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The map label for this gene is tctD [H]

Identifier: 120611675

GI number: 120611675

Start: 3321935

End: 3322711

Strand: Direct

Name: tctD [H]

Synonym: Aave_3012

Alternate gene names: 120611675

Gene position: 3321935-3322711 (Clockwise)

Preceding gene: 120611671

Following gene: 120611676

Centisome position: 62.06

GC content: 72.33

Gene sequence:

>777_bases
ATGCGCCCGCTTCCTGTCAAACGGCTGTCCGCCGACTCAGGGAAAACACCCATGGGGGCCACGGGCGTGCCCGGTGCTAT
GGTGCCGCGCATGCAATTGCTTCTCGTGGAAGACGACCCCGCCATGCAGGCCACGCTGCAGCGTTCGCTCGCGCGCCGCG
GCATGGAGGTGACCGCCCTCGGTGACGGCCGGGCCGCGCTGGCGCAGTGGGCGTCGCGCCCGCCCGATGCCGTGGTGCTG
GACCTGACGCTGCCCGGGCTGGACGGCCTGCAGGTGCTGCAGCAGGCGCGCGCCCGGGGCCTGCGCACGCCGGTGCTGCT
GCTCACCGCCCGGGGCACCGTGGGCGACCGGGTGCTGGGGCTCAATGCCGGCGCCGACGACTACCTGCCCAAGCCGTTCG
ACCTGGACGAACTGGAGGCGCGCCTGCGTGCGCTGGTGCGCCGGCTGGGCGACCTGTCGGAAGCGCGGCCGCCGGCGCCC
TCCACCGTGTCCATCGGAGCGATCCGCTACGAGAAGGACAGCGGCGCCATCTACCGCGACGGCGAGGTGATGGAGCTGAC
GCCGCGCGAGTTGGCCCTCATGCACGCCCTGCTCGCCCAGCCGGGCCACGCCGTGGCCAAGGAGCGGCTGTACGAGCTGG
TGTTCCCGGGGCAGCTGGACGTGCAGTACGAGGCCATCGAGGTGGTGGTGTACCGGCTGCGCAAGAAGCTGGCCGGCACC
GGGCTCACGCTCATGACGCTGCGCGGGCTGGGCTACCTGCTCAAGGCGGATGCATGA

Upstream 100 bases:

>100_bases
GCGGCAGCGCACCGGCGGCCGCGAGGGCTGCCAGGGACTTGAGGAAGGTATCGCGACGCATGGTTCTTGTCTCCTTGTGG
TATGGCGAACGGGGCCGATG

Downstream 100 bases:

>100_bases
GCGCCGCCCGGAGGGCGGCGCCGTGAGCGGCGCAGCGGGCCGAGCGCAGTCGCTGCGGCGGCGCCTGCTGCTGGGCATCC
TGGTGCCGGTGGCGCTGTTC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MRPLPVKRLSADSGKTPMGATGVPGAMVPRMQLLLVEDDPAMQATLQRSLARRGMEVTALGDGRAALAQWASRPPDAVVL
DLTLPGLDGLQVLQQARARGLRTPVLLLTARGTVGDRVLGLNAGADDYLPKPFDLDELEARLRALVRRLGDLSEARPPAP
STVSIGAIRYEKDSGAIYRDGEVMELTPRELALMHALLAQPGHAVAKERLYELVFPGQLDVQYEAIEVVVYRLRKKLAGT
GLTLMTLRGLGYLLKADA

Sequences:

>Translated_258_residues
MRPLPVKRLSADSGKTPMGATGVPGAMVPRMQLLLVEDDPAMQATLQRSLARRGMEVTALGDGRAALAQWASRPPDAVVL
DLTLPGLDGLQVLQQARARGLRTPVLLLTARGTVGDRVLGLNAGADDYLPKPFDLDELEARLRALVRRLGDLSEARPPAP
STVSIGAIRYEKDSGAIYRDGEVMELTPRELALMHALLAQPGHAVAKERLYELVFPGQLDVQYEAIEVVVYRLRKKLAGT
GLTLMTLRGLGYLLKADA
>Mature_258_residues
MRPLPVKRLSADSGKTPMGATGVPGAMVPRMQLLLVEDDPAMQATLQRSLARRGMEVTALGDGRAALAQWASRPPDAVVL
DLTLPGLDGLQVLQQARARGLRTPVLLLTARGTVGDRVLGLNAGADDYLPKPFDLDELEARLRALVRRLGDLSEARPPAP
STVSIGAIRYEKDSGAIYRDGEVMELTPRELALMHALLAQPGHAVAKERLYELVFPGQLDVQYEAIEVVVYRLRKKLAGT
GLTLMTLRGLGYLLKADA

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=37.5, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=35.6828193832599, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=34.2105263157895, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789809, Length=238, Percent_Identity=31.5126050420168, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=32.15859030837, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=30.6666666666667, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=32.4561403508772, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=32.7510917030568, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=30.1310043668122, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=35.9307359307359, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=32.4675324675325, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=32.5892857142857, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=39.8148148148148, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=29.7872340425532, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790299, Length=105, Percent_Identity=39.0476190476191, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790437, Length=139, Percent_Identity=32.3741007194245, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787487, Length=116, Percent_Identity=33.6206896551724, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27874; Mature: 27874

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLPVKRLSADSGKTPMGATGVPGAMVPRMQLLLVEDDPAMQATLQRSLARRGMEVTAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
GDGRAALAQWASRPPDAVVLDLTLPGLDGLQVLQQARARGLRTPVLLLTARGTVGDRVLG
CCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEE
LNAGADDYLPKPFDLDELEARLRALVRRLGDLSEARPPAPSTVSIGAIRYEKDSGAIYRD
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCEEEC
GEVMELTPRELALMHALLAQPGHAVAKERLYELVFPGQLDVQYEAIEVVVYRLRKKLAGT
CCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
GLTLMTLRGLGYLLKADA
CHHHHHHHHCCCEEECCC
>Mature Secondary Structure
MRPLPVKRLSADSGKTPMGATGVPGAMVPRMQLLLVEDDPAMQATLQRSLARRGMEVTAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
GDGRAALAQWASRPPDAVVLDLTLPGLDGLQVLQQARARGLRTPVLLLTARGTVGDRVLG
CCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEE
LNAGADDYLPKPFDLDELEARLRALVRRLGDLSEARPPAPSTVSIGAIRYEKDSGAIYRD
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCEEEC
GEVMELTPRELALMHALLAQPGHAVAKERLYELVFPGQLDVQYEAIEVVVYRLRKKLAGT
CCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
GLTLMTLRGLGYLLKADA
CHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]