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The map label for this gene is mtaD [H]

Identifier: 120611623

GI number: 120611623

Start: 3249255

End: 3250676

Strand: Reverse

Name: mtaD [H]

Synonym: Aave_2960

Alternate gene names: 120611623

Gene position: 3250676-3249255 (Counterclockwise)

Preceding gene: 120611624

Following gene: 120611622

Centisome position: 60.73

GC content: 74.12

Gene sequence:

>1422_bases
ATGACCGGCCAGACTTTCCACTCCGGCGGCGGCGCGCTCTTCGCCGCACAGGCGCTGCTGCCCGGCGGCTGGGCAAGGGA
CGTGCTGCTGCGCTGGAACGAACACGGGCGCATCACCCACGTACAGCCCGACAGTGCCCCGCCGCCCGCCGTGGCGCGCG
CACCCGGTCCGCTGCTGCCGGGCCTGCCCAACCTGCATTCCCACGCGTTCCAGCGCGCCTTCGCCGGCCTGACCGAATTC
CGCGCGGCCAGCGACGACTCGTTCTGGAGCTGGCGCGACCTCATGTACCGCTTCGCCGCGCGCATGTCGCCCGAGGCGCT
GGAGGCGATCGCCACCTGGCTCTATGTGGAGATGCTGGAGGCCGGCTACACGGCGGTGTGCGAGTTCCATTACCTGCACC
ATGCCGGGGACGGCCGCCCCTATGCCGACGACGCCGAGATGTCGCTCGCGCTGCTGCGCGCAGCACGGCGTGCCGGCATC
GGCATCACCCTGCTGCCGGTGCTCTACCAGGCCAGCGGCTTCGGCGGCCAGCCGCCCCGCGAGGGCCAGCGGCGCTTCCT
GCACCGTACCGACGGCATGCTCGCGCTGCTCGAACGCCTCGCGCCCGTGGTGCGCGCGCAGGGCGGCGTGCTGGGCCTCG
CACCGCATTCCCTGCGCGCCGTGCCGCCCGACAGCCTGAACGCGGCACTGCAGGGCCTGGACGCCATCGTTCCCGCCGCG
CCGGTGCACATCCACATCGCCGAGCAGACGCAGGAGGTGCATGACTGCATCGCCTGGAGCGGCCAGCGGCCCGTGGAGTG
GCTGCTGGACCATGCGCCCGTCGATGCGCGCTGGTGCCTCGTCCACGCCACGCACCTGAGCGATGCGGAGGCCGCACGCG
CGGCCCGGTCCGGTGCCGTGGCGGGGCTGTGCCCGACGACCGAGGCCAACCTGGGCGACGGCATCTTCGACCTGCCGCGC
TGGCGGGCGGCCGGCGGGGCCTGGGGCCTGGGCTCCGACAGCCATGCCTGCGTGAACGCGGCCGAAGAGCTGATGCTGCT
CGAATACGGCCAGCGGCTGGCCCTGCGCCGCCGCAACGTGCTGGGCACCGAAGCGCAACCGCAGGTCGCCACCGCCATGC
TGCTGCAGGCCGTGCAGGGCGGCGCGCAGGCCGCCGGCCGTCTGCCGTCGCCCGGCGCGCGGGCGGGCCTCGCGCCGGGC
GCTCCGGCCGATTTCGTCGTGCTGGATCCGGAGCACATCGCGTTGCGCGGCCTGCCGGCCGAGAGCCAGCTCGCCGCCCA
TGTCTTCGCCAGCCACCGCACATCGGCGCTCGATGCCGTCTGGACGGCCGGCGTGCAGCGCGTCGCCGGGGGCCGCCATG
CCCTGCACGAAGAGAGCGCGGCCGCCTTCGCCGGGGTACGCTCCGGGCTGCTGCAATACTGA

Upstream 100 bases:

>100_bases
ACTTCGTGCTCTGGCCCTTCGCCGAAGCGGCCGAGCTGGCCTACTGGTTCGGCCACCAGCCGCCGCAGGCGATCGTCCGG
CAGGGCAGGGTGGTGCAGCG

Downstream 100 bases:

>100_bases
AACTGTCTTGTCACGAGAACGCCCATGAACGACGCACCGGCCACGCCGCTCTTCCATTTCCATGCAGGCACCGCGCCGTT
GCTGGTGTCCATGCCGCACG

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MTGQTFHSGGGALFAAQALLPGGWARDVLLRWNEHGRITHVQPDSAPPPAVARAPGPLLPGLPNLHSHAFQRAFAGLTEF
RAASDDSFWSWRDLMYRFAARMSPEALEAIATWLYVEMLEAGYTAVCEFHYLHHAGDGRPYADDAEMSLALLRAARRAGI
GITLLPVLYQASGFGGQPPREGQRRFLHRTDGMLALLERLAPVVRAQGGVLGLAPHSLRAVPPDSLNAALQGLDAIVPAA
PVHIHIAEQTQEVHDCIAWSGQRPVEWLLDHAPVDARWCLVHATHLSDAEAARAARSGAVAGLCPTTEANLGDGIFDLPR
WRAAGGAWGLGSDSHACVNAAEELMLLEYGQRLALRRRNVLGTEAQPQVATAMLLQAVQGGAQAAGRLPSPGARAGLAPG
APADFVVLDPEHIALRGLPAESQLAAHVFASHRTSALDAVWTAGVQRVAGGRHALHEESAAAFAGVRSGLLQY

Sequences:

>Translated_473_residues
MTGQTFHSGGGALFAAQALLPGGWARDVLLRWNEHGRITHVQPDSAPPPAVARAPGPLLPGLPNLHSHAFQRAFAGLTEF
RAASDDSFWSWRDLMYRFAARMSPEALEAIATWLYVEMLEAGYTAVCEFHYLHHAGDGRPYADDAEMSLALLRAARRAGI
GITLLPVLYQASGFGGQPPREGQRRFLHRTDGMLALLERLAPVVRAQGGVLGLAPHSLRAVPPDSLNAALQGLDAIVPAA
PVHIHIAEQTQEVHDCIAWSGQRPVEWLLDHAPVDARWCLVHATHLSDAEAARAARSGAVAGLCPTTEANLGDGIFDLPR
WRAAGGAWGLGSDSHACVNAAEELMLLEYGQRLALRRRNVLGTEAQPQVATAMLLQAVQGGAQAAGRLPSPGARAGLAPG
APADFVVLDPEHIALRGLPAESQLAAHVFASHRTSALDAVWTAGVQRVAGGRHALHEESAAAFAGVRSGLLQY
>Mature_472_residues
TGQTFHSGGGALFAAQALLPGGWARDVLLRWNEHGRITHVQPDSAPPPAVARAPGPLLPGLPNLHSHAFQRAFAGLTEFR
AASDDSFWSWRDLMYRFAARMSPEALEAIATWLYVEMLEAGYTAVCEFHYLHHAGDGRPYADDAEMSLALLRAARRAGIG
ITLLPVLYQASGFGGQPPREGQRRFLHRTDGMLALLERLAPVVRAQGGVLGLAPHSLRAVPPDSLNAALQGLDAIVPAAP
VHIHIAEQTQEVHDCIAWSGQRPVEWLLDHAPVDARWCLVHATHLSDAEAARAARSGAVAGLCPTTEANLGDGIFDLPRW
RAAGGAWGLGSDSHACVNAAEELMLLEYGQRLALRRRNVLGTEAQPQVATAMLLQAVQGGAQAAGRLPSPGARAGLAPGA
PADFVVLDPEHIALRGLPAESQLAAHVFASHRTSALDAVWTAGVQRVAGGRHALHEESAAAFAGVRSGLLQY

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540282, Length=440, Percent_Identity=28.1818181818182, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 50294; Mature: 50162

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGQTFHSGGGALFAAQALLPGGWARDVLLRWNEHGRITHVQPDSAPPPAVARAPGPLLP
CCCCCEECCCCCEEHHHHHCCCCHHHHHHHEECCCCCEEEECCCCCCCCCCCCCCCCCCC
GLPNLHSHAFQRAFAGLTEFRAASDDSFWSWRDLMYRFAARMSPEALEAIATWLYVEMLE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AGYTAVCEFHYLHHAGDGRPYADDAEMSLALLRAARRAGIGITLLPVLYQASGFGGQPPR
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCCCCH
EGQRRFLHRTDGMLALLERLAPVVRAQGGVLGLAPHSLRAVPPDSLNAALQGLDAIVPAA
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC
PVHIHIAEQTQEVHDCIAWSGQRPVEWLLDHAPVDARWCLVHATHLSDAEAARAARSGAV
CEEEEEHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCC
AGLCPTTEANLGDGIFDLPRWRAAGGAWGLGSDSHACVNAAEELMLLEYGQRLALRRRNV
EECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
LGTEAQPQVATAMLLQAVQGGAQAAGRLPSPGARAGLAPGAPADFVVLDPEHIALRGLPA
CCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCC
ESQLAAHVFASHRTSALDAVWTAGVQRVAGGRHALHEESAAAFAGVRSGLLQY
HHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGQTFHSGGGALFAAQALLPGGWARDVLLRWNEHGRITHVQPDSAPPPAVARAPGPLLP
CCCCEECCCCCEEHHHHHCCCCHHHHHHHEECCCCCEEEECCCCCCCCCCCCCCCCCCC
GLPNLHSHAFQRAFAGLTEFRAASDDSFWSWRDLMYRFAARMSPEALEAIATWLYVEMLE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AGYTAVCEFHYLHHAGDGRPYADDAEMSLALLRAARRAGIGITLLPVLYQASGFGGQPPR
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCCCCH
EGQRRFLHRTDGMLALLERLAPVVRAQGGVLGLAPHSLRAVPPDSLNAALQGLDAIVPAA
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC
PVHIHIAEQTQEVHDCIAWSGQRPVEWLLDHAPVDARWCLVHATHLSDAEAARAARSGAV
CEEEEEHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCC
AGLCPTTEANLGDGIFDLPRWRAAGGAWGLGSDSHACVNAAEELMLLEYGQRLALRRRNV
EECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
LGTEAQPQVATAMLLQAVQGGAQAAGRLPSPGARAGLAPGAPADFVVLDPEHIALRGLPA
CCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCC
ESQLAAHVFASHRTSALDAVWTAGVQRVAGGRHALHEESAAAFAGVRSGLLQY
HHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA