Click here to switch to the map view.

The map label for this gene is gsiD [H]

Identifier: 121610367

GI number: 121610367

Start: 3806915

End: 3807778

Strand: Direct

Name: gsiD [H]

Synonym: Veis_3435

Alternate gene names: 121610367

Gene position: 3806915-3807778 (Clockwise)

Preceding gene: 121610366

Following gene: 121610368

Centisome position: 68.39

GC content: 67.25

Gene sequence:

>864_bases
ATGGACCCGGTAAAAATGAATGAAGCACGCAGTATCCGGGTGCTGCGCTGGCTGCGCAGCGATCTGCGGGCGGCGCTCAG
CCTGGCTTTTCTGGTGCTCTTGCTGCTGCTGTCGGTCACGGCGCCATGGATCGCCCCGCACGCACCGAGCGCGCAAAATC
TCGATGCCACGCTGCAACCGATCTCCGGCGCGCATTGGCTGGGCACCGACGACCTGGGCCGCGACATTCTGAGCCGCATG
ATCCACGGCGCGCCAGTCACCCTCTACGCGAGCTTGCTGGCGGTCGGCGTGGCGATCGTGCTGGGCCTGCCGATCGGCCT
GCTGGCGGGCTACCTCGGCGGCTGGCTCGACGAAGTGGTCGGCCGGCTGATCGACACGCTGCTGTCGTTTCCGGCCATCG
TGCTGGCCATCGCCGTGACCGGCGCCCTGGGCATTGGCCTGACCAACGCGATGATCTCGGTCGGCATCGTGTTCGCGCCA
CAACTGGCGCGCATCGTGCGGGCGCGCACGCTGGTGGTCAAGCAGGAACTGTATGTGGATGCCGCGCGCTGCTTTGGCGC
GTCCACGCGCAGCATCCTGTGGCGCCATGTGCTGCCGAACACGATACAGCCGGTGATCGTGCAGATCACGCTGCTGTTGG
CCGGCGCCTTGCTGGCCGAAGCCAGCCTGAGCTTCCTGGGCCTGGGCATACAGCCGCCCAACGCCAGTTGGGGCGCCATG
CTCGCCCGCGCCTACCAGAACATGGAAATCGCGCCGGAGCAGATGTATGCGCCGGGCCTGGCGATCCTCTCGACCGCCAT
CGCGTTCAACACGCTCGGCGAGTCGCTGCGCGTGGCGCTCGACCCCACGCACCAGCGACTTTGA

Upstream 100 bases:

>100_bases
GGACTTGTAACCATCGACAGCCATATCCATATGCCATATGCCATATGGTCCATTTCTCGTAATGCAATGAGCCGACGTTT
TCTTGCCCACGGTATTTCAC

Downstream 100 bases:

>100_bases
TCCCGGCCGCAGTGCCGAACCAGTGACCTTCCCGAAGGAACGACATGACCCCGCTGACCCCAATGACCCGGCTGACCCCG
CAACAGGTTTTTGACGACAT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MDPVKMNEARSIRVLRWLRSDLRAALSLAFLVLLLLLSVTAPWIAPHAPSAQNLDATLQPISGAHWLGTDDLGRDILSRM
IHGAPVTLYASLLAVGVAIVLGLPIGLLAGYLGGWLDEVVGRLIDTLLSFPAIVLAIAVTGALGIGLTNAMISVGIVFAP
QLARIVRARTLVVKQELYVDAARCFGASTRSILWRHVLPNTIQPVIVQITLLLAGALLAEASLSFLGLGIQPPNASWGAM
LARAYQNMEIAPEQMYAPGLAILSTAIAFNTLGESLRVALDPTHQRL

Sequences:

>Translated_287_residues
MDPVKMNEARSIRVLRWLRSDLRAALSLAFLVLLLLLSVTAPWIAPHAPSAQNLDATLQPISGAHWLGTDDLGRDILSRM
IHGAPVTLYASLLAVGVAIVLGLPIGLLAGYLGGWLDEVVGRLIDTLLSFPAIVLAIAVTGALGIGLTNAMISVGIVFAP
QLARIVRARTLVVKQELYVDAARCFGASTRSILWRHVLPNTIQPVIVQITLLLAGALLAEASLSFLGLGIQPPNASWGAM
LARAYQNMEIAPEQMYAPGLAILSTAIAFNTLGESLRVALDPTHQRL
>Mature_287_residues
MDPVKMNEARSIRVLRWLRSDLRAALSLAFLVLLLLLSVTAPWIAPHAPSAQNLDATLQPISGAHWLGTDDLGRDILSRM
IHGAPVTLYASLLAVGVAIVLGLPIGLLAGYLGGWLDEVVGRLIDTLLSFPAIVLAIAVTGALGIGLTNAMISVGIVFAP
QLARIVRARTLVVKQELYVDAARCFGASTRSILWRHVLPNTIQPVIVQITLLLAGALLAEASLSFLGLGIQPPNASWGAM
LARAYQNMEIAPEQMYAPGLAILSTAIAFNTLGESLRVALDPTHQRL

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=286, Percent_Identity=43.3566433566434, Blast_Score=225, Evalue=2e-60,
Organism=Escherichia coli, GI1787760, Length=281, Percent_Identity=40.2135231316726, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1789964, Length=258, Percent_Identity=39.922480620155, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789889, Length=243, Percent_Identity=37.4485596707819, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1787549, Length=271, Percent_Identity=36.5313653136531, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1787498, Length=266, Percent_Identity=37.218045112782, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788505, Length=233, Percent_Identity=30.9012875536481, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30578; Mature: 30578

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPVKMNEARSIRVLRWLRSDLRAALSLAFLVLLLLLSVTAPWIAPHAPSAQNLDATLQP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCC
ISGAHWLGTDDLGRDILSRMIHGAPVTLYASLLAVGVAIVLGLPIGLLAGYLGGWLDEVV
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLIDTLLSFPAIVLAIAVTGALGIGLTNAMISVGIVFAPQLARIVRARTLVVKQELYVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARCFGASTRSILWRHVLPNTIQPVIVQITLLLAGALLAEASLSFLGLGIQPPNASWGAM
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LARAYQNMEIAPEQMYAPGLAILSTAIAFNTLGESLRVALDPTHQRL
HHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCHHCCC
>Mature Secondary Structure
MDPVKMNEARSIRVLRWLRSDLRAALSLAFLVLLLLLSVTAPWIAPHAPSAQNLDATLQP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCC
ISGAHWLGTDDLGRDILSRMIHGAPVTLYASLLAVGVAIVLGLPIGLLAGYLGGWLDEVV
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLIDTLLSFPAIVLAIAVTGALGIGLTNAMISVGIVFAPQLARIVRARTLVVKQELYVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARCFGASTRSILWRHVLPNTIQPVIVQITLLLAGALLAEASLSFLGLGIQPPNASWGAM
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LARAYQNMEIAPEQMYAPGLAILSTAIAFNTLGESLRVALDPTHQRL
HHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]