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The map label for this gene is flhA [H]

Identifier: 120613049

GI number: 120613049

Start: 4906766

End: 4908847

Strand: Direct

Name: flhA [H]

Synonym: Aave_4413

Alternate gene names: 120613049

Gene position: 4906766-4908847 (Clockwise)

Preceding gene: 120613048

Following gene: 120613050

Centisome position: 91.67

GC content: 68.35

Gene sequence:

>2082_bases
ATGAAGACCCCCACGATCGCCTCCGCCCGCCAGTGGGCCGGCACTAATGTCTCCGCGCTGCAGGGCCTGTCGGCCCCGCT
GCTGGTGGTGGCCATCCTGGCGCTGATGGTGCTGCCCATCCCTGCCTGGCTGCTGGACACCTTCTTCACGCTCAACATCG
CCGTGGCGCTGATGGTGATGATGGTGGCGGCCTACATGCTGCGGCCTCTGGACTTCGCGGCATTCCCCTCCGTGCTGCTG
CTCACCACCCTGATGCGGCTGTCGCTGAACGTGGCCTCCACCCGCGTGGTGCTGCTGGAGGGCCACACCGGCCCCGGCGC
CGCCGGCGCGGTGATCGAGGCCTTCGGCCACTTCCTGATCGGCGGGAACTTCGCGGTGGGCCTGATCGTGTTCGCCATCC
TGGTGGTGATCAACTTCGTGGTGGTGACCAAGGGCGCCGAGCGCATCGCCGAAGTTTCCGCACGCTTCACGCTGGACGCC
ATGCCCGGCAAGCAGATGGCGGTGGACGCCGACCTGAACGCCGGCCTGATCGACGAGAAGGAGGCCAAGCGCCGCCGCGC
CGAGGTGCAGGAGGAAGCGAACTTCTTCGGCTCGATGGACGGCGCCTCGAAGTTCGTGCGCGGCGATGCCGTCGCCGGCA
TCCTGATCCTGCTCATCAACATCGTGGGCGGCTTCGCCATCGGCATGCTGCAGCACGACCTGTCCGCAGGGCAGGCCGCC
AACAGCTACATCCTGCTGGCCGTCGGCGACGCGCTGGTGGCGCAGATTCCCGGCCTGCTGATCTCGGTGGCCGCCGCCAT
GGTGGTCTCGCGCGTGGGCAAGGACCAGGACATGGGCCGCCAGATCGTGCAGCAGCTCTTCATGTCGCCGCGCGTGCTGG
GCGTGGCCGCCGCGATCCTGATCATGCTCGGCCTGATTCCCGGCATGCCGCACGCCGTGTTCCTGGTGATGGGCAGCGGC
CTCGGCTATGCCGCCTGGCTGCTGCACCAGCGCGCGAACGCGCCCAAGCCGGTGGAAGCGCCGCCCGCCCCCGCGGGCGA
CGGGGAGGCGAGCTGGGACGACCTGCAGCCGGTGGACCTGCTGGGCCTGGAGCTGGGCTACCGGCTGATCTCCCTGGTGG
ACAAGAGCCGCCAGGGCGACCTGCTGACCCGCATCAAGGGGGTGCGCCGCAAGTTCGCCCAGGAAGTAGGCTTCCTTCCC
CCGGCGGTGCACGTGCGCGACAACCTCGAGCTCAAGCCCAGCGCCTATCGCATCACGCTGCGCGGCGTGGTGGTGGGCGA
GGGCGAGGCGTTCCCGGGCATGTTCCTGGCGATCAACCCCGGCGGCATCAGCACGCCGCTCATCGGCACGCCCACCACCG
ACCCGGCATTCGGCCTGCCCGCCCACTGGATCGACGACCACCAGAAGGAAGCCGCACAAATGGCGGGTTTTACGGTCGTT
GATTCCGAAACCGTGATGGCCACCCATTTGTCACACTTGATGCAAGTCCAGGCCGCCAAGCTCCTGAGCCGCACCGAAAC
GCAGCAGCTCGTGGAACACGTCGGCAAATTGGCCCCCAAGCTCATCGAGGAAGTGGTTCCGAAAATGGTGTCGATCGCAA
CGTTCCAGAAGGTGCTCCAGCTGCTGCTGGAAGAGTCCGTGCACATCCGGGACATCCGCACCATCATCGAAACCCTCGCC
GAGCATGCGGGCGCCATCGGCGATCCGGTGGAGCTGGCGCGCCGCGTGCGCATCGCCCTCTCGCCGGCCATCGTGCAGCA
GATCTACGGCCCGACCCGCGAGCTCAACGTGATCGCGATCGAGCCGGGCCTGGAGCGCCTGCTGGTGCAGGCCCTGGGCA
ACGCCGCCGGCCCCTCGCTCGACCCGGGCGTGGCCGACATCCTCACGCAGAAGGCCGCGGAAGTGGCCATGCGGCAGGAA
GAGATGGGCATGCCCGCCTGCCTGCTGGTGCCCGACGCCATCCGCAACGCCGTCTCGCGCCTCGTGCGCCGGGTCGCCCC
GCGCCTGCAGGTGCTCGCCCACAGCGAGATCCCTGAAACCCACACCATCCGCATTGGCCCGATCCTCAAAGGTGCAGCAT
GA

Upstream 100 bases:

>100_bases
GCCGCATGCCCGACGCCCAACCCGATCCCTACGTGCCGCCGGAGCTCGATCCGCTCACGAAGGCCGCCCCATCCGACGCT
TCCGCTGCAGGTGACGCGCC

Downstream 100 bases:

>100_bases
ATATCAAACGCTTTACCGCTCCCACCTCCCGTGAGGCCCTGGCCAAGGCACGCATGGCCTTCGGAGACGGCACGCTGATC
CTCTCGAACCGCCAGATCGC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MKTPTIASARQWAGTNVSALQGLSAPLLVVAILALMVLPIPAWLLDTFFTLNIAVALMVMMVAAYMLRPLDFAAFPSVLL
LTTLMRLSLNVASTRVVLLEGHTGPGAAGAVIEAFGHFLIGGNFAVGLIVFAILVVINFVVVTKGAERIAEVSARFTLDA
MPGKQMAVDADLNAGLIDEKEAKRRRAEVQEEANFFGSMDGASKFVRGDAVAGILILLINIVGGFAIGMLQHDLSAGQAA
NSYILLAVGDALVAQIPGLLISVAAAMVVSRVGKDQDMGRQIVQQLFMSPRVLGVAAAILIMLGLIPGMPHAVFLVMGSG
LGYAAWLLHQRANAPKPVEAPPAPAGDGEASWDDLQPVDLLGLELGYRLISLVDKSRQGDLLTRIKGVRRKFAQEVGFLP
PAVHVRDNLELKPSAYRITLRGVVVGEGEAFPGMFLAINPGGISTPLIGTPTTDPAFGLPAHWIDDHQKEAAQMAGFTVV
DSETVMATHLSHLMQVQAAKLLSRTETQQLVEHVGKLAPKLIEEVVPKMVSIATFQKVLQLLLEESVHIRDIRTIIETLA
EHAGAIGDPVELARRVRIALSPAIVQQIYGPTRELNVIAIEPGLERLLVQALGNAAGPSLDPGVADILTQKAAEVAMRQE
EMGMPACLLVPDAIRNAVSRLVRRVAPRLQVLAHSEIPETHTIRIGPILKGAA

Sequences:

>Translated_693_residues
MKTPTIASARQWAGTNVSALQGLSAPLLVVAILALMVLPIPAWLLDTFFTLNIAVALMVMMVAAYMLRPLDFAAFPSVLL
LTTLMRLSLNVASTRVVLLEGHTGPGAAGAVIEAFGHFLIGGNFAVGLIVFAILVVINFVVVTKGAERIAEVSARFTLDA
MPGKQMAVDADLNAGLIDEKEAKRRRAEVQEEANFFGSMDGASKFVRGDAVAGILILLINIVGGFAIGMLQHDLSAGQAA
NSYILLAVGDALVAQIPGLLISVAAAMVVSRVGKDQDMGRQIVQQLFMSPRVLGVAAAILIMLGLIPGMPHAVFLVMGSG
LGYAAWLLHQRANAPKPVEAPPAPAGDGEASWDDLQPVDLLGLELGYRLISLVDKSRQGDLLTRIKGVRRKFAQEVGFLP
PAVHVRDNLELKPSAYRITLRGVVVGEGEAFPGMFLAINPGGISTPLIGTPTTDPAFGLPAHWIDDHQKEAAQMAGFTVV
DSETVMATHLSHLMQVQAAKLLSRTETQQLVEHVGKLAPKLIEEVVPKMVSIATFQKVLQLLLEESVHIRDIRTIIETLA
EHAGAIGDPVELARRVRIALSPAIVQQIYGPTRELNVIAIEPGLERLLVQALGNAAGPSLDPGVADILTQKAAEVAMRQE
EMGMPACLLVPDAIRNAVSRLVRRVAPRLQVLAHSEIPETHTIRIGPILKGAA
>Mature_693_residues
MKTPTIASARQWAGTNVSALQGLSAPLLVVAILALMVLPIPAWLLDTFFTLNIAVALMVMMVAAYMLRPLDFAAFPSVLL
LTTLMRLSLNVASTRVVLLEGHTGPGAAGAVIEAFGHFLIGGNFAVGLIVFAILVVINFVVVTKGAERIAEVSARFTLDA
MPGKQMAVDADLNAGLIDEKEAKRRRAEVQEEANFFGSMDGASKFVRGDAVAGILILLINIVGGFAIGMLQHDLSAGQAA
NSYILLAVGDALVAQIPGLLISVAAAMVVSRVGKDQDMGRQIVQQLFMSPRVLGVAAAILIMLGLIPGMPHAVFLVMGSG
LGYAAWLLHQRANAPKPVEAPPAPAGDGEASWDDLQPVDLLGLELGYRLISLVDKSRQGDLLTRIKGVRRKFAQEVGFLP
PAVHVRDNLELKPSAYRITLRGVVVGEGEAFPGMFLAINPGGISTPLIGTPTTDPAFGLPAHWIDDHQKEAAQMAGFTVV
DSETVMATHLSHLMQVQAAKLLSRTETQQLVEHVGKLAPKLIEEVVPKMVSIATFQKVLQLLLEESVHIRDIRTIIETLA
EHAGAIGDPVELARRVRIALSPAIVQQIYGPTRELNVIAIEPGLERLLVQALGNAAGPSLDPGVADILTQKAAEVAMRQE
EMGMPACLLVPDAIRNAVSRLVRRVAPRLQVLAHSEIPETHTIRIGPILKGAA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=695, Percent_Identity=54.5323741007194, Blast_Score=725, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 73799; Mature: 73799

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPTIASARQWAGTNVSALQGLSAPLLVVAILALMVLPIPAWLLDTFFTLNIAVALMVM
CCCCCCCCHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
MVAAYMLRPLDFAAFPSVLLLTTLMRLSLNVASTRVVLLEGHTGPGAAGAVIEAFGHFLI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHC
GGNFAVGLIVFAILVVINFVVVTKGAERIAEVSARFTLDAMPGKQMAVDADLNAGLIDEK
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCEEEECCCCCCCCCHH
EAKRRRAEVQEEANFFGSMDGASKFVRGDAVAGILILLINIVGGFAIGMLQHDLSAGQAA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NSYILLAVGDALVAQIPGLLISVAAAMVVSRVGKDQDMGRQIVQQLFMSPRVLGVAAAIL
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
IMLGLIPGMPHAVFLVMGSGLGYAAWLLHQRANAPKPVEAPPAPAGDGEASWDDLQPVDL
HHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LGLELGYRLISLVDKSRQGDLLTRIKGVRRKFAQEVGFLPPAVHVRDNLELKPSAYRITL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEEE
RGVVVGEGEAFPGMFLAINPGGISTPLIGTPTTDPAFGLPAHWIDDHQKEAAQMAGFTVV
EEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHCCCEEE
DSETVMATHLSHLMQVQAAKLLSRTETQQLVEHVGKLAPKLIEEVVPKMVSIATFQKVLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLEESVHIRDIRTIIETLAEHAGAIGDPVELARRVRIALSPAIVQQIYGPTRELNVIAI
HHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
EPGLERLLVQALGNAAGPSLDPGVADILTQKAAEVAMRQEEMGMPACLLVPDAIRNAVSR
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHH
LVRRVAPRLQVLAHSEIPETHTIRIGPILKGAA
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MKTPTIASARQWAGTNVSALQGLSAPLLVVAILALMVLPIPAWLLDTFFTLNIAVALMVM
CCCCCCCCHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
MVAAYMLRPLDFAAFPSVLLLTTLMRLSLNVASTRVVLLEGHTGPGAAGAVIEAFGHFLI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHC
GGNFAVGLIVFAILVVINFVVVTKGAERIAEVSARFTLDAMPGKQMAVDADLNAGLIDEK
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCEEEECCCCCCCCCHH
EAKRRRAEVQEEANFFGSMDGASKFVRGDAVAGILILLINIVGGFAIGMLQHDLSAGQAA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NSYILLAVGDALVAQIPGLLISVAAAMVVSRVGKDQDMGRQIVQQLFMSPRVLGVAAAIL
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
IMLGLIPGMPHAVFLVMGSGLGYAAWLLHQRANAPKPVEAPPAPAGDGEASWDDLQPVDL
HHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LGLELGYRLISLVDKSRQGDLLTRIKGVRRKFAQEVGFLPPAVHVRDNLELKPSAYRITL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEEE
RGVVVGEGEAFPGMFLAINPGGISTPLIGTPTTDPAFGLPAHWIDDHQKEAAQMAGFTVV
EEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHCCCEEE
DSETVMATHLSHLMQVQAAKLLSRTETQQLVEHVGKLAPKLIEEVVPKMVSIATFQKVLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLEESVHIRDIRTIIETLAEHAGAIGDPVELARRVRIALSPAIVQQIYGPTRELNVIAI
HHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
EPGLERLLVQALGNAAGPSLDPGVADILTQKAAEVAMRQEEMGMPACLLVPDAIRNAVSR
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHH
LVRRVAPRLQVLAHSEIPETHTIRIGPILKGAA
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]