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The map label for this gene is coaE [H]

Identifier: 121610840

GI number: 121610840

Start: 4310376

End: 4311008

Strand: Direct

Name: coaE [H]

Synonym: Veis_3922

Alternate gene names: 121610840

Gene position: 4310376-4311008 (Clockwise)

Preceding gene: 121610839

Following gene: 121610841

Centisome position: 77.43

GC content: 69.04

Gene sequence:

>633_bases
ATGCGCCGCAAGCCATCGCGTCCATTGCGTGTGGGCCTGACCGGCGGCATTGGCAGCGGCAAGAGCACGGTGGGGCAGAT
GCTGGCGGCCCTGGGGGCCTGCCTGATCGACGCGGACCAAATTTCCCGTGAAGTGACGGGGCCGCAGGGCGCCGCGATGG
CGGCCATACGCAGCACTTTCGGCGCCGAGTATGTCGACGCCTGCGGTGCGCTCGACCGTGCACGCATGCGGCAGTTGGCG
TTCAGTCAGCCGCAGGCGCGTGCACGCCTGGAGGGCATCATTCATCCCCTGGTCGCTGCCCATGGCGATTCGCGGGCGCA
GCAGGCGCTGGCAGCGGGGGCCGGGTTGATCGTGCATGACATTCCTTTGCTGGCCGAGTCCGGACCATCCGGGCCATGGG
CGCGCCGCCTCGATGCCGTGGTGGTGGTCGACTGCCTGGCCGAGACCCAGATCGAGCGCGTGATGCGCCGCAGCGGCCTG
GCACGCGAGCAGGTGCAGGGCATCATTGCGTCACAGGCCAGCCGCAGCGCGCGCAGGGCGCTGGCCGATGTGGTGCTTGC
CAATGAGGCCGATGGCACGCTGCAACAGCTACAGGCCGAGGTCCGGCAGATGGCTCGTTGGTTCGGGCTATGA

Upstream 100 bases:

>100_bases
CCCCTTCGGGCCTTTTCTGGTCGGCGCCGGTCTGACGGCGCTGGTGTTCGGCCCCGGCACCATGCTGGGCCTGGCGCTCG
GGCTGCTGGGCCTTTGATCC

Downstream 100 bases:

>100_bases
TGCGGCCCCGTAGCCGGTTGGTACTTTCAACTTCCCCAGCAGCGTGATCCTTTACGAATATCCTTTCAACGAGCGTCTGA
GAACTTATTTGCGGCTCGAG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MRRKPSRPLRVGLTGGIGSGKSTVGQMLAALGACLIDADQISREVTGPQGAAMAAIRSTFGAEYVDACGALDRARMRQLA
FSQPQARARLEGIIHPLVAAHGDSRAQQALAAGAGLIVHDIPLLAESGPSGPWARRLDAVVVVDCLAETQIERVMRRSGL
AREQVQGIIASQASRSARRALADVVLANEADGTLQQLQAEVRQMARWFGL

Sequences:

>Translated_210_residues
MRRKPSRPLRVGLTGGIGSGKSTVGQMLAALGACLIDADQISREVTGPQGAAMAAIRSTFGAEYVDACGALDRARMRQLA
FSQPQARARLEGIIHPLVAAHGDSRAQQALAAGAGLIVHDIPLLAESGPSGPWARRLDAVVVVDCLAETQIERVMRRSGL
AREQVQGIIASQASRSARRALADVVLANEADGTLQQLQAEVRQMARWFGL
>Mature_210_residues
MRRKPSRPLRVGLTGGIGSGKSTVGQMLAALGACLIDADQISREVTGPQGAAMAAIRSTFGAEYVDACGALDRARMRQLA
FSQPQARARLEGIIHPLVAAHGDSRAQQALAAGAGLIVHDIPLLAESGPSGPWARRLDAVVVVDCLAETQIERVMRRSGL
AREQVQGIIASQASRSARRALADVVLANEADGTLQQLQAEVRQMARWFGL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=189, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI191252795, Length=189, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI110227607, Length=191, Percent_Identity=29.3193717277487, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI110227605, Length=191, Percent_Identity=29.3193717277487, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227603, Length=191, Percent_Identity=29.3193717277487, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227601, Length=191, Percent_Identity=29.3193717277487, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI205277394, Length=191, Percent_Identity=29.3193717277487, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1786292, Length=203, Percent_Identity=37.9310344827586, Blast_Score=124, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17554944, Length=202, Percent_Identity=33.6633663366337, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320402, Length=207, Percent_Identity=31.4009661835749, Blast_Score=79, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24644728, Length=189, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24658602, Length=198, Percent_Identity=30.8080808080808, Blast_Score=90, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22210; Mature: 22210

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKPSRPLRVGLTGGIGSGKSTVGQMLAALGACLIDADQISREVTGPQGAAMAAIRSTF
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHH
GAEYVDACGALDRARMRQLAFSQPQARARLEGIIHPLVAAHGDSRAQQALAAGAGLIVHD
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHH
IPLLAESGPSGPWARRLDAVVVVDCLAETQIERVMRRSGLAREQVQGIIASQASRSARRA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LADVVLANEADGTLQQLQAEVRQMARWFGL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRKPSRPLRVGLTGGIGSGKSTVGQMLAALGACLIDADQISREVTGPQGAAMAAIRSTF
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHH
GAEYVDACGALDRARMRQLAFSQPQARARLEGIIHPLVAAHGDSRAQQALAAGAGLIVHD
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHH
IPLLAESGPSGPWARRLDAVVVVDCLAETQIERVMRRSGLAREQVQGIIASQASRSARRA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LADVVLANEADGTLQQLQAEVRQMARWFGL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA