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The map label for this gene is fabG [H]

Identifier: 121610507

GI number: 121610507

Start: 3956460

End: 3957251

Strand: Direct

Name: fabG [H]

Synonym: Veis_3578

Alternate gene names: 121610507

Gene position: 3956460-3957251 (Clockwise)

Preceding gene: 121610506

Following gene: 121610508

Centisome position: 71.07

GC content: 69.95

Gene sequence:

>792_bases
GTGACGCGCCCTGCCTTGGCCATCGTCACCGGCGCCCGCCGTGGCATCGGGGCCGCCATCGCCATCGACCTGGCAGCCCA
TGGATTCGCCGTCGCCATGACCGATCTCGCCGACCCTGCCGATACCGCCGACCCCGGCGCCGCGCACACCCTGCACGCGA
TCGAGTCGCGCGCTGGCCGGGCCCGTTTTTTCCCTTCGGACCTGGCCCGGGTCGAGGCCCATCCGGCGCTGGTGCAAGCC
ATCGCCGATTGGGGCGGGCCGGTCGAGGTGCTGGTCAACAACGCCGGCATCGCCGCACCGAGCCGTGGCGATCTGCTCGA
TGTGCAGCCCCGCGCCTTCGACGAGGTGCTGGGCGTGAACCTGCGCGGAACCTTCTTCATGACCCAGGCCGTCGCGCGCC
ACATGCTGCAAACGACGCCGGCGCATCCGGCACGCCCGCGCACGATAGTGACACTGTCCTCGGTCAGCGCCGAACTGGCC
TCGATCGAACGCGCAGAGTATTGCCTGTCCAAGTCCGGGCTGCCCATGCTCACCAAACTGTTTGCGCTGCGCCTGGCAGC
GGCCGGCATCGCCGTGTTCGAGATCCGGCCCGGCATCATCCAAACGCCGATGACGCAGCCGGTGGCCGCCCAATACGGGC
AGCGCATCGCCGAAGGGCTGGTGCCCATGCAGCGCTGGGGGCAGCCCGAGGATGTGGCGCGCGCGGTGTCGGCACTGGCC
AGCGGGCAGTTGGCTTTTGCCACCGGCAGCGCGCTGTCGGTGGACGGCGCGCTCTCCATTGCACGCTTATGA

Upstream 100 bases:

>100_bases
TGGACGCGGGCTTTTTCCCTTCTTCGGCAGCCGTCAACCCGGCGCTGACGGTGGCCGCGCAGGCGCTGCGCGTGGGCCGG
CATCTTCGGGAGCAACTGTC

Downstream 100 bases:

>100_bases
CATCGACGACGCTGATCACGCATGGAAAACTACGACTACATCATCGCCGGCGGCGGCTCCGCCGGTTGCGTACTGGCCAA
CCGGCTGAGCGCTGACCCGT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTRPALAIVTGARRGIGAAIAIDLAAHGFAVAMTDLADPADTADPGAAHTLHAIESRAGRARFFPSDLARVEAHPALVQA
IADWGGPVEVLVNNAGIAAPSRGDLLDVQPRAFDEVLGVNLRGTFFMTQAVARHMLQTTPAHPARPRTIVTLSSVSAELA
SIERAEYCLSKSGLPMLTKLFALRLAAAGIAVFEIRPGIIQTPMTQPVAAQYGQRIAEGLVPMQRWGQPEDVARAVSALA
SGQLAFATGSALSVDGALSIARL

Sequences:

>Translated_263_residues
MTRPALAIVTGARRGIGAAIAIDLAAHGFAVAMTDLADPADTADPGAAHTLHAIESRAGRARFFPSDLARVEAHPALVQA
IADWGGPVEVLVNNAGIAAPSRGDLLDVQPRAFDEVLGVNLRGTFFMTQAVARHMLQTTPAHPARPRTIVTLSSVSAELA
SIERAEYCLSKSGLPMLTKLFALRLAAAGIAVFEIRPGIIQTPMTQPVAAQYGQRIAEGLVPMQRWGQPEDVARAVSALA
SGQLAFATGSALSVDGALSIARL
>Mature_262_residues
TRPALAIVTGARRGIGAAIAIDLAAHGFAVAMTDLADPADTADPGAAHTLHAIESRAGRARFFPSDLARVEAHPALVQAI
ADWGGPVEVLVNNAGIAAPSRGDLLDVQPRAFDEVLGVNLRGTFFMTQAVARHMLQTTPAHPARPRTIVTLSSVSAELAS
IERAEYCLSKSGLPMLTKLFALRLAAAGIAVFEIRPGIIQTPMTQPVAAQYGQRIAEGLVPMQRWGQPEDVARAVSALAS
GQLAFATGSALSVDGALSIARL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=35.2490421455939, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=30.3030303030303, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7705925, Length=176, Percent_Identity=33.5227272727273, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=29.8449612403101, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=29.1828793774319, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=28.4046692607004, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40254992, Length=257, Percent_Identity=29.1828793774319, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI83715985, Length=258, Percent_Identity=27.906976744186, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=32.1705426356589, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=32.9411764705882, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=33.203125, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790717, Length=260, Percent_Identity=29.6153846153846, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=27.8625954198473, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788459, Length=260, Percent_Identity=30.3846153846154, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789057, Length=267, Percent_Identity=28.0898876404494, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=31.3492063492063, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=27.9527559055118, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=31.3725490196078, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=264, Percent_Identity=32.5757575757576, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=271, Percent_Identity=29.1512915129151, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=29.2307692307692, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=28.125, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=267, Percent_Identity=30.3370786516854, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=27.9527559055118, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=28.4132841328413, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=278, Percent_Identity=26.2589928057554, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=26.4705882352941, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=286, Percent_Identity=26.5734265734266, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=24.8148148148148, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=26.2172284644195, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=207, Percent_Identity=23.6714975845411, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=266, Percent_Identity=26.6917293233083, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=32.9411764705882, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=32.5581395348837, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=28.90625, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17737361, Length=262, Percent_Identity=27.8625954198473, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357041, Length=262, Percent_Identity=27.8625954198473, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571526, Length=268, Percent_Identity=29.4776119402985, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355319, Length=265, Percent_Identity=26.7924528301887, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644337, Length=183, Percent_Identity=32.2404371584699, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27423; Mature: 27292

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPALAIVTGARRGIGAAIAIDLAAHGFAVAMTDLADPADTADPGAAHTLHAIESRAGR
CCCCCEEEEECCCCCCCHHEEEHHHHCCHHEEEHHCCCCCCCCCCCCHHHHHHHHHCCCC
ARFFPSDLARVEAHPALVQAIADWGGPVEVLVNNAGIAAPSRGDLLDVQPRAFDEVLGVN
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCHHHHHHHHCCC
LRGTFFMTQAVARHMLQTTPAHPARPRTIVTLSSVSAELASIERAEYCLSKSGLPMLTKL
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FALRLAAAGIAVFEIRPGIIQTPMTQPVAAQYGQRIAEGLVPMQRWGQPEDVARAVSALA
HHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHH
SGQLAFATGSALSVDGALSIARL
CCCEEEECCCCEEECCCCHHHCC
>Mature Secondary Structure 
TRPALAIVTGARRGIGAAIAIDLAAHGFAVAMTDLADPADTADPGAAHTLHAIESRAGR
CCCCEEEEECCCCCCCHHEEEHHHHCCHHEEEHHCCCCCCCCCCCCHHHHHHHHHCCCC
ARFFPSDLARVEAHPALVQAIADWGGPVEVLVNNAGIAAPSRGDLLDVQPRAFDEVLGVN
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCHHHHHHHHCCC
LRGTFFMTQAVARHMLQTTPAHPARPRTIVTLSSVSAELASIERAEYCLSKSGLPMLTKL
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FALRLAAAGIAVFEIRPGIIQTPMTQPVAAQYGQRIAEGLVPMQRWGQPEDVARAVSALA
HHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHH
SGQLAFATGSALSVDGALSIARL
CCCEEEECCCCEEECCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]