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The map label for this gene is soxB [H]

Identifier: 121610962

GI number: 121610962

Start: 4435635

End: 4437008

Strand: Direct

Name: soxB [H]

Synonym: Veis_4046

Alternate gene names: 121610962

Gene position: 4435635-4437008 (Clockwise)

Preceding gene: 121610954

Following gene: 121610963

Centisome position: 79.68

GC content: 67.61

Gene sequence:

>1374_bases
GTGTGCGTCTGTCAGACGCAAGCCTGCGCAGCACAGGCAGAGACAATGCAAGCGGATTCGCCGGCCCCCTTACTCCACGA
TTGCCCACGATCCCCACGAGATCACATGCGACCAATGCGCGGCCAAAATTACTCGCTCTGGAGCCTGTTCAAGCATGGCC
TGGGCCACCATCTGCGCTGGGAGCCGGCCTGGGAGCGGGTGGCGCTCAAGCCGGACTACGACGTGGTGATCGTCGGCGGC
GGCGGACATGGCCTGGCGACGGCCTACTACCTGGCCAAGAACCACCCGACGGTGGGCCGCATCGCGGTGCTGGAAAAGGG
CTATCTGGGCGGCGGCAACACGGCGCGCAACACCACCATCGTGCGCTCGAACTATCTGTGGGACGAGGCGGCGCAGCTCT
ACGAGCACTCGCTCAAGCTGTGGGAGGGCTTGAGCCAGGAACTGAACATGAATGTGATGTTCAGCCAGCGCGGCGTGTTC
AACCTGGGCCATACGCTGCAAGACATGCGCGACATCGAGCGCAGGGTCAACGCCAACGCGCTGCAAGGCATCGATGCCCA
GGTGCTCAGCGCCAGCGAGGTGCAGCAAAAAATCCCGCAACTCGATTGCAGCCGCAGCCGCCGCTACCCGGTGCTGGGCG
CCAGTTGGCAGCCGCGCGCCGGGGTGGCGCACCACGATGCGGTGGCGCGCGGCTTCGCCCGTGCCGCAAGCCGGCTGGGG
GTGGACCTGATCGAGGGCTGCGAGGTCACCGGCATGGACATCGAGGGCGGGCGGATCCGCGCGCTGCAAACCAGCCTCGG
GCCGGTCAAGGCCGAGCGCGTCGGTTGCGTGGCCGCCGGGCATTCGTCGGAGCTGGCCCGCATGGCCGGGCTGCGCCTGC
CGCTGCAAAGCCATCCGCTGCAAGCCTTTGTCTCGGAGTCGATGCAGCCCGTGATCGACACCGTGATCATGTCCAACGCC
GTGCATGGCTACCTGAGCCAGTCCGACAAGGGCGAACTGGTGATAGGCGCCGGCATCGACGGCTATCTGGGCTACGGCCA
GCGCGGCAGCCCGCATGTCATCGAGCACACGGCGGCGGCCATCATCGAGCTGTTTCCGCAGTTCTCGCGCGTGCGCATGA
ACCGCCAATGGGGCGGCATCGTCGATGTGGCGCCGGACGCCTGCCCGATCATTTCCGCGACCGCAGTGCAGGGCCTGTAC
TTCAACTGCGGCTGGGGCACCGGCGGCTTCAAGGCCACGCCCGGCTCGGGCCATGTCTTTGCCGACATGCTGGCGCATGG
CCGTCCGCCCCCGCTGGCCCAAGCCTTCGCGCTGGAGCGCTTCGCCTCCGGCCACCTGATCGACGAGCACGGCGCCGCCG
GCGTCGCCCACTGA

Upstream 100 bases:

>100_bases
GCAAGGCGGCATGCGCCAGACCTGCCCGGCGGTCATCGTGGGCAACGCTGCGGCCCGGCGGATACCGGATGCGGTGCGGC
GGCATGTCGGGTTTGAACAA

Downstream 100 bases:

>100_bases
ATATGTTTTTATTGCATTGCCCCCACTGCGGCGAGTTGCGCGACGAACAAGAGTTCGGCTACGCCGGCGAAGCCTTCATT
GCCCGCCCGGCCCAGCCCGA

Product: sarcosine oxidase subunit beta family protein

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MCVCQTQACAAQAETMQADSPAPLLHDCPRSPRDHMRPMRGQNYSLWSLFKHGLGHHLRWEPAWERVALKPDYDVVIVGG
GGHGLATAYYLAKNHPTVGRIAVLEKGYLGGGNTARNTTIVRSNYLWDEAAQLYEHSLKLWEGLSQELNMNVMFSQRGVF
NLGHTLQDMRDIERRVNANALQGIDAQVLSASEVQQKIPQLDCSRSRRYPVLGASWQPRAGVAHHDAVARGFARAASRLG
VDLIEGCEVTGMDIEGGRIRALQTSLGPVKAERVGCVAAGHSSELARMAGLRLPLQSHPLQAFVSESMQPVIDTVIMSNA
VHGYLSQSDKGELVIGAGIDGYLGYGQRGSPHVIEHTAAAIIELFPQFSRVRMNRQWGGIVDVAPDACPIISATAVQGLY
FNCGWGTGGFKATPGSGHVFADMLAHGRPPPLAQAFALERFASGHLIDEHGAAGVAH

Sequences:

>Translated_457_residues
MCVCQTQACAAQAETMQADSPAPLLHDCPRSPRDHMRPMRGQNYSLWSLFKHGLGHHLRWEPAWERVALKPDYDVVIVGG
GGHGLATAYYLAKNHPTVGRIAVLEKGYLGGGNTARNTTIVRSNYLWDEAAQLYEHSLKLWEGLSQELNMNVMFSQRGVF
NLGHTLQDMRDIERRVNANALQGIDAQVLSASEVQQKIPQLDCSRSRRYPVLGASWQPRAGVAHHDAVARGFARAASRLG
VDLIEGCEVTGMDIEGGRIRALQTSLGPVKAERVGCVAAGHSSELARMAGLRLPLQSHPLQAFVSESMQPVIDTVIMSNA
VHGYLSQSDKGELVIGAGIDGYLGYGQRGSPHVIEHTAAAIIELFPQFSRVRMNRQWGGIVDVAPDACPIISATAVQGLY
FNCGWGTGGFKATPGSGHVFADMLAHGRPPPLAQAFALERFASGHLIDEHGAAGVAH
>Mature_457_residues
MCVCQTQACAAQAETMQADSPAPLLHDCPRSPRDHMRPMRGQNYSLWSLFKHGLGHHLRWEPAWERVALKPDYDVVIVGG
GGHGLATAYYLAKNHPTVGRIAVLEKGYLGGGNTARNTTIVRSNYLWDEAAQLYEHSLKLWEGLSQELNMNVMFSQRGVF
NLGHTLQDMRDIERRVNANALQGIDAQVLSASEVQQKIPQLDCSRSRRYPVLGASWQPRAGVAHHDAVARGFARAASRLG
VDLIEGCEVTGMDIEGGRIRALQTSLGPVKAERVGCVAAGHSSELARMAGLRLPLQSHPLQAFVSESMQPVIDTVIMSNA
VHGYLSQSDKGELVIGAGIDGYLGYGQRGSPHVIEHTAAAIIELFPQFSRVRMNRQWGGIVDVAPDACPIISATAVQGLY
FNCGWGTGGFKATPGSGHVFADMLAHGRPPPLAQAFALERFASGHLIDEHGAAGVAH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=389, Percent_Identity=22.6221079691517, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI21361378, Length=389, Percent_Identity=22.6221079691517, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI24797151, Length=380, Percent_Identity=22.1052631578947, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI60499001, Length=246, Percent_Identity=25.609756097561, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI194306651, Length=395, Percent_Identity=23.0379746835443, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1787438, Length=319, Percent_Identity=21.6300940438871, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130091, Length=387, Percent_Identity=25.3229974160207, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28571104, Length=390, Percent_Identity=22.3076923076923, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 49424; Mature: 49424

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVCQTQACAAQAETMQADSPAPLLHDCPRSPRDHMRPMRGQNYSLWSLFKHGLGHHLRW
CCEECCHHHHHHHHHHCCCCCCCHHHHCCCCCHHHCCCCCCCCCHHHHHHHHCCCCCCCC
EPAWERVALKPDYDVVIVGGGGHGLATAYYLAKNHPTVGRIAVLEKGYLGGGNTARNTTI
CCCHHEEEECCCCCEEEECCCCCCHHHEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEE
VRSNYLWDEAAQLYEHSLKLWEGLSQELNMNVMFSQRGVFNLGHTLQDMRDIERRVNANA
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHH
LQGIDAQVLSASEVQQKIPQLDCSRSRRYPVLGASWQPRAGVAHHDAVARGFARAASRLG
HCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
VDLIEGCEVTGMDIEGGRIRALQTSLGPVKAERVGCVAAGHSSELARMAGLRLPLQSHPL
CHHHCCCCEEEEECCCCEEEEEECCCCCCHHHHEEEEECCCHHHHHHHHCCCCCCCCCCH
QAFVSESMQPVIDTVIMSNAVHGYLSQSDKGELVIGAGIDGYLGYGQRGSPHVIEHTAAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
IIELFPQFSRVRMNRQWGGIVDVAPDACPIISATAVQGLYFNCGWGTGGFKATPGSGHVF
HHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHCCEEEECCCCCCCCCCCCCCCCHH
ADMLAHGRPPPLAQAFALERFASGHLIDEHGAAGVAH
HHHHHCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCC
>Mature Secondary Structure
MCVCQTQACAAQAETMQADSPAPLLHDCPRSPRDHMRPMRGQNYSLWSLFKHGLGHHLRW
CCEECCHHHHHHHHHHCCCCCCCHHHHCCCCCHHHCCCCCCCCCHHHHHHHHCCCCCCCC
EPAWERVALKPDYDVVIVGGGGHGLATAYYLAKNHPTVGRIAVLEKGYLGGGNTARNTTI
CCCHHEEEECCCCCEEEECCCCCCHHHEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEE
VRSNYLWDEAAQLYEHSLKLWEGLSQELNMNVMFSQRGVFNLGHTLQDMRDIERRVNANA
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHH
LQGIDAQVLSASEVQQKIPQLDCSRSRRYPVLGASWQPRAGVAHHDAVARGFARAASRLG
HCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
VDLIEGCEVTGMDIEGGRIRALQTSLGPVKAERVGCVAAGHSSELARMAGLRLPLQSHPL
CHHHCCCCEEEEECCCCEEEEEECCCCCCHHHHEEEEECCCHHHHHHHHCCCCCCCCCCH
QAFVSESMQPVIDTVIMSNAVHGYLSQSDKGELVIGAGIDGYLGYGQRGSPHVIEHTAAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
IIELFPQFSRVRMNRQWGGIVDVAPDACPIISATAVQGLYFNCGWGTGGFKATPGSGHVF
HHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHCCEEEECCCCCCCCCCCCCCCCHH
ADMLAHGRPPPLAQAFALERFASGHLIDEHGAAGVAH
HHHHHCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]