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The map label for this gene is pabB [H]

Identifier: 121609784

GI number: 121609784

Start: 3186392

End: 3188191

Strand: Direct

Name: pabB [H]

Synonym: Veis_2835

Alternate gene names: 121609784

Gene position: 3186392-3188191 (Clockwise)

Preceding gene: 121609783

Following gene: 121609787

Centisome position: 57.24

GC content: 71.94

Gene sequence:

>1800_bases
TTGACGACTACCTCCCGCATCGACTTCACCCAGCCGCTGGACGGCCAGGCCGCGCGCCTGCGCCAAGCCTTTGGCAGGCC
GCGCCAACTGTTGCTGGCCCACACCCATGCCGACGTGCGCGCGGTGCTCGACGCCGTGCATGCCGCAGCGCAGCGCGGCC
ACTGGTGCGTGGGCTATCTGCGCTATGAGGCAGCGGCGGCGTTCGACACCGCCTTGCAAACCCACGCGGCCGATGGCCCG
CTGGCCTGGTTTGCCGTGCACGACGCTCCCATGCCCTGGCCGGATGACAATCTGCAGCAGCGGGCGGCCGACCCGGCACG
GGTGGAGTGGGCCGACGGCCCGGAGCGTGCCGCGTTTGACGCAGCGCTGGCCCGCATACAGCAGGCCATCAGCGCGGGCG
AGCTGTACCAGGTCAATTACACCGCCCCGCTCAGGGGCCGCTTGCAGGGCGCCGCCGAGGCGCTGTTTGCCGCGCTGCAA
CAGGCCCAGCCTGGCGGCTACGCGGCGCATATCGTTGCCGGGGATGAGCAGTTGCTGTCGGTGTCGCCCGAACTGTTCTT
CGACTGGCACGATGCGCCCGGCGGCGGCCGCATCGTGGCCCGCCCGATGAAAGGCACGGCCCCGCGCGGCGCCACGCCCG
GGCAGGACATGGCCAACGCCGAGTGGCTGCGCACGGCACCCAAGGAGCGGGCCGAGAACGTGATGATCGTCGACCTGCTG
CGCAACGACATGGCGCGCATCGCCCTGCCGCACAGCGTGCGCGTGCCGGTGCTGTTTGCCACGCAGGCTCTGCCCACGGT
GTGGCAGATGACCTCGGACGTGCAGGCGCGCACACGGCCGGGCACCACGCTGACCGATGTGTTTGCTGCGCTGTTTCCCT
GCGGTTCGGTCACCGGCGCGCCCAAGGTGCGCGCGATGCAGATGATCCGCCAACTCGAGCCTGCCCCGCGCGGTGTGTAC
TGCGGCGCCGTGGGCGTGGTGCGGCCTCGCGGCCCCGCCGGGGCCGATGGGCTGCGCGCCGTGGCCGCCACGTTCAACGT
GCCGATACGCACCGTGGTGCTGCATACGCAGGGCGGCCAGCAGCGCGTCCACTGCGGCATCGGCAGCGGCATCACCTGCG
GCGCGCAGGCCGATGCCGAGTGGCGCGAATGGCAGTACAAGCGCGCCTTCGTCGAGCGCGCCAGCATGCCGTTCGAACTG
CTGGAAACCCTGGCCCTGGAGGACGCAGCGTTTCGCCATCTGCCCGAGCACCTGGCCCGCCTGCGCGGCGCTGCGGCGCA
TTTCGGCGTGCCGTGGGATGCCGATGCCGTGCAGCAATGCCTGCGGGCGCTGGCGCAGCGCCACCTGGCGCAGCGCTGGC
GTGTGCGCCTGCTGCTGGACGCTGCGGGCCGGCCCCGGGCCGAGGCCTTTGCCCTGCACGCCGCATCGGAGCCGGTGCGC
CTGGCGCTGGCCACCCGGGCGTTCACGGCGGCGCACAGCGAGTTTGTGCGCTACAAGACGACGCGCCGCGCGCATTACGC
GGCTTTTGCGCCGACTGCGCCGGGGGTGTTCGACACGCTGCTGTGGAACGAGGCCGGCGAGATCACTGAAAGCACCTTCG
GCAACATCGCCGCATACATCGACGGCCGCTGGGTGACCCCGCCATGCTGCTGCGGCCTGCTGCCCGGCGTGGGCCGCGCC
GTGGCGCTGCGCGAAGGGCGCGTGGCAGAGGCCGTGCTGCGCCTGACCGACAGGCCCCGGGTACAGGGCTGGGCGTTCAT
CAACAGCCTGCGCGGGTGGCTGGCCGCCACGGTGCAGTAA

Upstream 100 bases:

>100_bases
TTGGCACCGACGGGCACAGCGCCTGGCGTTGCCGGTCAAGCCCCGAATGATTTGTAATCGATAGCTGCACGCGCTGTCAG
AACGAGCGCCAGGGCCTATC

Downstream 100 bases:

>100_bases
AACACCCCCGGCAGGCAAGCCAGCGCCAAACCGCCGCCAGCCGCACAGCATATGGCTGGGCAGGGCAGCCGGCACCAAGC
CCGCGCCCAGGCACCAAGCC

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MTTTSRIDFTQPLDGQAARLRQAFGRPRQLLLAHTHADVRAVLDAVHAAAQRGHWCVGYLRYEAAAAFDTALQTHAADGP
LAWFAVHDAPMPWPDDNLQQRAADPARVEWADGPERAAFDAALARIQQAISAGELYQVNYTAPLRGRLQGAAEALFAALQ
QAQPGGYAAHIVAGDEQLLSVSPELFFDWHDAPGGGRIVARPMKGTAPRGATPGQDMANAEWLRTAPKERAENVMIVDLL
RNDMARIALPHSVRVPVLFATQALPTVWQMTSDVQARTRPGTTLTDVFAALFPCGSVTGAPKVRAMQMIRQLEPAPRGVY
CGAVGVVRPRGPAGADGLRAVAATFNVPIRTVVLHTQGGQQRVHCGIGSGITCGAQADAEWREWQYKRAFVERASMPFEL
LETLALEDAAFRHLPEHLARLRGAAAHFGVPWDADAVQQCLRALAQRHLAQRWRVRLLLDAAGRPRAEAFALHAASEPVR
LALATRAFTAAHSEFVRYKTTRRAHYAAFAPTAPGVFDTLLWNEAGEITESTFGNIAAYIDGRWVTPPCCCGLLPGVGRA
VALREGRVAEAVLRLTDRPRVQGWAFINSLRGWLAATVQ

Sequences:

>Translated_599_residues
MTTTSRIDFTQPLDGQAARLRQAFGRPRQLLLAHTHADVRAVLDAVHAAAQRGHWCVGYLRYEAAAAFDTALQTHAADGP
LAWFAVHDAPMPWPDDNLQQRAADPARVEWADGPERAAFDAALARIQQAISAGELYQVNYTAPLRGRLQGAAEALFAALQ
QAQPGGYAAHIVAGDEQLLSVSPELFFDWHDAPGGGRIVARPMKGTAPRGATPGQDMANAEWLRTAPKERAENVMIVDLL
RNDMARIALPHSVRVPVLFATQALPTVWQMTSDVQARTRPGTTLTDVFAALFPCGSVTGAPKVRAMQMIRQLEPAPRGVY
CGAVGVVRPRGPAGADGLRAVAATFNVPIRTVVLHTQGGQQRVHCGIGSGITCGAQADAEWREWQYKRAFVERASMPFEL
LETLALEDAAFRHLPEHLARLRGAAAHFGVPWDADAVQQCLRALAQRHLAQRWRVRLLLDAAGRPRAEAFALHAASEPVR
LALATRAFTAAHSEFVRYKTTRRAHYAAFAPTAPGVFDTLLWNEAGEITESTFGNIAAYIDGRWVTPPCCCGLLPGVGRA
VALREGRVAEAVLRLTDRPRVQGWAFINSLRGWLAATVQ
>Mature_598_residues
TTTSRIDFTQPLDGQAARLRQAFGRPRQLLLAHTHADVRAVLDAVHAAAQRGHWCVGYLRYEAAAAFDTALQTHAADGPL
AWFAVHDAPMPWPDDNLQQRAADPARVEWADGPERAAFDAALARIQQAISAGELYQVNYTAPLRGRLQGAAEALFAALQQ
AQPGGYAAHIVAGDEQLLSVSPELFFDWHDAPGGGRIVARPMKGTAPRGATPGQDMANAEWLRTAPKERAENVMIVDLLR
NDMARIALPHSVRVPVLFATQALPTVWQMTSDVQARTRPGTTLTDVFAALFPCGSVTGAPKVRAMQMIRQLEPAPRGVYC
GAVGVVRPRGPAGADGLRAVAATFNVPIRTVVLHTQGGQQRVHCGIGSGITCGAQADAEWREWQYKRAFVERASMPFELL
ETLALEDAAFRHLPEHLARLRGAAAHFGVPWDADAVQQCLRALAQRHLAQRWRVRLLLDAAGRPRAEAFALHAASEPVRL
ALATRAFTAAHSEFVRYKTTRRAHYAAFAPTAPGVFDTLLWNEAGEITESTFGNIAAYIDGRWVTPPCCCGLLPGVGRAV
ALREGRVAEAVLRLTDRPRVQGWAFINSLRGWLAATVQ

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=275, Percent_Identity=34.5454545454545, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1787518, Length=223, Percent_Identity=33.6322869955157, Blast_Score=93, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320935, Length=266, Percent_Identity=31.9548872180451, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6324361, Length=295, Percent_Identity=27.7966101694915, Blast_Score=90, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 65104; Mature: 64973

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTSRIDFTQPLDGQAARLRQAFGRPRQLLLAHTHADVRAVLDAVHAAAQRGHWCVGYL
CCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEH
RYEAAAAFDTALQTHAADGPLAWFAVHDAPMPWPDDNLQQRAADPARVEWADGPERAAFD
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCEEEECCCCCHHHHH
AALARIQQAISAGELYQVNYTAPLRGRLQGAAEALFAALQQAQPGGYAAHIVAGDEQLLS
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHEE
VSPELFFDWHDAPGGGRIVARPMKGTAPRGATPGQDMANAEWLRTAPKERAENVMIVDLL
CCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCCEEEEHHH
RNDMARIALPHSVRVPVLFATQALPTVWQMTSDVQARTRPGTTLTDVFAALFPCGSVTGA
HCCHHHEECCCCCCCCEEEEHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHCCCCCCCC
PKVRAMQMIRQLEPAPRGVYCGAVGVVRPRGPAGADGLRAVAATFNVPIRTVVLHTQGGQ
CHHHHHHHHHHCCCCCCCEEECCEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCC
QRVHCGIGSGITCGAQADAEWREWQYKRAFVERASMPFELLETLALEDAAFRHLPEHLAR
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRGAAAHFGVPWDADAVQQCLRALAQRHLAQRWRVRLLLDAAGRPRAEAFALHAASEPVR
HHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHEEEECCCCCEE
LALATRAFTAAHSEFVRYKTTRRAHYAAFAPTAPGVFDTLLWNEAGEITESTFGNIAAYI
EHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCHHHHHHCCEEEEE
DGRWVTPPCCCGLLPGVGRAVALREGRVAEAVLRLTDRPRVQGWAFINSLRGWLAATVQ
CCCCCCCHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTTSRIDFTQPLDGQAARLRQAFGRPRQLLLAHTHADVRAVLDAVHAAAQRGHWCVGYL
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEH
RYEAAAAFDTALQTHAADGPLAWFAVHDAPMPWPDDNLQQRAADPARVEWADGPERAAFD
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCEEEECCCCCHHHHH
AALARIQQAISAGELYQVNYTAPLRGRLQGAAEALFAALQQAQPGGYAAHIVAGDEQLLS
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHEE
VSPELFFDWHDAPGGGRIVARPMKGTAPRGATPGQDMANAEWLRTAPKERAENVMIVDLL
CCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCCEEEEHHH
RNDMARIALPHSVRVPVLFATQALPTVWQMTSDVQARTRPGTTLTDVFAALFPCGSVTGA
HCCHHHEECCCCCCCCEEEEHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHCCCCCCCC
PKVRAMQMIRQLEPAPRGVYCGAVGVVRPRGPAGADGLRAVAATFNVPIRTVVLHTQGGQ
CHHHHHHHHHHCCCCCCCEEECCEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCC
QRVHCGIGSGITCGAQADAEWREWQYKRAFVERASMPFELLETLALEDAAFRHLPEHLAR
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRGAAAHFGVPWDADAVQQCLRALAQRHLAQRWRVRLLLDAAGRPRAEAFALHAASEPVR
HHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHEEEECCCCCEE
LALATRAFTAAHSEFVRYKTTRRAHYAAFAPTAPGVFDTLLWNEAGEITESTFGNIAAYI
EHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCHHHHHHCCEEEEE
DGRWVTPPCCCGLLPGVGRAVALREGRVAEAVLRLTDRPRVQGWAFINSLRGWLAATVQ
CCCCCCCHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]