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The map label for this gene is slt [C]

Identifier: 120611654

GI number: 120611654

Start: 3297428

End: 3298315

Strand: Direct

Name: slt [C]

Synonym: Aave_2991

Alternate gene names: 120611654

Gene position: 3297428-3298315 (Clockwise)

Preceding gene: 120611649

Following gene: 120611655

Centisome position: 61.6

GC content: 69.26

Gene sequence:

>888_bases
ATGACAGCGTCAGGACGGGTGATCGGCGGAGTGCAGACCTTCGCATCCGATGTGATCGACGGTTTCCTCGAAATCACCCA
CAGCAGTTTCGCCCTGGTCGGGCTGACGGTCGCGTTCGGCGTGATCACCCTCACCGCCCGCCCGGACCTGCGGCAGGCCG
GAGAGGAAAAGCTCATGGGCTGGCTGCAGGCGCGCCAGGTGGCGATGGTCGGCGTGCCGATGGAGCCCGAGGCCAGCGAG
CGCGCCACGGCCACGAACCCGAAAGACCTGCCCAAGGAGCAGGCCGCCGTCGCGTTCTGGCTCAGCAAGAAGTACCGCGT
GGCGCCCGAACCCCTCGCCGCGCTGGTCTCCGAGGCCTACGAAATCGGCGGCCGCACCAAGCTCGATCCCACGCTCATCC
TGGCCATCATGGCCGTCGAATCGAGCTTCAACCCCTTCGCGCAAAGCCCCGTGGGCGCACAGGGCCTGATGCAGGTCATG
ACGCGGGTGCATACCGACAAGTACGAGAACTTCGGCGGCCATTTCGCCGCCTTCGACCCGGTGAGCAACCTGCGCGTCGG
CGTCCGTGTGCTGCAGGAATGCATCGCCCGCGCAGGTTCCCTCGAAGGCGGGCTGCGCTACTACGTGGGCGCGGCCAACC
TGGCCGACGACGGCGGCTACGCGATCAAGGTCATGGCCGAGCACATGCGCCTGCGCCAGGTGGCCAACGGTCGCAACGTG
CCCATCTTCACGCCTCCGGCACCGGCCGCTCCCGCCGCGCCCCCGATGCTGTCCACCCAGGCCCCGGCGCAGACCACGCT
GCCGGCCAAGGGCGCGGGCACCGCCGATGCGTCGCCCGCCACCTCCACGGGCGACGACAAGGTCGCCCTGCTCTCCTCCG
GGCTCTGA

Upstream 100 bases:

>100_bases
GGGAACTGGATGGCGTACCAATCCAGGCGAGATGCCTGGCACGGGAGACCCCCACTACGGGGGTCGCCCGCAACAGGCCT
CGACTCAGAAAGGAAGAGCT

Downstream 100 bases:

>100_bases
CGTTCCTGGCGACGCCATCCCGCCCTGCCGTCCGCTACACTCGAGGGGTACGCGACTGGCGATAGGCGCGGTGCATCCGC
GAAGGCGGACGCCGCCGCTG

Product: lytic transglycosylase catalytic subunit

Products: 1,6-Anhydrobond [C]

Alternate protein names: Transglycosylase; Transglycosylase SLT Family Protein; Transglycosylase SLT Family; Lytic Transglycosylase; Transglycosylase SLT Domain-Containing Lipoprotein; Transmembrane Protein; Transglycosylase Protein; Transglycosylase SLT Domain-Containing; Transmembrane Transglycosylase SLT Family Protein

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTASGRVIGGVQTFASDVIDGFLEITHSSFALVGLTVAFGVITLTARPDLRQAGEEKLMGWLQARQVAMVGVPMEPEASE
RATATNPKDLPKEQAAVAFWLSKKYRVAPEPLAALVSEAYEIGGRTKLDPTLILAIMAVESSFNPFAQSPVGAQGLMQVM
TRVHTDKYENFGGHFAAFDPVSNLRVGVRVLQECIARAGSLEGGLRYYVGAANLADDGGYAIKVMAEHMRLRQVANGRNV
PIFTPPAPAAPAAPPMLSTQAPAQTTLPAKGAGTADASPATSTGDDKVALLSSGL

Sequences:

>Translated_295_residues
MTASGRVIGGVQTFASDVIDGFLEITHSSFALVGLTVAFGVITLTARPDLRQAGEEKLMGWLQARQVAMVGVPMEPEASE
RATATNPKDLPKEQAAVAFWLSKKYRVAPEPLAALVSEAYEIGGRTKLDPTLILAIMAVESSFNPFAQSPVGAQGLMQVM
TRVHTDKYENFGGHFAAFDPVSNLRVGVRVLQECIARAGSLEGGLRYYVGAANLADDGGYAIKVMAEHMRLRQVANGRNV
PIFTPPAPAAPAAPPMLSTQAPAQTTLPAKGAGTADASPATSTGDDKVALLSSGL
>Mature_294_residues
TASGRVIGGVQTFASDVIDGFLEITHSSFALVGLTVAFGVITLTARPDLRQAGEEKLMGWLQARQVAMVGVPMEPEASER
ATATNPKDLPKEQAAVAFWLSKKYRVAPEPLAALVSEAYEIGGRTKLDPTLILAIMAVESSFNPFAQSPVGAQGLMQVMT
RVHTDKYENFGGHFAAFDPVSNLRVGVRVLQECIARAGSLEGGLRYYVGAANLADDGGYAIKVMAEHMRLRQVANGRNVP
IFTPPAPAAPAAPPMLSTQAPAQTTLPAKGAGTADASPATSTGDDKVALLSSGL

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 30963; Mature: 30832

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASGRVIGGVQTFASDVIDGFLEITHSSFALVGLTVAFGVITLTARPDLRQAGEEKLMG
CCCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
WLQARQVAMVGVPMEPEASERATATNPKDLPKEQAAVAFWLSKKYRVAPEPLAALVSEAY
HHHHHHHHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
EIGGRTKLDPTLILAIMAVESSFNPFAQSPVGAQGLMQVMTRVHTDKYENFGGHFAAFDP
HCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
VSNLRVGVRVLQECIARAGSLEGGLRYYVGAANLADDGGYAIKVMAEHMRLRQVANGRNV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHCCCCC
PIFTPPAPAAPAAPPMLSTQAPAQTTLPAKGAGTADASPATSTGDDKVALLSSGL
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHCCCCC
>Mature Secondary Structure 
TASGRVIGGVQTFASDVIDGFLEITHSSFALVGLTVAFGVITLTARPDLRQAGEEKLMG
CCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
WLQARQVAMVGVPMEPEASERATATNPKDLPKEQAAVAFWLSKKYRVAPEPLAALVSEAY
HHHHHHHHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
EIGGRTKLDPTLILAIMAVESSFNPFAQSPVGAQGLMQVMTRVHTDKYENFGGHFAAFDP
HCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
VSNLRVGVRVLQECIARAGSLEGGLRYYVGAANLADDGGYAIKVMAEHMRLRQVANGRNV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHCCCCC
PIFTPPAPAAPAAPPMLSTQAPAQTTLPAKGAGTADASPATSTGDDKVALLSSGL
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA