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The map label for this gene is cobT [H]

Identifier: 120610238

GI number: 120610238

Start: 1720127

End: 1721200

Strand: Direct

Name: cobT [H]

Synonym: Aave_1553

Alternate gene names: 120610238

Gene position: 1720127-1721200 (Clockwise)

Preceding gene: 120610237

Following gene: 120610241

Centisome position: 32.14

GC content: 75.42

Gene sequence:

>1074_bases
ATGACCACGAATGACCCCACCCCGGCCGGCGCCACGGTGCGCCCGCAGGATGCAGCCCTGGCCGCGCGCCTGCGCCACCG
CATGGACCACAAGACCAAACCGCTGGGCGCGCTCGGCCGGCTCGAGGCGCTGGCCGTGCGCATCGGCTGCATCTTTGGCA
CCGAATCGCCGGAGCTGCACGCGCCGCAGATGCTGGTCTGCGCGGCGGACCACGGCATCGCCGCGCGCGGCGTCTCCGCC
TATCCCAGCGAAGTCACCGCCCAGATGGTGGAGAACTTCCTGGCGGGCGGCGCGGCGGTGAGCGTGCTCGCGCGCCAGCA
CGGCCTGGCGCTCACGGTGGCCGACTGCGGCGTGGCGGCATCCGTCCCACCGCGTGACGGCGCCCCGGGCATGCCGCGCC
TGCTGAGCCACTGCCGGGTGGCGGTCGGCACCGCCGATGCGTCGGCAGGTCCCGCCATGACGGCGCAGCAGTGCGCGCAG
GCCGTGGAGAACGGCCGCTCCATCGTCCGCTCCCTGCCGGGCAACGCGCTGCTGCTGGGTGAAATGGGTATCGGCAACAC
CTCGGTCGCCAGCCTGCTGCTCGCGCGCCTGTGCGGCGTCGCGCTGGAGGACTGCACCGGGGCCGGCACGGGGCTGGACG
CCGACGGCATCGCGCGCAAGCGGGCCGTGCTGCGGCAGGCGCTGGAGGCCAATGCCGCCGCCACCGCGCCGCTCGACGCG
CTGGCCGCCCTGGGCGGGCTGGAGGTGGCCACCCTGGCGGGCGCCGTGCTGCAGGCCGCGGCCGAGCGCCGCGTGGTGGT
GGTCGATGGCTTCATCACCAGCGCCGCGGTGCTGGTGGCCAGCCGCATCGAACCGGCCGTGCTGGAATGCTGCGTGTTCT
CGCACCGCTCCGGCGAGCCGGGGCATGCGCACCTGCTCGCCGCGCTGGGCGCGGAGCCGCTGCTGGACCTGGGCCTGCGC
CTGGGCGAGGGTTCGGGCGCGGCGCTGGCGTGGCCGCTGCTCGTTTCCGCCTGCGCGATCCTGCGCGAGATGGCGAGCTT
CGAGCAGGCCGGCGTCTCGCGCCAGCGCGACTGA

Upstream 100 bases:

>100_bases
ATGGTTCGACCCCGCCTGGCGCGCGGCGCGGCGCGCGGGCCGATGATGATCGCGGCACCGTGCCCTGCCGCGGTGCGTTT
CCTGGACTCCGAAAACCATC

Downstream 100 bases:

>100_bases
TCAGGCCGTGGCGCCGGCCTCGCGGCCGGCCATCTCCTGCAGCAGCGCCACCAGCGGGTCGTCCGGCAGGGGCTGGTGCG
TTTCGGGGCGGCGCGGGTCC

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MTTNDPTPAGATVRPQDAALAARLRHRMDHKTKPLGALGRLEALAVRIGCIFGTESPELHAPQMLVCAADHGIAARGVSA
YPSEVTAQMVENFLAGGAAVSVLARQHGLALTVADCGVAASVPPRDGAPGMPRLLSHCRVAVGTADASAGPAMTAQQCAQ
AVENGRSIVRSLPGNALLLGEMGIGNTSVASLLLARLCGVALEDCTGAGTGLDADGIARKRAVLRQALEANAAATAPLDA
LAALGGLEVATLAGAVLQAAAERRVVVVDGFITSAAVLVASRIEPAVLECCVFSHRSGEPGHAHLLAALGAEPLLDLGLR
LGEGSGAALAWPLLVSACAILREMASFEQAGVSRQRD

Sequences:

>Translated_357_residues
MTTNDPTPAGATVRPQDAALAARLRHRMDHKTKPLGALGRLEALAVRIGCIFGTESPELHAPQMLVCAADHGIAARGVSA
YPSEVTAQMVENFLAGGAAVSVLARQHGLALTVADCGVAASVPPRDGAPGMPRLLSHCRVAVGTADASAGPAMTAQQCAQ
AVENGRSIVRSLPGNALLLGEMGIGNTSVASLLLARLCGVALEDCTGAGTGLDADGIARKRAVLRQALEANAAATAPLDA
LAALGGLEVATLAGAVLQAAAERRVVVVDGFITSAAVLVASRIEPAVLECCVFSHRSGEPGHAHLLAALGAEPLLDLGLR
LGEGSGAALAWPLLVSACAILREMASFEQAGVSRQRD
>Mature_356_residues
TTNDPTPAGATVRPQDAALAARLRHRMDHKTKPLGALGRLEALAVRIGCIFGTESPELHAPQMLVCAADHGIAARGVSAY
PSEVTAQMVENFLAGGAAVSVLARQHGLALTVADCGVAASVPPRDGAPGMPRLLSHCRVAVGTADASAGPAMTAQQCAQA
VENGRSIVRSLPGNALLLGEMGIGNTSVASLLLARLCGVALEDCTGAGTGLDADGIARKRAVLRQALEANAAATAPLDAL
AALGGLEVATLAGAVLQAAAERRVVVVDGFITSAAVLVASRIEPAVLECCVFSHRSGEPGHAHLLAALGAEPLLDLGLRL
GEGSGAALAWPLLVSACAILREMASFEQAGVSRQRD

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=346, Percent_Identity=34.971098265896, Blast_Score=177, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36113; Mature: 35982

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNDPTPAGATVRPQDAALAARLRHRMDHKTKPLGALGRLEALAVRIGCIFGTESPELH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCC
APQMLVCAADHGIAARGVSAYPSEVTAQMVENFLAGGAAVSVLARQHGLALTVADCGVAA
CCCEEEEECCCCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCC
SVPPRDGAPGMPRLLSHCRVAVGTADASAGPAMTAQQCAQAVENGRSIVRSLPGNALLLG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
EMGIGNTSVASLLLARLCGVALEDCTGAGTGLDADGIARKRAVLRQALEANAAATAPLDA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
LAALGGLEVATLAGAVLQAAAERRVVVVDGFITSAAVLVASRIEPAVLECCVFSHRSGEP
HHHHCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
GHAHLLAALGAEPLLDLGLRLGEGSGAALAWPLLVSACAILREMASFEQAGVSRQRD
CHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTNDPTPAGATVRPQDAALAARLRHRMDHKTKPLGALGRLEALAVRIGCIFGTESPELH
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCC
APQMLVCAADHGIAARGVSAYPSEVTAQMVENFLAGGAAVSVLARQHGLALTVADCGVAA
CCCEEEEECCCCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCC
SVPPRDGAPGMPRLLSHCRVAVGTADASAGPAMTAQQCAQAVENGRSIVRSLPGNALLLG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
EMGIGNTSVASLLLARLCGVALEDCTGAGTGLDADGIARKRAVLRQALEANAAATAPLDA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
LAALGGLEVATLAGAVLQAAAERRVVVVDGFITSAAVLVASRIEPAVLECCVFSHRSGEP
HHHHCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
GHAHLLAALGAEPLLDLGLRLGEGSGAALAWPLLVSACAILREMASFEQAGVSRQRD
CHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA