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The map label for this gene is glcD [H]

Identifier: 121610707

GI number: 121610707

Start: 4175199

End: 4176617

Strand: Direct

Name: glcD [H]

Synonym: Veis_3784

Alternate gene names: 121610707

Gene position: 4175199-4176617 (Clockwise)

Preceding gene: 121610706

Following gene: 121610710

Centisome position: 75.0

GC content: 69.27

Gene sequence:

>1419_bases
ATGACCCCCTTGCTCGACACCCTTGCCGCCCTGGTCGGCCCGGCCCATGTGATCACCGACGGCGATCTTTGCGCCTGGGA
GCAGGACTGGCGCCGCCGCGTGCGCGGCAAAGCCCTGGCCGTGGTGCGCCCGGCCAACACGCAGCAGGTGGCTGCGGTGG
TGCAGGCCTGCGCCGCAGCGGGCACCGCCATCGTGCCCCAAGGCGGCAACACCGGGCTGGCCGTGGGCTCCATCCCCGAC
GCCTCGGGCACGCAGATCGTGCTCGCCCTGACGCGCATGAACGCCGTGCGCAGCATCGACGCCGACAACCTCACGCTGAC
CGCAGAAGCCGGCTGCATCCTGCACAACCTGCAAGCTGCGGCGCACGACGCGGGGCTGCTGTTTCCGCTGTCGCTGGCGG
CCCAGGGCAGTTGCACCATCGGCGGCAACCTGGGCACCAACGCCGGCGGCACGCAGGTGCTGCGCTATGGCAATGCGCGC
GAGCTGTGCCTGGGCCTGGAAGTCGTCACGCCGCAGGGCCAGTGCTGGGACGGCCTGCGCGGCCTGCGCAAGGACAACAC
GGGTTACGACCTGCGCGACCTGTTCATCGGCAGCGAAGGCACGCTGGGCATCATCACCGCCGCCACGCTGCGGCTCTACC
CGCAGCCCGCAGCCCGCCTGACCGCCTGGGCCGCCGTGCCCGCGCTGGAACAAGCCGTGGCCCTGCTGGGCCTGGCCCGG
CAGCGGCTGGCTGCGGGCCTGACCGGCTTTGAGGTCATGGGCCAGTTCGCGCTGAGCCTGGTGGGCAAGCGCATGCCGCA
GTTGCGCGTGCCCTTCCTGGGCGAGCGCAACGCGCCCTGGTGCGTGCTGCTGGAAAACTGCGACAGCGAATCCGAAGAAC
ATGCCCGGGCGGGCTTTGAAGCGCTGCTGCAAGCAGCCTTCGACGCCGGCTGCGTGAGCAACGCCGTGGTCGCCGAAAAC
CTGGCGCAGGCCAATCAACTGTGGCAGATCCGCGAAAGCATTCCGCTGGCCCAGGCCGAAGAAGGCCCGAACGTCAAACA
CGATATCGCGCTACGGATTTCATGCATCCCGGCATTCGTTGCGCACACCGACGCGCTGTTGCAGCGCAGCATCCCGGGCG
TGCGCCTGGTCAACTTCGGCCACCTGGGCGACGGCAACCTGCACTACAACGTGCAGGCCCCCGCCGGCGGCGACCCCCAA
GCCTTCCTGCGCGAGCATGAGCCGGCCATCAACCAACTGGTATATGCCGCCGTGGCCGAGTTCGGCGGCTCCTTCTCGGC
AGAGCACGGCATAGGCTCGCTGAAGGTCGACAAGCTCGAACGCTACCAATCGCCGGTGGCGCTCACGCTGATGCGCGCGA
TCAAGCAGGCCCTGGATCCGCAGGGGATCATGAACCCGGGGCGGGTGTTGAGGGCCTGA

Upstream 100 bases:

>100_bases
TGCGCCAGCGCAATCACGCGCCGGTGGCGCCGGCCCGCTCGCAGGCCGAGACACCCGAGCGCGCCGCGCCGCCCGCCCAC
TGAAGAAAAGAACCCCGCCC

Downstream 100 bases:

>100_bases
GACAGGCGCTGAACGGGCGTCGTTCGGACCCTGGGCAGAAGGCAACGCAGGCCGATGCGCTCGGCCAGACCTGTAGCGGC
CTGTAGCGGTTTGCATCGGT

Product: FAD linked oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MTPLLDTLAALVGPAHVITDGDLCAWEQDWRRRVRGKALAVVRPANTQQVAAVVQACAAAGTAIVPQGGNTGLAVGSIPD
ASGTQIVLALTRMNAVRSIDADNLTLTAEAGCILHNLQAAAHDAGLLFPLSLAAQGSCTIGGNLGTNAGGTQVLRYGNAR
ELCLGLEVVTPQGQCWDGLRGLRKDNTGYDLRDLFIGSEGTLGIITAATLRLYPQPAARLTAWAAVPALEQAVALLGLAR
QRLAAGLTGFEVMGQFALSLVGKRMPQLRVPFLGERNAPWCVLLENCDSESEEHARAGFEALLQAAFDAGCVSNAVVAEN
LAQANQLWQIRESIPLAQAEEGPNVKHDIALRISCIPAFVAHTDALLQRSIPGVRLVNFGHLGDGNLHYNVQAPAGGDPQ
AFLREHEPAINQLVYAAVAEFGGSFSAEHGIGSLKVDKLERYQSPVALTLMRAIKQALDPQGIMNPGRVLRA

Sequences:

>Translated_472_residues
MTPLLDTLAALVGPAHVITDGDLCAWEQDWRRRVRGKALAVVRPANTQQVAAVVQACAAAGTAIVPQGGNTGLAVGSIPD
ASGTQIVLALTRMNAVRSIDADNLTLTAEAGCILHNLQAAAHDAGLLFPLSLAAQGSCTIGGNLGTNAGGTQVLRYGNAR
ELCLGLEVVTPQGQCWDGLRGLRKDNTGYDLRDLFIGSEGTLGIITAATLRLYPQPAARLTAWAAVPALEQAVALLGLAR
QRLAAGLTGFEVMGQFALSLVGKRMPQLRVPFLGERNAPWCVLLENCDSESEEHARAGFEALLQAAFDAGCVSNAVVAEN
LAQANQLWQIRESIPLAQAEEGPNVKHDIALRISCIPAFVAHTDALLQRSIPGVRLVNFGHLGDGNLHYNVQAPAGGDPQ
AFLREHEPAINQLVYAAVAEFGGSFSAEHGIGSLKVDKLERYQSPVALTLMRAIKQALDPQGIMNPGRVLRA
>Mature_471_residues
TPLLDTLAALVGPAHVITDGDLCAWEQDWRRRVRGKALAVVRPANTQQVAAVVQACAAAGTAIVPQGGNTGLAVGSIPDA
SGTQIVLALTRMNAVRSIDADNLTLTAEAGCILHNLQAAAHDAGLLFPLSLAAQGSCTIGGNLGTNAGGTQVLRYGNARE
LCLGLEVVTPQGQCWDGLRGLRKDNTGYDLRDLFIGSEGTLGIITAATLRLYPQPAARLTAWAAVPALEQAVALLGLARQ
RLAAGLTGFEVMGQFALSLVGKRMPQLRVPFLGERNAPWCVLLENCDSESEEHARAGFEALLQAAFDAGCVSNAVVAENL
AQANQLWQIRESIPLAQAEEGPNVKHDIALRISCIPAFVAHTDALLQRSIPGVRLVNFGHLGDGNLHYNVQAPAGGDPQA
FLREHEPAINQLVYAAVAEFGGSFSAEHGIGSLKVDKLERYQSPVALTLMRAIKQALDPQGIMNPGRVLRA

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=458, Percent_Identity=37.9912663755458, Blast_Score=280, Evalue=2e-75,
Organism=Homo sapiens, GI37595756, Length=497, Percent_Identity=30.9859154929577, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI37595754, Length=520, Percent_Identity=29.8076923076923, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI4501993, Length=207, Percent_Identity=32.3671497584541, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI1789351, Length=465, Percent_Identity=27.741935483871, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI48994907, Length=219, Percent_Identity=27.3972602739726, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI48994914, Length=176, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17534361, Length=459, Percent_Identity=32.6797385620915, Blast_Score=257, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI71992373, Length=446, Percent_Identity=29.1479820627803, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71992381, Length=446, Percent_Identity=28.0269058295964, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71992392, Length=370, Percent_Identity=30.8108108108108, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17556096, Length=204, Percent_Identity=26.4705882352941, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320023, Length=456, Percent_Identity=35.5263157894737, Blast_Score=305, Evalue=7e-84,
Organism=Saccharomyces cerevisiae, GI6320764, Length=456, Percent_Identity=32.8947368421053, Blast_Score=276, Evalue=6e-75,
Organism=Saccharomyces cerevisiae, GI6320027, Length=451, Percent_Identity=26.8292682926829, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI18921117, Length=461, Percent_Identity=36.2255965292842, Blast_Score=284, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24639277, Length=461, Percent_Identity=36.2255965292842, Blast_Score=284, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24639275, Length=461, Percent_Identity=36.2255965292842, Blast_Score=284, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24653753, Length=216, Percent_Identity=28.7037037037037, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 49784; Mature: 49652

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLLDTLAALVGPAHVITDGDLCAWEQDWRRRVRGKALAVVRPANTQQVAAVVQACAAA
CCHHHHHHHHHHCCCCEEECCCEECCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHC
GTAIVPQGGNTGLAVGSIPDASGTQIVLALTRMNAVRSIDADNLTLTAEAGCILHNLQAA
CCEEEECCCCCCEEECCCCCCCCCEEEEEEHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
AHDAGLLFPLSLAAQGSCTIGGNLGTNAGGTQVLRYGNARELCLGLEVVTPQGQCWDGLR
HCCCCEEEEEHHCCCCCEEECCCCCCCCCCCCEEECCCHHHEEEEEEEECCCCCCHHHHH
GLRKDNTGYDLRDLFIGSEGTLGIITAATLRLYPQPAARLTAWAAVPALEQAVALLGLAR
HHCCCCCCCCHHHEEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
QRLAAGLTGFEVMGQFALSLVGKRMPQLRVPFLGERNAPWCVLLENCDSESEEHARAGFE
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
ALLQAAFDAGCVSNAVVAENLAQANQLWQIRESIPLAQAEEGPNVKHDIALRISCIPAFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEHHHHHH
AHTDALLQRSIPGVRLVNFGHLGDGNLHYNVQAPAGGDPQAFLREHEPAINQLVYAAVAE
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHH
FGGSFSAEHGIGSLKVDKLERYQSPVALTLMRAIKQALDPQGIMNPGRVLRA
HCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHCC
>Mature Secondary Structure 
TPLLDTLAALVGPAHVITDGDLCAWEQDWRRRVRGKALAVVRPANTQQVAAVVQACAAA
CHHHHHHHHHHCCCCEEECCCEECCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHC
GTAIVPQGGNTGLAVGSIPDASGTQIVLALTRMNAVRSIDADNLTLTAEAGCILHNLQAA
CCEEEECCCCCCEEECCCCCCCCCEEEEEEHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
AHDAGLLFPLSLAAQGSCTIGGNLGTNAGGTQVLRYGNARELCLGLEVVTPQGQCWDGLR
HCCCCEEEEEHHCCCCCEEECCCCCCCCCCCCEEECCCHHHEEEEEEEECCCCCCHHHHH
GLRKDNTGYDLRDLFIGSEGTLGIITAATLRLYPQPAARLTAWAAVPALEQAVALLGLAR
HHCCCCCCCCHHHEEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
QRLAAGLTGFEVMGQFALSLVGKRMPQLRVPFLGERNAPWCVLLENCDSESEEHARAGFE
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
ALLQAAFDAGCVSNAVVAENLAQANQLWQIRESIPLAQAEEGPNVKHDIALRISCIPAFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEHHHHHH
AHTDALLQRSIPGVRLVNFGHLGDGNLHYNVQAPAGGDPQAFLREHEPAINQLVYAAVAE
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHH
FGGSFSAEHGIGSLKVDKLERYQSPVALTLMRAIKQALDPQGIMNPGRVLRA
HCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]