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The map label for this gene is frc [H]

Identifier: 121610783

GI number: 121610783

Start: 4259217

End: 4260497

Strand: Direct

Name: frc [H]

Synonym: Veis_3863

Alternate gene names: 121610783

Gene position: 4259217-4260497 (Clockwise)

Preceding gene: 121610782

Following gene: 121610784

Centisome position: 76.51

GC content: 64.17

Gene sequence:

>1281_bases
ATGGGCGTTGACAGCAGACAAGAGTATTCGAGAGCCCATATGACAACCTCACCCACTATGCCCGACGGGCAGCGCCAGCG
CGCCCCAAGCAGTGGCCCGCTCGATGGCATTCGCGTACTGGACCTGACTTCGGTCGTTCTCGGGCCCCTGGCGACCCAGG
TACTCGCGGACCTGGGCGCCGACGTGATCAAGATCGAAGGCCCAGAAGGCGACATGATGCGTGCCAACGGTGTGTCGCAG
CACGCCGGAATGAGCTCCATCTACTTGGCGCTGAACCGGAACAAGCGCTCGGTCGTGCTCGACCTCAAGAATGAGGAAGG
CGTCGCAGCGCTGAGGCACCTGATCGCGCAGGCGGACGTGCTCGTGCACAACATGCGCGTGGCCGCCATCGAGCGGCTGG
GCTTCGGCTATGAGGCCGTGGCAGCACTGAATCCGCGCTTGGTCTACTGCATGGCCACCGGTTTCGGGCAGGACGGACCG
TACAAGGACAAGCCCGCTTTCGACGACATCATCCAGGCGGGCTCCGGCTTGGTATCCCTGAACACGAACGGCGGCAACCG
GCCGGAGTATGTGCCCAGCCTGATCGCCGACAAGACTACGGGGCTCGTGCTGGCCAACGCAGTGCTGGCGGCTCTACTGC
ACCGCGAGCGCCGCGGCGTGGGACAGTGCGTGGAAGTGCCGATGCTGGAGACGATGGCCAGCTTCGTGCTGGCCGAGCAC
ATGGGTGGCATGACGTTCGAAGGTTCCACGGAAAGCGCGGGCTATGCGCGCTTGTTGCACGGCGGCCGACGGCCCTTGCA
GACCCGGGACGGCTGGATCTGCGCGCTCCCCTACACCGATCGCCACTGGCGCGCCTTCTTTCATGCGGTCGGCCGGGACG
ACATTGGCGATGACTGCCGGGTTGCAGACAAATCTCAGCGAAACGCCAACATCCGCAAGCTCTACCAGCGACTGGCTGAA
CTCATTCTTGAGCGCACGACAGCCGAATGGATGGACCTCTTTGAGCAATTGGACATTCCAGCGACACCCATCCATGCACT
CGGCGACCTGCCGGAACACCCGCATCTGAAAGCGGTCGGGCTGTTCCAGGAAACGCATCACCCGACGGAGGGCCCGCTCA
GGGAGATCCGTCCGCCGATGCGGTTTTCAGCCACGCCGCTCTCCTTGCGGCGGCACGCGCCCAGCCTGGGCGAGCACACC
CACGAAGTCTTGCTGGAAGCCGGCTTCACGCGCGAAGAGATGACGCGCGTCGTGGCAACAACGGCAACCGCGGTTGATTG
A

Upstream 100 bases:

>100_bases
GCCAATCAGCAGGAGTTGGCGATCCAGCGCGAGCAGTTCCGCACCGAGGATTTCCGCGAGGGCGTGGCCGCGATGGCGGC
GCGCCGCTTGCCCGTGTTCC

Downstream 100 bases:

>100_bases
AACCCCTTGAGGAACGTATCGTGAATTTCAAACTGGAAGAAGAACACCAGATGATCCAGGACTTGGTGGCCCGCTTTGTG
CGCGAGCAGTTGATGCCACT

Product: formyl-CoA transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MGVDSRQEYSRAHMTTSPTMPDGQRQRAPSSGPLDGIRVLDLTSVVLGPLATQVLADLGADVIKIEGPEGDMMRANGVSQ
HAGMSSIYLALNRNKRSVVLDLKNEEGVAALRHLIAQADVLVHNMRVAAIERLGFGYEAVAALNPRLVYCMATGFGQDGP
YKDKPAFDDIIQAGSGLVSLNTNGGNRPEYVPSLIADKTTGLVLANAVLAALLHRERRGVGQCVEVPMLETMASFVLAEH
MGGMTFEGSTESAGYARLLHGGRRPLQTRDGWICALPYTDRHWRAFFHAVGRDDIGDDCRVADKSQRNANIRKLYQRLAE
LILERTTAEWMDLFEQLDIPATPIHALGDLPEHPHLKAVGLFQETHHPTEGPLREIRPPMRFSATPLSLRRHAPSLGEHT
HEVLLEAGFTREEMTRVVATTATAVD

Sequences:

>Translated_426_residues
MGVDSRQEYSRAHMTTSPTMPDGQRQRAPSSGPLDGIRVLDLTSVVLGPLATQVLADLGADVIKIEGPEGDMMRANGVSQ
HAGMSSIYLALNRNKRSVVLDLKNEEGVAALRHLIAQADVLVHNMRVAAIERLGFGYEAVAALNPRLVYCMATGFGQDGP
YKDKPAFDDIIQAGSGLVSLNTNGGNRPEYVPSLIADKTTGLVLANAVLAALLHRERRGVGQCVEVPMLETMASFVLAEH
MGGMTFEGSTESAGYARLLHGGRRPLQTRDGWICALPYTDRHWRAFFHAVGRDDIGDDCRVADKSQRNANIRKLYQRLAE
LILERTTAEWMDLFEQLDIPATPIHALGDLPEHPHLKAVGLFQETHHPTEGPLREIRPPMRFSATPLSLRRHAPSLGEHT
HEVLLEAGFTREEMTRVVATTATAVD
>Mature_425_residues
GVDSRQEYSRAHMTTSPTMPDGQRQRAPSSGPLDGIRVLDLTSVVLGPLATQVLADLGADVIKIEGPEGDMMRANGVSQH
AGMSSIYLALNRNKRSVVLDLKNEEGVAALRHLIAQADVLVHNMRVAAIERLGFGYEAVAALNPRLVYCMATGFGQDGPY
KDKPAFDDIIQAGSGLVSLNTNGGNRPEYVPSLIADKTTGLVLANAVLAALLHRERRGVGQCVEVPMLETMASFVLAEHM
GGMTFEGSTESAGYARLLHGGRRPLQTRDGWICALPYTDRHWRAFFHAVGRDDIGDDCRVADKSQRNANIRKLYQRLAEL
ILERTTAEWMDLFEQLDIPATPIHALGDLPEHPHLKAVGLFQETHHPTEGPLREIRPPMRFSATPLSLRRHAPSLGEHTH
EVLLEAGFTREEMTRVVATTATAVD

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=378, Percent_Identity=31.2169312169312, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI300863124, Length=404, Percent_Identity=29.7029702970297, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI300863126, Length=378, Percent_Identity=29.6296296296296, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI13376042, Length=404, Percent_Identity=26.980198019802, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI42794625, Length=393, Percent_Identity=30.0254452926209, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI266456254, Length=393, Percent_Identity=30.0254452926209, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI266458393, Length=203, Percent_Identity=35.9605911330049, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI266458397, Length=203, Percent_Identity=35.9605911330049, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI42822893, Length=130, Percent_Identity=38.4615384615385, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI266458395, Length=130, Percent_Identity=38.4615384615385, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI87082093, Length=343, Percent_Identity=32.9446064139942, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1788717, Length=408, Percent_Identity=31.1274509803922, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1786222, Length=416, Percent_Identity=25.4807692307692, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115535051, Length=330, Percent_Identity=26.0606060606061, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32564160, Length=331, Percent_Identity=25.6797583081571, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24648431, Length=392, Percent_Identity=33.6734693877551, Blast_Score=211, Evalue=8e-55,
Organism=Drosophila melanogaster, GI24585488, Length=365, Percent_Identity=30.1369863013699, Blast_Score=111, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 46637; Mature: 46506

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVDSRQEYSRAHMTTSPTMPDGQRQRAPSSGPLDGIRVLDLTSVVLGPLATQVLADLGA
CCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCC
DVIKIEGPEGDMMRANGVSQHAGMSSIYLALNRNKRSVVLDLKNEEGVAALRHLIAQADV
CEEEEECCCCCCEECCCCHHHCCCEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHH
LVHNMRVAAIERLGFGYEAVAALNPRLVYCMATGFGQDGPYKDKPAFDDIIQAGSGLVSL
HHHHHHHHHHHHHCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCEEEE
NTNGGNRPEYVPSLIADKTTGLVLANAVLAALLHRERRGVGQCVEVPMLETMASFVLAEH
ECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
MGGMTFEGSTESAGYARLLHGGRRPLQTRDGWICALPYTDRHWRAFFHAVGRDDIGDDCR
HCCCEECCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCC
VADKSQRNANIRKLYQRLAELILERTTAEWMDLFEQLDIPATPIHALGDLPEHPHLKAVG
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCEEEE
LFQETHHPTEGPLREIRPPMRFSATPLSLRRHAPSLGEHTHEVLLEAGFTREEMTRVVAT
HHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
TATAVD
HHHHCC
>Mature Secondary Structure 
GVDSRQEYSRAHMTTSPTMPDGQRQRAPSSGPLDGIRVLDLTSVVLGPLATQVLADLGA
CCCCHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCC
DVIKIEGPEGDMMRANGVSQHAGMSSIYLALNRNKRSVVLDLKNEEGVAALRHLIAQADV
CEEEEECCCCCCEECCCCHHHCCCEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHH
LVHNMRVAAIERLGFGYEAVAALNPRLVYCMATGFGQDGPYKDKPAFDDIIQAGSGLVSL
HHHHHHHHHHHHHCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCEEEE
NTNGGNRPEYVPSLIADKTTGLVLANAVLAALLHRERRGVGQCVEVPMLETMASFVLAEH
ECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
MGGMTFEGSTESAGYARLLHGGRRPLQTRDGWICALPYTDRHWRAFFHAVGRDDIGDDCR
HCCCEECCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCC
VADKSQRNANIRKLYQRLAELILERTTAEWMDLFEQLDIPATPIHALGDLPEHPHLKAVG
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCEEEE
LFQETHHPTEGPLREIRPPMRFSATPLSLRRHAPSLGEHTHEVLLEAGFTREEMTRVVAT
HHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
TATAVD
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA