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The map label for this gene is 121609380

Identifier: 121609380

GI number: 121609380

Start: 2739305

End: 2740585

Strand: Direct

Name: 121609380

Synonym: Veis_2423

Alternate gene names: NA

Gene position: 2739305-2740585 (Clockwise)

Preceding gene: 121609379

Following gene: 121609381

Centisome position: 49.21

GC content: 51.44

Gene sequence:

>1281_bases
ATGAGCCGAATTGATGAGTTGATTGCCGAGCACTGTCCAAATGGCGTGGAGTTCAAGCCGCTTGGTGAGTGCATATCCAA
AAATCTTGGTGGCGGTACCCCCTCGCGTTCTGTTGCGAGCTATTGGGATGGTGATATTCCATGGGCTTCCGTTGGTGATC
TCTCCATTCCCGGAAACTTCATTCGCACAACACGATCTTTGATTACCAAAGACGGACTTAAGAACAGTCCAAGCAACGTT
ATACGTGCTGGCGATGTAATTGTTGCCGTCAAAATTTCCCCAGGAAAAATGAAAATTGCCGCAACGGACATTGCGATCAA
TCAAGACCTTCGCGGCCTGACGCTTCATGATTTCATCGACAGCAGTTTTCTCGTTTATTACTTTCAGACTTTTTCAATTA
TTGGAAATGGCACCATCGTCAAAGGCATCACGACCGACACACTTGAAAGAGTGAAAGTTCCTGTACCGCCGCTCGAAGTG
CAACGTGAAATTGTGAAAGTGCTGGACACTTTCACTGAACTGGAGGCGGAACTGGAGGCGGAACTGGAGGCGGAACTGGA
GGCGCGTCGGCGGCAGTACAAGTACTACCGCGACGCGCTGTTCAGTTTCGATGAGCGCATGAGCGGCGCAAGCAAGCAAG
CAAGCAAGCAAGCAAGCAAGCAAGCAAGCAAGCAAGCAATAAGTATAAGGTGGATGACCTTGAGTGAAGTCGGAAAATTC
ATGCGCGGACGCCGTTTCACCAAGGCTGACTATGTCGAGGACGGTGTGGGCTGCATTCACTACGGCGAGATTTACACCCA
CTACGGCACATCGGCGAATGAGGTGATTTCACACGTGCGCCCCGAAATGAAATCAGGCTTACGCTTTGCGAAACCGGGCG
ACGTGGTGGTCGCCGATGTGGGCGAAACCGTTGAGGATGTTGGCAAAGCTGTGGCGTGGATGGGCACTGACGACGTGGCT
ATTCACGATCACTGCTACGCCTTCCGCCATTCGATGAATCCGAAATTTGTGTCTTACTGCATGCAGACCACTTCGTTCAT
CTCCGAAAAGGCCAAATATGTGGCGCGCACCAAGGTCAACACATTACTAATCGACGGCTTTTCCAAGATTCGTATTCCCG
TTCCGCCGCTCGAAGAACAAGAGCGCATCGTTGCTATCCTCGATAAATTTGACGCGCTGGTAAGCGATATTTCTTTCGGC
CTGCCCGCCGAAATCAAGGCGCGTCGTCAGCAGTACGAGCATTACCGCGACCGGCTGCTCACTTTCAAGGAAGCCGCATG
A

Upstream 100 bases:

>100_bases
AATATCGTGCGCAGTTGGTCACCGAACCTTCCGAAGTCGAAGCAACGTATCTGGAAACGGTGAAACGCGCGCAGCGCAAG
ATTGAGGGTAAGAAAAAATC

Downstream 100 bases:

>100_bases
GCGAAGACCGCAAACCTTTCCGCTATGAGCCGATTGCGCTATCCAACGAGAGCACGGTTGTCGCCGAATTTCAGCCCGAT
GCGCCGAGCGTGCGCGAGGC

Product: restriction modification system DNA specificity subunit

Products: NA

Alternate protein names: S protein [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSRIDELIAEHCPNGVEFKPLGECISKNLGGGTPSRSVASYWDGDIPWASVGDLSIPGNFIRTTRSLITKDGLKNSPSNV
IRAGDVIVAVKISPGKMKIAATDIAINQDLRGLTLHDFIDSSFLVYYFQTFSIIGNGTIVKGITTDTLERVKVPVPPLEV
QREIVKVLDTFTELEAELEAELEAELEARRRQYKYYRDALFSFDERMSGASKQASKQASKQASKQAISIRWMTLSEVGKF
MRGRRFTKADYVEDGVGCIHYGEIYTHYGTSANEVISHVRPEMKSGLRFAKPGDVVVADVGETVEDVGKAVAWMGTDDVA
IHDHCYAFRHSMNPKFVSYCMQTTSFISEKAKYVARTKVNTLLIDGFSKIRIPVPPLEEQERIVAILDKFDALVSDISFG
LPAEIKARRQQYEHYRDRLLTFKEAA

Sequences:

>Translated_426_residues
MSRIDELIAEHCPNGVEFKPLGECISKNLGGGTPSRSVASYWDGDIPWASVGDLSIPGNFIRTTRSLITKDGLKNSPSNV
IRAGDVIVAVKISPGKMKIAATDIAINQDLRGLTLHDFIDSSFLVYYFQTFSIIGNGTIVKGITTDTLERVKVPVPPLEV
QREIVKVLDTFTELEAELEAELEAELEARRRQYKYYRDALFSFDERMSGASKQASKQASKQASKQAISIRWMTLSEVGKF
MRGRRFTKADYVEDGVGCIHYGEIYTHYGTSANEVISHVRPEMKSGLRFAKPGDVVVADVGETVEDVGKAVAWMGTDDVA
IHDHCYAFRHSMNPKFVSYCMQTTSFISEKAKYVARTKVNTLLIDGFSKIRIPVPPLEEQERIVAILDKFDALVSDISFG
LPAEIKARRQQYEHYRDRLLTFKEAA
>Mature_425_residues
SRIDELIAEHCPNGVEFKPLGECISKNLGGGTPSRSVASYWDGDIPWASVGDLSIPGNFIRTTRSLITKDGLKNSPSNVI
RAGDVIVAVKISPGKMKIAATDIAINQDLRGLTLHDFIDSSFLVYYFQTFSIIGNGTIVKGITTDTLERVKVPVPPLEVQ
REIVKVLDTFTELEAELEAELEAELEARRRQYKYYRDALFSFDERMSGASKQASKQASKQASKQAISIRWMTLSEVGKFM
RGRRFTKADYVEDGVGCIHYGEIYTHYGTSANEVISHVRPEMKSGLRFAKPGDVVVADVGETVEDVGKAVAWMGTDDVAI
HDHCYAFRHSMNPKFVSYCMQTTSFISEKAKYVARTKVNTLLIDGFSKIRIPVPPLEEQERIVAILDKFDALVSDISFGL
PAEIKARRQQYEHYRDRLLTFKEAA

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity [H]

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 47612; Mature: 47481

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIDELIAEHCPNGVEFKPLGECISKNLGGGTPSRSVASYWDGDIPWASVGDLSIPGNF
CCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHH
IRTTRSLITKDGLKNSPSNVIRAGDVIVAVKISPGKMKIAATDIAINQDLRGLTLHDFID
HHHHHHHHHHCCCCCCCCHHEEECCEEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHC
SSFLVYYFQTFSIIGNGTIVKGITTDTLERVKVPVPPLEVQREIVKVLDTFTELEAELEA
CCHHHHHHHHHHHHCCCEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELEAELEARRRQYKYYRDALFSFDERMSGASKQASKQASKQASKQAISIRWMTLSEVGKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEEEEHHHHHHH
MRGRRFTKADYVEDGVGCIHYGEIYTHYGTSANEVISHVRPEMKSGLRFAKPGDVVVADV
HHCCCCCCHHHHHCCCCEEEECHHHHCCCCCHHHHHHHHCHHHHCCCCCCCCCCEEEECC
GETVEDVGKAVAWMGTDDVAIHDHCYAFRHSMNPKFVSYCMQTTSFISEKAKYVARTKVN
HHHHHHHHHHEEECCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TLLIDGFSKIRIPVPPLEEQERIVAILDKFDALVSDISFGLPAEIKARRQQYEHYRDRLL
EEEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
TFKEAA
HHHCCC
>Mature Secondary Structure 
SRIDELIAEHCPNGVEFKPLGECISKNLGGGTPSRSVASYWDGDIPWASVGDLSIPGNF
CHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHH
IRTTRSLITKDGLKNSPSNVIRAGDVIVAVKISPGKMKIAATDIAINQDLRGLTLHDFID
HHHHHHHHHHCCCCCCCCHHEEECCEEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHC
SSFLVYYFQTFSIIGNGTIVKGITTDTLERVKVPVPPLEVQREIVKVLDTFTELEAELEA
CCHHHHHHHHHHHHCCCEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELEAELEARRRQYKYYRDALFSFDERMSGASKQASKQASKQASKQAISIRWMTLSEVGKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEEEEHHHHHHH
MRGRRFTKADYVEDGVGCIHYGEIYTHYGTSANEVISHVRPEMKSGLRFAKPGDVVVADV
HHCCCCCCHHHHHCCCCEEEECHHHHCCCCCHHHHHHHHCHHHHCCCCCCCCCCEEEECC
GETVEDVGKAVAWMGTDDVAIHDHCYAFRHSMNPKFVSYCMQTTSFISEKAKYVARTKVN
HHHHHHHHHHEEECCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TLLIDGFSKIRIPVPPLEEQERIVAILDKFDALVSDISFGLPAEIKARRQQYEHYRDRLL
EEEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
TFKEAA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]