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The map label for this gene is fur [H]

Identifier: 120613188

GI number: 120613188

Start: 5073921

End: 5074358

Strand: Direct

Name: fur [H]

Synonym: Aave_4555

Alternate gene names: 120613188

Gene position: 5073921-5074358 (Clockwise)

Preceding gene: 120613183

Following gene: 120613192

Centisome position: 94.79

GC content: 63.01

Gene sequence:

>438_bases
ATGACGAACATCGACGAACTCAAGAGCACCGGGCTCAAGGCCACCCTGCCCCGCCTGAAGATCCTCGAGATCTTCCAGAA
AGGCGCACAACGCCACATGACGGCCGAAGACGTGTTCCGTGTGCTGCTGGACGAACGTTCCGACATCGGCCTGGCCACCG
TCTATCGCGTGCTCACCCAGTTCGAGCAGGCGGGCATCCTGATCCGCAGCAACTTCGAGAGCGGCAAGGCGGTGTACGAG
CTCAACGAGGGCCAGCACCACGACCACTTCATCTGCATGGTCTGCGGCAAGGTCGAGGAGTTCTTCGACCCCGAGATCGA
GAAGCGCCAGCAGCTCGTGGCCAAGGCCAAGGGATGGGTGGTGCAGGACCACTCGATGGCCCTCTACGGCCAATGCGCCA
GCTGCGCCGCGAAAGCCTCTTCCGGCAACGGCCGCTGA

Upstream 100 bases:

>100_bases
GACGGACATGGAAATTGGCATAAACGATATGATCGGACCATTGTAGCGGCTGGTCTCCCAGGCCTTGGCGCGCGCCCCTG
GCACACCGAAGGACCCTGTC

Downstream 100 bases:

>100_bases
CCGATTCACCCCTCTCTCAGGAGCCGTCCCGCTGCTCCATGGCGCGGCGGTGGCGCTCGACGAATTCCTGGTAGGTATCG
ATGCCGCGCAGGTTGAGGAT

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MTNIDELKSTGLKATLPRLKILEIFQKGAQRHMTAEDVFRVLLDERSDIGLATVYRVLTQFEQAGILIRSNFESGKAVYE
LNEGQHHDHFICMVCGKVEEFFDPEIEKRQQLVAKAKGWVVQDHSMALYGQCASCAAKASSGNGR

Sequences:

>Translated_145_residues
MTNIDELKSTGLKATLPRLKILEIFQKGAQRHMTAEDVFRVLLDERSDIGLATVYRVLTQFEQAGILIRSNFESGKAVYE
LNEGQHHDHFICMVCGKVEEFFDPEIEKRQQLVAKAKGWVVQDHSMALYGQCASCAAKASSGNGR
>Mature_144_residues
TNIDELKSTGLKATLPRLKILEIFQKGAQRHMTAEDVFRVLLDERSDIGLATVYRVLTQFEQAGILIRSNFESGKAVYEL
NEGQHHDHFICMVCGKVEEFFDPEIEKRQQLVAKAKGWVVQDHSMALYGQCASCAAKASSGNGR

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=127, Percent_Identity=55.9055118110236, Blast_Score=153, Evalue=5e-39,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16260; Mature: 16129

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNIDELKSTGLKATLPRLKILEIFQKGAQRHMTAEDVFRVLLDERSDIGLATVYRVLTQ
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
FEQAGILIRSNFESGKAVYELNEGQHHDHFICMVCGKVEEFFDPEIEKRQQLVAKAKGWV
HHHCCEEEEECCCCCCEEEEECCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHCCCE
VQDHSMALYGQCASCAAKASSGNGR
ECCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TNIDELKSTGLKATLPRLKILEIFQKGAQRHMTAEDVFRVLLDERSDIGLATVYRVLTQ
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
FEQAGILIRSNFESGKAVYELNEGQHHDHFICMVCGKVEEFFDPEIEKRQQLVAKAKGWV
HHHCCEEEEECCCCCCEEEEECCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHCCCE
VQDHSMALYGQCASCAAKASSGNGR
ECCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA