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The map label for this gene is exbB [H]

Identifier: 120613185

GI number: 120613185

Start: 5071618

End: 5072286

Strand: Reverse

Name: exbB [H]

Synonym: Aave_4552

Alternate gene names: 120613185

Gene position: 5072286-5071618 (Counterclockwise)

Preceding gene: 120613186

Following gene: 120613184

Centisome position: 94.76

GC content: 72.94

Gene sequence:

>669_bases
ATGAACGCGTGGCACTGGTGGCATCAGGGGGACATGGTCACCCGCATCTCGGCACTGCTGCTGCTGTCCATGTCCATCGC
GAGCTGGGTGGTCATCCTCTGGAAAGCGCGCCTGCTGCGGCGCGCCGTGGCCGGTGTGGAGCGGAGCACCGCGGAGTTCT
GGAGCTCGCCCACGCTGGCATCGGCGCGCGAGCGCCTGGTGCCGGCCGATCCCGACGGCCTCCTGCGGCCCCTGGTGGAC
GCCGCCACCGGCGTGGCGGACAACGCCCATGCCGGCTCGCTGGCCGCCAGCGGGCAGCGTTCCCAGCAGCTCACGCGTGT
CCTGCGCGATGCGCTGCACCGGGTCCTCGCACGCCTGGAGTTCGGGCAGGTGCTGCTGGCCACCGTAGGCTCCACGGCAC
CCTTCGTCGGCCTGCTCGGCACGGTCTGGGGCATCTACCATGCGCTCACGGCGCTGGCCGGCGGCGGGGCGGTATCGATC
GACCGCGTCGCCGGTCCGGTCGGCGAGGCGCTGGTGATGACGGCGGCGGGCCTGGCCGTGGCTATCCCCGCCGTGCTGGC
CTACAACCTGTTCGGGCGGTGGATCGGCCGCGTGGAAGCCGAGCTCGAAGGCTTCGCCCTCGACCTGCGCGAACTGCTCC
TGGACGGGCCGCCCTCCCGCGGCGGCTGA

Upstream 100 bases:

>100_bases
CGGCCTGCACGGCTGATCGCCTTCGACCGGCGCGGCCCGGTAGCGGCAGGTCCGCCCGCCCGCCCTTCCAGCCCTTCTCC
TTACTCTTGGTGGCGTATCC

Downstream 100 bases:

>100_bases
TCCACTGCCTTCAGCCCGCCCGCGACCCATGGCATTCGGCCGCCTCGAACGCACATCCGCCCCGAAGCCGATGAGCGACA
TCAACATGACGCCCCTGGTG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNAWHWWHQGDMVTRISALLLLSMSIASWVVILWKARLLRRAVAGVERSTAEFWSSPTLASARERLVPADPDGLLRPLVD
AATGVADNAHAGSLAASGQRSQQLTRVLRDALHRVLARLEFGQVLLATVGSTAPFVGLLGTVWGIYHALTALAGGGAVSI
DRVAGPVGEALVMTAAGLAVAIPAVLAYNLFGRWIGRVEAELEGFALDLRELLLDGPPSRGG

Sequences:

>Translated_222_residues
MNAWHWWHQGDMVTRISALLLLSMSIASWVVILWKARLLRRAVAGVERSTAEFWSSPTLASARERLVPADPDGLLRPLVD
AATGVADNAHAGSLAASGQRSQQLTRVLRDALHRVLARLEFGQVLLATVGSTAPFVGLLGTVWGIYHALTALAGGGAVSI
DRVAGPVGEALVMTAAGLAVAIPAVLAYNLFGRWIGRVEAELEGFALDLRELLLDGPPSRGG
>Mature_222_residues
MNAWHWWHQGDMVTRISALLLLSMSIASWVVILWKARLLRRAVAGVERSTAEFWSSPTLASARERLVPADPDGLLRPLVD
AATGVADNAHAGSLAASGQRSQQLTRVLRDALHRVLARLEFGQVLLATVGSTAPFVGLLGTVWGIYHALTALAGGGAVSI
DRVAGPVGEALVMTAAGLAVAIPAVLAYNLFGRWIGRVEAELEGFALDLRELLLDGPPSRGG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=220, Percent_Identity=31.3636363636364, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789381, Length=204, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 23527; Mature: 23527

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAWHWWHQGDMVTRISALLLLSMSIASWVVILWKARLLRRAVAGVERSTAEFWSSPTLA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SARERLVPADPDGLLRPLVDAATGVADNAHAGSLAASGQRSQQLTRVLRDALHRVLARLE
HHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
FGQVLLATVGSTAPFVGLLGTVWGIYHALTALAGGGAVSIDRVAGPVGEALVMTAAGLAV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCHHHHHHHHHHHHHHH
AIPAVLAYNLFGRWIGRVEAELEGFALDLRELLLDGPPSRGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNAWHWWHQGDMVTRISALLLLSMSIASWVVILWKARLLRRAVAGVERSTAEFWSSPTLA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SARERLVPADPDGLLRPLVDAATGVADNAHAGSLAASGQRSQQLTRVLRDALHRVLARLE
HHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
FGQVLLATVGSTAPFVGLLGTVWGIYHALTALAGGGAVSIDRVAGPVGEALVMTAAGLAV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCHHHHHHHHHHHHHHH
AIPAVLAYNLFGRWIGRVEAELEGFALDLRELLLDGPPSRGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]