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The map label for this gene is cdsA [H]

Identifier: 120610508

GI number: 120610508

Start: 1981599

End: 1982453

Strand: Direct

Name: cdsA [H]

Synonym: Aave_1828

Alternate gene names: 120610508

Gene position: 1981599-1982453 (Clockwise)

Preceding gene: 120610507

Following gene: 120610509

Centisome position: 37.02

GC content: 73.33

Gene sequence:

>855_bases
ATGCTGGTCACGCGCATCCTCACGGCCATCGTCCTGCTGGCCATCCTGTTGCCGGCGCTCTTCGCCGGCTCGGTCGTGCC
TTTCGCGGCCGTGGTGCTGGTGCTCATGGCCGCCGGCGGCTGGGAGTGGGGCCGGCTGCAGGGCCTGGGCCAGCCGGCGT
CCCTGGCGGTGGGCGCGGCCTGCGTGCTGCTCTGCGCCGCGAGCTGGGCGGGCGGCTGGACGGAGCGTCCGCTGACCTGG
CTCTGGGCCGCCGCCGGCGCCGGCTGGGTGCTGTGCGGCGCCTGGCTGCTGCGCCATGGCGTGGAGGGCTGGCCGCGCAT
TCCCCATCCCGTGCGCCTGGCCGGCGGGGTGCTGGCCCTCTGGCTGGCGTGGCTGGCCGCCGTGCAGGCGCGCACCATCG
GCATCAATTTCCTGCTGTCCGTGCTCGTGCTGGTCTGGGTCGCGGACATCTTCGCCTATTTCGCCGGCCGGGCGTTCGGC
CTGCGCTTCACGCGTTCCAAGCTGGCGCCTTCCATCAGCCCCGGCAAGAGCTGGGAAGGCGTCTGGGGCGGCATGGCCGG
CGTGATCGTGCTCGCCCTGGCCTGGGCGGCGGCCGATGCCGCCTCGCAGGCCCCGGTCCCGAGCTTCTACTCGCGGCTGG
CCGCCAAGGGCTGGTGGCTGCTGGTCATCGGCGCGGTGTTCATGGCCTGCATGAGCGTGGTGGGCGATCTCGTCGAATCG
CTGGTCAAGCGCAGCGCGGGCGCCAAGGACAGCAGCCGGCTGCTGCCCGGCCACGGCGGCGTGCTCGACCGGGTGGACGC
GCTGCTGCCCACGCTGCCCCTGGCCATGATGCTCACCCATTTCGCTGCCCCATGA

Upstream 100 bases:

>100_bases
CCATCGCCGCCTACGGGGCACGCGAGCGCCGGTTCGGCAAGACATCCGAGCAACTGCTGGCCTCCCCGACCTCGTCGGCG
TGCGCCTGAAGGGGTTTCCC

Downstream 100 bases:

>100_bases
AACAACGCCTTACCGTCCTGGGTTCCACCGGCTCCATCGGAACCAGTACCCTGGACGTGGTCGCGCGCCACCCCGGCCGC
TACGAGATCTTCGCGCTGAG

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MLVTRILTAIVLLAILLPALFAGSVVPFAAVVLVLMAAGGWEWGRLQGLGQPASLAVGAACVLLCAASWAGGWTERPLTW
LWAAAGAGWVLCGAWLLRHGVEGWPRIPHPVRLAGGVLALWLAWLAAVQARTIGINFLLSVLVLVWVADIFAYFAGRAFG
LRFTRSKLAPSISPGKSWEGVWGGMAGVIVLALAWAAADAASQAPVPSFYSRLAAKGWWLLVIGAVFMACMSVVGDLVES
LVKRSAGAKDSSRLLPGHGGVLDRVDALLPTLPLAMMLTHFAAP

Sequences:

>Translated_284_residues
MLVTRILTAIVLLAILLPALFAGSVVPFAAVVLVLMAAGGWEWGRLQGLGQPASLAVGAACVLLCAASWAGGWTERPLTW
LWAAAGAGWVLCGAWLLRHGVEGWPRIPHPVRLAGGVLALWLAWLAAVQARTIGINFLLSVLVLVWVADIFAYFAGRAFG
LRFTRSKLAPSISPGKSWEGVWGGMAGVIVLALAWAAADAASQAPVPSFYSRLAAKGWWLLVIGAVFMACMSVVGDLVES
LVKRSAGAKDSSRLLPGHGGVLDRVDALLPTLPLAMMLTHFAAP
>Mature_284_residues
MLVTRILTAIVLLAILLPALFAGSVVPFAAVVLVLMAAGGWEWGRLQGLGQPASLAVGAACVLLCAASWAGGWTERPLTW
LWAAAGAGWVLCGAWLLRHGVEGWPRIPHPVRLAGGVLALWLAWLAAVQARTIGINFLLSVLVLVWVADIFAYFAGRAFG
LRFTRSKLAPSISPGKSWEGVWGGMAGVIVLALAWAAADAASQAPVPSFYSRLAAKGWWLLVIGAVFMACMSVVGDLVES
LVKRSAGAKDSSRLLPGHGGVLDRVDALLPTLPLAMMLTHFAAP

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=291, Percent_Identity=35.7388316151203, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787677, Length=135, Percent_Identity=34.8148148148148, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29831; Mature: 29831

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]