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The map label for this gene is fabZ

Identifier: 120610514

GI number: 120610514

Start: 1988935

End: 1989375

Strand: Direct

Name: fabZ

Synonym: Aave_1834

Alternate gene names: 120610514

Gene position: 1988935-1989375 (Clockwise)

Preceding gene: 120610513

Following gene: 120610515

Centisome position: 37.16

GC content: 64.4

Gene sequence:

>441_bases
ATGATGGACATCCACCAAATCCTCAAGCTCCTGCCGCACCGCTATCCCTTCCTGCTGGTGGACCGTGTCGTCGAACTCGA
AAGGGGCGAGCGCATCCAGGCGATCAAGAACGTCACGATCAACGAGCCGTTCTTCACCGGGCATTTCCCGAACCGGCCGG
TCATGCCCGGCGTGCTGATGCTGGAAGCCCTCGCCCAGGCGGCGGGCCTGCTGTCCTTCGACATGATGGGCGAGGCCCCT
GGCGACGACAAGGTGTTCTACTTCGTCGGCATCGACGGTGCGCGTTTCAAGCGGCCCGTGGAGCCTGGCGACCAGCTCAT
CCTCGACGTGAAGCTCGACCGCATCAAGGGCGGCATCTACAAGTTCGGCGGCGTGGCGCGCGTGGGCGACAGCGTGGCCT
GCGAAGCCGAGATCATGTGCACCATGCGGACCGTCGCCTGA

Upstream 100 bases:

>100_bases
AAAAGAACGCGGCCACGCTGCGCCAGCTCCACGGGCTGCGCGCGCGCATCATGGCCCTCGAAGAACAGATACGAAAAGAC
GGTCCCACCGCACATATCCA

Downstream 100 bases:

>100_bases
AGGGCTGAGGGCGCGGGACCATGAGCAGCATCCATTCCACGGCCATCGTCGATCCGGGCGCCGAGCTGGACAGCTCGGTC
ACCGTCGGCCCCTATGCGGT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MMDIHQILKLLPHRYPFLLVDRVVELERGERIQAIKNVTINEPFFTGHFPNRPVMPGVLMLEALAQAAGLLSFDMMGEAP
GDDKVFYFVGIDGARFKRPVEPGDQLILDVKLDRIKGGIYKFGGVARVGDSVACEAEIMCTMRTVA

Sequences:

>Translated_146_residues
MMDIHQILKLLPHRYPFLLVDRVVELERGERIQAIKNVTINEPFFTGHFPNRPVMPGVLMLEALAQAAGLLSFDMMGEAP
GDDKVFYFVGIDGARFKRPVEPGDQLILDVKLDRIKGGIYKFGGVARVGDSVACEAEIMCTMRTVA
>Mature_146_residues
MMDIHQILKLLPHRYPFLLVDRVVELERGERIQAIKNVTINEPFFTGHFPNRPVMPGVLMLEALAQAAGLLSFDMMGEAP
GDDKVFYFVGIDGARFKRPVEPGDQLILDVKLDRIKGGIYKFGGVARVGDSVACEAEIMCTMRTVA

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=140, Percent_Identity=55.7142857142857, Blast_Score=170, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_ACIAC (A1TN80)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_970192.1
- ProteinModelPortal:   A1TN80
- SMR:   A1TN80
- STRING:   A1TN80
- GeneID:   4669904
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_1834
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   A1TN80
- ProtClustDB:   PRK00006
- BioCyc:   AAVE397945:AAVE_1834-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16263; Mature: 16263

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDIHQILKLLPHRYPFLLVDRVVELERGERIQAIKNVTINEPFFTGHFPNRPVMPGVLM
CCCHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCEEECCCCCCCCCCHHHH
LEALAQAAGLLSFDMMGEAPGDDKVFYFVGIDGARFKRPVEPGDQLILDVKLDRIKGGIY
HHHHHHHHCCCEEECCCCCCCCCEEEEEEECCCHHCCCCCCCCCEEEEEEEEHHHCCCCC
KFGGVARVGDSVACEAEIMCTMRTVA
CCCCCHHCCCCCCCCHHEEEEEEECC
>Mature Secondary Structure
MMDIHQILKLLPHRYPFLLVDRVVELERGERIQAIKNVTINEPFFTGHFPNRPVMPGVLM
CCCHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCEEECCCCCCCCCCHHHH
LEALAQAAGLLSFDMMGEAPGDDKVFYFVGIDGARFKRPVEPGDQLILDVKLDRIKGGIY
HHHHHHHHCCCEEECCCCCCCCCEEEEEEECCCHHCCCCCCCCCEEEEEEEEHHHCCCCC
KFGGVARVGDSVACEAEIMCTMRTVA
CCCCCHHCCCCCCCCHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA