Click here to switch to the map view.

The map label for this gene is pgm [H]

Identifier: 120611486

GI number: 120611486

Start: 3096613

End: 3098073

Strand: Reverse

Name: pgm [H]

Synonym: Aave_2822

Alternate gene names: 120611486

Gene position: 3098073-3096613 (Counterclockwise)

Preceding gene: 120611491

Following gene: 120611485

Centisome position: 57.88

GC content: 69.82

Gene sequence:

>1461_bases
ATGCACGGCCGCGCCGGCGCCATGAAGGGCGCCGTGGCCGCAGTGCGGGCCTGCCAGCAAAGGAACCTTCCCGTGCAGCT
TCATTCCGCCATTTTCAAGGCCTACGATATCCGCGGCGTCGTGCCGACCACCCTGACCGAAGACGTCGCGCGCGCCCTGG
GCCGCGCATTTGGCACGGCGGCCCGCCGCGAAGGCCAGACCACCGTGGCGGTGGGGCGGGACGGGCGGCTGTCCGGCCCG
GCGCTGTCCCGCGCGCTGATCGAAGGCCTGGTGGACGCAGGCATCGAGGTGATCGACGTCGGCGCCGTGACCACGCCGAT
GCTGTACTTCGCGGCCCACACCCTGTGCCAGAGCGGCATCCAGGTGACGGGCAGCCACAACCCCAAGGATTACAACGGCT
TCAAGATGGTGCTGGCCGGCCGTGCCATCTACGGCGAGGAGATCCAGGGCCTGCGCCGCACGATGGAAGAGGAGAGCTGG
GAATTACAGCCCGGCGGCTCGGTGCGGCAGGCCGACGTGCTGCCCGCCTACGTGCAGCGCATCACGTCCGACGTGAAGCT
CGAGCGCCCCATCAAGATCGTGGTGGACAGCGGCAACGGCATCGCGGGCGCGTCTGCGCCGGGTATCTTCCGGGCGCTGG
GCTGCGAGGTGATCGAGCTGTTCTCCCAGGTGGACGGCAATTTCCCCAATCACCACCCGGACCCCAGCAAGCCCGAGAAC
CTGCGCGACCTGATCCGCGCGCTGCAGGAGAGCGACGCCGAGCTGGGCCTGGCCTTCGACGGCGACGGCGACCGGCTGGG
CATCGTCACCAAGGACGGGCAGAACATCTTCCCCGACCGCCAGATGATGCTGTTCGCGCGCGACGTGCTCTCGCGCGTGC
CGGGCGCGCCCATCCTGTTCGACGTGAAGTGCACGCAGCGCCTGGCCCCGGCGATCGAGGCCGTGGGTGGCCAGGCCGTG
ATGTACAAGACCGGCCATTCGCTCATCAAGGCGCGCATGAAGGAACTCGACTCGCCGCTGGGTGGCGAGATGAGCGGCCA
CATCTTCTTCAAGGAGCGCTGGTTCGGCTTCGACGACGGCACCTACGCCGGCTGCCGGCTGCTCGAGATCCTGAGCCGCC
ATGCCGACCCGAGCGCGGTGCTCAACGACCTGCCCACCAGCCATTCGACGCCCGAGCTGAACGTGGCCTGCGAGGAGGGC
GAGCCCCACCGCCTGACGGCCGAGCTGCAGGCGCTGGCGCAGAGCGCGTTCCCGGAGCCGGCGCGCATCAGCACCATCGA
CGGCCTGCGGGTGGACTGGCCGGACGGCTTCGGCCTGATCCGGGCGAGCAACACCACGCCGGTGCTGGTGCTGCGTTTCG
AGGGGCATACGCCCGAGGCGCTGCACCGCATCGAAGGCGCCATGCTGGAGCTGCTGCAGCGCGTGAAGCCCGGCGCAGCT
CCGGGCGCGGCCGCGCATTGA

Upstream 100 bases:

>100_bases
GCCCGTCCGCCGGGAGTGCGCACGACGCCTACAATCCCCGCGAATCCGCAGATGGCGTGCCTCCGTTACCTGGAGGGCGC
CGCATTCGCTCCACCGGCCC

Downstream 100 bases:

>100_bases
GGACGAGTGCCATGCGCGTCGCGGCGGCCCAGGCCTCCTCCCTGCCCGGCGGTCCGGAAGCGAATGTCGGCAACCACCTG
CGCTTCGCCGAGGCCGCGGC

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MHGRAGAMKGAVAAVRACQQRNLPVQLHSAIFKAYDIRGVVPTTLTEDVARALGRAFGTAARREGQTTVAVGRDGRLSGP
ALSRALIEGLVDAGIEVIDVGAVTTPMLYFAAHTLCQSGIQVTGSHNPKDYNGFKMVLAGRAIYGEEIQGLRRTMEEESW
ELQPGGSVRQADVLPAYVQRITSDVKLERPIKIVVDSGNGIAGASAPGIFRALGCEVIELFSQVDGNFPNHHPDPSKPEN
LRDLIRALQESDAELGLAFDGDGDRLGIVTKDGQNIFPDRQMMLFARDVLSRVPGAPILFDVKCTQRLAPAIEAVGGQAV
MYKTGHSLIKARMKELDSPLGGEMSGHIFFKERWFGFDDGTYAGCRLLEILSRHADPSAVLNDLPTSHSTPELNVACEEG
EPHRLTAELQALAQSAFPEPARISTIDGLRVDWPDGFGLIRASNTTPVLVLRFEGHTPEALHRIEGAMLELLQRVKPGAA
PGAAAH

Sequences:

>Translated_486_residues
MHGRAGAMKGAVAAVRACQQRNLPVQLHSAIFKAYDIRGVVPTTLTEDVARALGRAFGTAARREGQTTVAVGRDGRLSGP
ALSRALIEGLVDAGIEVIDVGAVTTPMLYFAAHTLCQSGIQVTGSHNPKDYNGFKMVLAGRAIYGEEIQGLRRTMEEESW
ELQPGGSVRQADVLPAYVQRITSDVKLERPIKIVVDSGNGIAGASAPGIFRALGCEVIELFSQVDGNFPNHHPDPSKPEN
LRDLIRALQESDAELGLAFDGDGDRLGIVTKDGQNIFPDRQMMLFARDVLSRVPGAPILFDVKCTQRLAPAIEAVGGQAV
MYKTGHSLIKARMKELDSPLGGEMSGHIFFKERWFGFDDGTYAGCRLLEILSRHADPSAVLNDLPTSHSTPELNVACEEG
EPHRLTAELQALAQSAFPEPARISTIDGLRVDWPDGFGLIRASNTTPVLVLRFEGHTPEALHRIEGAMLELLQRVKPGAA
PGAAAH
>Mature_486_residues
MHGRAGAMKGAVAAVRACQQRNLPVQLHSAIFKAYDIRGVVPTTLTEDVARALGRAFGTAARREGQTTVAVGRDGRLSGP
ALSRALIEGLVDAGIEVIDVGAVTTPMLYFAAHTLCQSGIQVTGSHNPKDYNGFKMVLAGRAIYGEEIQGLRRTMEEESW
ELQPGGSVRQADVLPAYVQRITSDVKLERPIKIVVDSGNGIAGASAPGIFRALGCEVIELFSQVDGNFPNHHPDPSKPEN
LRDLIRALQESDAELGLAFDGDGDRLGIVTKDGQNIFPDRQMMLFARDVLSRVPGAPILFDVKCTQRLAPAIEAVGGQAV
MYKTGHSLIKARMKELDSPLGGEMSGHIFFKERWFGFDDGTYAGCRLLEILSRHADPSAVLNDLPTSHSTPELNVACEEG
EPHRLTAELQALAQSAFPEPARISTIDGLRVDWPDGFGLIRASNTTPVLVLRFEGHTPEALHRIEGAMLELLQRVKPGAA
PGAAAH

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=439, Percent_Identity=35.3075170842825, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1789566, Length=461, Percent_Identity=28.1995661605206, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 52307; Mature: 52307

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGRAGAMKGAVAAVRACQQRNLPVQLHSAIFKAYDIRGVVPTTLTEDVARALGRAFGTA
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ARREGQTTVAVGRDGRLSGPALSRALIEGLVDAGIEVIDVGAVTTPMLYFAAHTLCQSGI
HHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCC
QVTGSHNPKDYNGFKMVLAGRAIYGEEIQGLRRTMEEESWELQPGGSVRQADVLPAYVQR
EEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ITSDVKLERPIKIVVDSGNGIAGASAPGIFRALGCEVIELFSQVDGNFPNHHPDPSKPEN
HHHCCEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
LRDLIRALQESDAELGLAFDGDGDRLGIVTKDGQNIFPDRQMMLFARDVLSRVPGAPILF
HHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
DVKCTQRLAPAIEAVGGQAVMYKTGHSLIKARMKELDSPLGGEMSGHIFFKERWFGFDDG
ECHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCC
TYAGCRLLEILSRHADPSAVLNDLPTSHSTPELNVACEEGEPHRLTAELQALAQSAFPEP
CHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
ARISTIDGLRVDWPDGFGLIRASNTTPVLVLRFEGHTPEALHRIEGAMLELLQRVKPGAA
CCEEEECCCEEECCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
PGAAAH
CCCCCC
>Mature Secondary Structure
MHGRAGAMKGAVAAVRACQQRNLPVQLHSAIFKAYDIRGVVPTTLTEDVARALGRAFGTA
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ARREGQTTVAVGRDGRLSGPALSRALIEGLVDAGIEVIDVGAVTTPMLYFAAHTLCQSGI
HHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCC
QVTGSHNPKDYNGFKMVLAGRAIYGEEIQGLRRTMEEESWELQPGGSVRQADVLPAYVQR
EEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ITSDVKLERPIKIVVDSGNGIAGASAPGIFRALGCEVIELFSQVDGNFPNHHPDPSKPEN
HHHCCEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
LRDLIRALQESDAELGLAFDGDGDRLGIVTKDGQNIFPDRQMMLFARDVLSRVPGAPILF
HHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
DVKCTQRLAPAIEAVGGQAVMYKTGHSLIKARMKELDSPLGGEMSGHIFFKERWFGFDDG
ECHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCC
TYAGCRLLEILSRHADPSAVLNDLPTSHSTPELNVACEEGEPHRLTAELQALAQSAFPEP
CHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
ARISTIDGLRVDWPDGFGLIRASNTTPVLVLRFEGHTPEALHRIEGAMLELLQRVKPGAA
CCEEEECCCEEECCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
PGAAAH
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]