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The map label for this gene is betA [C]

Identifier: 121610508

GI number: 121610508

Start: 3957273

End: 3958892

Strand: Direct

Name: betA [C]

Synonym: Veis_3579

Alternate gene names: 121610508

Gene position: 3957273-3958892 (Clockwise)

Preceding gene: 121610507

Following gene: 121610509

Centisome position: 71.09

GC content: 66.11

Gene sequence:

>1620_bases
ATGGAAAACTACGACTACATCATCGCCGGCGGCGGCTCCGCCGGTTGCGTACTGGCCAACCGGCTGAGCGCTGACCCGTC
GGTCAGCGTGTTGCTCATCGAGGCCGGAGGGCCGGACCGGCACCCGCTGTTCCACTGGCCTGCCGGCTTTGCCAAGATGA
CCAAGGGCATTGCCTCCTGGGGCTGGAGCACGGTGCCGCAAAAGCACCTGCAAGGCCGGGTGCTGCGCTTTACCCAGGCC
AAGGTCATCGGAGGCGGCTCATCGATCAATGCCCAGCTCTACACCCGTGGCGCCGCCGCAGATTACGAGACCTGGGTGCG
GGACGCGGGCGCGCTCGGCTGGGGCTATGCCGACGTGCTGCCGTATTTCAAACGCTCGGAAAACAACCAGCGCTTTGCCA
ACGAGCACCACAGCTATGGCGGCCCGCTCGGGGTGTCCAACCCGGTCAGCCCATTGCCCATTTGCGAAGCCTTTTTTCAG
GCCGGGCAGGAGCTTGGCATCCCGTTCAATGCCGATTTCAACGGCGCCGCCCAGGATGGCCTGGGCTACTACCAACTGAC
GCAGTTGAACGCCCGCCGCTCATCGGGCGCGACCGCCTTTCTGAACCCGGTCAAACAGCGGCCGAATTTGACGATCAAGC
TGCACACCCGGGTGCTGAAAGTCCTGCTCGAAGGCCCGCGCGCAAGCCGCCGCGCAGCGGGTGTCACCTTGGTGACAGGC
AAAAGCCGCAGCCCGGCGACCCTGCGGGCTCACCGCGAGGTGATCGTCTCGTCAGGCGCGATCGGCTCGCCCCAATTGCT
GATGCTGTCAGGCATAGGCCCGGGCGCGCATTTGCGCAGCCTGGGATTGGACGTGGCCCATGACCTGCCCGGCGTGGGCG
CAAACCTGCAAGACCATCTGGACCTGTTCGTGATCGCCGAATGCACCGGCGATCACAGCTACGACAAATACGAGCGCCCG
CAGCACGCGGCCTGGGCCGGCTTGCAGTACCTGCTGTTCAAGCGCGGGCCGGTGGCATCGAGCCTGTTCGAGACCGGCGG
CTTTTGGTACGCCGACCGCAGCCACCCGGCGCACTCGCCCGACATACAACTGCACCTGGGCCTGGGCTCGGGGATCGAGG
CCGGCATGGCCAGGATGCAGAACTCCGGCGTGACCCTGAACAGCGCCTATCTGCGCCCCCAATCCCGGGGCAGCGTGCGG
CTGGCCAGCGCCGACCCTGGCGCCGCACCACTGATCGACCCCAACTACTGGGCCGACAGCCATGACCGCGCAATGGCCAT
CGGGGGCCTGCGGCTGGCGCGCGACATCATGCAGCAGCCGGCGCTCAGGCGCTATGTCAAAACCGAAGTACTGCCCGGCG
CCCGGCGACAAAGCGACCAAGACCTGTACGACTACGCCTGCGCCCATGCCAAGACCGACCACCACCCGGTCGGAACCTGC
CGGATCGGCCCGGAAAGCGACGCCCACAGCGTCGTGGCGCCAGACCTGAAGCTCATCGGCATCGAAGGCTTGCGCGTCGT
CGATGCATCGGTGATGCCCTTCGTGCCCTCCTGCAACACCAACGCGCCGACCATCATGGTGGCCGAAAAAGCCGCCGACC
ACATCCTTGCTCGTCTTTGA

Upstream 100 bases:

>100_bases
ACTGGCCAGCGGGCAGTTGGCTTTTGCCACCGGCAGCGCGCTGTCGGTGGACGGCGCGCTCTCCATTGCACGCTTATGAC
ATCGACGACGCTGATCACGC

Downstream 100 bases:

>100_bases
CCCAGCCCCTGGAGAACGCCATGCACATCCGTCTTCCGCAGATCGACGGGTCCGTCAAGACCTACGCCCTCAAAGCCAGC
CCCATAGCGCCCGCGCCTGC

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: SDH [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MENYDYIIAGGGSAGCVLANRLSADPSVSVLLIEAGGPDRHPLFHWPAGFAKMTKGIASWGWSTVPQKHLQGRVLRFTQA
KVIGGGSSINAQLYTRGAAADYETWVRDAGALGWGYADVLPYFKRSENNQRFANEHHSYGGPLGVSNPVSPLPICEAFFQ
AGQELGIPFNADFNGAAQDGLGYYQLTQLNARRSSGATAFLNPVKQRPNLTIKLHTRVLKVLLEGPRASRRAAGVTLVTG
KSRSPATLRAHREVIVSSGAIGSPQLLMLSGIGPGAHLRSLGLDVAHDLPGVGANLQDHLDLFVIAECTGDHSYDKYERP
QHAAWAGLQYLLFKRGPVASSLFETGGFWYADRSHPAHSPDIQLHLGLGSGIEAGMARMQNSGVTLNSAYLRPQSRGSVR
LASADPGAAPLIDPNYWADSHDRAMAIGGLRLARDIMQQPALRRYVKTEVLPGARRQSDQDLYDYACAHAKTDHHPVGTC
RIGPESDAHSVVAPDLKLIGIEGLRVVDASVMPFVPSCNTNAPTIMVAEKAADHILARL

Sequences:

>Translated_539_residues
MENYDYIIAGGGSAGCVLANRLSADPSVSVLLIEAGGPDRHPLFHWPAGFAKMTKGIASWGWSTVPQKHLQGRVLRFTQA
KVIGGGSSINAQLYTRGAAADYETWVRDAGALGWGYADVLPYFKRSENNQRFANEHHSYGGPLGVSNPVSPLPICEAFFQ
AGQELGIPFNADFNGAAQDGLGYYQLTQLNARRSSGATAFLNPVKQRPNLTIKLHTRVLKVLLEGPRASRRAAGVTLVTG
KSRSPATLRAHREVIVSSGAIGSPQLLMLSGIGPGAHLRSLGLDVAHDLPGVGANLQDHLDLFVIAECTGDHSYDKYERP
QHAAWAGLQYLLFKRGPVASSLFETGGFWYADRSHPAHSPDIQLHLGLGSGIEAGMARMQNSGVTLNSAYLRPQSRGSVR
LASADPGAAPLIDPNYWADSHDRAMAIGGLRLARDIMQQPALRRYVKTEVLPGARRQSDQDLYDYACAHAKTDHHPVGTC
RIGPESDAHSVVAPDLKLIGIEGLRVVDASVMPFVPSCNTNAPTIMVAEKAADHILARL
>Mature_539_residues
MENYDYIIAGGGSAGCVLANRLSADPSVSVLLIEAGGPDRHPLFHWPAGFAKMTKGIASWGWSTVPQKHLQGRVLRFTQA
KVIGGGSSINAQLYTRGAAADYETWVRDAGALGWGYADVLPYFKRSENNQRFANEHHSYGGPLGVSNPVSPLPICEAFFQ
AGQELGIPFNADFNGAAQDGLGYYQLTQLNARRSSGATAFLNPVKQRPNLTIKLHTRVLKVLLEGPRASRRAAGVTLVTG
KSRSPATLRAHREVIVSSGAIGSPQLLMLSGIGPGAHLRSLGLDVAHDLPGVGANLQDHLDLFVIAECTGDHSYDKYERP
QHAAWAGLQYLLFKRGPVASSLFETGGFWYADRSHPAHSPDIQLHLGLGSGIEAGMARMQNSGVTLNSAYLRPQSRGSVR
LASADPGAAPLIDPNYWADSHDRAMAIGGLRLARDIMQQPALRRYVKTEVLPGARRQSDQDLYDYACAHAKTDHHPVGTC
RIGPESDAHSVVAPDLKLIGIEGLRVVDASVMPFVPSCNTNAPTIMVAEKAADHILARL

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=543, Percent_Identity=40.8839779005525, Blast_Score=364, Evalue=1e-101,
Organism=Escherichia coli, GI1786503, Length=538, Percent_Identity=38.4758364312268, Blast_Score=341, Evalue=6e-95,
Organism=Caenorhabditis elegans, GI17532301, Length=546, Percent_Identity=37.7289377289377, Blast_Score=336, Evalue=2e-92,
Organism=Drosophila melanogaster, GI24642055, Length=584, Percent_Identity=35.958904109589, Blast_Score=322, Evalue=5e-88,
Organism=Drosophila melanogaster, GI24642042, Length=567, Percent_Identity=36.331569664903, Blast_Score=298, Evalue=6e-81,
Organism=Drosophila melanogaster, GI45551458, Length=573, Percent_Identity=36.1256544502618, Blast_Score=295, Evalue=7e-80,
Organism=Drosophila melanogaster, GI45549471, Length=573, Percent_Identity=36.1256544502618, Blast_Score=295, Evalue=7e-80,
Organism=Drosophila melanogaster, GI24642059, Length=576, Percent_Identity=35.0694444444444, Blast_Score=291, Evalue=7e-79,
Organism=Drosophila melanogaster, GI24642048, Length=567, Percent_Identity=34.3915343915344, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24642037, Length=575, Percent_Identity=35.6521739130435, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24642035, Length=581, Percent_Identity=35.9724612736661, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI17137792, Length=560, Percent_Identity=35.7142857142857, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24650267, Length=580, Percent_Identity=35.3448275862069, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI24642039, Length=565, Percent_Identity=35.0442477876106, Blast_Score=275, Evalue=8e-74,
Organism=Drosophila melanogaster, GI18859995, Length=569, Percent_Identity=33.0404217926186, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI18859993, Length=576, Percent_Identity=33.5069444444444, Blast_Score=251, Evalue=7e-67,
Organism=Drosophila melanogaster, GI24642051, Length=570, Percent_Identity=32.280701754386, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24642057, Length=584, Percent_Identity=29.4520547945205, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24645930, Length=577, Percent_Identity=29.9826689774697, Blast_Score=148, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.32 [H]

Molecular weight: Translated: 57916; Mature: 57916

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENYDYIIAGGGSAGCVLANRLSADPSVSVLLIEAGGPDRHPLFHWPAGFAKMTKGIASW
CCCCCEEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHC
GWSTVPQKHLQGRVLRFTQAKVIGGGSSINAQLYTRGAAADYETWVRDAGALGWGYADVL
CCCCCCHHHHCCEEEEEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCHHHHH
PYFKRSENNQRFANEHHSYGGPLGVSNPVSPLPICEAFFQAGQELGIPFNADFNGAAQDG
HHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCCC
LGYYQLTQLNARRSSGATAFLNPVKQRPNLTIKLHTRVLKVLLEGPRASRRAAGVTLVTG
CCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCHHHCCEEEEEC
KSRSPATLRAHREVIVSSGAIGSPQLLMLSGIGPGAHLRSLGLDVAHDLPGVGANLQDHL
CCCCCHHHHHHHHHEEECCCCCCCCEEEEECCCCCHHHHHHCCHHHHCCCCCCCCHHHCC
DLFVIAECTGDHSYDKYERPQHAAWAGLQYLLFKRGPVASSLFETGGFWYADRSHPAHSP
EEEEEEEECCCCCCCHHCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCCCCCCC
DIQLHLGLGSGIEAGMARMQNSGVTLNSAYLRPQSRGSVRLASADPGAAPLIDPNYWADS
CEEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCC
HDRAMAIGGLRLARDIMQQPALRRYVKTEVLPGARRQSDQDLYDYACAHAKTDHHPVGTC
CCCEEEHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEE
RIGPESDAHSVVAPDLKLIGIEGLRVVDASVMPFVPSCNTNAPTIMVAEKAADHILARL
ECCCCCCCCCEECCCEEEEECCCEEEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCC
>Mature Secondary Structure
MENYDYIIAGGGSAGCVLANRLSADPSVSVLLIEAGGPDRHPLFHWPAGFAKMTKGIASW
CCCCCEEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHC
GWSTVPQKHLQGRVLRFTQAKVIGGGSSINAQLYTRGAAADYETWVRDAGALGWGYADVL
CCCCCCHHHHCCEEEEEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCHHHHH
PYFKRSENNQRFANEHHSYGGPLGVSNPVSPLPICEAFFQAGQELGIPFNADFNGAAQDG
HHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCCC
LGYYQLTQLNARRSSGATAFLNPVKQRPNLTIKLHTRVLKVLLEGPRASRRAAGVTLVTG
CCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCHHHCCEEEEEC
KSRSPATLRAHREVIVSSGAIGSPQLLMLSGIGPGAHLRSLGLDVAHDLPGVGANLQDHL
CCCCCHHHHHHHHHEEECCCCCCCCEEEEECCCCCHHHHHHCCHHHHCCCCCCCCHHHCC
DLFVIAECTGDHSYDKYERPQHAAWAGLQYLLFKRGPVASSLFETGGFWYADRSHPAHSP
EEEEEEEECCCCCCCHHCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCCCCCCC
DIQLHLGLGSGIEAGMARMQNSGVTLNSAYLRPQSRGSVRLASADPGAAPLIDPNYWADS
CEEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCC
HDRAMAIGGLRLARDIMQQPALRRYVKTEVLPGARRQSDQDLYDYACAHAKTDHHPVGTC
CCCEEEHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEE
RIGPESDAHSVVAPDLKLIGIEGLRVVDASVMPFVPSCNTNAPTIMVAEKAADHILARL
ECCCCCCCCCEECCCEEEEECCCEEEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9023923 [H]