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The map label for this gene is dppA [H]

Identifier: 120610345

GI number: 120610345

Start: 1823342

End: 1824160

Strand: Direct

Name: dppA [H]

Synonym: Aave_1662

Alternate gene names: 120610345

Gene position: 1823342-1824160 (Clockwise)

Preceding gene: 120610344

Following gene: 120610346

Centisome position: 34.06

GC content: 70.09

Gene sequence:

>819_bases
ATGAAAATCCTCATCTCCGTCGATATCGAAGGCGTGGCTGGTGTCTACCACCCCGAACAGGTGCGCGCCGGCAATCCGGA
ATACGAGCGCGCCCGGCGCCTCATGGCCGCCGAGGCGAATGCCGCCATCGCCGGGGCGTTCGACGGTGGCGCCGCCGAGG
TGTTCGTCAACGATTCGCACGGGGGCTTCCGCAACATGCCGCCGGACCTGCTCGATCCGCGCGCCCAGGCCATCCAGGGC
AAGCCGCGCTACCTGAGCATGGTGGCCGGCGTGGAGCTCGGCATGGATGGCGTGTGCTTCATCGGCTACCACGCGAAATC
GCGGGCCCACGGCATCCTGGCCCACACCATCAACAGCTTCGCGTTCGCCCGCATCGCGCTCAACGGGCGGGAGCTGGGCG
AGGCCGGCATCTACGGCGCCCTCGCCGGGGCCTACGGGGCGCCGGTCATCGCCGCTTCCGGCGACGATGCCTTCATCGCG
GAGACGCGCGAGCTGTTCCCGCACGCGCAGTTCGTGCAGACCAAGCGCGCCACGGGCGCCAACAGCGGCATCAGCCTGTC
GCCCGAGCGTGCCTGCGCGGCCATCCGCGAAGGCGTGTCCCGGGCCATGACCGCGGCCGGACAGGCCCGGCCTTTCCGCA
TCGACGGTCCGGTCACGGTCGATCTGGAGGCGCAGTCGGTGGCGCTGGCCGACCTGTTCTGCCAGTGGCCCGCGCTGGAG
CGCACGGCGCCCGACGCGCTGCGGTTCACCGCGCCCGATACCGAGTCGGCGGTGCGGATGGTCAATGGCCTCTCTGCCAT
GTCCAGTATGTTGAGGTAG

Upstream 100 bases:

>100_bases
CCGCGGCACGCTGCGGGACCTCCTCTCCCGGTCCGGCTGACTCCCCACGTCGCCGTCCTCCCACGCCCAACCCTTCCTTT
TTCGCCCAGTGCAGCGTTCC

Downstream 100 bases:

>100_bases
GCACTGAGAACACCCCCCTGAGCGGCTGCGCCGCTTCCATGCAACCGCCAGAGGCGGCAGCCCTTCGGGCACGTCCGAGC
CTGCGCAGGCAGGCTCGGAG

Product: D-aminopeptidase DppA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MKILISVDIEGVAGVYHPEQVRAGNPEYERARRLMAAEANAAIAGAFDGGAAEVFVNDSHGGFRNMPPDLLDPRAQAIQG
KPRYLSMVAGVELGMDGVCFIGYHAKSRAHGILAHTINSFAFARIALNGRELGEAGIYGALAGAYGAPVIAASGDDAFIA
ETRELFPHAQFVQTKRATGANSGISLSPERACAAIREGVSRAMTAAGQARPFRIDGPVTVDLEAQSVALADLFCQWPALE
RTAPDALRFTAPDTESAVRMVNGLSAMSSMLR

Sequences:

>Translated_272_residues
MKILISVDIEGVAGVYHPEQVRAGNPEYERARRLMAAEANAAIAGAFDGGAAEVFVNDSHGGFRNMPPDLLDPRAQAIQG
KPRYLSMVAGVELGMDGVCFIGYHAKSRAHGILAHTINSFAFARIALNGRELGEAGIYGALAGAYGAPVIAASGDDAFIA
ETRELFPHAQFVQTKRATGANSGISLSPERACAAIREGVSRAMTAAGQARPFRIDGPVTVDLEAQSVALADLFCQWPALE
RTAPDALRFTAPDTESAVRMVNGLSAMSSMLR
>Mature_272_residues
MKILISVDIEGVAGVYHPEQVRAGNPEYERARRLMAAEANAAIAGAFDGGAAEVFVNDSHGGFRNMPPDLLDPRAQAIQG
KPRYLSMVAGVELGMDGVCFIGYHAKSRAHGILAHTINSFAFARIALNGRELGEAGIYGALAGAYGAPVIAASGDDAFIA
ETRELFPHAQFVQTKRATGANSGISLSPERACAAIREGVSRAMTAAGQARPFRIDGPVTVDLEAQSVALADLFCQWPALE
RTAPDALRFTAPDTESAVRMVNGLSAMSSMLR

Specific function: Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear [H]

COG id: COG2362

COG function: function code E; D-aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M55 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007035 [H]

Pfam domain/function: PF04951 Peptidase_M55 [H]

EC number: NA

Molecular weight: Translated: 28687; Mature: 28687

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILISVDIEGVAGVYHPEQVRAGNPEYERARRLMAAEANAAIAGAFDGGAAEVFVNDSH
CEEEEEECCCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCC
GGFRNMPPDLLDPRAQAIQGKPRYLSMVAGVELGMDGVCFIGYHAKSRAHGILAHTINSF
CCCCCCCHHHCCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHH
AFARIALNGRELGEAGIYGALAGAYGAPVIAASGDDAFIAETRELFPHAQFVQTKRATGA
EEEEEEECCCHHCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCC
NSGISLSPERACAAIREGVSRAMTAAGQARPFRIDGPVTVDLEAQSVALADLFCQWPALE
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEECHHHHHHHHHHHCCCCCC
RTAPDALRFTAPDTESAVRMVNGLSAMSSMLR
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKILISVDIEGVAGVYHPEQVRAGNPEYERARRLMAAEANAAIAGAFDGGAAEVFVNDSH
CEEEEEECCCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCC
GGFRNMPPDLLDPRAQAIQGKPRYLSMVAGVELGMDGVCFIGYHAKSRAHGILAHTINSF
CCCCCCCHHHCCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHH
AFARIALNGRELGEAGIYGALAGAYGAPVIAASGDDAFIAETRELFPHAQFVQTKRATGA
EEEEEEECCCHHCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCC
NSGISLSPERACAAIREGVSRAMTAAGQARPFRIDGPVTVDLEAQSVALADLFCQWPALE
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEECHHHHHHHHHHHCCCCCC
RTAPDALRFTAPDTESAVRMVNGLSAMSSMLR
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]