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The map label for this gene is orn

Identifier: 120610573

GI number: 120610573

Start: 2048191

End: 2048772

Strand: Direct

Name: orn

Synonym: Aave_1893

Alternate gene names: 120610573

Gene position: 2048191-2048772 (Clockwise)

Preceding gene: 120610569

Following gene: 120610574

Centisome position: 38.26

GC content: 64.6

Gene sequence:

>582_bases
ATGTCCGATACCGCACCCGTCTCCGTCCCTCCCGTCCTTCCCAAATCCGACCTGAACTTCGTCTGGCTCGACTGCGAGAT
GACGGGGCTCGATCCCGAGAAGGATCGCCTGCTGGAGATCGCCGTCGTGGTCACCGGTCCGGAACTGGAGCCGCGGGTGG
AGGGGCCGGTGTTCGCCATCCACCAGTCCGATGCGTTGCTCGACGGCATGGATGCCTGGAACAAGGGCACGCACGGTCGC
AGCGGTCTCATCGAGAAGGTGCGGGCCTCCACGGTCACGGAGGCCGAGGCCGAACAGGCCATCCTGGAATTTCTCGCGCG
GTATGTGCGCAAGGGCGTGGCACCCATGTGCGGCAACAGCATCGGCCAGGACCGGCGTTTCCTCGTGCGCTACATGCCGA
AGCTGGAGGCGTTCTTCCATTACCGCAACGTGGACGTGAGCACCCTCAAGGAGCTGTCCCGGCGCTGGAAGCCCGAGGTG
TACGCCAGCTTCAAGAAGGCGCAGAAGCACACCGCGCTCGCCGATGTGCACGAATCCATCGAGGAACTGGCGCACTACCG
CAAGCACCTGCTGGTGCCCTGA

Upstream 100 bases:

>100_bases
GAGGCGGTATCGGGGGCGGGAGGCATGTACCGGGAGTTTAGGGCTTCGCGGACCGGCATCGCGGCGGCAGGGGCGTTCCG
CCTGGGAGACAATCCGGGCC

Downstream 100 bases:

>100_bases
CCGCGGCCGTTTGCGGGAAAACCCGAATCGTGCGATAATTGCAGGCTTGCGCGGAAAAACATCGGATGCAACTTCCGGTC
CGCGCGATTTGCGCATCTCC

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSDTAPVSVPPVLPKSDLNFVWLDCEMTGLDPEKDRLLEIAVVVTGPELEPRVEGPVFAIHQSDALLDGMDAWNKGTHGR
SGLIEKVRASTVTEAEAEQAILEFLARYVRKGVAPMCGNSIGQDRRFLVRYMPKLEAFFHYRNVDVSTLKELSRRWKPEV
YASFKKAQKHTALADVHESIEELAHYRKHLLVP

Sequences:

>Translated_193_residues
MSDTAPVSVPPVLPKSDLNFVWLDCEMTGLDPEKDRLLEIAVVVTGPELEPRVEGPVFAIHQSDALLDGMDAWNKGTHGR
SGLIEKVRASTVTEAEAEQAILEFLARYVRKGVAPMCGNSIGQDRRFLVRYMPKLEAFFHYRNVDVSTLKELSRRWKPEV
YASFKKAQKHTALADVHESIEELAHYRKHLLVP
>Mature_192_residues
SDTAPVSVPPVLPKSDLNFVWLDCEMTGLDPEKDRLLEIAVVVTGPELEPRVEGPVFAIHQSDALLDGMDAWNKGTHGRS
GLIEKVRASTVTEAEAEQAILEFLARYVRKGVAPMCGNSIGQDRRFLVRYMPKLEAFFHYRNVDVSTLKELSRRWKPEVY
ASFKKAQKHTALADVHESIEELAHYRKHLLVP

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=173, Percent_Identity=47.3988439306358, Blast_Score=166, Evalue=1e-41,
Organism=Escherichia coli, GI87082382, Length=173, Percent_Identity=58.9595375722543, Blast_Score=224, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17557752, Length=178, Percent_Identity=46.0674157303371, Blast_Score=165, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6323088, Length=183, Percent_Identity=40.4371584699454, Blast_Score=126, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21355135, Length=176, Percent_Identity=43.75, Blast_Score=167, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_ACIAC (A1TND9)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_970251.1
- ProteinModelPortal:   A1TND9
- SMR:   A1TND9
- STRING:   A1TND9
- GeneID:   4668262
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_1893
- NMPDR:   fig|397945.5.peg.1641
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- PhylomeDB:   A1TND9
- ProtClustDB:   PRK05359
- BioCyc:   AAVE397945:AAVE_1893-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 21780; Mature: 21649

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: ACT_SITE 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTAPVSVPPVLPKSDLNFVWLDCEMTGLDPEKDRLLEIAVVVTGPELEPRVEGPVFAI
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHCEEEEEEEEECCCCCCCCCCCEEEE
HQSDALLDGMDAWNKGTHGRSGLIEKVRASTVTEAEAEQAILEFLARYVRKGVAPMCGNS
ECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IGQDRRFLVRYMPKLEAFFHYRNVDVSTLKELSRRWKPEVYASFKKAQKHTALADVHESI
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EELAHYRKHLLVP
HHHHHHHHHCCCC
>Mature Secondary Structure 
SDTAPVSVPPVLPKSDLNFVWLDCEMTGLDPEKDRLLEIAVVVTGPELEPRVEGPVFAI
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHCEEEEEEEEECCCCCCCCCCCEEEE
HQSDALLDGMDAWNKGTHGRSGLIEKVRASTVTEAEAEQAILEFLARYVRKGVAPMCGNS
ECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IGQDRRFLVRYMPKLEAFFHYRNVDVSTLKELSRRWKPEVYASFKKAQKHTALADVHESI
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EELAHYRKHLLVP
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA