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The map label for this gene is tsf

Identifier: 120610504

GI number: 120610504

Start: 1978518

End: 1979414

Strand: Direct

Name: tsf

Synonym: Aave_1824

Alternate gene names: 120610504

Gene position: 1978518-1979414 (Clockwise)

Preceding gene: 120610503

Following gene: 120610505

Centisome position: 36.96

GC content: 66.11

Gene sequence:

>897_bases
ATGGCTGCAATTACCGCTAGCATGGTTGCCGAACTGCGCGCCAAGACCGACGCTCCCATGATGGAGTGCAAGAAGGCCCT
GACGGAAGCCGACGGCGACCTGGCCAAGGCCGAGGAGCTGCTGCGCGTCAAGCTGGGCACCAAGGCTGGCAAGGCTGCCG
CCCGCATCACCGCCGAAGGCGTGGTCGCCAGCTTCATCGAGGGCACGACCGGCGCCCTGATCGAAGTGAACAGCGAAACC
GACTTCGTGAGCAAGAACGACAGCTTCATCGCCCTGGCCAAGGCTGCGGCCGAGCTGGTCGCCAAGCACAACCCCGCCGA
CGTGGAAGCCCTGGGCGCGCTGCCCTACAGCCAGGAAAGCTTCGGCCCCACGCTGGAAGAAGTGCGCAAGGGCCTGATCG
GCAAGATCGGCGAGAACATGTCCTTCCGCCGCTTCAAGCGCTTCTCGGGCTCCAAGCTGGCTTCCTACCTGCACGGCACC
CGCATCGGCGTGGTGGTGGAGTTCGACGGCGACGAAACCGCCGCCAAGGACGTCGCGATGCACATCGCCGCCATGAAGCC
CGTGGCCCTGACCAGCGCCGACGTGCCCGCCGAGCTGATCGAGAAGGAGCGCACCGTCGCTGCCGCCAAGGCCGCCGAAT
CCGGCAAGCCTGCCGACATCGCCGCCAAGATGGTGGAAGGCTCGGTGCAGAAGTACCTCAAGGAAGTCTCGCTGTTCGAC
CAGGTCTTCGTGAAGGCCGCCGACGGCAAGCAGACCGTGGGCCAGATGCTCAAGGCCGCCAACACCACCGTGAAGGGCTT
CACGCTCTACGTCGTGGGCGAAGGCATCGAGAAGAAGGTGGACGACTTCGCGGCGGAAGTGGCCGCGCAGGTGGCCGCCG
CCAAGGCCGCTGCCTGA

Upstream 100 bases:

>100_bases
CCGGCCGCGCGACCTGTCGCGAATGAAAGAGGGGCTCCTGGTTAGCCCCCTTTTTTTTAGCCTTGAATCCTGTAACGAAC
TGAAATCTGGAGAATTACCG

Downstream 100 bases:

>100_bases
TCCCTGGTCCCGTACAGTTCCCCGATTCCACCACCCGAAGAGAAACGCCCATGTCCGTCGCCGCTCCAGCCCACAAGCGC
ATTCTGCTCAAGTTGTCTGG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MAAITASMVAELRAKTDAPMMECKKALTEADGDLAKAEELLRVKLGTKAGKAAARITAEGVVASFIEGTTGALIEVNSET
DFVSKNDSFIALAKAAAELVAKHNPADVEALGALPYSQESFGPTLEEVRKGLIGKIGENMSFRRFKRFSGSKLASYLHGT
RIGVVVEFDGDETAAKDVAMHIAAMKPVALTSADVPAELIEKERTVAAAKAAESGKPADIAAKMVEGSVQKYLKEVSLFD
QVFVKAADGKQTVGQMLKAANTTVKGFTLYVVGEGIEKKVDDFAAEVAAQVAAAKAAA

Sequences:

>Translated_298_residues
MAAITASMVAELRAKTDAPMMECKKALTEADGDLAKAEELLRVKLGTKAGKAAARITAEGVVASFIEGTTGALIEVNSET
DFVSKNDSFIALAKAAAELVAKHNPADVEALGALPYSQESFGPTLEEVRKGLIGKIGENMSFRRFKRFSGSKLASYLHGT
RIGVVVEFDGDETAAKDVAMHIAAMKPVALTSADVPAELIEKERTVAAAKAAESGKPADIAAKMVEGSVQKYLKEVSLFD
QVFVKAADGKQTVGQMLKAANTTVKGFTLYVVGEGIEKKVDDFAAEVAAQVAAAKAAA
>Mature_297_residues
AAITASMVAELRAKTDAPMMECKKALTEADGDLAKAEELLRVKLGTKAGKAAARITAEGVVASFIEGTTGALIEVNSETD
FVSKNDSFIALAKAAAELVAKHNPADVEALGALPYSQESFGPTLEEVRKGLIGKIGENMSFRRFKRFSGSKLASYLHGTR
IGVVVEFDGDETAAKDVAMHIAAMKPVALTSADVPAELIEKERTVAAAKAAESGKPADIAAKMVEGSVQKYLKEVSLFDQ
VFVKAADGKQTVGQMLKAANTTVKGFTLYVVGEGIEKKVDDFAAEVAAQVAAAKAAA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=231, Percent_Identity=31.6017316017316, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI291084500, Length=255, Percent_Identity=30.5882352941176, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI291084498, Length=129, Percent_Identity=36.4341085271318, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI291084502, Length=100, Percent_Identity=40, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786366, Length=290, Percent_Identity=47.9310344827586, Blast_Score=228, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17561440, Length=294, Percent_Identity=27.2108843537415, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19921466, Length=310, Percent_Identity=29.0322580645161, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_ACIAC (A1TN70)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_970182.1
- ProteinModelPortal:   A1TN70
- SMR:   A1TN70
- STRING:   A1TN70
- GeneID:   4665653
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_1824
- NMPDR:   fig|397945.5.peg.1578
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   A1TN70
- ProtClustDB:   PRK09377
- BioCyc:   AAVE397945:AAVE_1824-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31199; Mature: 31068

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAITASMVAELRAKTDAPMMECKKALTEADGDLAKAEELLRVKLGTKAGKAAARITAEG
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
VVASFIEGTTGALIEVNSETDFVSKNDSFIALAKAAAELVAKHNPADVEALGALPYSQES
HHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHH
FGPTLEEVRKGLIGKIGENMSFRRFKRFSGSKLASYLHGTRIGVVVEFDGDETAAKDVAM
CCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHCCCEEEEEEEECCCHHHHHHHHH
HIAAMKPVALTSADVPAELIEKERTVAAAKAAESGKPADIAAKMVEGSVQKYLKEVSLFD
HHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QVFVKAADGKQTVGQMLKAANTTVKGFTLYVVGEGIEKKVDDFAAEVAAQVAAAKAAA
HHHHHCCCCHHHHHHHHHHHCCEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AAITASMVAELRAKTDAPMMECKKALTEADGDLAKAEELLRVKLGTKAGKAAARITAEG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
VVASFIEGTTGALIEVNSETDFVSKNDSFIALAKAAAELVAKHNPADVEALGALPYSQES
HHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHH
FGPTLEEVRKGLIGKIGENMSFRRFKRFSGSKLASYLHGTRIGVVVEFDGDETAAKDVAM
CCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHCCCEEEEEEEECCCHHHHHHHHH
HIAAMKPVALTSADVPAELIEKERTVAAAKAAESGKPADIAAKMVEGSVQKYLKEVSLFD
HHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QVFVKAADGKQTVGQMLKAANTTVKGFTLYVVGEGIEKKVDDFAAEVAAQVAAAKAAA
HHHHHCCCCHHHHHHHHHHHCCEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA