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The map label for this gene is acdS

Identifier: 120613126

GI number: 120613126

Start: 4990700

End: 4991716

Strand: Direct

Name: acdS

Synonym: Aave_4493

Alternate gene names: 120613126

Gene position: 4990700-4991716 (Clockwise)

Preceding gene: 120613124

Following gene: 120613127

Centisome position: 93.24

GC content: 68.24

Gene sequence:

>1017_bases
ATGAACCTGCAGAAATTCCCCCGCCACGCCCTCACCTTCGGCCCCACGCCCATCCATCCCCTCAAGCGCCTGTCCGCGCA
CCTGGGCGGCAAGGTGGAGCTGTATGCCAAGCGCGAGGACTGCAATTCCGGCCTCGCCTTCGGCGGCAACAAGACCCGCA
AGCTGGAATACCTGATCCCCGAGGCGATCGAGGGCGGCTACGACACGCTGGTGTCCATCGGCGGCATCCAGTCCAACCAG
ACGCGGCAGGTGGCCGCGGTGGCCGCGCACCTGGGCATGAAGTGCGTGCTGGTGCAGGAGAACTGGGTGAACTACTCCGA
TGCGGTGTACGACCGCGTGGGCAACATCGAGATGTCGCGCATCATGGGCGCCGACGTGCGCCTGGACGCCGCGGGCTTCG
ACATCGGCATCCGCCCGAGCTGGGAGCAGGCCATGGAAGACGTGCGCCGCGCCGGCGGCAAGCCCTTCCCCATCCCCGCG
GGCTGCTCCGAGCATCCGCGCGGCGGCCTGGGCTTCGTGGCCTTCGCCGAGGAGGTGCGCCAGCAGGAGGAGGAACTGGG
CTTCCAGTTCGACTACATCGTCGTGTGCTCGGTCACCGGCAGCACGCAGGCCGGCATGGTGGTGGGCTTCGCGGCCGACG
GCCGGGCTGACCGCGTGATCGGCATCGACGCCTCCGCCAAGCCGGAGCAGACGCGCGAGCAGATCCTGCGCATCGCGCGC
AACACGGCGGAACTCGTGGAACTGGGCCGCGAGATCACCGATGCGGATGTCGTGCTCGACACGCGCTACGGCGGCCCCGA
ATACGGACTGCCCAACGAGGGCACGCTGGAAGCCATCCGCCTGTGCGCGCGGCAGGAAGGCATGCTCACCGATCCGGTGT
ACGAGGGCAAATCCATGCACGGGATGATCGACATGGTGCGCAACGGCGAATTCCCGGCAGGCTCTCGCGTGCTCTACGCC
CACCTGGGCGGCGTGCCGGCGCTCAACGCCTACAGCTTCCTGTTCCGCAACGGCTGA

Upstream 100 bases:

>100_bases
CCTACGATGCAGTCAACGGTGCACGGCCTCGCAGGCCACGCGCCGGACCTGGGCCCCGGCCCTCTCCCGCCTTTTTTCCG
CCCTCCCCGGCACCGCATCC

Downstream 100 bases:

>100_bases
ACGCCTGCCGCAGCCCGCGCCGTCCCACCGTTCCCCCACCGGAAGGAGCCCCGAAATGACGAAGTACCTGCCGGCGCTGC
GGCGCACCGGAGCCGCACTC

Product: 1-aminocyclopropane-1-carboxylate deaminase

Products: NA

Alternate protein names: ACC deaminase; ACCD

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNLQKFPRHALTFGPTPIHPLKRLSAHLGGKVELYAKREDCNSGLAFGGNKTRKLEYLIPEAIEGGYDTLVSIGGIQSNQ
TRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIEMSRIMGADVRLDAAGFDIGIRPSWEQAMEDVRRAGGKPFPIPA
GCSEHPRGGLGFVAFAEEVRQQEEELGFQFDYIVVCSVTGSTQAGMVVGFAADGRADRVIGIDASAKPEQTREQILRIAR
NTAELVELGREITDADVVLDTRYGGPEYGLPNEGTLEAIRLCARQEGMLTDPVYEGKSMHGMIDMVRNGEFPAGSRVLYA
HLGGVPALNAYSFLFRNG

Sequences:

>Translated_338_residues
MNLQKFPRHALTFGPTPIHPLKRLSAHLGGKVELYAKREDCNSGLAFGGNKTRKLEYLIPEAIEGGYDTLVSIGGIQSNQ
TRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIEMSRIMGADVRLDAAGFDIGIRPSWEQAMEDVRRAGGKPFPIPA
GCSEHPRGGLGFVAFAEEVRQQEEELGFQFDYIVVCSVTGSTQAGMVVGFAADGRADRVIGIDASAKPEQTREQILRIAR
NTAELVELGREITDADVVLDTRYGGPEYGLPNEGTLEAIRLCARQEGMLTDPVYEGKSMHGMIDMVRNGEFPAGSRVLYA
HLGGVPALNAYSFLFRNG
>Mature_338_residues
MNLQKFPRHALTFGPTPIHPLKRLSAHLGGKVELYAKREDCNSGLAFGGNKTRKLEYLIPEAIEGGYDTLVSIGGIQSNQ
TRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIEMSRIMGADVRLDAAGFDIGIRPSWEQAMEDVRRAGGKPFPIPA
GCSEHPRGGLGFVAFAEEVRQQEEELGFQFDYIVVCSVTGSTQAGMVVGFAADGRADRVIGIDASAKPEQTREQILRIAR
NTAELVELGREITDADVVLDTRYGGPEYGLPNEGTLEAIRLCARQEGMLTDPVYEGKSMHGMIDMVRNGEFPAGSRVLYA
HLGGVPALNAYSFLFRNG

Specific function: Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source

COG id: COG2515

COG function: function code E; 1-aminocyclopropane-1-carboxylate deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACC deaminase/D-cysteine desulfhydrase family

Homologues:

Organism=Escherichia coli, GI87082000, Length=330, Percent_Identity=36.969696969697, Blast_Score=190, Evalue=9e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 1A1D_ACIAC (A1TVP2)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_972804.1
- ProteinModelPortal:   A1TVP2
- SMR:   A1TVP2
- STRING:   A1TVP2
- GeneID:   4668326
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_4493
- NMPDR:   fig|397945.5.peg.3866
- eggNOG:   COG2515
- HOGENOM:   HBG689308
- OMA:   DIGIRPS
- ProtClustDB:   PRK12390
- BioCyc:   AAVE397945:AAVE_4493-MONOMER
- HAMAP:   MF_00807
- InterPro:   IPR005965
- InterPro:   IPR020601
- InterPro:   IPR001926
- TIGRFAMs:   TIGR01274

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =3.5.99.7

Molecular weight: Translated: 36806; Mature: 36806

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: ACT_SITE 78-78

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQKFPRHALTFGPTPIHPLKRLSAHLGGKVELYAKREDCNSGLAFGGNKTRKLEYLIP
CCCHHHCCHHEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCEECCCCCEEEEEECH
EAIEGGYDTLVSIGGIQSNQTRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIEMSR
HHHCCCHHHHEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCEEHHH
IMGADVRLDAAGFDIGIRPSWEQAMEDVRRAGGKPFPIPAGCSEHPRGGLGFVAFAEEVR
HCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
QQEEELGFQFDYIVVCSVTGSTQAGMVVGFAADGRADRVIGIDASAKPEQTREQILRIAR
HHHHHHCCEEEEEEEEEECCCCCCCEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHH
NTAELVELGREITDADVVLDTRYGGPEYGLPNEGTLEAIRLCARQEGMLTDPVYEGKSMH
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHH
GMIDMVRNGEFPAGSRVLYAHLGGVPALNAYSFLFRNG
HHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHEECC
>Mature Secondary Structure
MNLQKFPRHALTFGPTPIHPLKRLSAHLGGKVELYAKREDCNSGLAFGGNKTRKLEYLIP
CCCHHHCCHHEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCEECCCCCEEEEEECH
EAIEGGYDTLVSIGGIQSNQTRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIEMSR
HHHCCCHHHHEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCEEHHH
IMGADVRLDAAGFDIGIRPSWEQAMEDVRRAGGKPFPIPAGCSEHPRGGLGFVAFAEEVR
HCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
QQEEELGFQFDYIVVCSVTGSTQAGMVVGFAADGRADRVIGIDASAKPEQTREQILRIAR
HHHHHHCCEEEEEEEEEECCCCCCCEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHH
NTAELVELGREITDADVVLDTRYGGPEYGLPNEGTLEAIRLCARQEGMLTDPVYEGKSMH
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHH
GMIDMVRNGEFPAGSRVLYAHLGGVPALNAYSFLFRNG
HHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA