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The map label for this gene is murB [H]

Identifier: 120610535

GI number: 120610535

Start: 2010341

End: 2011414

Strand: Direct

Name: murB [H]

Synonym: Aave_1855

Alternate gene names: 120610535

Gene position: 2010341-2011414 (Clockwise)

Preceding gene: 120610531

Following gene: 120610540

Centisome position: 37.56

GC content: 70.76

Gene sequence:

>1074_bases
ATGTTAGTCGAGAAAAACGTCCCCCTGCAGGCCTGCAACACCTTCGGCATCGTGGCGCGCGCCCATACGCTGGTGCGTGC
GCGCTCGGCCGGCGACGTGCGGGCGCTGCTCGCCGATCCGCAACTCGGCGCCGGCCCGCTGTTCGTGCTGGGCGGGGGCA
GCAACATCGTGCTCACGGGCGACGTGAAGCCCGTCGTGCTCAAGATGGAGATCCCGGGCATCCGCCTGGTCGAGGAAACC
CCGCGCGCCTGGATCGTGGAGGCCGGCGCGGGCGAGCGCTGGCACGACGCGGTCGCCTGGACGCTCGAGCATGGCTTTCC
GGGGCTGGAGAACCTGGCCCTCATTCCCGGCACCGTGGGCGCCGCCCCCGTGCAGAACATCGGCGCGTACGGCGTCGAGC
TGCAGGACCGTTTCGACTCGCTGGACGCCATCGACCTCGCCACGGGCCGCCCGTTCTCGCTGGACGCCGCCCAGTGCGCC
TTCGGCTACCGCGACTCCGTCTTCAAGCACGCGCCCGCCGGCAACGGGGCCGATACCGGCCTGCCCCGGGGGATGGGCCT
GGCGGGCCGGGCGGTCATCACCCATGTCCGCTTCCGCCTGCCCAAGCCCTGGAGGCCCGAACTGGGCTACCTGGACCTGG
AGCGCAAGCGCCAGGAGGCGGGCGTGGAGCAGCCCACGGCCCGCCAGATCTTCGACTGGGTGTGCGAGGTGCGCCGCGCC
AAGCTGCCCGATCCGGCCGTGCTCGGCAATGCCGGCAGCTTCTTCAAGAACCCGACCGTGACGCCGGAGCAGTGCTCGGA
CATCATCGCGCGCGACCCCAAGATCGTGCACTACCCGATGCCGGACGGCACCATCAAGCTCGCGGCCGGCTGGCTCATCG
ATGCCTGCGGCTGGAAGGGCAAGACCGTCGGCAAGGCCGGCGTGTACGAGAAGCAGGCCCTGGTGCTGGTCAACCGCGGC
CGCGGTGGCGACAGCGTCACGGGCGGCGAGGTGATGACGCTGGCCAAGGCCATCCAGACGAGCGTCTATGAGCGCTTCGG
CATCCGGCTCGAACCCGAGCCGGTCGTGGTCTGA

Upstream 100 bases:

>100_bases
GGTTGGCTTCACAGACGGTATCAAAAGAAGGCATGGCTTCGCTCTCGGTATCTCGGGTGGGGGGCCTCGCCGGCGAGGCC
CGAATGCGACAATCCGGTGG

Downstream 100 bases:

>100_bases
GCCGGCCGCGAGGTCCGGGCCGCCGGACGTGAAAAAACCGCCCGGCCTTGCGGCGGAGCGGTTTCTCCGGGAGCGTGCCT
GCCGCGGACGGCAGGGCCGC

Product: UDP-N-acetylmuramate dehydrogenase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MLVEKNVPLQACNTFGIVARAHTLVRARSAGDVRALLADPQLGAGPLFVLGGGSNIVLTGDVKPVVLKMEIPGIRLVEET
PRAWIVEAGAGERWHDAVAWTLEHGFPGLENLALIPGTVGAAPVQNIGAYGVELQDRFDSLDAIDLATGRPFSLDAAQCA
FGYRDSVFKHAPAGNGADTGLPRGMGLAGRAVITHVRFRLPKPWRPELGYLDLERKRQEAGVEQPTARQIFDWVCEVRRA
KLPDPAVLGNAGSFFKNPTVTPEQCSDIIARDPKIVHYPMPDGTIKLAAGWLIDACGWKGKTVGKAGVYEKQALVLVNRG
RGGDSVTGGEVMTLAKAIQTSVYERFGIRLEPEPVVV

Sequences:

>Translated_357_residues
MLVEKNVPLQACNTFGIVARAHTLVRARSAGDVRALLADPQLGAGPLFVLGGGSNIVLTGDVKPVVLKMEIPGIRLVEET
PRAWIVEAGAGERWHDAVAWTLEHGFPGLENLALIPGTVGAAPVQNIGAYGVELQDRFDSLDAIDLATGRPFSLDAAQCA
FGYRDSVFKHAPAGNGADTGLPRGMGLAGRAVITHVRFRLPKPWRPELGYLDLERKRQEAGVEQPTARQIFDWVCEVRRA
KLPDPAVLGNAGSFFKNPTVTPEQCSDIIARDPKIVHYPMPDGTIKLAAGWLIDACGWKGKTVGKAGVYEKQALVLVNRG
RGGDSVTGGEVMTLAKAIQTSVYERFGIRLEPEPVVV
>Mature_357_residues
MLVEKNVPLQACNTFGIVARAHTLVRARSAGDVRALLADPQLGAGPLFVLGGGSNIVLTGDVKPVVLKMEIPGIRLVEET
PRAWIVEAGAGERWHDAVAWTLEHGFPGLENLALIPGTVGAAPVQNIGAYGVELQDRFDSLDAIDLATGRPFSLDAAQCA
FGYRDSVFKHAPAGNGADTGLPRGMGLAGRAVITHVRFRLPKPWRPELGYLDLERKRQEAGVEQPTARQIFDWVCEVRRA
KLPDPAVLGNAGSFFKNPTVTPEQCSDIIARDPKIVHYPMPDGTIKLAAGWLIDACGWKGKTVGKAGVYEKQALVLVNRG
RGGDSVTGGEVMTLAKAIQTSVYERFGIRLEPEPVVV

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=351, Percent_Identity=44.4444444444444, Blast_Score=276, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 38335; Mature: 38335

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVEKNVPLQACNTFGIVARAHTLVRARSAGDVRALLADPQLGAGPLFVLGGGSNIVLTG
CCCCCCCCHHHHCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEC
DVKPVVLKMEIPGIRLVEETPRAWIVEAGAGERWHDAVAWTLEHGFPGLENLALIPGTVG
CCCEEEEEEECCCEEEEECCCCEEEEECCCCCCCHHHEEEEEECCCCCCCCEEECCCCCC
AAPVQNIGAYGVELQDRFDSLDAIDLATGRPFSLDAAQCAFGYRDSVFKHAPAGNGADTG
CCCHHHCCCCCCCHHHHHCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCC
LPRGMGLAGRAVITHVRFRLPKPWRPELGYLDLERKRQEAGVEQPTARQIFDWVCEVRRA
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHC
KLPDPAVLGNAGSFFKNPTVTPEQCSDIIARDPKIVHYPMPDGTIKLAAGWLIDACGWKG
CCCCCCEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEEEECEEEECCCCCC
KTVGKAGVYEKQALVLVNRGRGGDSVTGGEVMTLAKAIQTSVYERFGIRLEPEPVVV
CCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEECCCCCCC
>Mature Secondary Structure
MLVEKNVPLQACNTFGIVARAHTLVRARSAGDVRALLADPQLGAGPLFVLGGGSNIVLTG
CCCCCCCCHHHHCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEC
DVKPVVLKMEIPGIRLVEETPRAWIVEAGAGERWHDAVAWTLEHGFPGLENLALIPGTVG
CCCEEEEEEECCCEEEEECCCCEEEEECCCCCCCHHHEEEEEECCCCCCCCEEECCCCCC
AAPVQNIGAYGVELQDRFDSLDAIDLATGRPFSLDAAQCAFGYRDSVFKHAPAGNGADTG
CCCHHHCCCCCCCHHHHHCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCC
LPRGMGLAGRAVITHVRFRLPKPWRPELGYLDLERKRQEAGVEQPTARQIFDWVCEVRRA
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHC
KLPDPAVLGNAGSFFKNPTVTPEQCSDIIARDPKIVHYPMPDGTIKLAAGWLIDACGWKG
CCCCCCEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEEEECEEEECCCCCC
KTVGKAGVYEKQALVLVNRGRGGDSVTGGEVMTLAKAIQTSVYERFGIRLEPEPVVV
CCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA