Click here to switch to the map view.

The map label for this gene is nrdR

Identifier: 120611656

GI number: 120611656

Start: 3299832

End: 3300281

Strand: Direct

Name: nrdR

Synonym: Aave_2993

Alternate gene names: 120611656

Gene position: 3299832-3300281 (Clockwise)

Preceding gene: 120611655

Following gene: 120611657

Centisome position: 61.65

GC content: 63.56

Gene sequence:

>450_bases
ATGAAGTGCCCGTTCTGCAGCCACCCCGAGACGCAGGTCGTCGAAACGCGCGTGGCCGAGGATGGAGACTTCGTGCGGCG
GCGCCGGCAGTGCGGGGCCTGCGACAAGCGCTTCACGACCTATGAGCGCCCGGAAGTCAGCTTCCCCAACGTGGTGAAGA
AGGACGGCCGGCGCATCGAATACGACCGCAGCAAGCTCATCGGCTCGTTCAGCATCGCGCTGCGCAAGCGGCCGGTGAGC
ACGACGCAGATCGACAGCGCCATCGAGCGCATCGAGGAAAAGCTGCTCAACCTCGGGCAGCGCGAAGTGCTGTCCAGCCG
CATCGGCGAACTGGTGATGCGCGAGCTCAAGAAGCTAGACAAGGTCGCCTACATCCGATTCGCGAGCGTGTACCGGAACT
TCGAGGACATCGACGAATTCCGGGCGCTCGTGGACGAAGTGCGCAAATAG

Upstream 100 bases:

>100_bases
AGCCAACCTGGCCGCGGTGCGCGAGAAGGTGCACGCGCTCACGAGCCGCTTCCCGGTCTATCGCTGACCGCGGCGCAGCC
CCGAGCCCGCCGCCCCTGCA

Downstream 100 bases:

>100_bases
GCCGTCTGGCCCGGCGATGCGGACCGGCCGGGGCGCGTCGGCCGTGGTCCTACGCGCGGGGCGCCGCATGCCCTGCACAA
TCGACCGGCCCGGCAGCCCA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKCPFCSHPETQVVETRVAEDGDFVRRRRQCGACDKRFTTYERPEVSFPNVVKKDGRRIEYDRSKLIGSFSIALRKRPVS
TTQIDSAIERIEEKLLNLGQREVLSSRIGELVMRELKKLDKVAYIRFASVYRNFEDIDEFRALVDEVRK

Sequences:

>Translated_149_residues
MKCPFCSHPETQVVETRVAEDGDFVRRRRQCGACDKRFTTYERPEVSFPNVVKKDGRRIEYDRSKLIGSFSIALRKRPVS
TTQIDSAIERIEEKLLNLGQREVLSSRIGELVMRELKKLDKVAYIRFASVYRNFEDIDEFRALVDEVRK
>Mature_149_residues
MKCPFCSHPETQVVETRVAEDGDFVRRRRQCGACDKRFTTYERPEVSFPNVVKKDGRRIEYDRSKLIGSFSIALRKRPVS
TTQIDSAIERIEEKLLNLGQREVLSSRIGELVMRELKKLDKVAYIRFASVYRNFEDIDEFRALVDEVRK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=140, Percent_Identity=52.8571428571429, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_ACIAC (A1TRH2)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_971334.1
- STRING:   A1TRH2
- GeneID:   4667478
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_2993
- NMPDR:   fig|397945.5.peg.2547
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   A1TRH2
- ProtClustDB:   PRK00464
- BioCyc:   AAVE397945:AAVE_2993-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17477; Mature: 17477

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCSHPETQVVETRVAEDGDFVRRRRQCGACDKRFTTYERPEVSFPNVVKKDGRRIE
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHCCCCCH
YDRSKLIGSFSIALRKRPVSTTQIDSAIERIEEKLLNLGQREVLSSRIGELVMRELKKLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KVAYIRFASVYRNFEDIDEFRALVDEVRK
HHHHHHHHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKCPFCSHPETQVVETRVAEDGDFVRRRRQCGACDKRFTTYERPEVSFPNVVKKDGRRIE
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHCCCCCH
YDRSKLIGSFSIALRKRPVSTTQIDSAIERIEEKLLNLGQREVLSSRIGELVMRELKKLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KVAYIRFASVYRNFEDIDEFRALVDEVRK
HHHHHHHHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA