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The map label for this gene is dadA2 [H]

Identifier: 120610616

GI number: 120610616

Start: 2098812

End: 2100101

Strand: Reverse

Name: dadA2 [H]

Synonym: Aave_1936

Alternate gene names: 120610616

Gene position: 2100101-2098812 (Counterclockwise)

Preceding gene: 120610618

Following gene: 120610614

Centisome position: 39.23

GC content: 73.33

Gene sequence:

>1290_bases
ATGGGAATGGACAGGCATGCATGCATTCTGGGCGCGGGGATCGCGGGCCTGGCGACGGCCTATGCGCTGCAGCGGCAGGG
CTGGCAGGTCACGGTGATCGACCAGGGGCCGGTGGGCGGCGGCGCGAGCGGCGGCAACGGCGCGCAGCTCAGCTACAGCT
ACGTGCAGCCGCTCGCCGACGCCTCCGTCTGGGGGCAGTTGCCCAAGCTCCTCTTCTCGCCGGATTCGCCGCTCAAGCTG
CGGCCGCAGTGGAGCCTGCACCAGTGGCGCTGGGGTGCCGCCTTCCTCGCGGCCTGCAACGACACGACCTCGCGCAGTAC
CACGGGCGCGCTGCTGGCGCTCGCCGCCCGCAGCCGCGTGGCATTCGAGGGCTTGCTGGAGCGCGAAGGAATCGCCTGCG
ACTTCACGCGCACGGGCAAGCTGGTGGTGTACCGCTCGCCCGAATCCCTGGCCGCCGCCGAGCGGCAGATGGCGCTGCAG
CGCGCCTGGGGCTGCGAGCAGGAATCCGTCTCCGCCGCGCGCTGCGTGGAGCTGGAGCCCGCGCTCGCCCACGGCACCGA
CCGCATCGCGGGCGCCATCTACACGCCCAGCGAATGCGCGGCCGATTGCCGCAAGGTCTGCGAAGGGCTGCAGGCACTGC
TGGCAGCGCGGGGTGTGCGCTTCGTGCTGGACGCACAGCTGCGCGGCTTCGATCGCAGGGCCGACGGCCGCATCGCCGCG
GTGCAGTTGCGGCGCGCGGGCAGCATGGAGGACGTGCGCATGGAAGCCGACCACTTCGTGCTGGCCCTGGGCAGTGCCAG
CGCCGCCTGGGCCGCGCGGCTGGGCATGCGGCTGCCCGTGTACCCGCTCAAGGGCTACAGCCTCACGCTCGATGCGCCCG
CCGATGCGGCCTGGGCTCCGCACGTGAACGTGACCGACGCGGCACGCAAGGTGGTGTTCGCCCGCCTGGGCGACCGGCTG
CGCGTGGCGGGCATGGCTGAACTCGTGGGCGATGACCGCAGCATTCCGCAGGACCGCATCGACCGCCTGCGCCAAGCCGT
GGTGGAGGTGTTCGGCCACGACCCGGGCGCCGACGCACCGCTGCGCCCCTGGACGGGCATGCGCCCTGCTACGCCGACGG
GCCTGCCCATGGTGGGACGGCAGCCGGGCGGACCCGCCAACGGCTGGCTGCACACGGGCCACGGCGCCCTGGGGTTCACG
CTCTCGTTCGGCACCGCGGAGCAATTGGCGGAGGCGATGGCGCAGGCGCCGCAGGCCACCGCCGTACCGGGCGCCGTTCA
CGCCGCCTGA

Upstream 100 bases:

>100_bases
CATGGACGCCCGGGCGAACGGCATTGTTCAAGCCGCGGGCACCGCCCTACAGTCTTGCCGATGTGCCGGCTGGCATCGAA
TGGAATGGACGGGACGAACG

Downstream 100 bases:

>100_bases
GCCGGCCCCTTCTGCACGGTCTGCAGCACGGCCTCGCGCATGCAGCGCACCATCGCATCGGCGAGCAGCGATGCCGGGCG
GTGCGGCATGCGCAGCGCCC

Product: D-amino-acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MGMDRHACILGAGIAGLATAYALQRQGWQVTVIDQGPVGGGASGGNGAQLSYSYVQPLADASVWGQLPKLLFSPDSPLKL
RPQWSLHQWRWGAAFLAACNDTTSRSTTGALLALAARSRVAFEGLLEREGIACDFTRTGKLVVYRSPESLAAAERQMALQ
RAWGCEQESVSAARCVELEPALAHGTDRIAGAIYTPSECAADCRKVCEGLQALLAARGVRFVLDAQLRGFDRRADGRIAA
VQLRRAGSMEDVRMEADHFVLALGSASAAWAARLGMRLPVYPLKGYSLTLDAPADAAWAPHVNVTDAARKVVFARLGDRL
RVAGMAELVGDDRSIPQDRIDRLRQAVVEVFGHDPGADAPLRPWTGMRPATPTGLPMVGRQPGGPANGWLHTGHGALGFT
LSFGTAEQLAEAMAQAPQATAVPGAVHAA

Sequences:

>Translated_429_residues
MGMDRHACILGAGIAGLATAYALQRQGWQVTVIDQGPVGGGASGGNGAQLSYSYVQPLADASVWGQLPKLLFSPDSPLKL
RPQWSLHQWRWGAAFLAACNDTTSRSTTGALLALAARSRVAFEGLLEREGIACDFTRTGKLVVYRSPESLAAAERQMALQ
RAWGCEQESVSAARCVELEPALAHGTDRIAGAIYTPSECAADCRKVCEGLQALLAARGVRFVLDAQLRGFDRRADGRIAA
VQLRRAGSMEDVRMEADHFVLALGSASAAWAARLGMRLPVYPLKGYSLTLDAPADAAWAPHVNVTDAARKVVFARLGDRL
RVAGMAELVGDDRSIPQDRIDRLRQAVVEVFGHDPGADAPLRPWTGMRPATPTGLPMVGRQPGGPANGWLHTGHGALGFT
LSFGTAEQLAEAMAQAPQATAVPGAVHAA
>Mature_428_residues
GMDRHACILGAGIAGLATAYALQRQGWQVTVIDQGPVGGGASGGNGAQLSYSYVQPLADASVWGQLPKLLFSPDSPLKLR
PQWSLHQWRWGAAFLAACNDTTSRSTTGALLALAARSRVAFEGLLEREGIACDFTRTGKLVVYRSPESLAAAERQMALQR
AWGCEQESVSAARCVELEPALAHGTDRIAGAIYTPSECAADCRKVCEGLQALLAARGVRFVLDAQLRGFDRRADGRIAAV
QLRRAGSMEDVRMEADHFVLALGSASAAWAARLGMRLPVYPLKGYSLTLDAPADAAWAPHVNVTDAARKVVFARLGDRLR
VAGMAELVGDDRSIPQDRIDRLRQAVVEVFGHDPGADAPLRPWTGMRPATPTGLPMVGRQPGGPANGWLHTGHGALGFTL
SFGTAEQLAEAMAQAPQATAVPGAVHAA

Specific function: Oxidative deamination of D-amino acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787438, Length=412, Percent_Identity=31.3106796116505, Blast_Score=189, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023080
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.99.1 [H]

Molecular weight: Translated: 45443; Mature: 45312

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMDRHACILGAGIAGLATAYALQRQGWQVTVIDQGPVGGGASGGNGAQLSYSYVQPLAD
CCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHH
ASVWGQLPKLLFSPDSPLKLRPQWSLHQWRWGAAFLAACNDTTSRSTTGALLALAARSRV
HHHHHHHHHHHCCCCCCCEECCCCCCHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHH
AFEGLLEREGIACDFTRTGKLVVYRSPESLAAAERQMALQRAWGCEQESVSAARCVELEP
HHHHHHHCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHCCCCHHHCCHHHEEECCH
ALAHGTDRIAGAIYTPSECAADCRKVCEGLQALLAARGVRFVLDAQLRGFDRRADGRIAA
HHHCCCHHHCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCCEEE
VQLRRAGSMEDVRMEADHFVLALGSASAAWAARLGMRLPVYPLKGYSLTLDAPADAAWAP
EEEHHCCCHHHHEECCCEEEEEECCCCHHHHHHHCCCCCCEECCCEEEEECCCCCCCCCC
HVNVTDAARKVVFARLGDRLRVAGMAELVGDDRSIPQDRIDRLRQAVVEVFGHDPGADAP
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
LRPWTGMRPATPTGLPMVGRQPGGPANGWLHTGHGALGFTLSFGTAEQLAEAMAQAPQAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEEEEECCCHHHHHHHHHCCCCCC
AVPGAVHAA
CCCCHHCCC
>Mature Secondary Structure 
GMDRHACILGAGIAGLATAYALQRQGWQVTVIDQGPVGGGASGGNGAQLSYSYVQPLAD
CCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHH
ASVWGQLPKLLFSPDSPLKLRPQWSLHQWRWGAAFLAACNDTTSRSTTGALLALAARSRV
HHHHHHHHHHHCCCCCCCEECCCCCCHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHH
AFEGLLEREGIACDFTRTGKLVVYRSPESLAAAERQMALQRAWGCEQESVSAARCVELEP
HHHHHHHCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHCCCCHHHCCHHHEEECCH
ALAHGTDRIAGAIYTPSECAADCRKVCEGLQALLAARGVRFVLDAQLRGFDRRADGRIAA
HHHCCCHHHCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCCEEE
VQLRRAGSMEDVRMEADHFVLALGSASAAWAARLGMRLPVYPLKGYSLTLDAPADAAWAP
EEEHHCCCHHHHEECCCEEEEEECCCCHHHHHHHCCCCCCEECCCEEEEECCCCCCCCCC
HVNVTDAARKVVFARLGDRLRVAGMAELVGDDRSIPQDRIDRLRQAVVEVFGHDPGADAP
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
LRPWTGMRPATPTGLPMVGRQPGGPANGWLHTGHGALGFTLSFGTAEQLAEAMAQAPQAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEEEEECCCHHHHHHHHHCCCCCC
AVPGAVHAA
CCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]