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The map label for this gene is mtaD [H]

Identifier: 121610576

GI number: 121610576

Start: 4035155

End: 4036588

Strand: Direct

Name: mtaD [H]

Synonym: Veis_3649

Alternate gene names: 121610576

Gene position: 4035155-4036588 (Clockwise)

Preceding gene: 121610575

Following gene: 121610577

Centisome position: 72.49

GC content: 71.27

Gene sequence:

>1434_bases
ATGGCGCCTGAGCAGACCGCGCAGCGCAGCCTGTTTGCGGCACAGGCCCTGCTGCCCGGCGGCTGGGCGCGCAACGTGCT
CGTGCAATGGGATGCGGCCGGGCGCATCACCGGCGTGGACACCGATGCCAGGGCGCCGGCCGGCCGGCCCGTGGCCGCAG
GGCCGCTGCTGCCGGGCCTGCCGAACCTGCACTCGCATGCCTTCCAGCGCGCGTTCGCCGGCCTGGCCGAATACCGCGCC
GAACGCCAGGACAGCTTCTGGAGTTGGCGCCAACTGATGTACCGCTTTGCAGCGCACATCACACCCGGGCAGATGCAAGC
CATCGCCACCTGGCTCTACGTGGAGATGCTGGAGGCCGGCTACACCCGGGTGTGCGAGTTCCACTACCTGCACCACGACC
ACACTGGCCAGCCCTATGCCGACGACGCCCGGATGTCGCTGGCGCTGCTGCACGCCGCGCGCACGGCCGGCATCGGCATC
ACACTGCTGCCGGCGCTGTACCAAAGCAGCGGATTTGGCGCCCGGCCGCCGCACGCGCAGCAAGCGCGCTTCATCCGCAG
CACCGCCAGCATGCTCTCGTTATTGGAGCGCCTGAGGCCCATCGCACAAGCGCAGGGCGCTGTGCTGGGCCTGGCTTTGC
ATTCGCTGCGCGCGGTGCCGCCGGACAGCCTGCAGGCCGCCGTGCAGGGCATCACGGCGCTGGACCCCCAGGCCCCGATC
CACATCCACATCGCCGAGCAGCAGCAAGAAGTCGACGACTGCATCGCCTGGAGCGGACAGCGCCCGGTGCAATGGCTGCT
CGATCACGCCCCGGTGGACGCACGCTGGTGCCTGGTGCACGCCACCCGGATGACGCCCGACGAACATGCCGCCGCCGCGC
GCACCGGCGCCGTGGTCGGCCTGTGCCCCAGCACCGAGGCCAACCTGGGCGACGGCATCTTCGACCTGCCGCTGTGGTTG
CAGCATGGCGGCCGCTGGGGCCTGGGCTCGGACAGCCATATCTGCGTGAATGCGGCCGAAGAACTACTGCTGCTCGAATA
CGGCCAGCGCCTGTCGCGCCGCCAGCGCAACGTGCTGGCCCATGCCACGCAGCCCGAAGTAGCCACCGCGATGAGCTTGC
AGGCCGTGCAGGGCGGCGCACAGGCCGCCGGGCACGGCATCGGTGCGGGCCTGGCAGGCATCGCCGTCGGCCGGCAGGCC
GACCTGGTGGTGCTCGACGCGCAGCATCTGGCGCTGCGCGGCCTGCCCGCGCACAGCATGCTCTCGGCCCATGTATTCGG
CAGCCAGCGCAGTTCAGCCCTGGACAGCCTGTGGGTGGCCGGCGTGCGCCGCGTCACCCAAGGCCGGCACGCGCTGCACG
AGGCGGCGGCCCAGGACTTCATCGCCGCCCGCAGCGCCATCATTGCGGCGCAACGCGCCGGAGCGATCCGCTAA

Upstream 100 bases:

>100_bases
TGGCTCGGGCACAAGCCCGCCTGCACCATCGTGCGCCAGGGCCGCGTGGTCCGCGACGGGCTGGGCCTGCTCGACAGGCC
GGAAATGCCGGTGCTGCGCG

Downstream 100 bases:

>100_bases
GCTGTGCGCCGCTCTGCCATCTGCCACTCGCCATTTGCCGCCCACCATCTGCCACTCGCCGGACACGCCATGACGACCAC
CACCGCCCCACCCGCGTTCA

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MAPEQTAQRSLFAAQALLPGGWARNVLVQWDAAGRITGVDTDARAPAGRPVAAGPLLPGLPNLHSHAFQRAFAGLAEYRA
ERQDSFWSWRQLMYRFAAHITPGQMQAIATWLYVEMLEAGYTRVCEFHYLHHDHTGQPYADDARMSLALLHAARTAGIGI
TLLPALYQSSGFGARPPHAQQARFIRSTASMLSLLERLRPIAQAQGAVLGLALHSLRAVPPDSLQAAVQGITALDPQAPI
HIHIAEQQQEVDDCIAWSGQRPVQWLLDHAPVDARWCLVHATRMTPDEHAAAARTGAVVGLCPSTEANLGDGIFDLPLWL
QHGGRWGLGSDSHICVNAAEELLLLEYGQRLSRRQRNVLAHATQPEVATAMSLQAVQGGAQAAGHGIGAGLAGIAVGRQA
DLVVLDAQHLALRGLPAHSMLSAHVFGSQRSSALDSLWVAGVRRVTQGRHALHEAAAQDFIAARSAIIAAQRAGAIR

Sequences:

>Translated_477_residues
MAPEQTAQRSLFAAQALLPGGWARNVLVQWDAAGRITGVDTDARAPAGRPVAAGPLLPGLPNLHSHAFQRAFAGLAEYRA
ERQDSFWSWRQLMYRFAAHITPGQMQAIATWLYVEMLEAGYTRVCEFHYLHHDHTGQPYADDARMSLALLHAARTAGIGI
TLLPALYQSSGFGARPPHAQQARFIRSTASMLSLLERLRPIAQAQGAVLGLALHSLRAVPPDSLQAAVQGITALDPQAPI
HIHIAEQQQEVDDCIAWSGQRPVQWLLDHAPVDARWCLVHATRMTPDEHAAAARTGAVVGLCPSTEANLGDGIFDLPLWL
QHGGRWGLGSDSHICVNAAEELLLLEYGQRLSRRQRNVLAHATQPEVATAMSLQAVQGGAQAAGHGIGAGLAGIAVGRQA
DLVVLDAQHLALRGLPAHSMLSAHVFGSQRSSALDSLWVAGVRRVTQGRHALHEAAAQDFIAARSAIIAAQRAGAIR
>Mature_476_residues
APEQTAQRSLFAAQALLPGGWARNVLVQWDAAGRITGVDTDARAPAGRPVAAGPLLPGLPNLHSHAFQRAFAGLAEYRAE
RQDSFWSWRQLMYRFAAHITPGQMQAIATWLYVEMLEAGYTRVCEFHYLHHDHTGQPYADDARMSLALLHAARTAGIGIT
LLPALYQSSGFGARPPHAQQARFIRSTASMLSLLERLRPIAQAQGAVLGLALHSLRAVPPDSLQAAVQGITALDPQAPIH
IHIAEQQQEVDDCIAWSGQRPVQWLLDHAPVDARWCLVHATRMTPDEHAAAARTGAVVGLCPSTEANLGDGIFDLPLWLQ
HGGRWGLGSDSHICVNAAEELLLLEYGQRLSRRQRNVLAHATQPEVATAMSLQAVQGGAQAAGHGIGAGLAGIAVGRQAD
LVVLDAQHLALRGLPAHSMLSAHVFGSQRSSALDSLWVAGVRRVTQGRHALHEAAAQDFIAARSAIIAAQRAGAIR

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540282, Length=440, Percent_Identity=29.7727272727273, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 51197; Mature: 51066

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPEQTAQRSLFAAQALLPGGWARNVLVQWDAAGRITGVDTDARAPAGRPVAAGPLLPGL
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCC
PNLHSHAFQRAFAGLAEYRAERQDSFWSWRQLMYRFAAHITPGQMQAIATWLYVEMLEAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
YTRVCEFHYLHHDHTGQPYADDARMSLALLHAARTAGIGITLLPALYQSSGFGARPPHAQ
HHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHH
QARFIRSTASMLSLLERLRPIAQAQGAVLGLALHSLRAVPPDSLQAAVQGITALDPQAPI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCE
HIHIAEQQQEVDDCIAWSGQRPVQWLLDHAPVDARWCLVHATRMTPDEHAAAARTGAVVG
EEEECCHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEE
LCPSTEANLGDGIFDLPLWLQHGGRWGLGSDSHICVNAAEELLLLEYGQRLSRRQRNVLA
ECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
HATQPEVATAMSLQAVQGGAQAAGHGIGAGLAGIAVGRQADLVVLDAQHLALRGLPAHSM
CCCCCHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHCCCCCCEEEEECHHHHHCCCCHHHH
LSAHVFGSQRSSALDSLWVAGVRRVTQGRHALHEAAAQDFIAARSAIIAAQRAGAIR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
APEQTAQRSLFAAQALLPGGWARNVLVQWDAAGRITGVDTDARAPAGRPVAAGPLLPGL
CCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCC
PNLHSHAFQRAFAGLAEYRAERQDSFWSWRQLMYRFAAHITPGQMQAIATWLYVEMLEAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
YTRVCEFHYLHHDHTGQPYADDARMSLALLHAARTAGIGITLLPALYQSSGFGARPPHAQ
HHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHH
QARFIRSTASMLSLLERLRPIAQAQGAVLGLALHSLRAVPPDSLQAAVQGITALDPQAPI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCE
HIHIAEQQQEVDDCIAWSGQRPVQWLLDHAPVDARWCLVHATRMTPDEHAAAARTGAVVG
EEEECCHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEE
LCPSTEANLGDGIFDLPLWLQHGGRWGLGSDSHICVNAAEELLLLEYGQRLSRRQRNVLA
ECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
HATQPEVATAMSLQAVQGGAQAAGHGIGAGLAGIAVGRQADLVVLDAQHLALRGLPAHSM
CCCCCHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHCCCCCCEEEEECHHHHHCCCCHHHH
LSAHVFGSQRSSALDSLWVAGVRRVTQGRHALHEAAAQDFIAARSAIIAAQRAGAIR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA