BacMap

Definition	Verminephrobacter eiseniae EF01-2 chromosome, complete genome.
Accession	NC_008786
Length	5,566,749

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The map label for this gene is linC [H]

Identifier: 121609867

GI number: 121609867

Start: 3267688

End: 3268446

Strand: Direct

Name: linC [H]

Synonym: Veis_2920

Alternate gene names: 121609867

Gene position: 3267688-3268446 (Clockwise)

Preceding gene: 121609866

Following gene: 121609868

Centisome position: 58.7

GC content: 71.67

Gene sequence:

>759_bases
ATGAGCCTGCACGGCAAGACGGCCTTCGTCACCGGGGCCGGTTCGGGCATTGGCCAGGCCACGGCCATGGCGTTCGCGCA
GGCCGGCGCCTGGGTGCTGCTGGTCGATCGTGACGAAAGCGCATTGGCCGGCGCGCTGGCCGCGCTGCGCCAGGGCGGCG
GCCAGGGTGCGACGATGGTCTGCGATGTCCGACAGGGCGATGCGGTCCGCGCGGCCGTCGCCTGCGCCGTGCAGCAGCGC
GGCGCGCTGGACTGCGCCGTCAACGCGGCGGGCGTCGAAGGCGCCAGCAAGACCTTGCTGGACGAGGACGAAGCGCTGTT
CGAGCAGGTCATGGACATCAACCTGCGCGGGGTCTGGCACTGCCTGCGCGCCCAGATCGGGCAGATGCTGAGCCAGCGCG
CGGGCGGGGCCATCGTCAACATCGCTTCGGCAGCGGGGCTGGTCGGCTCCAGGCGCTGCGCCGCTTATTCGGCATCCAAG
CATGGCGTGCTGGGTTTGACGCGCAGCGCCGCATTGCAGTACGGCGGCCAGCGGGTCCGCATCAATGCCGTCTGCCCTGC
CGGCGTCAGCACCGACATGGCGCGCCGCATCGTCTCCTCGGCCGGCCAGGACATGGCCGGCGGCGGCCGCAACTACCCGT
TGGGCCGCTACAGCACGCCGCAGGAGATCGCCTCCGGCGCGCTGTGGCTCTGCTCCGAGGGCGCAGCCTCGACCACCGGC
GCCGTGCTGTCCATGGACTGCGGCTTTACTGCGGCATAG

Upstream 100 bases:

>100_bases
CGGTCAACTGGATGGACGGCCCGGAGTTTCAGCCGGTGATGAAGCGCGACATGGAACTGTGGCGCTCGCTGGTGCAGCGC
TCGGGCGTGGTGATCGAGCG

Downstream 100 bases:

>100_bases
ACGCGCAATACCTTCCGAAGGCCCCGCATGAGTTCCCGTTTGCTTTGCGCCACCTACTGGCGCGCCAGTTGGATCCGCTT
TCGCGAGCCCGTCGCCGCAT

Product: short-chain dehydrogenase/reductase SDR

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: 2,5-DDOL dehydrogenase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSLHGKTAFVTGAGSGIGQATAMAFAQAGAWVLLVDRDESALAGALAALRQGGGQGATMVCDVRQGDAVRAAVACAVQQR
GALDCAVNAAGVEGASKTLLDEDEALFEQVMDINLRGVWHCLRAQIGQMLSQRAGGAIVNIASAAGLVGSRRCAAYSASK
HGVLGLTRSAALQYGGQRVRINAVCPAGVSTDMARRIVSSAGQDMAGGGRNYPLGRYSTPQEIASGALWLCSEGAASTTG
AVLSMDCGFTAA

Sequences:

>Translated_252_residues
MSLHGKTAFVTGAGSGIGQATAMAFAQAGAWVLLVDRDESALAGALAALRQGGGQGATMVCDVRQGDAVRAAVACAVQQR
GALDCAVNAAGVEGASKTLLDEDEALFEQVMDINLRGVWHCLRAQIGQMLSQRAGGAIVNIASAAGLVGSRRCAAYSASK
HGVLGLTRSAALQYGGQRVRINAVCPAGVSTDMARRIVSSAGQDMAGGGRNYPLGRYSTPQEIASGALWLCSEGAASTTG
AVLSMDCGFTAA
>Mature_251_residues
SLHGKTAFVTGAGSGIGQATAMAFAQAGAWVLLVDRDESALAGALAALRQGGGQGATMVCDVRQGDAVRAAVACAVQQRG
ALDCAVNAAGVEGASKTLLDEDEALFEQVMDINLRGVWHCLRAQIGQMLSQRAGGAIVNIASAAGLVGSRRCAAYSASKH
GVLGLTRSAALQYGGQRVRINAVCPAGVSTDMARRIVSSAGQDMAGGGRNYPLGRYSTPQEIASGALWLCSEGAASTTGA
VLSMDCGFTAA

Specific function: Catalyzes the degradation of 2,5-dichloro-2,5- cyclohexadiene-1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ) [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=240, Percent_Identity=30, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI31542939, Length=256, Percent_Identity=33.984375, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=31.1475409836066, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI59889578, Length=213, Percent_Identity=29.1079812206573, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=30.1158301158301, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=33.9920948616601, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=31.496062992126, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI5031737, Length=239, Percent_Identity=28.4518828451883, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=29.8804780876494, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI4504505, Length=244, Percent_Identity=31.1475409836066, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=30.5699481865285, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=31.8681318681319, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=37.7142857142857, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4758504, Length=202, Percent_Identity=33.6633663366337, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI83715985, Length=180, Percent_Identity=36.1111111111111, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=26.9387755102041, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4503817, Length=196, Percent_Identity=31.6326530612245, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI142976729, Length=209, Percent_Identity=28.2296650717703, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=27.979274611399, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503301, Length=252, Percent_Identity=28.968253968254, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI40254986, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI210032110, Length=197, Percent_Identity=25.8883248730964, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=34.1085271317829, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=36.7816091954023, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=30.5220883534137, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=29.0836653386454, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=31.496062992126, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=28.6274509803922, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=30.5220883534137, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=26.5873015873016, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=29.3172690763052, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787526, Length=254, Percent_Identity=27.1653543307087, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789378, Length=243, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=30.8300395256917, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=32.9317269076305, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=30.1587301587302, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=30.0395256916996, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=33.6, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=31.2820512820513, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=28.7449392712551, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=28.3524904214559, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=24.4897959183673, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=246, Percent_Identity=27.2357723577236, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=194, Percent_Identity=30.4123711340206, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=248, Percent_Identity=27.8225806451613, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=30.9644670050761, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=199, Percent_Identity=31.6582914572864, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=29.7435897435897, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=249, Percent_Identity=26.9076305220884, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=249, Percent_Identity=28.9156626506024, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=30.3664921465969, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=202, Percent_Identity=33.1683168316832, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=244, Percent_Identity=27.0491803278689, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=239, Percent_Identity=27.6150627615063, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=23.6947791164659, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=196, Percent_Identity=29.0816326530612, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=249, Percent_Identity=26.9076305220884, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=249, Percent_Identity=27.3092369477912, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=26.5873015873016, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=246, Percent_Identity=25.609756097561, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=198, Percent_Identity=29.7979797979798, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=246, Percent_Identity=27.2357723577236, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=241, Percent_Identity=24.896265560166, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=252, Percent_Identity=28.1746031746032, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=217, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=217, Percent_Identity=25.3456221198157, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71997099, Length=220, Percent_Identity=25, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=203, Percent_Identity=29.064039408867, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=24.6031746031746, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=35.3174603174603, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=32.5301204819277, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=31.1023622047244, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=28.5140562248996, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=28.6821705426357, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=32.0158102766798, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=29.8449612403101, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=30.8300395256917, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737361, Length=201, Percent_Identity=34.3283582089552, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI18859837, Length=242, Percent_Identity=26.8595041322314, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640492, Length=198, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641232, Length=241, Percent_Identity=28.6307053941909, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281364892, Length=197, Percent_Identity=28.4263959390863, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281364494, Length=213, Percent_Identity=26.2910798122066, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24665243, Length=199, Percent_Identity=28.643216080402, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221331218, Length=199, Percent_Identity=28.643216080402, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21357673, Length=258, Percent_Identity=25.1937984496124, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 25450; Mature: 25319

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHGKTAFVTGAGSGIGQATAMAFAQAGAWVLLVDRDESALAGALAALRQGGGQGATMV
CCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEE
CDVRQGDAVRAAVACAVQQRGALDCAVNAAGVEGASKTLLDEDEALFEQVMDINLRGVWH
EECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCCCHHHHHHHHHCCCHHHHHH
CLRAQIGQMLSQRAGGAIVNIASAAGLVGSRRCAAYSASKHGVLGLTRSAALQYGGQRVR
HHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCHHHHCCCCCCCEEEEHHHHHHHCCCCEEE
INAVCPAGVSTDMARRIVSSAGQDMAGGGRNYPLGRYSTPQEIASGALWLCSEGAASTTG
EEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCCC
AVLSMDCGFTAA
EEEEECCCCCCC
>Mature Secondary Structure 
SLHGKTAFVTGAGSGIGQATAMAFAQAGAWVLLVDRDESALAGALAALRQGGGQGATMV
CCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEE
CDVRQGDAVRAAVACAVQQRGALDCAVNAAGVEGASKTLLDEDEALFEQVMDINLRGVWH
EECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCCCHHHHHHHHHCCCHHHHHH
CLRAQIGQMLSQRAGGAIVNIASAAGLVGSRRCAAYSASKHGVLGLTRSAALQYGGQRVR
HHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCHHHHCCCCCCCEEEEHHHHHHHCCCCEEE
INAVCPAGVSTDMARRIVSSAGQDMAGGGRNYPLGRYSTPQEIASGALWLCSEGAASTTG
EEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCCC
AVLSMDCGFTAA
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7515041; 12450824 [H]