASAQAKYSSVATLHHPAGDMLKISLGRLGE
QTTCTAMSQSGSFDCEGKTGNYYEVYWYRGTTEYGSSGAALLNSAKKVIGTLYGGTSSCFNMSAKEIFGRFDVAYEAGLK
KWLAAAPADASNQRVAVHRFYNNRAGSHFFTTNVAERDYVIQRLSDFAYEGVAFYAQAQAQPGSIPMYRFYGADSGAHFF
TASAQERDDVKNNMPQYRYEGIAWYASPDHSANTSPVFRFSYKQVPFYTINQAERDFIIAHYREYTYEGPNYYAWTNP
>Mature_638_residues
MKNPGFVARMGMLGALATVLLSGCGGAGQDGAPSAAQTPSVAKVEQVDGRVQPASADQGVPHVKSRHVGAIPIPSRIRLG
ALKQEEIRSAVSDASPRKLVGLARAVDAAPTLQQLQWQPVAGGGQVAAISVSAEGAHGLRLGIVVRQLPGSAVLRLYRQA
APATVFQISGQEVLQRIESNALAGDRSLDGQTWWTPDLGADEVTLELELPAGADVAALDMALTRVSHIFENLALPTQEEF
ETKINDAMPCNRDASCENDYADQRNAVARTSFVSRGDAYTCTGTLLNDSQSSGTPYFLSAHHCISSQAEADTLETNWFYR
SSSCRSRTLSSRSVHRRGGAKLLYSSASTDTALLQLNDAPPEGAFFAGWDASAQAKYSSVATLHHPAGDMLKISLGRLGE
QTTCTAMSQSGSFDCEGKTGNYYEVYWYRGTTEYGSSGAALLNSAKKVIGTLYGGTSSCFNMSAKEIFGRFDVAYEAGLK
KWLAAAPADASNQRVAVHRFYNNRAGSHFFTTNVAERDYVIQRLSDFAYEGVAFYAQAQAQPGSIPMYRFYGADSGAHFF
TASAQERDDVKNNMPQYRYEGIAWYASPDHSANTSPVFRFSYKQVPFYTINQAERDFIIAHYREYTYEGPNYYAWTNP

Specific function: Lysine-specific endoprotease. Involved in corneal virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003 [H]

Pfam domain/function: NA

EC number: =3.4.21.50 [H]

Molecular weight: Translated: 69115; Mature: 69115

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNPGFVARMGMLGALATVLLSGCGGAGQDGAPSAAQTPSVAKVEQVDGRVQPASADQGV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCC
PHVKSRHVGAIPIPSRIRLGALKQEEIRSAVSDASPRKLVGLARAVDAAPTLQQLQWQPV
CCHHCCCCCCCCCCCCCEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCEEEEC
AGGGQVAAISVSAEGAHGLRLGIVVRQLPGSAVLRLYRQAAPATVFQISGQEVLQRIESN
CCCCEEEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHC
ALAGDRSLDGQTWWTPDLGADEVTLELELPAGADVAALDMALTRVSHIFENLALPTQEEF
CCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
ETKINDAMPCNRDASCENDYADQRNAVARTSFVSRGDAYTCTGTLLNDSQSSGTPYFLSA
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEEH
HHCISSQAEADTLETNWFYRSSSCRSRTLSSRSVHRRGGAKLLYSSASTDTALLQLNDAP
HHHHCCCCCCCEEECCEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCC
PEGAFFAGWDASAQAKYSSVATLHHPAGDMLKISLGRLGEQTTCTAMSQSGSFDCEGKTG
CCCCEEECCCCCCCCHHHHEEEEECCCCCEEEEEHHHCCCCCEEEEECCCCCEEECCCCC
NYYEVYWYRGTTEYGSSGAALLNSAKKVIGTLYGGTSSCFNMSAKEIFGRFDVAYEAGLK
CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHH
KWLAAAPADASNQRVAVHRFYNNRAGSHFFTTNVAERDYVIQRLSDFAYEGVAFYAQAQA
HHHHCCCCCCCCCEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCC
QPGSIPMYRFYGADSGAHFFTASAQERDDVKNNMPQYRYEGIAWYASPDHSANTSPVFRF
CCCCCCEEEEECCCCCCEEEEECCHHHHHHHHCCCCEEECCEEEEECCCCCCCCCCEEEE
SYKQVPFYTINQAERDFIIAHYREYTYEGPNYYAWTNP
EECCCCEEEECCCCCCEEEEEEHHHCCCCCCEEEECCC
>Mature Secondary Structure
MKNPGFVARMGMLGALATVLLSGCGGAGQDGAPSAAQTPSVAKVEQVDGRVQPASADQGV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCC
PHVKSRHVGAIPIPSRIRLGALKQEEIRSAVSDASPRKLVGLARAVDAAPTLQQLQWQPV
CCHHCCCCCCCCCCCCCEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCEEEEC
AGGGQVAAISVSAEGAHGLRLGIVVRQLPGSAVLRLYRQAAPATVFQISGQEVLQRIESN
CCCCEEEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHC
ALAGDRSLDGQTWWTPDLGADEVTLELELPAGADVAALDMALTRVSHIFENLALPTQEEF
CCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
ETKINDAMPCNRDASCENDYADQRNAVARTSFVSRGDAYTCTGTLLNDSQSSGTPYFLSA
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEEH
HHCISSQAEADTLETNWFYRSSSCRSRTLSSRSVHRRGGAKLLYSSASTDTALLQLNDAP
HHHHCCCCCCCEEECCEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCC
PEGAFFAGWDASAQAKYSSVATLHHPAGDMLKISLGRLGEQTTCTAMSQSGSFDCEGKTG
CCCCEEECCCCCCCCHHHHEEEEECCCCCEEEEEHHHCCCCCEEEEECCCCCEEECCCCC
NYYEVYWYRGTTEYGSSGAALLNSAKKVIGTLYGGTSSCFNMSAKEIFGRFDVAYEAGLK
CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHH
KWLAAAPADASNQRVAVHRFYNNRAGSHFFTTNVAERDYVIQRLSDFAYEGVAFYAQAQA
HHHHCCCCCCCCCEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCC
QPGSIPMYRFYGADSGAHFFTASAQERDDVKNNMPQYRYEGIAWYASPDHSANTSPVFRF
CCCCCCEEEEECCCCCCEEEEECCHHHHHHHHCCCCEEECCEEEEECCCCCCCCCCEEEE
SYKQVPFYTINQAERDFIIAHYREYTYEGPNYYAWTNP
EECCCCEEEECCCCCCEEEEEEHHHCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12419815; 10984043 [H]