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The map label for this gene is ldcA [H]

Identifier: 120611741

GI number: 120611741

Start: 3396805

End: 3397707

Strand: Reverse

Name: ldcA [H]

Synonym: Aave_3081

Alternate gene names: 120611741

Gene position: 3397707-3396805 (Counterclockwise)

Preceding gene: 120611742

Following gene: 120611740

Centisome position: 63.48

GC content: 70.76

Gene sequence:

>903_bases
GTGCGCGACAAGGCCGCGTTCAAGCGCGGCGTCGCCCGCCTGCAGGCCATGGGGCACGAGGTGGAGGTGGATGCGGATGC
GCTGGCCGTCCATACCCGTTTCGCGGGCGATGACGCCACCCGCCTCGCTGCCATCCACCGCGCCGCCGCGAGCGGCGCCG
ACGTGGCGCTCATCTCGCGCGGAGGCTACGGGCTCACCCGCATCCTGGACGGCATCCGCTACAAGGCCGTGGCCAAGGCG
GTGGAGCGGGGCACGCAGTTCGTGGGCCTGAGCGATTTCACCGCCTTCCAGGCCGCGCTGCTCGCGAAGACCGGCGCCAT
GACCTGGGCCGGTCCGGCACTGGTCGGCGACCTGGGCTGCGAAGGCGAGCCCGACGACATCATGCTGGCCTGCCTGGACG
ACCTGCTCACCGGCCACGGCGAGGGCGCGGGATGGCGCATGCACAACGAGAAACCCGCCGCCGACGGAACGCCCGCGGTG
AAGGACTGCTACATCCGCAACGCCACGCTCTGGGGCGGCAACCTCGCCATGCTCTGCTCCCTGGTGGGCACGCCCTACCT
GCCCCAGGTCAAGGGCGGGATCCTGTTCGTGGAAGACGTGAGCGAGCATCCCTACCGTGTGGAGCGCATGCTCACGCAGC
TGCTGCACGCCGGCATCCTGGCGCAGCAGAAGGCGGTCGTGCTCGGGCAGTTCACCGGCTACCAGCTCGCGCCGCACGAC
AAGGGCTTCAAGCTGCAGACCGTGGTGGACTGGCTGCGCACCCGCATCAAGGCGCCCGTGCTCACCAACCTGCCGTTCGG
CCACGTGCCCACCAAGGTGCTGCTGCCGGTGGGCACGCCGGTCTCCCTCTCCGTGGAGGGGCGCGATGCCCTGATCTACT
GGGGCCACGCCGCCGGCCACTGA

Upstream 100 bases:

>100_bases
GACGGCCCGACGAGCCTTGTCCGAACACGATCACGACCATTCGCATTGCGGCCACGACCATGGCCCGCGCCACATCTACA
TCTATTCGCCGGCCGGTGCC

Downstream 100 bases:

>100_bases
GCACCGCCCATGAGAACCGTCCGGCACACCGTCGTGTTTTCCGACATCGTCGGCACCACGGCGCTGTTCGAGGCGCAGGG
CAACACCCTGGCCACCACGG

Product: muramoyltetrapeptide carboxypeptidase

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MRDKAAFKRGVARLQAMGHEVEVDADALAVHTRFAGDDATRLAAIHRAAASGADVALISRGGYGLTRILDGIRYKAVAKA
VERGTQFVGLSDFTAFQAALLAKTGAMTWAGPALVGDLGCEGEPDDIMLACLDDLLTGHGEGAGWRMHNEKPAADGTPAV
KDCYIRNATLWGGNLAMLCSLVGTPYLPQVKGGILFVEDVSEHPYRVERMLTQLLHAGILAQQKAVVLGQFTGYQLAPHD
KGFKLQTVVDWLRTRIKAPVLTNLPFGHVPTKVLLPVGTPVSLSVEGRDALIYWGHAAGH

Sequences:

>Translated_300_residues
MRDKAAFKRGVARLQAMGHEVEVDADALAVHTRFAGDDATRLAAIHRAAASGADVALISRGGYGLTRILDGIRYKAVAKA
VERGTQFVGLSDFTAFQAALLAKTGAMTWAGPALVGDLGCEGEPDDIMLACLDDLLTGHGEGAGWRMHNEKPAADGTPAV
KDCYIRNATLWGGNLAMLCSLVGTPYLPQVKGGILFVEDVSEHPYRVERMLTQLLHAGILAQQKAVVLGQFTGYQLAPHD
KGFKLQTVVDWLRTRIKAPVLTNLPFGHVPTKVLLPVGTPVSLSVEGRDALIYWGHAAGH
>Mature_300_residues
MRDKAAFKRGVARLQAMGHEVEVDADALAVHTRFAGDDATRLAAIHRAAASGADVALISRGGYGLTRILDGIRYKAVAKA
VERGTQFVGLSDFTAFQAALLAKTGAMTWAGPALVGDLGCEGEPDDIMLACLDDLLTGHGEGAGWRMHNEKPAADGTPAV
KDCYIRNATLWGGNLAMLCSLVGTPYLPQVKGGILFVEDVSEHPYRVERMLTQLLHAGILAQQKAVVLGQFTGYQLAPHD
KGFKLQTVVDWLRTRIKAPVLTNLPFGHVPTKVLLPVGTPVSLSVEGRDALIYWGHAAGH

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=275, Percent_Identity=40.3636363636364, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 32038; Mature: 32038

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDKAAFKRGVARLQAMGHEVEVDADALAVHTRFAGDDATRLAAIHRAAASGADVALISR
CCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEC
GGYGLTRILDGIRYKAVAKAVERGTQFVGLSDFTAFQAALLAKTGAMTWAGPALVGDLGC
CCCCHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCCCCCHHEECCCC
EGEPDDIMLACLDDLLTGHGEGAGWRMHNEKPAADGTPAVKDCYIRNATLWGGNLAMLCS
CCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHEEECCEEECCCHHHHHH
LVGTPYLPQVKGGILFVEDVSEHPYRVERMLTQLLHAGILAQQKAVVLGQFTGYQLAPHD
HHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEECCCC
KGFKLQTVVDWLRTRIKAPVLTNLPFGHVPTKVLLPVGTPVSLSVEGRDALIYWGHAAGH
CCCCHHHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCCCEEEEECCCEEEEEECCCCCC
>Mature Secondary Structure
MRDKAAFKRGVARLQAMGHEVEVDADALAVHTRFAGDDATRLAAIHRAAASGADVALISR
CCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEC
GGYGLTRILDGIRYKAVAKAVERGTQFVGLSDFTAFQAALLAKTGAMTWAGPALVGDLGC
CCCCHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCCCCCHHEECCCC
EGEPDDIMLACLDDLLTGHGEGAGWRMHNEKPAADGTPAVKDCYIRNATLWGGNLAMLCS
CCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHEEECCEEECCCHHHHHH
LVGTPYLPQVKGGILFVEDVSEHPYRVERMLTQLLHAGILAQQKAVVLGQFTGYQLAPHD
HHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEECCCC
KGFKLQTVVDWLRTRIKAPVLTNLPFGHVPTKVLLPVGTPVSLSVEGRDALIYWGHAAGH
CCCCHHHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCCCEEEEECCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]