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The map label for this gene is pyrF

Identifier: 120613327

GI number: 120613327

Start: 5239204

End: 5240028

Strand: Direct

Name: pyrF

Synonym: Aave_4696

Alternate gene names: 120613327

Gene position: 5239204-5240028 (Clockwise)

Preceding gene: 120613324

Following gene: 120613328

Centisome position: 97.88

GC content: 72.97

Gene sequence:

>825_bases
ATGACCTTCATCGACATGCTGCGCGGCGCCACCGCGCGCAACGACTCCCTGCTCTGCGTGGGCCTGGACCCCGAGCCATC
GCGCTTTCCCGCCGGCCTGCGCGGCGATGCCGGCCGCATCTACGACTTCTGCGCGGCGATCGTCGATGCCACGGCCGACC
TGGCCTGCGCCTTCAAGCCGCAGATCGCGTATTTCGCCGCCCACCGCGCGGAAGAGCAGCTCGAGCGCCTCATGCGGCAC
ATGCGCGCCACCGCTCCGCACGTGCCCGTGATCCTGGACGCCAAGCGCGGCGACATCGGCTCCACGGCCCAGCAGTACGC
GATCGAGGCCTTCGAGCGCTACGGCGCCGACGCGGTGACGCTCTCGCCCTTCATGGGCTTCGACTCGATCGAGCCCTACC
TGGCCTACCACGGCAAGGGCGCCTTCCTGCTGTGCCGCACGTCCAACCCGGGCGGCGACGACCTGCAGAGCCAGCGCCTG
GCGAGCGTGGACGGCCAGCCGCTGCTGTTCGAACACATCGCGCGGCAGGCCCAGGGGCCCTGGAACCGCAACGGCCAGCT
GGGCCTCGTGGTGGGCGCCACCTACCCGGCCGAGATCGAGCGCGTGCGCGCCCTCGCCCCGACGCTGCCGCTGCTCATCC
CGGGCGTGGGCGCCCAGGGCGGCGATGCGGCCGCCACGGTGCGCGCCGGGCTGCGGCCGGACGGCCCGGTCGTCGTGAAC
TCCTCGCGCGCCATCCTGTATGCGAGCGCGGACGAAGGCTTCGCCGCTGCGGCACGGCAGGCGGCGCAGGCCACGCGCGA
TGCGTTGAACGCAGCACGGGGCTGA

Upstream 100 bases:

>100_bases
TACGGGCATGGATGCGGATCGTATCGGGGAGGCGCAACCCGCGCAGTCGTGCGCGGCACCCGGCCCGGGGGCGCAGGGGG
CGCCCTCTACAATCCCGGCC

Downstream 100 bases:

>100_bases
ACGCAGCCGGGTGACGGCTGGCGCTGCCGGCATGCCCGCCCCGGAGCGCCTCGGGCGACTCCGCGGCGGCCGGACGCGGC
ACCCGCAGCGCTGGAGAACT

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTFIDMLRGATARNDSLLCVGLDPEPSRFPAGLRGDAGRIYDFCAAIVDATADLACAFKPQIAYFAAHRAEEQLERLMRH
MRATAPHVPVILDAKRGDIGSTAQQYAIEAFERYGADAVTLSPFMGFDSIEPYLAYHGKGAFLLCRTSNPGGDDLQSQRL
ASVDGQPLLFEHIARQAQGPWNRNGQLGLVVGATYPAEIERVRALAPTLPLLIPGVGAQGGDAAATVRAGLRPDGPVVVN
SSRAILYASADEGFAAAARQAAQATRDALNAARG

Sequences:

>Translated_274_residues
MTFIDMLRGATARNDSLLCVGLDPEPSRFPAGLRGDAGRIYDFCAAIVDATADLACAFKPQIAYFAAHRAEEQLERLMRH
MRATAPHVPVILDAKRGDIGSTAQQYAIEAFERYGADAVTLSPFMGFDSIEPYLAYHGKGAFLLCRTSNPGGDDLQSQRL
ASVDGQPLLFEHIARQAQGPWNRNGQLGLVVGATYPAEIERVRALAPTLPLLIPGVGAQGGDAAATVRAGLRPDGPVVVN
SSRAILYASADEGFAAAARQAAQATRDALNAARG
>Mature_273_residues
TFIDMLRGATARNDSLLCVGLDPEPSRFPAGLRGDAGRIYDFCAAIVDATADLACAFKPQIAYFAAHRAEEQLERLMRHM
RATAPHVPVILDAKRGDIGSTAQQYAIEAFERYGADAVTLSPFMGFDSIEPYLAYHGKGAFLLCRTSNPGGDDLQSQRLA
SVDGQPLLFEHIARQAQGPWNRNGQLGLVVGATYPAEIERVRALAPTLPLLIPGVGAQGGDAAATVRAGLRPDGPVVVNS
SRAILYASADEGFAAAARQAAQATRDALNAARG

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRF_ACIAC (A1TW93)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_973005.1
- STRING:   A1TW93
- GeneID:   4669041
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_4696
- NMPDR:   fig|397945.5.peg.4051
- eggNOG:   COG0284
- HOGENOM:   HBG348634
- OMA:   LLCRTSN
- ProtClustDB:   PRK00125
- BioCyc:   AAVE397945:AAVE_4696-MONOMER
- HAMAP:   MF_01215
- InterPro:   IPR013785
- InterPro:   IPR018089
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934
- TIGRFAMs:   TIGR02127

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.23

Molecular weight: Translated: 29077; Mature: 28946

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00156 OMPDECASE

Important sites: ACT_SITE 95-95

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFIDMLRGATARNDSLLCVGLDPEPSRFPAGLRGDAGRIYDFCAAIVDATADLACAFKP
CCHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCC
QIAYFAAHRAEEQLERLMRHMRATAPHVPVILDAKRGDIGSTAQQYAIEAFERYGADAVT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEE
LSPFMGFDSIEPYLAYHGKGAFLLCRTSNPGGDDLQSQRLASVDGQPLLFEHIARQAQGP
ECCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCC
WNRNGQLGLVVGATYPAEIERVRALAPTLPLLIPGVGAQGGDAAATVRAGLRPDGPVVVN
CCCCCCEEEEEECCCHHHHHHHHHHCCCCHHEECCCCCCCCCHHHHHCCCCCCCCCEEEC
SSRAILYASADEGFAAAARQAAQATRDALNAARG
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFIDMLRGATARNDSLLCVGLDPEPSRFPAGLRGDAGRIYDFCAAIVDATADLACAFKP
CHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCC
QIAYFAAHRAEEQLERLMRHMRATAPHVPVILDAKRGDIGSTAQQYAIEAFERYGADAVT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEE
LSPFMGFDSIEPYLAYHGKGAFLLCRTSNPGGDDLQSQRLASVDGQPLLFEHIARQAQGP
ECCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCC
WNRNGQLGLVVGATYPAEIERVRALAPTLPLLIPGVGAQGGDAAATVRAGLRPDGPVVVN
CCCCCCEEEEEECCCHHHHHHHHHHCCCCHHEECCCCCCCCCHHHHHCCCCCCCCCEEEC
SSRAILYASADEGFAAAARQAAQATRDALNAARG
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA