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The map label for this gene is btuR [H]

Identifier: 120610228

GI number: 120610228

Start: 1709352

End: 1709921

Strand: Direct

Name: btuR [H]

Synonym: Aave_1543

Alternate gene names: 120610228

Gene position: 1709352-1709921 (Clockwise)

Preceding gene: 120610227

Following gene: 120610229

Centisome position: 31.93

GC content: 70.53

Gene sequence:

>570_bases
ATGCAGATCGAATCTCCCCCCACCGAGCGCCGCTCGGAGAAGCCGGACGGCGAGCGCCGCGGCCTCGTGCTGGTGCATAC
CGGCGACGGCAAGGGCAAGAGCACGGCGGCCTTCGGCCTCGCGCTGCGCGCGCACGGCCGCGGCAAGCCGGTGAAGATCT
TCCAGTTCATGAAGGTGCCCAGCGCGCGCTTCGGCGAGCACCGTGTGTTCGAGCAGCTCGGCATTCCCATCGAGGGACTG
GGCGACGGCTTCAGCTGGAAGAGCCGCGACCTGGAGCATTCGGCCGCGCTCGCCCGCGCCGGCTGGGAACGGGCGCGGGA
CGCCATCCTGGGCGGCGGGCATTTCCTGGTGGTGCTCGACGAGGTCACCTATCCGCTCATCTACGGCTGGGTGCCGCTGC
AGGAGGTGGTGCAGGCGCTGCGCGATCGGCCGCGCGACGTGCATGTGGTGCTGACGGGGCGCCGCTGCCCGAAGGAACTG
ATCGACCTGGCGGACACGGTCACCGAGATGGGCCTGGTCAAGCATGCGTTCCAGGCCGGCGTGCCGGCGCAGCGCGGCAT
CGAGGACTGA

Upstream 100 bases:

>100_bases
CTGCGCGTGGCGGTACCGTGCGTCGGTCCCGCCGCGCCCGGCGGCTGATGCCAGCGTGCCGGACCGGATCTTTTTCTTCT
CCCATTCATCTTTGTTTCGC

Downstream 100 bases:

>100_bases
CGCTTGCATACGGGAGGCAAAGGCATGGCACCCGGCGAATCCGGCGCGGCAGCGGGCGAGGCCTACAGTGCCGCGGAGCG
CGAGGCCATCTACCGCGCCA

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MQIESPPTERRSEKPDGERRGLVLVHTGDGKGKSTAAFGLALRAHGRGKPVKIFQFMKVPSARFGEHRVFEQLGIPIEGL
GDGFSWKSRDLEHSAALARAGWERARDAILGGGHFLVVLDEVTYPLIYGWVPLQEVVQALRDRPRDVHVVLTGRRCPKEL
IDLADTVTEMGLVKHAFQAGVPAQRGIED

Sequences:

>Translated_189_residues
MQIESPPTERRSEKPDGERRGLVLVHTGDGKGKSTAAFGLALRAHGRGKPVKIFQFMKVPSARFGEHRVFEQLGIPIEGL
GDGFSWKSRDLEHSAALARAGWERARDAILGGGHFLVVLDEVTYPLIYGWVPLQEVVQALRDRPRDVHVVLTGRRCPKEL
IDLADTVTEMGLVKHAFQAGVPAQRGIED
>Mature_189_residues
MQIESPPTERRSEKPDGERRGLVLVHTGDGKGKSTAAFGLALRAHGRGKPVKIFQFMKVPSARFGEHRVFEQLGIPIEGL
GDGFSWKSRDLEHSAALARAGWERARDAILGGGHFLVVLDEVTYPLIYGWVPLQEVVQALRDRPRDVHVVLTGRRCPKEL
IDLADTVTEMGLVKHAFQAGVPAQRGIED

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=186, Percent_Identity=43.010752688172, Blast_Score=152, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 20878; Mature: 20878

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIESPPTERRSEKPDGERRGLVLVHTGDGKGKSTAAFGLALRAHGRGKPVKIFQFMKVP
CCCCCCCCHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHEEEEECCCCCCEEEHHHHHCC
SARFGEHRVFEQLGIPIEGLGDGFSWKSRDLEHSAALARAGWERARDAILGGGHFLVVLD
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
EVTYPLIYGWVPLQEVVQALRDRPRDVHVVLTGRRCPKELIDLADTVTEMGLVKHAFQAG
CCCCCHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHC
VPAQRGIED
CCCCCCCCC
>Mature Secondary Structure
MQIESPPTERRSEKPDGERRGLVLVHTGDGKGKSTAAFGLALRAHGRGKPVKIFQFMKVP
CCCCCCCCHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHEEEEECCCCCCEEEHHHHHCC
SARFGEHRVFEQLGIPIEGLGDGFSWKSRDLEHSAALARAGWERARDAILGGGHFLVVLD
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
EVTYPLIYGWVPLQEVVQALRDRPRDVHVVLTGRRCPKELIDLADTVTEMGLVKHAFQAG
CCCCCHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHC
VPAQRGIED
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]