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The map label for this gene is nhaR [H]

Identifier: 120613098

GI number: 120613098

Start: 4960652

End: 4961542

Strand: Direct

Name: nhaR [H]

Synonym: Aave_4462

Alternate gene names: 120613098

Gene position: 4960652-4961542 (Clockwise)

Preceding gene: 120613094

Following gene: 120613103

Centisome position: 92.67

GC content: 70.71

Gene sequence:

>891_bases
ATGAGCCAGAGCTTCAACTATCGGCACCTCTACTACTTCTGGGTGGTCGCCAAGGAAGGCGGCGTGGCCCGCGCCGCCGA
GCGGCTCGACATGGCCGTGCAGACCATCAGCGCCCAGGTGCGCTCGCTGGAGAAAGACCTCGGCACCGCCCTGCTGCGCG
CCGAAGGCCGCAACCTCGTGCTCACCGACGCGGGCGTGGCCGCCATGCACGAGGCCGACCAGATCTTCGCCCTGGGCGAG
CAACTGCAGCACCGCGTGGCCGAAGCCGCCACCGGCCGCGTGCTGCGGCTGAACCTGGGGATCTCGGACGGCATCGCCAA
GGTGGCCGTGCACCGCCTGCTCACCCCCGTGCTGGACGCCCCCCACCTGCGCCTGCTGTGCCACGAGGGCGAATTCCAGC
CCCTGCTGGGGGAACTCGCCCTGCACAAGCTCGACGCCGTGCTGGCCGACCGCCCCGCCCCGCCCAACCCGGCCCTGAAG
ACCACCAGCCAGCTCCTGGGCACCAGCCCCATCGCCTGGTATGCCCCGCAGCAGTGGGCCGACGCCGCTGCCCGCGACTT
CCCCCACAGCCTCGCCGTCGTGCCCGTGCTGCTACCGACCGAACACGCCGCGGCCCGCGCCCGCATCGACCACTGGCTGG
AGCGGGAACGCATCCGGCCGCGGATTGCGGGGGAGTTCGAGGACAGCGCCCTACTGGCTACCTTTGCGAGCACCGGCATG
GGCGTGATGCCCGCGCCGGAGTCGATGGGGGAGCATCTGGGGCGCACGCACGGGCTGGTGGCGGTGGGGACGACGGCGGA
CGTGCAGGAGCAGTTTCACCTGATCTTCAGTGCGAGGAAGGTGATGCATCCGTTGGTGGTGCGGTTGGTGGAGGGAGGGA
CGCTGGATTGA

Upstream 100 bases:

>100_bases
AGTCCGGACTGTCAGGCCTGCAGGCGCGGAAAGGAAGATAGCCCGGCCGTAAGATCACTTCGGTTTTTTCGAACTGTTTC
GCTTCGTTGTCCTACAAAAC

Downstream 100 bases:

>100_bases
GAGGGATGCAGAGGACGGAATAACAGAACCAGCGCGCCCGCGAGACAACGAAGGAAAGAAAGCGCCGGATTCCGTCTTCG
GACGAGGTGAGCGGTGGGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSQSFNYRHLYYFWVVAKEGGVARAAERLDMAVQTISAQVRSLEKDLGTALLRAEGRNLVLTDAGVAAMHEADQIFALGE
QLQHRVAEAATGRVLRLNLGISDGIAKVAVHRLLTPVLDAPHLRLLCHEGEFQPLLGELALHKLDAVLADRPAPPNPALK
TTSQLLGTSPIAWYAPQQWADAAARDFPHSLAVVPVLLPTEHAAARARIDHWLERERIRPRIAGEFEDSALLATFASTGM
GVMPAPESMGEHLGRTHGLVAVGTTADVQEQFHLIFSARKVMHPLVVRLVEGGTLD

Sequences:

>Translated_296_residues
MSQSFNYRHLYYFWVVAKEGGVARAAERLDMAVQTISAQVRSLEKDLGTALLRAEGRNLVLTDAGVAAMHEADQIFALGE
QLQHRVAEAATGRVLRLNLGISDGIAKVAVHRLLTPVLDAPHLRLLCHEGEFQPLLGELALHKLDAVLADRPAPPNPALK
TTSQLLGTSPIAWYAPQQWADAAARDFPHSLAVVPVLLPTEHAAARARIDHWLERERIRPRIAGEFEDSALLATFASTGM
GVMPAPESMGEHLGRTHGLVAVGTTADVQEQFHLIFSARKVMHPLVVRLVEGGTLD
>Mature_295_residues
SQSFNYRHLYYFWVVAKEGGVARAAERLDMAVQTISAQVRSLEKDLGTALLRAEGRNLVLTDAGVAAMHEADQIFALGEQ
LQHRVAEAATGRVLRLNLGISDGIAKVAVHRLLTPVLDAPHLRLLCHEGEFQPLLGELALHKLDAVLADRPAPPNPALKT
TSQLLGTSPIAWYAPQQWADAAARDFPHSLAVVPVLLPTEHAAARARIDHWLERERIRPRIAGEFEDSALLATFASTGMG
VMPAPESMGEHLGRTHGLVAVGTTADVQEQFHLIFSARKVMHPLVVRLVEGGTLD

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=298, Percent_Identity=30.5369127516779, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1788297, Length=275, Percent_Identity=29.8181818181818, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32239; Mature: 32108

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSFNYRHLYYFWVVAKEGGVARAAERLDMAVQTISAQVRSLEKDLGTALLRAEGRNLV
CCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LTDAGVAAMHEADQIFALGEQLQHRVAEAATGRVLRLNLGISDGIAKVAVHRLLTPVLDA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
PHLRLLCHEGEFQPLLGELALHKLDAVLADRPAPPNPALKTTSQLLGTSPIAWYAPQQWA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCHHHH
DAAARDFPHSLAVVPVLLPTEHAAARARIDHWLERERIRPRIAGEFEDSALLATFASTGM
HHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
GVMPAPESMGEHLGRTHGLVAVGTTADVQEQFHLIFSARKVMHPLVVRLVEGGTLD
CCCCCCHHHHHHCCHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SQSFNYRHLYYFWVVAKEGGVARAAERLDMAVQTISAQVRSLEKDLGTALLRAEGRNLV
CCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LTDAGVAAMHEADQIFALGEQLQHRVAEAATGRVLRLNLGISDGIAKVAVHRLLTPVLDA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
PHLRLLCHEGEFQPLLGELALHKLDAVLADRPAPPNPALKTTSQLLGTSPIAWYAPQQWA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCHHHH
DAAARDFPHSLAVVPVLLPTEHAAARARIDHWLERERIRPRIAGEFEDSALLATFASTGM
HHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
GVMPAPESMGEHLGRTHGLVAVGTTADVQEQFHLIFSARKVMHPLVVRLVEGGTLD
CCCCCCHHHHHHCCHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]