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The map label for this gene is rna [C]

Identifier: 120611843

GI number: 120611843

Start: 3514951

End: 3515736

Strand: Direct

Name: rna [C]

Synonym: Aave_3184

Alternate gene names: 120611843

Gene position: 3514951-3515736 (Clockwise)

Preceding gene: 120611842

Following gene: 120611844

Centisome position: 65.67

GC content: 66.03

Gene sequence:

>786_bases
ATGCGCGGTCGGTCACGGCTTTCATTGTGGGCTTGCGCCCTGCTCTTCTGCGGGCTGGCTACCCTCGCCCCACCCGGCTC
CGCGCAAGAAGTATGCGCCGTCCCGGGTACCGTATCGGCCGCCCCTCCCCGCCCGGTGGACCACGCCAATCCACGGGCTC
CCACGGACTACCTGGCGCTGGTGCTGTCCTGGTCCCCCGAACACTGCGAAAGCCAGCGCAACAAGACCGGAGCGGCGAAG
GACCGGCATGCCTTCCAGTGCTTTTCCGGCAACCGGTTCGAATGGGTCGTGCACGGCCTGTGGCCGCAGAACGGCAAGGC
CCGGTCCGTGGACGACCATCCGCGCAATTGCCAGCCCACCCCCACAGCCCTGCCGGCGCCGCTGGTGCGGCAATACCTCT
GCATGATGCCTGGCACCGATCTGATGCAGAACGAGTGGCAGGCGCATGGCACCTGCGGCTGGGCATCGGCGGACCGGTAT
TTCGCGGATATCCAGCGCGTGTATGGCGCACTGCGCAGGCCCACCACGGCGCAGATGGTGCCGGGCGGAACCAGCGCGGG
GCCGAACCAGTTGCTGGATACCCGGGTTGCGGACGTGAAGCTGGCCTTTCTGGCACTCAATCCTCAACTGCAGGCGGAGA
ACCTGCGGGTGAATGTGGCTTCCGGCAATCGGCTGAAGGAAATTTGGATTTGCCTGGACAAGGGGTTAAAGCCTATGGCC
TGCCCTGTGGGAGGGACGCCGGATGGGCAGAGGATTCGACTGAGGACACCGGGGCAGCAGGGATGA

Upstream 100 bases:

>100_bases
GTGCTCCACCTGTTGACAATTGGTTCCAGCGCGCCATAGTTGAGCCCATTCAAAAAGGCGACGCCCCAGTTCAGAGGTCG
CGCGCCACAAGGAGGGATCC

Downstream 100 bases:

>100_bases
TGGCGGGAGCATTCTTCGCTTGGTTGCTAGGTTGTCCGCACTCCATAGCAAACCCAATTGATGCAAAGAACTGTGTATGG
CAACTGCGGCTTTGTAGCGG

Product: ribonuclease T2

Products: 3'- Phosphomononucleotides; 3'-Phosphooligonucleotides [C]

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MRGRSRLSLWACALLFCGLATLAPPGSAQEVCAVPGTVSAAPPRPVDHANPRAPTDYLALVLSWSPEHCESQRNKTGAAK
DRHAFQCFSGNRFEWVVHGLWPQNGKARSVDDHPRNCQPTPTALPAPLVRQYLCMMPGTDLMQNEWQAHGTCGWASADRY
FADIQRVYGALRRPTTAQMVPGGTSAGPNQLLDTRVADVKLAFLALNPQLQAENLRVNVASGNRLKEIWICLDKGLKPMA
CPVGGTPDGQRIRLRTPGQQG

Sequences:

>Translated_261_residues
MRGRSRLSLWACALLFCGLATLAPPGSAQEVCAVPGTVSAAPPRPVDHANPRAPTDYLALVLSWSPEHCESQRNKTGAAK
DRHAFQCFSGNRFEWVVHGLWPQNGKARSVDDHPRNCQPTPTALPAPLVRQYLCMMPGTDLMQNEWQAHGTCGWASADRY
FADIQRVYGALRRPTTAQMVPGGTSAGPNQLLDTRVADVKLAFLALNPQLQAENLRVNVASGNRLKEIWICLDKGLKPMA
CPVGGTPDGQRIRLRTPGQQG
>Mature_261_residues
MRGRSRLSLWACALLFCGLATLAPPGSAQEVCAVPGTVSAAPPRPVDHANPRAPTDYLALVLSWSPEHCESQRNKTGAAK
DRHAFQCFSGNRFEWVVHGLWPQNGKARSVDDHPRNCQPTPTALPAPLVRQYLCMMPGTDLMQNEWQAHGTCGWASADRY
FADIQRVYGALRRPTTAQMVPGGTSAGPNQLLDTRVADVKLAFLALNPQLQAENLRVNVASGNRLKEIWICLDKGLKPMA
CPVGGTPDGQRIRLRTPGQQG

Specific function: One Of The Few RNAses That Cleaves The Phosphodiester Bond Between Any Two Nucleotide. Shows A Preference For Cytidylic Or Guanylic Acid. [C]

COG id: COG3719

COG function: function code J; Ribonuclease I

Gene ontology:

Cell location: Periplasmic Protein And Cytoplasm. [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase T2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001568
- InterPro:   IPR018188 [H]

Pfam domain/function: PF00445 Ribonuclease_T2 [H]

EC number: 3.1.27.6 [C]

Molecular weight: Translated: 28426; Mature: 28426

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS00530 RNASE_T2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGRSRLSLWACALLFCGLATLAPPGSAQEVCAVPGTVSAAPPRPVDHANPRAPTDYLAL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHEEE
VLSWSPEHCESQRNKTGAAKDRHAFQCFSGNRFEWVVHGLWPQNGKARSVDDHPRNCQPT
EEECCHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
PTALPAPLVRQYLCMMPGTDLMQNEWQAHGTCGWASADRYFADIQRVYGALRRPTTAQMV
CCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEC
PGGTSAGPNQLLDTRVADVKLAFLALNPQLQAENLRVNVASGNRLKEIWICLDKGLKPMA
CCCCCCCHHHHHHHHHHHEEEEEEEECCCEECCCEEEEECCCCCHHHHHHHHHCCCCCEE
CPVGGTPDGQRIRLRTPGQQG
CCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MRGRSRLSLWACALLFCGLATLAPPGSAQEVCAVPGTVSAAPPRPVDHANPRAPTDYLAL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHEEE
VLSWSPEHCESQRNKTGAAKDRHAFQCFSGNRFEWVVHGLWPQNGKARSVDDHPRNCQPT
EEECCHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
PTALPAPLVRQYLCMMPGTDLMQNEWQAHGTCGWASADRYFADIQRVYGALRRPTTAQMV
CCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEC
PGGTSAGPNQLLDTRVADVKLAFLALNPQLQAENLRVNVASGNRLKEIWICLDKGLKPMA
CCCCCCCHHHHHHHHHHHEEEEEEEECCCEECCCEEEEECCCCCHHHHHHHHHCCCCCEE
CPVGGTPDGQRIRLRTPGQQG
CCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Nucleotides [C]

Specific reaction: Endonucleolytic Cleavage With 2',3'-Cyclic Phosphate Intermediates. [C]

General reaction: Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]