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The map label for this gene is pknK [H]

Identifier: 121609879

GI number: 121609879

Start: 3281536

End: 3284295

Strand: Direct

Name: pknK [H]

Synonym: Veis_2932

Alternate gene names: 121609879

Gene position: 3281536-3284295 (Clockwise)

Preceding gene: 121609878

Following gene: 121609880

Centisome position: 58.95

GC content: 70.76

Gene sequence:

>2760_bases
ATGAGCCGCAGTCTTGCGGTGCCGTCCGGGCGCAGGCCCGAACCGGTCGCCAGCGCCAAGCTGCTTGCGCCGCGCCCGCC
GCGCCGGCTGGTGCCGCGCGATGCGTTGCAGGCGCGGCTGCTGCAAGCCCGGCGCCAGCGCTGCGTGGTCGTGCAGGGGC
CCGCAGGCAGCGGCAAGACCAGCACGCTGGTGGCCTGGCGGCAGGCGCTGCTGGCGCTGGACTTCGACGTGGCCTGGCTG
TCCCTTTCGGCCGAGGATTGCGCGCCGGCACGCTTTTTCGACTGCCTGCTGGCGAGCATCGGCGCGATCGATCCCGATGC
GGTGCGCGAGGCGGCGCTCCTGCTCGGGCAGGGCAACGACGATTCGGCGCTCGAGCATGCCGTGATCACCGTCGTGCAGG
CCATCGCGTCGCGGCCACGGGAACTGGTGCTGATGCTCGACGATCTCCAGCACCTGCAAGACGCCCGCATCTTCCGGGCG
CTGCAGTGGCTGCTCGACTACGCGCCACCGAAACTGCACCTTGTCCTGACTTCGCGCAATGCCCTGCCGCTGTCGTTCGT
GCGGCTTCGTTCGCAAGGACTGGTGAGCGAATTCGACCTGCGCGACCTGCGCTTTTCCGCCGAAGAAACCGGGCGCTTCC
TGCGCGAGCGACTGGGCAGCATCGACCTGCGCGACATGCAGGCGCTGCACGAACTGACCGACGGCTGGGTGGCGGGCCTG
CAACTGTTCGTGCCCGGCTTGCAGGCCGGGCGGGGCGCCGCATACGCCCGGGCGCAGGCGCGTGATGCGCAGGTCTTTGC
GCGCTATTTCGAGCGCGAAGTGCTGGCGCATCTGGCGCATGAAGACCTGGCACTGCTCACCAGGATGGCTGTTTGCAACC
GTTTCAGTGCCTCCTTGTGCGCCGCGCTGATGGGGCAGCAGGATGCCGGCGGCATGGCGCTGCGGCTGGCGCGCCTGGAC
GGCGGGAACCTGTTCATCAGTCGGGTCGGCGGCCATGGCCGCGACGACTGGTACCGCGTGCATCCGCTCCTGCGGGAGAC
ACTGATGGCACGCTTGGAAAGACGCCCCGGCGCCGAGCGCCGCGCGCTGCATGGCGCGGCCTGGCGCTGGTTCGAAGCGC
ACGGGCATATCGGCGAGGTTGTGCGCCATGCCGTGCTGGCGGGCGACGCGCACGCGGCGGCGGACATCGTGCAGGCTTGC
GCGTCCGACCTGATGGCCCAGGGCGAACTGGCCGCGCTCGGCGGCCTGATGCGCAGATTGCCCGCAGCGCAGGTGCAGGC
GCGTCTTGCGCTGCGGCTGGCTGCGGCCTACCTGCATATGTACGCGCGCAACATCCAGGCGCTCGAGAGCGAACTGGCGC
AACTGCAGGCGCAGTGGGACAGCCTGGACATGCAGCAACACCACGATATGGCGCTGCTGCGCGGCGGCCTGGCCCTGCAG
CGCGACGACACCGAGGCGCTGCTGGCGCTCGCGCCGCAGCTTCGGGCCATCCCGGACGACAGGCCGCCCCTCTTTGCCGG
GCGCTGCCACCTGTTGGCCTGGATGCTGATGCACCGCGACGCATACGGCCAGGCCCGCGTGCTGCTGGACCAGGCCGCGC
AGCAACGAGGCAGCGCGCCGGCGCGTCGTCTGATCGGGCGCTGCTTGGCCGGCATGAGCTACGCGCTCGAAGGCCGCATG
ACCGAGGCCGAGCAACTGCTGCGCGAGGTTCTGCAAGAGGCGCAAGGGCAAGGCGCGGCCAGGATCGGGGTGGCCAGCAT
GGCGGCGGGCCTGCTGAGCGACATGCTCTACGAGTGCAACGAACTCGAAGCCGCCTGCAGCCTGCTCGAACCCCGCATCG
AAGTGCTCGAGCGCGCCTCGATTCCCGATGCGGTGCTGCGCGCCTTCGTCGTCTTGGCATGTGCGCACTGGCTGACGGGC
CGGCGCCTGCAAGCGCTCGGCCACCTCCAGCGCCTGGAAGACTACGCCGCGCGCAACGGGCTCGACCGCCTGCTCGCACA
TGCGCTACGGCTGCGCATGCGCCTGCACCTCAAGCAAGGCCAGACCATGCAGGCCGACATGGTGTTCGGGCGGATCGAGG
TGCTCGGCGCACGGCACGCCGGGGCCGGCAAGGGCACGGCAGCCGAGACCTGGCGCACCACCGAGCGCGCACGCGCCGAC
ATGCGCCTGCACTGGAACGACTTCGGCGCCGCCGTCGACTGCCTCGGAGCGCTCGTGCAGCGCACGGCTTCGGCCGGCCG
GCTGCGCACCCTGGCGGCCCTGCAGTTGCAACTGGCCGTTGCGGAATCGGGGCGCGGCAACCAGCAGGGCGCGCGCCACC
AGGCCATCGAAGCCCTGCGCCTGGGCCATCGGCTCGGGTTGGTGCGCAGCCTGCTGGACGTGTCGACGAACGTGCCAGCG
CTGCTCGATGCGCTGCTGGCGGATGCGGTGCCCGATCCGGTTCTCGCGTTCTATGCACGGCGGCTGCTGGATGCAGCCGC
AGCCACGCGGCGCATGGGTGCGGCCAGCGGCGGCGCAACGGACGCCGCAGCCGAAGGCAGCGCCGCCGATTTGCTCAACG
CGCGCGAGCGCGAGGTGCTCAGCCTCGTGGCGCAGGCCATGCCGAACAAGAAGATCGCTCGCGTGCTGGGCGTCACACCG
CACACCGTGAAGTGGCATCTGCGCAAGGTCTACAGCAAACTGGGCGTCGCCGAGCGCGGCGAAGCGGTCGCGCGCATGCG
CGATCTCGCGCTGCCTCGGGAAACCCCCAGGTCCCGCTGA

Upstream 100 bases:

>100_bases
TGCCGAATGGCGCAGCGCGCGCGCCTGACCGGCAGCGACGCGCCCGATACTGTGGGCCATCCCTTTTTCTTTTCCTTTTC
CCGCGCCCATGGGTGATGTC

Downstream 100 bases:

>100_bases
ACTGCGGCCAGTGTCGCGTCATCGGTCCGATGTCGCAGGCTGCGCGCAGCCATCGGAGCGCAGCGCAAGGCGCAGCGCGC
AGCCCATACCGAGCGTACTG

Product: regulatory protein LuxR

Products: NA

Alternate protein names: Protein kinase K [H]

Number of amino acids: Translated: 919; Mature: 918

Protein sequence:

>919_residues
MSRSLAVPSGRRPEPVASAKLLAPRPPRRLVPRDALQARLLQARRQRCVVVQGPAGSGKTSTLVAWRQALLALDFDVAWL
SLSAEDCAPARFFDCLLASIGAIDPDAVREAALLLGQGNDDSALEHAVITVVQAIASRPRELVLMLDDLQHLQDARIFRA
LQWLLDYAPPKLHLVLTSRNALPLSFVRLRSQGLVSEFDLRDLRFSAEETGRFLRERLGSIDLRDMQALHELTDGWVAGL
QLFVPGLQAGRGAAYARAQARDAQVFARYFEREVLAHLAHEDLALLTRMAVCNRFSASLCAALMGQQDAGGMALRLARLD
GGNLFISRVGGHGRDDWYRVHPLLRETLMARLERRPGAERRALHGAAWRWFEAHGHIGEVVRHAVLAGDAHAAADIVQAC
ASDLMAQGELAALGGLMRRLPAAQVQARLALRLAAAYLHMYARNIQALESELAQLQAQWDSLDMQQHHDMALLRGGLALQ
RDDTEALLALAPQLRAIPDDRPPLFAGRCHLLAWMLMHRDAYGQARVLLDQAAQQRGSAPARRLIGRCLAGMSYALEGRM
TEAEQLLREVLQEAQGQGAARIGVASMAAGLLSDMLYECNELEAACSLLEPRIEVLERASIPDAVLRAFVVLACAHWLTG
RRLQALGHLQRLEDYAARNGLDRLLAHALRLRMRLHLKQGQTMQADMVFGRIEVLGARHAGAGKGTAAETWRTTERARAD
MRLHWNDFGAAVDCLGALVQRTASAGRLRTLAALQLQLAVAESGRGNQQGARHQAIEALRLGHRLGLVRSLLDVSTNVPA
LLDALLADAVPDPVLAFYARRLLDAAAATRRMGAASGGATDAAAEGSAADLLNAREREVLSLVAQAMPNKKIARVLGVTP
HTVKWHLRKVYSKLGVAERGEAVARMRDLALPRETPRSR

Sequences:

>Translated_919_residues
MSRSLAVPSGRRPEPVASAKLLAPRPPRRLVPRDALQARLLQARRQRCVVVQGPAGSGKTSTLVAWRQALLALDFDVAWL
SLSAEDCAPARFFDCLLASIGAIDPDAVREAALLLGQGNDDSALEHAVITVVQAIASRPRELVLMLDDLQHLQDARIFRA
LQWLLDYAPPKLHLVLTSRNALPLSFVRLRSQGLVSEFDLRDLRFSAEETGRFLRERLGSIDLRDMQALHELTDGWVAGL
QLFVPGLQAGRGAAYARAQARDAQVFARYFEREVLAHLAHEDLALLTRMAVCNRFSASLCAALMGQQDAGGMALRLARLD
GGNLFISRVGGHGRDDWYRVHPLLRETLMARLERRPGAERRALHGAAWRWFEAHGHIGEVVRHAVLAGDAHAAADIVQAC
ASDLMAQGELAALGGLMRRLPAAQVQARLALRLAAAYLHMYARNIQALESELAQLQAQWDSLDMQQHHDMALLRGGLALQ
RDDTEALLALAPQLRAIPDDRPPLFAGRCHLLAWMLMHRDAYGQARVLLDQAAQQRGSAPARRLIGRCLAGMSYALEGRM
TEAEQLLREVLQEAQGQGAARIGVASMAAGLLSDMLYECNELEAACSLLEPRIEVLERASIPDAVLRAFVVLACAHWLTG
RRLQALGHLQRLEDYAARNGLDRLLAHALRLRMRLHLKQGQTMQADMVFGRIEVLGARHAGAGKGTAAETWRTTERARAD
MRLHWNDFGAAVDCLGALVQRTASAGRLRTLAALQLQLAVAESGRGNQQGARHQAIEALRLGHRLGLVRSLLDVSTNVPA
LLDALLADAVPDPVLAFYARRLLDAAAATRRMGAASGGATDAAAEGSAADLLNAREREVLSLVAQAMPNKKIARVLGVTP
HTVKWHLRKVYSKLGVAERGEAVARMRDLALPRETPRSR
>Mature_918_residues
SRSLAVPSGRRPEPVASAKLLAPRPPRRLVPRDALQARLLQARRQRCVVVQGPAGSGKTSTLVAWRQALLALDFDVAWLS
LSAEDCAPARFFDCLLASIGAIDPDAVREAALLLGQGNDDSALEHAVITVVQAIASRPRELVLMLDDLQHLQDARIFRAL
QWLLDYAPPKLHLVLTSRNALPLSFVRLRSQGLVSEFDLRDLRFSAEETGRFLRERLGSIDLRDMQALHELTDGWVAGLQ
LFVPGLQAGRGAAYARAQARDAQVFARYFEREVLAHLAHEDLALLTRMAVCNRFSASLCAALMGQQDAGGMALRLARLDG
GNLFISRVGGHGRDDWYRVHPLLRETLMARLERRPGAERRALHGAAWRWFEAHGHIGEVVRHAVLAGDAHAAADIVQACA
SDLMAQGELAALGGLMRRLPAAQVQARLALRLAAAYLHMYARNIQALESELAQLQAQWDSLDMQQHHDMALLRGGLALQR
DDTEALLALAPQLRAIPDDRPPLFAGRCHLLAWMLMHRDAYGQARVLLDQAAQQRGSAPARRLIGRCLAGMSYALEGRMT
EAEQLLREVLQEAQGQGAARIGVASMAAGLLSDMLYECNELEAACSLLEPRIEVLERASIPDAVLRAFVVLACAHWLTGR
RLQALGHLQRLEDYAARNGLDRLLAHALRLRMRLHLKQGQTMQADMVFGRIEVLGARHAGAGKGTAAETWRTTERARADM
RLHWNDFGAAVDCLGALVQRTASAGRLRTLAALQLQLAVAESGRGNQQGARHQAIEALRLGHRLGLVRSLLDVSTNVPAL
LDALLADAVPDPVLAFYARRLLDAAAATRRMGAASGGATDAAAEGSAADLLNAREREVLSLVAQAMPNKKIARVLGVTPH
TVKWHLRKVYSKLGVAERGEAVARMRDLALPRETPRSR

Specific function: Modulates the activity of transcription regulator virS via phosphorylation [H]

COG id: COG2909

COG function: function code K; ATP-dependent transcriptional regulator

Gene ontology:

Cell location: Cell membrane. Note=Probably attached to cell membrane through interactions mediated by its C- terminal region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Escherichia coli, GI2367223, Length=428, Percent_Identity=26.6355140186916, Blast_Score=104, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR016236
- InterPro:   IPR011990 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 100513; Mature: 100381

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSLAVPSGRRPEPVASAKLLAPRPPRRLVPRDALQARLLQARRQRCVVVQGPAGSGKT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCH
STLVAWRQALLALDFDVAWLSLSAEDCAPARFFDCLLASIGAIDPDAVREAALLLGQGND
HHHHHHHHHHHHHCCCHHHEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
DSALEHAVITVVQAIASRPRELVLMLDDLQHLQDARIFRALQWLLDYAPPKLHLVLTSRN
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
ALPLSFVRLRSQGLVSEFDLRDLRFSAEETGRFLRERLGSIDLRDMQALHELTDGWVAGL
CCCHHHHHHHHCCCHHHCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QLFVPGLQAGRGAAYARAQARDAQVFARYFEREVLAHLAHEDLALLTRMAVCNRFSASLC
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALMGQQDAGGMALRLARLDGGNLFISRVGGHGRDDWYRVHPLLRETLMARLERRPGAER
HHHHCCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
RALHGAAWRWFEAHGHIGEVVRHAVLAGDAHAAADIVQACASDLMAQGELAALGGLMRRL
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
PAAQVQARLALRLAAAYLHMYARNIQALESELAQLQAQWDSLDMQQHHDMALLRGGLALQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEE
RDDTEALLALAPQLRAIPDDRPPLFAGRCHLLAWMLMHRDAYGQARVLLDQAAQQRGSAP
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCH
ARRLIGRCLAGMSYALEGRMTEAEQLLREVLQEAQGQGAARIGVASMAAGLLSDMLYECN
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
ELEAACSLLEPRIEVLERASIPDAVLRAFVVLACAHWLTGRRLQALGHLQRLEDYAARNG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
LDRLLAHALRLRMRLHLKQGQTMQADMVFGRIEVLGARHAGAGKGTAAETWRTTERARAD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MRLHWNDFGAAVDCLGALVQRTASAGRLRTLAALQLQLAVAESGRGNQQGARHQAIEALR
CEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LGHRLGLVRSLLDVSTNVPALLDALLADAVPDPVLAFYARRLLDAAAATRRMGAASGGAT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DAAAEGSAADLLNAREREVLSLVAQAMPNKKIARVLGVTPHTVKWHLRKVYSKLGVAERG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHH
EAVARMRDLALPRETPRSR
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SRSLAVPSGRRPEPVASAKLLAPRPPRRLVPRDALQARLLQARRQRCVVVQGPAGSGKT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCH
STLVAWRQALLALDFDVAWLSLSAEDCAPARFFDCLLASIGAIDPDAVREAALLLGQGND
HHHHHHHHHHHHHCCCHHHEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
DSALEHAVITVVQAIASRPRELVLMLDDLQHLQDARIFRALQWLLDYAPPKLHLVLTSRN
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
ALPLSFVRLRSQGLVSEFDLRDLRFSAEETGRFLRERLGSIDLRDMQALHELTDGWVAGL
CCCHHHHHHHHCCCHHHCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QLFVPGLQAGRGAAYARAQARDAQVFARYFEREVLAHLAHEDLALLTRMAVCNRFSASLC
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALMGQQDAGGMALRLARLDGGNLFISRVGGHGRDDWYRVHPLLRETLMARLERRPGAER
HHHHCCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
RALHGAAWRWFEAHGHIGEVVRHAVLAGDAHAAADIVQACASDLMAQGELAALGGLMRRL
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
PAAQVQARLALRLAAAYLHMYARNIQALESELAQLQAQWDSLDMQQHHDMALLRGGLALQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEE
RDDTEALLALAPQLRAIPDDRPPLFAGRCHLLAWMLMHRDAYGQARVLLDQAAQQRGSAP
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCH
ARRLIGRCLAGMSYALEGRMTEAEQLLREVLQEAQGQGAARIGVASMAAGLLSDMLYECN
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
ELEAACSLLEPRIEVLERASIPDAVLRAFVVLACAHWLTGRRLQALGHLQRLEDYAARNG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
LDRLLAHALRLRMRLHLKQGQTMQADMVFGRIEVLGARHAGAGKGTAAETWRTTERARAD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MRLHWNDFGAAVDCLGALVQRTASAGRLRTLAALQLQLAVAESGRGNQQGARHQAIEALR
CEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LGHRLGLVRSLLDVSTNVPALLDALLADAVPDPVLAFYARRLLDAAAATRRMGAASGGAT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DAAAEGSAADLLNAREREVLSLVAQAMPNKKIARVLGVTPHTVKWHLRKVYSKLGVAERG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHH
EAVARMRDLALPRETPRSR
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]