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The map label for this gene is hutI

Identifier: 121610575

GI number: 121610575

Start: 4033795

End: 4035165

Strand: Direct

Name: hutI

Synonym: Veis_3648

Alternate gene names: 121610575

Gene position: 4033795-4035165 (Clockwise)

Preceding gene: 121610574

Following gene: 121610576

Centisome position: 72.46

GC content: 71.19

Gene sequence:

>1371_bases
ATGACGATGCACGACACCCCGAGCGGCTTGAACTGGGACCTGGGCTTGGCCCCGCCGGCCGACGGCCTGTGGTGCGGCCT
GCGGCTGGTGGCCGAACTGACGCAGGCCGACCAACCCCTGCCCGCCGATGCGCCGGCCTGCCTGGTGGTGCAAGGCGGCA
TGCTGCGCTGGGTCGGGCCACAGGCGCAGTTGCCTGCGGCGTTCAGCGCCTTGCGCCGATTCGATGCGCGGGACGCGGCG
CGCACGGGCGCGCACGGCGCAGCGCCCGGAGCGCCTGGCACATTGGCCACCCCGGCGCTGGTCGACTGCCACACGCACCT
GGTGTACGGCGGGCAGCGCGCCGACGAATTCGCGCTGCGCCTGGCAGGCGCCAGCTACGAAGCACTGGCGCAGGCCGGCG
GCGGCATCCTGGCGTCGGTGCAGGCCACGCGCGCAGCCAGCGAAGACCAATTGTTCGCGCTCGCCATGCCGCGCCTGCAA
GCCTTGCTGGCCGAAGGTGTGGGCGCCATCGAAATCAAGTCCGGCTACGGCCTGGCGCTCGAACATGAGCGCAAGCAGTT
GCGCGTGGCCCGCCGTCTGGGCCAGGCTTGCGCGGTGACGGTGCGCACCAGTTTCCTCGGCGCCCATGCCTTGCCGCCCG
AATATGCAGGCCGCAGCCAGGACTACATCGATCTGGTCTGCCAGCAGATGCTGCCCGCGCTGGCCGAGCAGGGGCTGGTC
GATGCGGTGGACATGTTTTGCGAGCGCATTGCCTTCACGCTGGCAGAGACCGAGCAGGTCTTCCTGGCCGCGCAGCAACT
GGGCCTTCCCGTCAAACTGCACGCCGGGCAGTTGTCGGACATGGGCGGGGCCGCCTTGGCGGCGCGCTACGGCGCGCTGT
CATGCGACCACCTGGAGCACCTGTCTGCCGACGCCATTGCCGCAATGCAAGCGGCCGGCACCGTGGCCGTGCTCTTGCCC
GGCGCCTGGTACACGCTGCGCGGGCAACAGCGCCCGCCGATCGAGGCCCTGCGCGCAGCCGGCGTGCCGATGGCCGTGGC
CACCGACCACAACCCCGGCAGTTCGCCGGCGCTGAGCCTGCTGCTGATGGCCCATATGGCCTGCACCCTGTTTCACCTGA
GCCTGTCCGAGGCGCTGGCAGGCATCACCACCCATGCGGCACGCGCGCTGGGCCTGCAAGACTCGCACGGCCTGATCGCC
GCCGGCCGGCCGGCCAACTTCGTGCTGTGGCCCCTGCAAGAAGCCGCCGAACTGGTCTATTGGCTCGGGCACAAGCCCGC
CTGCACCATCGTGCGCCAGGGCCGCGTGGTCCGCGACGGGCTGGGCCTGCTCGACAGGCCGGAAATGCCGGTGCTGCGCG
ATGGCGCCTGA

Upstream 100 bases:

>100_bases
CCGGCGCCGGGGAAAAAACATGAACCCCGTCGGCCACGGGCGCAGGCTTCACATTTGCTTGCAGCCATTATTTTTGTAGC
GATGACAGGCACGCCCCGCC

Downstream 100 bases:

>100_bases
GCAGACCGCGCAGCGCAGCCTGTTTGCGGCACAGGCCCTGCTGCCCGGCGGCTGGGCGCGCAACGTGCTCGTGCAATGGG
ATGCGGCCGGGCGCATCACC

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTMHDTPSGLNWDLGLAPPADGLWCGLRLVAELTQADQPLPADAPACLVVQGGMLRWVGPQAQLPAAFSALRRFDARDAA
RTGAHGAAPGAPGTLATPALVDCHTHLVYGGQRADEFALRLAGASYEALAQAGGGILASVQATRAASEDQLFALAMPRLQ
ALLAEGVGAIEIKSGYGLALEHERKQLRVARRLGQACAVTVRTSFLGAHALPPEYAGRSQDYIDLVCQQMLPALAEQGLV
DAVDMFCERIAFTLAETEQVFLAAQQLGLPVKLHAGQLSDMGGAALAARYGALSCDHLEHLSADAIAAMQAAGTVAVLLP
GAWYTLRGQQRPPIEALRAAGVPMAVATDHNPGSSPALSLLLMAHMACTLFHLSLSEALAGITTHAARALGLQDSHGLIA
AGRPANFVLWPLQEAAELVYWLGHKPACTIVRQGRVVRDGLGLLDRPEMPVLRDGA

Sequences:

>Translated_456_residues
MTMHDTPSGLNWDLGLAPPADGLWCGLRLVAELTQADQPLPADAPACLVVQGGMLRWVGPQAQLPAAFSALRRFDARDAA
RTGAHGAAPGAPGTLATPALVDCHTHLVYGGQRADEFALRLAGASYEALAQAGGGILASVQATRAASEDQLFALAMPRLQ
ALLAEGVGAIEIKSGYGLALEHERKQLRVARRLGQACAVTVRTSFLGAHALPPEYAGRSQDYIDLVCQQMLPALAEQGLV
DAVDMFCERIAFTLAETEQVFLAAQQLGLPVKLHAGQLSDMGGAALAARYGALSCDHLEHLSADAIAAMQAAGTVAVLLP
GAWYTLRGQQRPPIEALRAAGVPMAVATDHNPGSSPALSLLLMAHMACTLFHLSLSEALAGITTHAARALGLQDSHGLIA
AGRPANFVLWPLQEAAELVYWLGHKPACTIVRQGRVVRDGLGLLDRPEMPVLRDGA
>Mature_455_residues
TMHDTPSGLNWDLGLAPPADGLWCGLRLVAELTQADQPLPADAPACLVVQGGMLRWVGPQAQLPAAFSALRRFDARDAAR
TGAHGAAPGAPGTLATPALVDCHTHLVYGGQRADEFALRLAGASYEALAQAGGGILASVQATRAASEDQLFALAMPRLQA
LLAEGVGAIEIKSGYGLALEHERKQLRVARRLGQACAVTVRTSFLGAHALPPEYAGRSQDYIDLVCQQMLPALAEQGLVD
AVDMFCERIAFTLAETEQVFLAAQQLGLPVKLHAGQLSDMGGAALAARYGALSCDHLEHLSADAIAAMQAAGTVAVLLPG
AWYTLRGQQRPPIEALRAAGVPMAVATDHNPGSSPALSLLLMAHMACTLFHLSLSEALAGITTHAARALGLQDSHGLIAA
GRPANFVLWPLQEAAELVYWLGHKPACTIVRQGRVVRDGLGLLDRPEMPVLRDGA

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=400, Percent_Identity=34, Blast_Score=205, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17555004, Length=368, Percent_Identity=34.2391304347826, Blast_Score=210, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_VEREI (A1WP07)

Other databases:

- EMBL:   CP000542
- RefSeq:   YP_998382.1
- ProteinModelPortal:   A1WP07
- SMR:   A1WP07
- STRING:   A1WP07
- GeneID:   4690508
- GenomeReviews:   CP000542_GR
- KEGG:   vei:Veis_3648
- NMPDR:   fig|391735.5.peg.3364
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   VEIS391735:VEIS_3648-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1

EC number: =3.5.2.7

Molecular weight: Translated: 47813; Mature: 47681

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: BINDING 113-113 BINDING 126-126 BINDING 176-176 BINDING 209-209 BINDING 277-277

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMHDTPSGLNWDLGLAPPADGLWCGLRLVAELTQADQPLPADAPACLVVQGGMLRWVGP
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEECC
QAQLPAAFSALRRFDARDAARTGAHGAAPGAPGTLATPALVDCHTHLVYGGQRADEFALR
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCHHHHHHH
LAGASYEALAQAGGGILASVQATRAASEDQLFALAMPRLQALLAEGVGAIEIKSGYGLAL
HCCCCHHHHHHCCCCEEEEEHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEE
EHERKQLRVARRLGQACAVTVRTSFLGAHALPPEYAGRSQDYIDLVCQQMLPALAEQGLV
HHHHHHHHHHHHHCHHHEEEHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCHH
DAVDMFCERIAFTLAETEQVFLAAQQLGLPVKLHAGQLSDMGGAALAARYGALSCDHLEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCCCHHHHHH
LSADAIAAMQAAGTVAVLLPGAWYTLRGQQRPPIEALRAAGVPMAVATDHNPGSSPALSL
CCHHHHHHHHHCCEEEEEECCCEEEECCCCCCCHHHHHHCCCCEEEEECCCCCCCHHHHH
LLMAHMACTLFHLSLSEALAGITTHAARALGLQDSHGLIAAGRPANFVLWPLQEAAELVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECHHHHHHHHH
WLGHKPACTIVRQGRVVRDGLGLLDRPEMPVLRDGA
HHCCCCCEEHHHCCEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TMHDTPSGLNWDLGLAPPADGLWCGLRLVAELTQADQPLPADAPACLVVQGGMLRWVGP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEECC
QAQLPAAFSALRRFDARDAARTGAHGAAPGAPGTLATPALVDCHTHLVYGGQRADEFALR
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCHHHHHHH
LAGASYEALAQAGGGILASVQATRAASEDQLFALAMPRLQALLAEGVGAIEIKSGYGLAL
HCCCCHHHHHHCCCCEEEEEHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEE
EHERKQLRVARRLGQACAVTVRTSFLGAHALPPEYAGRSQDYIDLVCQQMLPALAEQGLV
HHHHHHHHHHHHHCHHHEEEHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCHH
DAVDMFCERIAFTLAETEQVFLAAQQLGLPVKLHAGQLSDMGGAALAARYGALSCDHLEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCCCHHHHHH
LSADAIAAMQAAGTVAVLLPGAWYTLRGQQRPPIEALRAAGVPMAVATDHNPGSSPALSL
CCHHHHHHHHHCCEEEEEECCCEEEECCCCCCCHHHHHHCCCCEEEEECCCCCCCHHHHH
LLMAHMACTLFHLSLSEALAGITTHAARALGLQDSHGLIAAGRPANFVLWPLQEAAELVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECHHHHHHHHH
WLGHKPACTIVRQGRVVRDGLGLLDRPEMPVLRDGA
HHCCCCCEEHHHCCEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA