Click here to switch to the map view.

The map label for this gene is allR [H]

Identifier: 121609474

GI number: 121609474

Start: 2847712

End: 2848581

Strand: Direct

Name: allR [H]

Synonym: Veis_2518

Alternate gene names: 121609474

Gene position: 2847712-2848581 (Clockwise)

Preceding gene: 121609460

Following gene: 121609477

Centisome position: 51.16

GC content: 70.23

Gene sequence:

>870_bases
ATGCCGATACGTGAAGACGATCCGCAGCCGGCCCGCGTGGCAGGCAGCCAGGTGGTGCAGCGCATTGCGCTGCTGATGCG
GCTGGTCGCTGCGGGCCAACGCTCGGGCCTGCGCTTGGCGGACTTGTACCGCGCCGCAGACCTGGAGCGGCCCACGGTGC
ATCGATTGCTGCAATCACTGGTGGCCGAGCGTCTGCTGCGCCAGGACAGCCACACGCACCGCTATTTCCTCGGGCCTGCG
ATGTACGAGATGGGCCTGGCCGCCTCGCCCAAACTGGCGCTGCGCGACATCTGTCATCCGCACCTGCAGCGCATTGCCAA
ACTGACGGGCGACACCGTGTTCCTGACGGAGCGATCGGGCCTGGATGGGGTCTGCACCGACAGGGCCGAAGGCGATGCGC
CGATCAAGGTCTACGTGCTGGAGATCGGCCGGCGCCGGCCACTGACGGTGGGCGGCGGCTCTGCCGCCATCCTGAGCGCG
ATGGACGACGAGGAACTCAACCGCGTGTGCCGCGCCAACCTCGACCGCACGCTCAAGAAATTCCCGCGCTATTCCGAAGC
AGTCCTGCGCCGCTGCATCGGGCGCGGGCGCTCGCGCGGCTACATCGTGCGCGACCTGCTGGAGATTCCCGACGTGCGCA
CGGTGGCGCTGGCGCTCCGCGATCCGCGCGGTCTTCCGATGGCGGGCATCAGCGTATCGACCATCGCGCCCCGCCTCGGC
GATGAGCGCGCAGCGCAGGTGGCGGGCTGGATCCGCACGGCGGTCGATGCCATCGAAGCCGCGCTGGCCGCCTATGCTCC
GGGCGCCCACCGCGCCGGCGCATCGGCTCAGCCAGCGCCGCCGGGCGCCGGCCAGGCGCTCACTCCTTGA

Upstream 100 bases:

>100_bases
CCCGATTCTCCTTGCTGCCGGTATATGGACATTCCCGGCCCCATCGATCATAGGAAAGCCGGCGCTAAGATCACGCAATC
TCTCTTGCAAATGAGTCCAT

Downstream 100 bases:

>100_bases
TGTTGGCGCTCTGCACGATCTTCTGGTTGCGCGCGTACTCGGTCTGCACGAAGCGGCCGAAGTCCTCGGGCGTGCCGCTG
CCGGGCAGCGCGCCTTGCCC

Product: regulatory protein IclR

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MPIREDDPQPARVAGSQVVQRIALLMRLVAAGQRSGLRLADLYRAADLERPTVHRLLQSLVAERLLRQDSHTHRYFLGPA
MYEMGLAASPKLALRDICHPHLQRIAKLTGDTVFLTERSGLDGVCTDRAEGDAPIKVYVLEIGRRRPLTVGGGSAAILSA
MDDEELNRVCRANLDRTLKKFPRYSEAVLRRCIGRGRSRGYIVRDLLEIPDVRTVALALRDPRGLPMAGISVSTIAPRLG
DERAAQVAGWIRTAVDAIEAALAAYAPGAHRAGASAQPAPPGAGQALTP

Sequences:

>Translated_289_residues
MPIREDDPQPARVAGSQVVQRIALLMRLVAAGQRSGLRLADLYRAADLERPTVHRLLQSLVAERLLRQDSHTHRYFLGPA
MYEMGLAASPKLALRDICHPHLQRIAKLTGDTVFLTERSGLDGVCTDRAEGDAPIKVYVLEIGRRRPLTVGGGSAAILSA
MDDEELNRVCRANLDRTLKKFPRYSEAVLRRCIGRGRSRGYIVRDLLEIPDVRTVALALRDPRGLPMAGISVSTIAPRLG
DERAAQVAGWIRTAVDAIEAALAAYAPGAHRAGASAQPAPPGAGQALTP
>Mature_288_residues
PIREDDPQPARVAGSQVVQRIALLMRLVAAGQRSGLRLADLYRAADLERPTVHRLLQSLVAERLLRQDSHTHRYFLGPAM
YEMGLAASPKLALRDICHPHLQRIAKLTGDTVFLTERSGLDGVCTDRAEGDAPIKVYVLEIGRRRPLTVGGGSAAILSAM
DDEELNRVCRANLDRTLKKFPRYSEAVLRRCIGRGRSRGYIVRDLLEIPDVRTVALALRDPRGLPMAGISVSTIAPRLGD
ERAAQVAGWIRTAVDAIEAALAAYAPGAHRAGASAQPAPPGAGQALTP

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=267, Percent_Identity=26.2172284644195, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786468, Length=231, Percent_Identity=24.2424242424242, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082359, Length=225, Percent_Identity=22.2222222222222, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788131, Length=260, Percent_Identity=22.6923076923077, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 31308; Mature: 31176

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIREDDPQPARVAGSQVVQRIALLMRLVAAGQRSGLRLADLYRAADLERPTVHRLLQSL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
VAERLLRQDSHTHRYFLGPAMYEMGLAASPKLALRDICHPHLQRIAKLTGDTVFLTERSG
HHHHHHHCCCCCCEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCC
LDGVCTDRAEGDAPIKVYVLEIGRRRPLTVGGGSAAILSAMDDEELNRVCRANLDRTLKK
CCCCCCCCCCCCCCEEEEEEECCCCCCEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
FPRYSEAVLRRCIGRGRSRGYIVRDLLEIPDVRTVALALRDPRGLPMAGISVSTIAPRLG
CCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCC
DERAAQVAGWIRTAVDAIEAALAAYAPGAHRAGASAQPAPPGAGQALTP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PIREDDPQPARVAGSQVVQRIALLMRLVAAGQRSGLRLADLYRAADLERPTVHRLLQSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
VAERLLRQDSHTHRYFLGPAMYEMGLAASPKLALRDICHPHLQRIAKLTGDTVFLTERSG
HHHHHHHCCCCCCEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCC
LDGVCTDRAEGDAPIKVYVLEIGRRRPLTVGGGSAAILSAMDDEELNRVCRANLDRTLKK
CCCCCCCCCCCCCCEEEEEEECCCCCCEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
FPRYSEAVLRRCIGRGRSRGYIVRDLLEIPDVRTVALALRDPRGLPMAGISVSTIAPRLG
CCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCC
DERAAQVAGWIRTAVDAIEAALAAYAPGAHRAGASAQPAPPGAGQALTP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA