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The map label for this gene is ygjG [C]

Identifier: 120610855

GI number: 120610855

Start: 2398054

End: 2399457

Strand: Reverse

Name: ygjG [C]

Synonym: Aave_2181

Alternate gene names: 120610855

Gene position: 2399457-2398054 (Counterclockwise)

Preceding gene: 120610856

Following gene: 120610854

Centisome position: 44.83

GC content: 69.44

Gene sequence:

>1404_bases
ATGACCCACTCCGAAGCCCTTCCCCAGATCGCAGCGCTGGACGCACTGGACCGTGCCCATCTCATCCATCCGGTCGCTCC
GTGGCGCACCCACGAGGAACGCGGCCCGAACATCCTCACCGGGGCGAAGGGCATCTGGCTCACCGACGGCAAGGGGCACC
AGCTGCTCGACGCTTTCGCGGGCCTGTGGTGCGTGAACGTGGGCTACGGACAGGAGAGCGTGGTGCAGGCCGCCGCCGGG
CAGATGCGCACGCTGCCCTACGCCACCGGCTACTTCCACTTCAGCAGCGAACCCGCCATCCGCCTGGCCGACAAGCTGGT
GCAGATCACGCCCGCATCGCTGCAGCACGTGTACCTCACGCTGGGCGGGTCCGAGTCGGTCGATGCGGCCGTGCGGTTCA
TCGTGCAGTACAGCAACGCCATCGGCAAGCCGGGCAAGAAGCACTTCATCGCGCTGGAGCGCGGCTACCACGGCTCCTCG
TCCACAGGCGCGGGCCTGACGGCGCTGCCCGTCTTCCACCGCGGGTTCGACCTGCCCCTGCCCACGCAGCACTACATTCC
CTCGCCCAACCCCTACCGCGCCGCCGACCCGGCCGACGGGCAAGCCATCATCGACGCGTCCGTGGCGGCACTGCGGGCCA
AGGTGGCCGAGCTGGGCGCCGAGAACGTGGCGGCTTTCTTCTGCGAGCCCATCCAGGGCTCGGGCGGGGTCATCGTGCCG
CCCAGGGGCTGGCTCAAGGCCATGTGCGAGGCCGCGCATTCGCTGGACATCCTGTTCGTGGTGGACGAGGTCATCACCGG
CTTCGGCCGCACGGGCCCCATGTTCGCCTGCCAGGCCGAAGGCGTCGAGCCCGACCTGATGACCGTCGCCAAGGGCCTGA
CCTCGGGCTACGTGCCCATGGGCGCCACGCTCATGAGCCACCGCATCTACTCCGCCATCGCCGACGGCGCCCCCAGGGGT
GCCCCCATCGGCCACGGCGCCACCTACTCGGCCCATCCCGTGAGCGCGGCGGTGGCCCTGGAAGTCCTGCGCCTGTACGA
CGAAGGCGGAATACTGGCCAACGGCCAGCGTGTGGCAGCAGCGTTCGCGCAGGGCCTCGACGATCTTCTGGCCCACCCCC
TGGTCGGCGACTCGCGCCACCGCGGCCTGCTGGGAGCGCTGGAACTGGTCAGCAGCAAGACCACCAAGGCGGGCTTCGAC
GCGGCACTGGACCTGCCGGCGCGCATGGCGGCCACCAGCTACCGCAACGGCATCGTGTTCCGAGCGTTCGGCGACAACAT
CCTGGGCTTCGCCCCGGCCCTGACCTTCACGGAATCGGACTTCGGCCTCATGTTCGAGCGCGTGAAGAAGACCCTGGACG
ACGTGCTGGCCGTACCCGAAGTGCGCGCGGCCCTGAAGGATTGA

Upstream 100 bases:

>100_bases
AAACCAGCACCACGCGATCGGGCAATCGTCCTAACCTTGGAGACATAACGGCAGGTACCGCAGCGCCTGCACCTCTTCCC
CGCCACCTACGGACCACCCC

Downstream 100 bases:

>100_bases
TCCAGGGGCCGAACGGGTATAAATCCTGCTGCGCCCCTGCGGATCGCCATGTTGAATAGGCCATCCTTTCCCCTCTCTTT
ACGCGCCTGGAGCCCGCGAT

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTHSEALPQIAALDALDRAHLIHPVAPWRTHEERGPNILTGAKGIWLTDGKGHQLLDAFAGLWCVNVGYGQESVVQAAAG
QMRTLPYATGYFHFSSEPAIRLADKLVQITPASLQHVYLTLGGSESVDAAVRFIVQYSNAIGKPGKKHFIALERGYHGSS
STGAGLTALPVFHRGFDLPLPTQHYIPSPNPYRAADPADGQAIIDASVAALRAKVAELGAENVAAFFCEPIQGSGGVIVP
PRGWLKAMCEAAHSLDILFVVDEVITGFGRTGPMFACQAEGVEPDLMTVAKGLTSGYVPMGATLMSHRIYSAIADGAPRG
APIGHGATYSAHPVSAAVALEVLRLYDEGGILANGQRVAAAFAQGLDDLLAHPLVGDSRHRGLLGALELVSSKTTKAGFD
AALDLPARMAATSYRNGIVFRAFGDNILGFAPALTFTESDFGLMFERVKKTLDDVLAVPEVRAALKD

Sequences:

>Translated_467_residues
MTHSEALPQIAALDALDRAHLIHPVAPWRTHEERGPNILTGAKGIWLTDGKGHQLLDAFAGLWCVNVGYGQESVVQAAAG
QMRTLPYATGYFHFSSEPAIRLADKLVQITPASLQHVYLTLGGSESVDAAVRFIVQYSNAIGKPGKKHFIALERGYHGSS
STGAGLTALPVFHRGFDLPLPTQHYIPSPNPYRAADPADGQAIIDASVAALRAKVAELGAENVAAFFCEPIQGSGGVIVP
PRGWLKAMCEAAHSLDILFVVDEVITGFGRTGPMFACQAEGVEPDLMTVAKGLTSGYVPMGATLMSHRIYSAIADGAPRG
APIGHGATYSAHPVSAAVALEVLRLYDEGGILANGQRVAAAFAQGLDDLLAHPLVGDSRHRGLLGALELVSSKTTKAGFD
AALDLPARMAATSYRNGIVFRAFGDNILGFAPALTFTESDFGLMFERVKKTLDDVLAVPEVRAALKD
>Mature_466_residues
THSEALPQIAALDALDRAHLIHPVAPWRTHEERGPNILTGAKGIWLTDGKGHQLLDAFAGLWCVNVGYGQESVVQAAAGQ
MRTLPYATGYFHFSSEPAIRLADKLVQITPASLQHVYLTLGGSESVDAAVRFIVQYSNAIGKPGKKHFIALERGYHGSSS
TGAGLTALPVFHRGFDLPLPTQHYIPSPNPYRAADPADGQAIIDASVAALRAKVAELGAENVAAFFCEPIQGSGGVIVPP
RGWLKAMCEAAHSLDILFVVDEVITGFGRTGPMFACQAEGVEPDLMTVAKGLTSGYVPMGATLMSHRIYSAIADGAPRGA
PIGHGATYSAHPVSAAVALEVLRLYDEGGILANGQRVAAAFAQGLDDLLAHPLVGDSRHRGLLGALELVSSKTTKAGFDA
ALDLPARMAATSYRNGIVFRAFGDNILGFAPALTFTESDFGLMFERVKKTLDDVLAVPEVRAALKD

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=443, Percent_Identity=27.9909706546275, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI226442705, Length=444, Percent_Identity=28.3783783783784, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI226442709, Length=412, Percent_Identity=28.1553398058252, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI13994255, Length=404, Percent_Identity=28.7128712871287, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI24119277, Length=430, Percent_Identity=26.7441860465116, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4557809, Length=438, Percent_Identity=26.7123287671233, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI284507298, Length=232, Percent_Identity=31.4655172413793, Blast_Score=108, Evalue=8e-24,
Organism=Escherichia coli, GI145693181, Length=412, Percent_Identity=29.6116504854369, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786991, Length=431, Percent_Identity=27.6102088167053, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1789016, Length=439, Percent_Identity=26.6514806378132, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788044, Length=418, Percent_Identity=27.2727272727273, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789759, Length=443, Percent_Identity=27.0880361173815, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1787560, Length=419, Percent_Identity=26.9689737470167, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71992977, Length=441, Percent_Identity=27.2108843537415, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI32564660, Length=446, Percent_Identity=26.6816143497758, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=425, Percent_Identity=23.2941176470588, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144274, Length=244, Percent_Identity=28.2786885245902, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17541228, Length=448, Percent_Identity=23.4375, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324386, Length=422, Percent_Identity=27.7251184834123, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323470, Length=445, Percent_Identity=25.1685393258427, Blast_Score=113, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6324432, Length=414, Percent_Identity=22.463768115942, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6321456, Length=296, Percent_Identity=22.2972972972973, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI161085790, Length=449, Percent_Identity=28.7305122494432, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28574759, Length=392, Percent_Identity=29.8469387755102, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21356575, Length=414, Percent_Identity=25.1207729468599, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21357415, Length=436, Percent_Identity=25.2293577981651, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 49363; Mature: 49232

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSEALPQIAALDALDRAHLIHPVAPWRTHEERGPNILTGAKGIWLTDGKGHQLLDAFA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCEEECCCEEEEECCCCHHHHHHHH
GLWCVNVGYGQESVVQAAAGQMRTLPYATGYFHFSSEPAIRLADKLVQITPASLQHVYLT
HHEEEECCCCHHHHHHHHHCCCEECCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEE
LGGSESVDAAVRFIVQYSNAIGKPGKKHFIALERGYHGSSSTGAGLTALPVFHRGFDLPL
ECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHCCCCCCC
PTQHYIPSPNPYRAADPADGQAIIDASVAALRAKVAELGAENVAAFFCEPIQGSGGVIVP
CCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCHHHEEEHEECCCCCCCCEEEC
PRGWLKAMCEAAHSLDILFVVDEVITGFGRTGPMFACQAEGVEPDLMTVAKGLTSGYVPM
CHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCH
GATLMSHRIYSAIADGAPRGAPIGHGATYSAHPVSAAVALEVLRLYDEGGILANGQRVAA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHH
AFAQGLDDLLAHPLVGDSRHRGLLGALELVSSKTTKAGFDAALDLPARMAATSYRNGIVF
HHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHCCCEEE
RAFGDNILGFAPALTFTESDFGLMFERVKKTLDDVLAVPEVRAALKD
EECCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure 
THSEALPQIAALDALDRAHLIHPVAPWRTHEERGPNILTGAKGIWLTDGKGHQLLDAFA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCEEECCCEEEEECCCCHHHHHHHH
GLWCVNVGYGQESVVQAAAGQMRTLPYATGYFHFSSEPAIRLADKLVQITPASLQHVYLT
HHEEEECCCCHHHHHHHHHCCCEECCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEE
LGGSESVDAAVRFIVQYSNAIGKPGKKHFIALERGYHGSSSTGAGLTALPVFHRGFDLPL
ECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHCCCCCCC
PTQHYIPSPNPYRAADPADGQAIIDASVAALRAKVAELGAENVAAFFCEPIQGSGGVIVP
CCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCHHHEEEHEECCCCCCCCEEEC
PRGWLKAMCEAAHSLDILFVVDEVITGFGRTGPMFACQAEGVEPDLMTVAKGLTSGYVPM
CHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCH
GATLMSHRIYSAIADGAPRGAPIGHGATYSAHPVSAAVALEVLRLYDEGGILANGQRVAA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHH
AFAQGLDDLLAHPLVGDSRHRGLLGALELVSSKTTKAGFDAALDLPARMAATSYRNGIVF
HHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHCCCEEE
RAFGDNILGFAPALTFTESDFGLMFERVKKTLDDVLAVPEVRAALKD
EECCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]