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The map label for this gene is yfeR [H]

Identifier: 121609477

GI number: 121609477

Start: 2850736

End: 2851707

Strand: Direct

Name: yfeR [H]

Synonym: Veis_2521

Alternate gene names: 121609477

Gene position: 2850736-2851707 (Clockwise)

Preceding gene: 121609474

Following gene: 121609481

Centisome position: 51.21

GC content: 70.78

Gene sequence:

>972_bases
ATGGCCACCTTGTCCACGCCCTTGCCGCTGCGGGCGCTCACACTGCGCCAGTTGCAGTTCTTCTCGGTGCTGGTGGAAGA
AGGGCAGTTCGGCCGCGCAGCGAAGCGGCTGGCCATCACCCAGCCCGCGCTCAGCAACGCGATCAAGCAAATGGAAAAAC
TGCTCGGTGCCGAACTGCTCACGCGCACCACCCACCGCCTCGAACTCACGCCCGTGGGCGCCGAGGTGCTGGTGCGCACG
GATTTCCTGGTCCACTCTTTCGCGGTGGCGCTGCGCGACATCGAGGGCACGGTGCAGCGCGGCCGGGCCTTCGTGCGCAT
CGGCGTGATTCCCTCGGCCAGCGCGCGCGTCGCGGCGGCGGCGAGCGAGTTCCTGAAAACCGGCGAGCGGGAAGTGGAAC
TGGCTTGGCGCGACGCCCCCTCGACCGCGCTACTGGCCGAACTGCGCAGCGGCCAGCTCGACATGGCGGTGGCCGCCATC
ACCGAGCCGCCGGGCGGGCTGACCTGCATCGACCTGTTGCGCGATCCGCTGGTGCTGGTGGTGCGCCGCGACCATGCGCT
GGCGGCGGCGGGCGGAGCCACATGGGAGGCCATCGGCCGCGAGCGCCTCGTGCTGTTCGAAAGCGGCAGCATGCCGGCGC
TGGGCAACCCGGCGCGCGCGCAATTCGCGCAGGGTACCGAGCCCTGGCGCGTGAGCTATTCTGAAACGCTTTATGCGCTG
GTGCGAAGCGGGCAGGCGCTGGGGCTGATGCCGCGCCTGTACACCGCGCCGCTGCGCGATCCCGAGTTGGCGGTGGTGCC
CCTGCTCGAGCCGCGCATCGAACGCCGCGTGGTGCTGGCCTATCTGCCGGGGCCGATGCGCAACATGGTGGCGCAGGAAC
TGATCGCGTTCCTGCGCGAGCGGCTGCCGCAGGCGGGCCAAGCCACGGCGCGCCGCATGGCCAACGGCACGCGGACCAAG
CGCCAGGGCTAG

Upstream 100 bases:

>100_bases
GGCCGGCAGGGGTCATGCGCGCAGTCTAGGCAGACGCGGGACATAAGGAAAATTTTGAATTTCTATAATTTGATTCACTG
AGTCGATAACCGGAGCGCCC

Downstream 100 bases:

>100_bases
TCCACTGCATCATTGAATAAGCACCTGCCGAATGCGCCGTGATGGATCGTCGTACTTCCACTTGATGGGCTTGGGATTCT
TGTTGTGTTCGCGGATGTAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MATLSTPLPLRALTLRQLQFFSVLVEEGQFGRAAKRLAITQPALSNAIKQMEKLLGAELLTRTTHRLELTPVGAEVLVRT
DFLVHSFAVALRDIEGTVQRGRAFVRIGVIPSASARVAAAASEFLKTGEREVELAWRDAPSTALLAELRSGQLDMAVAAI
TEPPGGLTCIDLLRDPLVLVVRRDHALAAAGGATWEAIGRERLVLFESGSMPALGNPARAQFAQGTEPWRVSYSETLYAL
VRSGQALGLMPRLYTAPLRDPELAVVPLLEPRIERRVVLAYLPGPMRNMVAQELIAFLRERLPQAGQATARRMANGTRTK
RQG

Sequences:

>Translated_323_residues
MATLSTPLPLRALTLRQLQFFSVLVEEGQFGRAAKRLAITQPALSNAIKQMEKLLGAELLTRTTHRLELTPVGAEVLVRT
DFLVHSFAVALRDIEGTVQRGRAFVRIGVIPSASARVAAAASEFLKTGEREVELAWRDAPSTALLAELRSGQLDMAVAAI
TEPPGGLTCIDLLRDPLVLVVRRDHALAAAGGATWEAIGRERLVLFESGSMPALGNPARAQFAQGTEPWRVSYSETLYAL
VRSGQALGLMPRLYTAPLRDPELAVVPLLEPRIERRVVLAYLPGPMRNMVAQELIAFLRERLPQAGQATARRMANGTRTK
RQG
>Mature_322_residues
ATLSTPLPLRALTLRQLQFFSVLVEEGQFGRAAKRLAITQPALSNAIKQMEKLLGAELLTRTTHRLELTPVGAEVLVRTD
FLVHSFAVALRDIEGTVQRGRAFVRIGVIPSASARVAAAASEFLKTGEREVELAWRDAPSTALLAELRSGQLDMAVAAIT
EPPGGLTCIDLLRDPLVLVVRRDHALAAAGGATWEAIGRERLVLFESGSMPALGNPARAQFAQGTEPWRVSYSETLYALV
RSGQALGLMPRLYTAPLRDPELAVVPLLEPRIERRVVLAYLPGPMRNMVAQELIAFLRERLPQAGQATARRMANGTRTKR
QG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788748, Length=268, Percent_Identity=27.6119402985075, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=27.3972602739726, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693105, Length=267, Percent_Identity=25.8426966292135, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787879, Length=198, Percent_Identity=32.3232323232323, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081904, Length=175, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI2367136, Length=193, Percent_Identity=30.0518134715026, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789506, Length=260, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=24.3333333333333, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI157672245, Length=193, Percent_Identity=26.4248704663212, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35210; Mature: 35078

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLSTPLPLRALTLRQLQFFSVLVEEGQFGRAAKRLAITQPALSNAIKQMEKLLGAELL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TRTTHRLELTPVGAEVLVRTDFLVHSFAVALRDIEGTVQRGRAFVRIGVIPSASARVAAA
HHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
ASEFLKTGEREVELAWRDAPSTALLAELRSGQLDMAVAAITEPPGGLTCIDLLRDPLVLV
HHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHCCCEEEE
VRRDHALAAAGGATWEAIGRERLVLFESGSMPALGNPARAQFAQGTEPWRVSYSETLYAL
EECCCCEEECCCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCEECHHHHHHHH
VRSGQALGLMPRLYTAPLRDPELAVVPLLEPRIERRVVLAYLPGPMRNMVAQELIAFLRE
HHCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
RLPQAGQATARRMANGTRTKRQG
HCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATLSTPLPLRALTLRQLQFFSVLVEEGQFGRAAKRLAITQPALSNAIKQMEKLLGAELL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TRTTHRLELTPVGAEVLVRTDFLVHSFAVALRDIEGTVQRGRAFVRIGVIPSASARVAAA
HHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
ASEFLKTGEREVELAWRDAPSTALLAELRSGQLDMAVAAITEPPGGLTCIDLLRDPLVLV
HHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHCCCEEEE
VRRDHALAAAGGATWEAIGRERLVLFESGSMPALGNPARAQFAQGTEPWRVSYSETLYAL
EECCCCEEECCCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCEECHHHHHHHH
VRSGQALGLMPRLYTAPLRDPELAVVPLLEPRIERRVVLAYLPGPMRNMVAQELIAFLRE
HHCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
RLPQAGQATARRMANGTRTKRQG
HCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]